De novo synthesis of pyrimidine nucleotides occurs in (A) Mitochondria (B) Cytosol (C) Microsomes (D) Ribosomes

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Answer :

Answer :  B

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Description : De novo synthesis of purine nucleotide occurs in (A) Mitochondria (B) Cytosol (C) Microsmes (D) Ribosomes

Last Answer : Answer : B

Description : De hovo synthesis of fatty acids occurs in (A) Cytosol (B) Mitochondria (C) Microsomes (D) All of these

Last Answer : Answer : A

Description : De novo synthesis and oxidation of fatty acids differ in the following respect: (A) Synthesis occurs in cytosol and oxidation in mitochondria (B) Synthesis is decreased and oxidation increased by ... synthesis and FAD in oxidation (D) Malonyl CoA is formed during oxidation but not during synthesis

Last Answer : Answer : A

Description : De novo synthesis of pyrimidine nucleotides is regulated by (A) Carbamoyl phosphate synthetase (B) Aspartate transcarbamoylase (C) Both (A) and (B) (D) None of these

Last Answer : Answer : C

Description : During de novo synthesis of pyrimidine nucleotides, the first ring compound to be formed is (A) Carbamoyl aspartic acid (B) Dihydro-orotic acid (C) Orotic acid (D) Orotidine monophosphate

Last Answer : Answer : B

Description : All the enzymes required for de novo synthesis of pyrimidine nucleotides are cytosolic except (A) Carbamoyl phosphate synthetase (B) Aspartate transcarbamoylase (C) Dihydro-orotase (D) Dihydro-orotate dehydrogenase

Last Answer : Answer : D

Description : An enzyme common to de novo synthesis of pyrimidine nucleotides and urea is (A) Urease (B) Carbamoyl phosphate synthetase (C) Aspartate transcarbamoylase (D) Argininosuccinase

Last Answer : Answer : B

Description : The available PRPP is used preferentially for (A) De novo synthesis of purine nucleotides (B) De novo synthesis of pyrimidine nucleotides (C) Salvage of purine bases (D) Salvage of pyrimidine bases

Last Answer : Answer : C

Description : The main pathway for denovo synthesis of fatty acids occur in (A) Cytosol (B) Mitochondria (C) Microsomes (D) Nucleus

Last Answer : Answer : A

Description : During synthesis of porphyrins, synthesis of δ-amino levulinic acid occurs in (A) Mitochondria (B) Cytosol (C) Both in mitochondria and cytosol (D) Ribosomes

Last Answer : Answer : A

Description : The biosynthesis of urea occurs mainly in the liver: (A) Cytosol (B) Mitochondria (C) Microsomes (D) Nuclei

Last Answer : Answer : B

Description : Oxidation of fatty acids occurs (A) In the cytosol (B) In the matrix of mitochondria (C) On inner mitochondrial membrane (D) On the microsomes

Last Answer : Answer : B

Description : The biosynthesis of Urea occurs mainly in the Liver: (A) Cytosol (B) Microsomes (C) Nucleus (D) Mitochondria

Last Answer : Answer : D

Description : The first pyrimidine nucleotide to be formed in de novo synthesis pathway is (A) UMP (B) CMP (C) CTP (D) TMP

Last Answer : Answer : A

Description : In inherited deficiency of hypoxanthine guanine phosphoribosyl transferase (A) De novo synthesis of purine nucleotides is decreased (B) Salvage of purines is decreased (C) Salvage of purines is increased (D) Synthesis of uric acid is decreased

Last Answer : Answer : B

Description : In the pathway of de novo synthesis of purine nucleotides, all the following are allosteric enzymes except (A) PRPP glutamyl amido transferase (B) Adenylosuccinate synthetase (C) IMP dehydrogenase (D) Adenylosuccinase

Last Answer : Answer : D

Description : For de novo synthesis of purine nucleotides, aspartate provides (A) Nitrogen 1 (B) Nitrogen 3 (C) Nitrogen 7 (D) Nitrogen 9

Last Answer : Answer : A

Description : For de novo synthesis of purine nucleotides, glycine provides (A) One nitrogen atom (B) One nitrogen and one carbon atom (C) Two carbon atoms (D) One nitrogen and two carbon atoms

Last Answer : Answer : D

Description : The nitrogen atoms for de novo synthesis of purine nucleotides are provided by (A) Aspartate and glutamate (B) Aspartate and glycine (C) Aspartate, glutamine and glycine (D) Aspartate, glutamate and glycine

Last Answer : Answer : C

Description : Nucleotides required for the synthesis of nucleic acids can be obtained from (A) Dietary nucleic acids and nucleotides (B) De novo synthesis (C) Salvage of pre-existing bases and nucleosides (D) De novo synthesis and salvage

Last Answer : Answer : D

Description : Protein synthesis in an animal cell occurs (a) only on the ribosomes present in cytosol (b) only on ribosome attached to the nuclear envelope and endoplasmic reticulum (c) on ribosome present in the ... as well as in cytoplasm (d) on ribosomes present in cytoplasm as well as in mitochondria.

Last Answer : (d) on ribosomes present in cytoplasm as well as in mitochondria.

Description : .Protein synthesis in an animal cell occurs (a) only on the ribosomes present in cytosol (b) only on ribosome attached to the nuclear envelope and endoplasmic reticulum (c) on ribosome present in the ... as well as in cytoplasm (d) on ribosomes present in cytoplasm as well as in mitochondria.

Last Answer : (d) on ribosomes present in cytoplasm as well as in mitochondria.

Description : Acetyl CoA from mitochondria is transferred to cytoplasm for the de novo synthesis of fatty acid, by which enzyme?

Last Answer : ATP citrate lyase.

Description : The major site for elongation of medium chain fatty acids is (A) Mitochondria (B) Cytosol (C) Microsomes (D) All of these

Last Answer : Answer : C

Description : Glycolytic pathway is located in (A) Mitochondria (B) Cytosol (C) Microsomes (D) Nucleus

Last Answer : Answer : B

Description : Lactate dehydrogenase is located in (A) Lysosomes (B) Mitochondria (C) Cytosol (D) Microsomes

Last Answer : Answer : C

Description : Long chain fatty acids are first activated to acetyl-CoA in (A) Cytosol (B) Microsomes (C) Nucleus (D) Mitochondria

Last Answer : Answer : A

Description : Which of the following ribosomes are engaged in protein synthesis in animal cell? (a) Ribosomes which occur on nuclear membrane and ER (b) Ribosomes of only cytosol (c) Ribosomes of only nucleolus and cytosol (d) Ribosomes of only mitochondria and cytosol

Last Answer : (a) poleward movement

Description : All of the following occur in orotic aciduria except (A) Increased synthesis of pyrimidine nucleotides (B) Increased excretion of orotic acid in urine (C) Decreased synthesis of cytidine triphosphate (D) Retardation of growth

Last Answer : Answer : A

Description : 5-Phosphoribosyl-1-pyrophosphate is required for the synthesis of (A) Purine nucleotides (B) Pyrimidine nucleotides (C) Both (A) and (B) (D) None of these

Last Answer : Answer : C

Description : Chain elongation of fatty acids in mammalian liver occurs in (A) Nucleus (B) Ribosomes (C) Lysosomes (D) Microsomes

Last Answer : Answer : D

Description : All the following statements about primary gout are true except (A) Its inheritance is X-linked recessive (B) It can be due to increased activity of PRPP synthetase (C) It can be ... activity of hypoxanthine guanine phosphoribosyl transferase (D) De novo synthesis of purines is increased in it

Last Answer : Answer : C

Description : Xanthosine monophosphate is an intermediate during de novo synthesis of (A) TMP (B) CMP (C) AMP (D) GMP

Last Answer : Answer : D

Description : Inosine monophophate is an intermediate during the de novo synthesis of (A) AMP and GMP (B) CMP and UMP (C) CMP and TMP (D) All of these

Last Answer : Answer : A

Description : All the following statements about acetyl CoA carboxylase are true except (A) It is required for de novo synthesis of fatty acids (B) It is required for mitochondrial elongation of fatty acids ( ... for microsomal elongation of fatty acids (D) Insulin converts its inactive form into its active form

Last Answer : Answer : B

Description : Formation of acetyl CoA from pyruvate for de novo synthesis of fatty acids requires (A) Pyruvate dehydrogenase complex (B) Citrate synthetase (C) ATP citrate lyase (D) All of these

Last Answer : Answer : D

Description : Acetyl CoA required for de novo synthesis of fatty acids is obtained from (A) Breakdown of existing fatty acids (B) Ketone bodies (C) Acetate (D) Pyruvate

Last Answer : Answer : D

Description : The maximum possible chain length of fatty acids formed in the pathway of de novo synthesis is (A) 16 Carbon atoms (B) 18 Carbon atoms (C) 20 Carbon atoms (D) 24 Carbon atoms

Last Answer : Answer : A

Description : C22 and C24, fatty acids required for the synthesis of sphingolipids in brain are formed by (A) De novo synthesis (B) Microsomal chain elongation (C) Mitochondrial chain elongation (D) All of these

Last Answer : Answer : B

Description : One functional sub-unit of multi-enzyme complex for de novo synthesis of fatty acids contains (A) One —SH group (B) Two —SH groups (C) Three —SH groups (D) Four —SH groups FATS AND FATTY ACID METABOLISM 87

Last Answer : Answer : B

Description : De novo synthesis of fatty acids is catalysed by a multi-enzyme complex which contains (A) One-SH group (B) Two-SH groups (C) Three-SH groups (D) Four-SH groups

Last Answer : Answer : D

Description : De novo synthesis of fatty acids requires all of the following except (A) Biotin (B) NADH (C) Panthothenic acid (D) ATP

Last Answer : Answer : D

Description : What is the rate limiting enzyme of de novo synthesis of fatty acid?

Last Answer : Acetyl CoA carboxylase.

Description : Monooxygenases are found in (A) Cytosol (B) Nucleus (C) Mitochondira (D) Microsomes

Last Answer : Answer : D

Description : All the enzymes involved in the synthesis of cholesterol are found in (A) Mitochondria (B) Golgi apparatus (C) Nucleus (D) Endoplasmic reticulum and cytosol

Last Answer : Answer : D

Description : The synthesis of 3-hydroxy-3-methylglutaryl-CoA can occur (A) Only in mitochondria of all mammalian tissues (B) Only in the cytosol of all mammalian tissue (C) In both cytosol and mitochondria (D) In lysosomes

Last Answer : Answer : C

Description : Carbamoyl phosphate required for urea synthesis is formed in (A) Cytosol (B) Mitochondria (C) Both (A) and (B) (D) None of these

Last Answer : Answer : B

Description : The enzymes of urea synthesis are found in (A) Mitochondria only (B) Cytosol only (C) Both mitochondria and cytosol (D) Nucleus

Last Answer : Answer : C

Description : The site of enzymes directing the metabolic oxidation (respiration), ATP synthesis and considered as power house of cell are (A) Lysosomes (B) Microsomes (C) Mitochondria (D) Golgi apparatus

Last Answer : (C) Mitochondria

Description : Chain elongation of fatty acids occurring in mammalian liver takes place in which of the following subcellular fractions of the cell? (A) Nucleus (B) Ribosomes (C) Lysosomes (D) Microsomes

Last Answer : Answer : D