Description : An allosteric inhibitor of PRPP glutamyl amido transferase is (A) AMP (B) ADP (C) GMP (D) All of these
Last Answer : Answer : C
Description : An allosteric inhibitor of adenylosuccinate synthetase is (A) AMP (B) ADP (C) GMP (D) GDP
Last Answer : Answer : A
Description : GMP is an allosteric inhibitor of all the following except (A) PRPP synthetase (B) PRPP glutamyl amido synthetase (C) IMP dehydrogenase (D) Adenylosuccinate synthetase
Last Answer : Answer : D
Description : Cytosolic carbamoyl phosphate synthetase is inhibited by (A) UTP (B) CTP (C) PRPP (D) TMP
Description : AMP is an allosteric inhibitor of (A) PRPP synthetase (B) Adenylosucciante synthetase (C) Both (A) and (B) (D) None of these
Description : PRPP glutamyl amidotransferase, the first enzyme uniquely committed to purine synthesis is feed back inhibited by (A) AMP (B) IMP (C) XMP (D) CMP
Description : An allosteric inhibitor of IMP dehydrogenase is (A) AMP (B) ADP (C) GMP (D) GDP
Description : Allsoteric activator of glutamate dehydrogenase is (A) ATP (B) GTP (C) ADP and GDP (D) AMP and GMP
Description : Allosteric inhibitor of glutamate dehydrogenase is (A) ATP (B) ADP (C) AMP (D) GMP
Description : The enzyme aspartate transcarbamoylase of pyrimidine biosynthesis is inhibited by (A) ATP (B) ADP (C) AMP (D) CTP
Description : Phosphofructokinase key enzyme in glycolysis is inhibited by (A) Citrate and ATP (B) AMP (C) ADP (D) TMP
Description : Phosphofructokinase is allosterically inhibited by (A) Fructose-1, 6-biphosphate (B) Lactate (C) Pyruvate (D) Citrate
Description : Isocitrate dehydrogenase is allosterically inhibited by (A) Oxalosuccinate (B) α-Ketoglutarate (C) ATP (D) NADH
Description : All the following statements about primary gout are true except (A) Its inheritance is X-linked recessive (B) It can be due to increased activity of PRPP synthetase (C) It can be ... activity of hypoxanthine guanine phosphoribosyl transferase (D) De novo synthesis of purines is increased in it
Description : The following abnormality in PRPP synthetase can cause primary gout: (A) High Vmax (B) Low Km (C) Resistance to allosteric inihbition. (D) All of these
Description : Cytosolic carbamoyl phosphate synthetase is activated by (A) Glutamine (B) PRPP (C) ATP (D) Aspartate
Last Answer : Answer : B
Description : The first reaction unique to purine nucleotide synthesis is catalysed by (A) PRPP synthetase (B) PRPP glutamyl amido transferase (C) Phosphoribosyl glycinamide synthetase (D) Formyl transferase
Description : All of the following enzymes are unique to purine nucleotide synthesis except (A) PRPP synthetase (B) PRPP glutamyl amido transferase (C) Adenylosuccinate synthetase (D) IMP dehydrogenase
Description : In the pathway of de novo synthesis of purine nucleotides, all the following are allosteric enzymes except (A) PRPP glutamyl amido transferase (B) Adenylosuccinate synthetase (C) IMP dehydrogenase (D) Adenylosuccinase
Description : An enzyme which acts as allosteric regulator and sensitive to both phosphate concentration and to the purine nucleotides is (A) PRPP synthetase (B) PRPP glutamyl midotransferase (C) HGPR Tase (D) Formyl transferase
Description : Aspartate transcarbamoylase is inhibited by (A) CTP (B) PRPP (C) ATP (D) TMP
Description : All the following statements about charging of tRNA are correct except (A) It is catalysed by amino acyl tRNA synthetase (B) ATP is converted into ADP and Pi in this reaction (C) The enzyme recognizes the tRNA and the amino acid (D) There is a separate enzyme for each tRNA
Description : All of the following statements about thioredoxin reductase are true except: (A) It requires NADH as a coenzyme (B) Its substrates are ADP, GDP, CDP and UDP (C) It is activated by ATP (D) It is inhibited by dADP
Description : Enhanced facultative reabsorption of water by Vasopressin is mediated by (A) Cyclic AMP (B) Ca++ (C) Cyclic GMP (D) Mg++
Description : Xanthosine monophosphate is an intermediate during de novo synthesis of (A) TMP (B) CMP (C) AMP (D) GMP
Description : Inosine monophophate is an intermediate during the de novo synthesis of (A) AMP and GMP (B) CMP and UMP (C) CMP and TMP (D) All of these
Description : The catabolite repression is mediated by a catabolite gene activator protein (CAP) in conjunction with (A) AMP (B) GMP (C) cAMP (D) Cgmp
Description : Ring closure of formimidoimidazole carboxamide ribosyl-5-phosphate yields the first purine nucleotide: (A) AMP (B) IMP (C) XMP (D) GMP
Description : A pyrimidine nucleotide is (A) GMP (B) AMP (C) CMP (D) IMP
Description : The second messenger for glucocorticoids is (A) Cyclic AMP (B) Cyclic GMP (C) Inositol triphosphate (D) No second messenger is required
Description : Second messenger for glucagons is (A) Cyclic AMP (B) Diacylglycerol (C) Cyclic GMP (D) Inositol triphosphate
Description : The second messenger for PTH is (A) Cyclic AMP (B) Cyclic GMP (C) Diacylglycerol (D) Inositol triphosphate
Description : Protein kinase C is activated by (A) Cyclic AMP (B) Cyclic GMP (C) Diacyl glycerol (D) Inositol triphosphate
Description : ACTH induces rise in (A) Cyclic AMP (B) Cyclic GMP (C) Calcium (D) Magnesium
Description : Cyclic AMP can be formed from (A) AMP (B) ADP (C) ATP (D) All of these
Description : UDP and UTP are formed by phosphorylation from (A) AMP (B) ADP (C) ATP (D) GTP
Description : ADP ribosylation is the mode of action of (A) Cholera toxin (B) Acetyl choline (C) Muscerinic receptors (D) Cyclic AMP
Description : Standard free energy (∆G°) of hydrolysis of ADP to AMP + Pi is (A) –43.3 KJ/mol (B) –30.5 KJ/mol (C) –27.6 KJ/mol (D) –15.9 KJ/mol
Description : The enzyme phosphoenolpyruvate carboxykinase catalyses the conversion of oxaloacetate to phosphoenolpyruvate requires (A) ATP (B) ADP (C) AMP (D) GTP
Description : The enzyme acyl-CoA synthase catalyses the conversion of a fatty acid of an active fatty acid in the presence of (A) AMP (B) ADP (C) ATP (D) GTP
Description : In the biosynthesis of purine nucleotides the AMP feed back regulates (A) Adenylosuccinase (B) Adenylosuccinate synthetase (C) IMP dehydrogenase (D) HGPR Tase
Description : Phosphorylation of adenosine to AMP is catalysed by (A) Adenosine kinase (B) Deoxycytidine kinase (C) Adenylosuccinase (D) Adenylosuccinate synthetase
Description : Glycogen synthetase activity is depressed by (A) Glucose (B) Insulin (C) Cyclic AMP (D) Fructokinase
Last Answer : C
Description : Action of glycogen synthase is inhibited by (A) Insulin (B) Glucose (C) Mg2+ (D) Cyclic AMP
Description : Inhibition of thromboxane synthesis by aspirin in platelets lasts for 5-7 days because: A. Aspirin persists in the body for 5-7 days B. Aspirin induced depletion of arachidonic acid lasts 5-7 ... 5-7 days D. Platelets cannot generate fresh thromboxane synthetase and their turnover time is 5-7 days
Last Answer : D. Platelets cannot generate fresh thromboxane synthetase and their turnover time is 5-7 days
Description : Organic nitrates relax vascular smooth muscle by (a) Increasing intracellular cyclic AMP (b) Increasing intracellular cyclic GMP (c) Decreasing intracellular cyclic AMP (d) Both (b) and (c)
Last Answer : Ans: B
Description : Cyclic nucleotides exert the following action on salt transport across intestinal mucosal cells: A. Both cyclic AMP and cyclic GMP enhance Cland HCO3 - secretion B. Cyclic AMP enhances but cyclic GMP ... Cl- reabsorption D. Both cyclic AMP and cyclic GMP enhance Na+ and Cl- reabsorption
Last Answer : A. Both cyclic AMP and cyclic GMP enhance Cland HCO3 – secreti
Description : Organic nitrates relax vascular smooth muscle by: A. Increasing intracellular cyclic GMP B. Increasing intracellular cyclic AMP C. Decreasing intracellular cyclic AMP D. Both ‘A’ and ‘C’ are correct
Last Answer : A. Increasing intracellular cyclic GMP
Description : 6.4 Several actions of growth hormone are exerted through the elaboration of: A. Cyclic AMP B. Cyclic GMP C. Somatostatin D. Insulin like growth factor-1
Last Answer : D. Insulin like growth factor-1
Description : Nucleotide found free in the cells is: (a) CAMP (b) AMP (c) ADP (d) ATP
Last Answer : Ans. ((d))