Description : The mushroom poison amanitin is an inhibitor of (A) Protein synthesis (B) mRNA synthesis (C) DNA synthesis (D) Adenosine synthesis
Last Answer : Answer : B
Description : α-Amanitin inhibits (A) DNA polymerase II of prokaryotes (B) DNA polymerase α of eukaryotes (C) RNA polymerase II of eukaryotes (D) RNA-dependent DNA polymerase
Last Answer : Answer : C
Description : Ciprofloxacin inhibits the synthesis of (A) DNA (B) mRNA (C) tRNA (D) rRNA
Last Answer : Answer : A
Description : Novobicin inhibits the synthesis of (A) DNA (B) mRNA (C) tRNA (D) rRNA
Description : An uncoupler of oxidative phosphorylation such as dinitrophenol (A) Inhibits electron transport and ATP synthesis (B) Allow electron transport to proceed without ATP synthesis (C) Inhibits electron transport without impairment of ATP synthesis (D) Specially inhibits cytochrome b
Last Answer : B
Description : In prokaryotes, chloramphenicol (A) Causes premature release of the polypeptide chain (B) Causes misreading of the mRNA (C) Depolymerises DNA (D) Inhibits peptidyl transferase activity
Description : The mRNA ready for protein synthesis has the ________ cap. (A) ATP (B) CTP (C) GTP (D) UTP
Description : Which antibiotic inhibits interaction between tRNA and mRNA during bacterial protein synthesis? (a) Tetracycline (b) Erythromycin (c) Neomycin (d) Streptomycin
Last Answer : (d) Streptomycin
Description : .Which antibiotic inhibits interaction between tRNA and mRNA during bacterial protein synthesis? (a) Tetracycline (b) Erythromycin (c) Neomycin (d) Streptomycin
Last Answer : (c) Neomycin
Description : Select the antibiotic which inhibits bacterial protein synthesis by interfering with translocation of elongating peptide chain from acceptor site back to the peptidyl site of the ribosome so that ... chain is prematurely terminated: A. Chloramphenicol B. Erythromycin C. Tetracycline D. Streptomycin
Last Answer : B. Erythromycin
Description : Chloramphenicol inhibits bacterial protein synthesis by: A. Binding to 30S ribosome and inhibiting attachment of aminoacyl tRNA B. Binding to 50S ribosome and preventing peptide bond formation C. Binding to ... chain D. Binding to both 30S and 50S ribosome and inducing misreading of mRNA code
Last Answer : B. Binding to 50S ribosome and preventing peptide bond formation
Description : Ciprofloxacin inhibits the synthesis of (A) DNA in prokaryotes (B) DNA in prokaryotes and eukaryotes (C) RNA in prokaryotes (D) RNA in prokaryotes and eukaryotes
Description : Okazaki pieces are formed during the synthesis of (A) mRNA (B) tRNA (C) rRNA (D) DNA
Last Answer : Answer : D
Description : Okazaki fragment is related to (A) DNA synthesis (B) Protein synthesis (C) mRNA formation (D) tRNA formation
Description : Tetracylin prevents synthesis of polypeptide by (A) Blocking mRNA formation from DNA (B) Releasing peptides from mRNA-tRNA complex (C) Competing with mRNA for ribosomal binding sites (D) Preventing binding of aminoacyl tRNA
Description : Genetic information of nuclear DNA is transmitted to the site of protein synthesis by (A) rRNA (B) mRNA (C) tRNA (D) Polysomes
Last Answer : D
Description : Retinoic acid participates in the synthesis of (A) Iodopsin (B) Rhodopsin (C) Glycoprotein (D) Cardiolipin
Description : Vancomycin inhibits _____________ synthesis. a. protein b. DNA c. bacterial cell wall d. RNA
Last Answer : c. bacterial cell wall
Description : An important step in protein synthesis is transcription. Which of the following statement(s) is/are true concerning this process? a. The first step in gene transcription involves separating the double helix ... nucleus to the cytoplasm d. Only one protein can be produced from an initial mRNA strand
Last Answer : Answer: c Transcription of a gene begins at an initiation site associated with a specific DNA sequence, termed a promoter region. After binding to DNA, the RNA polymerase opens up a short ... different proteins from the same gene. mRNA is exported from the nucleus only after processing is complete
Description : RNA interference involves (a) synthesis of cDNA and RNA using reverse transcriptase (b) silencing of specific mRNA due to complementary RNA (c) interference of RNA in synthesis of DNA (d) synthesis of mRNA from DNA
Last Answer : (b) silencing of specific mRNA due to complementary RNA
Description : Which one of the following is wrongly matched? (a) Transcription - Writing information from DNA to tRNA. (b) Translation - Using information in mRNA to make protein. (c) Repressor protein - Binds to operator to stop enzyme synthesis. (d) Operon - Structural genes, operator and promoter.
Last Answer : (c) Repressor protein - Binds to operator to stop enzyme synthesis.
Last Answer : (d) Operon - Structural genes, operator and promoter
Description : Which of the following act as the blueprint or template for the process of protein synthesis that takes place on ribosomes? A.rRNA B.DNA C.tRNA D.mRNA
Last Answer : mRNA
Description : Which does NOT occur in a cell stimulated by a steroid hormone? A) The steroid hormone enters the cell by crossing the plasma membrane. B) The hormone binds to a receptor molecule in the ... activates certain genes. E) DNA is transcribed, mRNA is translated, and the result is protein synthesis.
Last Answer : C) The second messenger cyclic AMP is stimulated by the hormone-receptor complex. D) The hormone-receptor complex binds the chromatin and activates certain genes.
Description : ATP is required for (A) Fusion of 40S and 60S of ribosome (B) Accommodation tRNA amino acid in a site of ribosome (C) Movement of ribosome along mRNA (D) formation of tRNA amino acid complex
Description : After formation of a peptide bond, mRNA is translocated along the ribosome by (A) eEF-1 and GTP (B) eEF-2 and GTP (C) Peptidyl transferase and GTP (D) Peptidyl transferase and ATP
Description : All of the following statements about puromycin are true except (A) It is an alanyl tRNA analogue (B) It causes premature termination of protein synthesis (C) It inhibits protein synthesis in prokaryotes (D) It inhibits protein synthesis in eukaryotes
Description : Glucagon (A) Increases protein synthesis (B) Inhibits lipolysis in adipocytes (C) Increases gluconeogenesis in liver (D) Stimulates muscle glycogenolysis
Description : All the following correctly describe the intermediate 3-OH-3-methyl glutaryl CoA except (A) It is generated enzymatically in the mitochondrial matrix (B) It is formed in the cytoplasm (C) It inhibits the first step in cholesterol synthesis (D) It is involved in the synthesis of ketone bodies
Description : Which of the following statements are true of oxidants? A. In addition to their pathophysiologic roles in inflammation, injury, and infection, oxidants also have physiologic roles. B. Oxidants may ... involved the catalytic production of superoxide anion (O 2 ) by the enzyme xanthine oxidase.
Last Answer : Answer: ABCD DISCUSSION: Oxidants are reactive oxygen metabolites that have both physiologic and pathophysiologic roles. As potent oxidizing agents, oxidants are involved in cytochrome P ... leukocyte infiltration and activation, causing further tissue damage by the release of cytotoxic proteases
Description : mRNA ready for protein synthesis has the poly _______ toil. (A) G (B) A (C) U (D) C
Description : In mammals, synthesis of mRNA is catalysed by (A) RNA polymerase I (B) RNA polymerase II (C) RNA polymerase III(D) RNA polymerase IV
Description : Initiation of protein synthesis begins with binding of (A) 40S ribosomal unit on mRNA (B) 60S ribosomal unit (C) Charging of tRNA with specific amino acid (D) Attachment of aminoacyl tRNA on mRNA
Description : The function of a repressor protein in an operon system is to prevent synthesis by binding to (A) The ribosome (B) A specific region of the operon preventing transcription of structural genes (C) The RNA polymerase (D) A specific region of the mRNA preventing translation to protein
Description : The antibiotic which inhibits DNA dependent RNA polymerase is (A) Mitomycin C (B) Actinomycin d (C) Streptomycin (D) Puromycin
Description : Rifampicin inhibits (A) Unwinding of DNA (B) Initiation of replication (C) Initiation of translation (D) Initiation of transcription
Description : Ciprofloxacin inhibits (A) DNA topisomerase II (B) DNA polymerase I (C) DNA polymerase III (D) DNA gyrase
Description : Synthesis of GMP and IMP requires the following: (A) NH3 NAD+, ATP (B) Glutamine, NAD+, ATP (C) NH3, GTP, NADP+ (D) Glutamine, GTP, NADP+
Description : Initiation of protein synthesis requires (A) ATP (B) AMP (C) GDP (D) GTP
Description : The cofactors required for synthesis of adenylosuccinate are (A) ATP, Mg++ (B) ADP (C) GTP, Mg++ (D) GDP
Description : Coenzymes derived from the vitamin shown below are required by enzymes involved in the synthesis of which of the following? (A) ATP (B) UTP (C) CTP (D) NADH
Description : Formation of acetyl CoA from pyruvate for de novo synthesis of fatty acids requires (A) Pyruvate dehydrogenase complex (B) Citrate synthetase (C) ATP citrate lyase (D) All of these
Description : Synthesis of sphingosine requires the cofactor (A) NAD (B) NADP (C) NADPH+ (D) ATP
Description : A soluble system for synthesis of fatty acids have been isolated from avian liver, required for the formation of long chain fatty acids by this system is (A) ATP (B) Acetyl CoA (C) NADPH (D) All of these
Description : De novo synthesis of fatty acids requires all of the following except (A) Biotin (B) NADH (C) Panthothenic acid (D) ATP
Description : Synthesis of glutamine is accompanied by the hydrolysis of (A) ATP (B) ADP (C) TPP (D) Creatin phosphate
Description : ATP is required in following reactions of urea cycle: (A) Synthesis of carbamoyl phosphate and citrulline (B) Synthesis of citrulline and argininosuccinate (C) Synthesis of argininosuccinate and arginine (D) Synthesis of carbamoyl phosphate and argininosuccinate
Description : A coenzyme required for the synthesis of glycine from serine is (A) ATP (B) Pyridoxal phosphate (C) Tetrahydrofolate (D) NAD
Description : All of the following are required for synthesis of glutamine except (A) Glutamate (B) Ammonia (C) Pyridoxal phosphate (D) ATP
Description : The number of ATP required for urea synthesis is (A) 0 (B) 1 (C) 2 (D) 3