Description : Amino acid residues which are essential for the biological activity of PTH are (A) N-terminal 34 amino acids (B) N-terminal 50 amino acids (C) C-terminal 34 amino acids (D) C-terminal 50 amino acids
Last Answer : Answer : A
Description : Sialic acids are present in (A) Proteoglycans (B) Glycoproteins (C) Both (A) and (B) (D) None of these
Last Answer : Answer : B
Description : In N-linked glycoproteins, oligosaccharide is attached to protein through its (A) Asparagine residue (B) Glutamine residue (C) Arginine residue (D) Lysine residue
Description : Oligosaccharide-pyrophosphoryl dolichol is required for the synthesis of (A) N-linked glycoproteins (B) O-linked glycoproteins (C) GPI-linked glycoproteins (D) All of these
Description : I-cell disease results from absence of the following from lysosomal enzymes: (A) Signal sequence (B) Mannose-6-phosphate (C) Sialic acid (D) A serine residue
Last Answer : Answer : D
Description : The half-life of a protein depends upon its (A) Signal sequence (B) N-terminus amino acid (C) C-terminus amino acid (D) Prosthetic group
Description : In glycoproteins, carbohydrate residues are attached to which group of the polypeptide chain?
Last Answer : Hydroxyl group of serine or threonine.
Description : Chymotrypsin is specific for peptide bonds containing (A) Uncharged amino acid residues (B) Acidic amino acids (C) Basic amino acid (D) Small amino acid residues
Description : The enzyme trypsin is specific for peptide bonds of (A) Basic amino acids (B) Acidic amino acids (C) Aromatic amino acids (D) Next to small amino acid residues
Description : Bence-Jones proteins possess all the following properties except (A) They are dimers of light chains (B) Their amino acids sequences are identical (C) Their N-terminal halves have variable amino acid sequences (D) Their C-terminal halves have constant amino acid sequences
Description : Hormonal activity of ACTH is completely lost on removal of (A) 5 C-terminal amino acids (B) 10 C-terminal amino acids (C) 15 C-terminal amino acids (D) None of these
Description : Collagen and elastin have the following similarity: (A) Both are triple helices (B) Both have hydroxyproline residues (C) Both have hydrolysine residues (D) Both are glycoproteins
Description : The combination of an amino alcohol, fatty acid and sialic acid form (A) Phospholipids (B) Sulpholipids (C) Glycolipids (D) Aminolipids
Last Answer : Answer : C
Description : Biological activity of gastrin is present in the (A) Four N-terminal amino acids (B) Four C-terminal amino acids (C) Five N-terminal amino acids (D) Five C-terminal amino acids
Description : N-terminal amino acids of a polypeptide are estimated by (A) Edmann reaction (B) Sanger’s reagent (C) Formaldehyde test (D) Ninhydrine reaction
Description : N-acetylneuraminic acid is an example of (A) Sialic acid (B) Mucic acid (C) Glucuronic acid (D) Hippuric acid
Last Answer : C
Description : How N-acetyl neuraminic acid (sialic acid) is synthesised?
Last Answer : N-acetyl mannosamine-6-phosphate + phospho enol pyruvate.
Description : Which of the following is present as a marker in lysosomal enzymes to direct them to their destination? (A) Glucose-6-phosphate (B) Mannose-6-phosphate (C) Galactose-6-phosphate (D) N-Acetyl neuraminic acid
Description : From two amino acids peptide bond formation involves removal of one molecule of (A) Water (B) Ammonia (C) Carbondioxide (D) Carboxylic acid
Description : Number of amino acid residues in glucagons is (A) 29 (B) 34 (C) 51 (D) 84
Description : The number of amino acid residues in PTH: (A) 51 (B) 84 (C) 90 (D) 115
Description : Number of amino acid residues in prolactin is (A) 51 (B) 84 (C) 191 (D) 198
Description : Number of amino acid residues in human growth hormone is (A) 51 (B) 84 (C) 191 (D) 198
Description : Pre-proinsulin contains a signal sequence having (A) 9 amino acid residues (B) 19 amino acid residues (C) 27 amino acid residues (D) 33 amino acid residues
Description : The number of amino acid residues in preproinsulin is (A) 51 (B) 84 (C) 109 (D) 119
Description : Insulin is made up of (A) A single polypeptide chain having 51 amino acid residues (B) A single polypeptide chain having 84 amino acid residues (C) A-chain having 21 and B-chain having 30 amino acid residues (D) A-chain having 30 and B-chain having 21 amino acid residues
Description : The number of amino acid residues in calcitonin in (A) 9 (B) 32 (C) 51 (D) 84
Description : Edman’s reaction can be used to (A) Determine the number of tyrosine residues in a protein (B) Determine the number of aromatic amino acid residues in a protein (C) Determine the amino acid sequence of a protein (D) Hydrolyse the peptide bonds in a protein
Description : Each turn of α-helix contains the amino acid residues (number): (A) 3.6 (B) 3.0 (C) 4.2 (D) 4.5
Description : Which of the following is the first step in the determination of the primary structure of proteins? (a) determining the number and kind of amino acids in the peptide (b) reducing the disulfide bridges ... (c) protecting the N-terminal of the peptide (d) protecting the C-terminal of the peptide
Last Answer : reducing the disulfide bridges in the protein
Description : The amino terminal of all polypeptide chain at the time of synthesis in E. coli is tagged to the amino acid residue: (A) Methionine (B) Serine (C) N-formyl methinine(D) N-formal serine
Description : Biological activity of ACTH requires (A) 10-N-terminal amino acid (B) 24-N-terminal amino acid (C) 24-C-terminal amino acid (D) 15-C-terminal amino acid
Description : The prosthetic group of aerobic dehydrogenases is (A) NAD (B) NADP (C) FAD (D) Pantothenic acid
Description : Proteoglycans are made up of proteins and (A) Glucosamine (B) Mannosamine (C) Sialic acid (D) Mucopolysaccharides
Description : All the following are constituents of ganglioside molecule except (A) Glycerol (B) Sialic acid (C) Hexose sugar (D) Sphingosine
Description : Gangliosides derived from glucosylceramide contain in addition one or more molecules of (A) Sialic acid (B) Glycerol (C) Diacylglycerol (D) Hyaluronic acid
Description : The covalent bond that is repeatedly present between different amino acid residues in a protein is called (a) p-bond (b) hydrogen bond (c) peptide bond (d) metallic bond
Last Answer : Ans:(c)
Description : A carbohydrate composed of three to ten sugar molecules is called a(n) : (a) disaccharide (b) oligosaccharide (c) polysaccharide (d) monosaccharide
Last Answer : oligosaccharide
Description : Zn is present as prosthetic group in this enzyme: (A) Carbonic anhydrase (B) Carboxy peptidase (C) Lactate dehydrogenase (D) All of these
Description : Iron-pophyrin is present as prosthetic group in (A) Cytochromes (B) Catalases (C) Peroxidase (D) None of these
Description : Part of enzyme which combines with nonprotein part to form functional enzyme is (A) Apoenzyme (B) Coenzyme (C) Prosthetic group (D) None of these
Description : Combination of apoenzyme and coenzyme produces (A) Prosthetic group (B) Holoenzyme (C) Enzyme substrate complex (D) Enzyme product complex
Description : Cofactor (Prosthetic group) is a part of holoenzyme, it is (A) Inorganic part loosely attached (B) Accessory non-protein substance attached firmly (C) Organic part attached loosely (D) None of these
Description : Of Which warburg’s yellow enzyme contains as a prosthetic group? (A) Thiamine pyrophosphate (B) Biotin (C) NAD+ (D) Riboflavin-5-phosphate
Description : Prosthetic group in cone cell phototreceptors is (A) Iodine (B) Opsin (C) 11-cis-retinal (D) all-trans-retinal
Description : The figure shows a hypothetical tetrapeptide portion of a protein with parts labelled A-D. Which one of the following options is correct? - HN - CH - CO - NH - CH - CO - NH - CH - CO - ... -terminal amino acid and D is N-terminal amino acid. (d) A is a sulphur containing amino acid methionine.
Last Answer : (a) D is the acidic amino acid-glutamic acid.
Description : Consider the following statements: (1) Copper is present in cytochrome oxidane (2) Pantothenic acid is precursor of co-enzyme-A (3) Thiamine prohosphate is the prosthetic group in decarboxylases (4) Zinc is present in RNA and DNA polymerases
Last Answer : Ans. ((b))
Description : Deamination is ______ of amino group. (A) Removal (B) Addition (C) Supplementation (D) None of these
Description : In the B chain of insulin molecule, the C-terminal amino acid: (A) Threonine (B) Tyrosine (C) Glutamate (D) Valine
Description : Amino acids excepting histidine are not good buffering agents in cell because (A) They exist as zwitter ions (B) Their pk and not in the physiological pH of a cell (C) Only Histidine has pk of its R group at 6.0 unlike the others which have at a different pH (D) None of these