Important buffer system of extracellular fluid is (A) Bicarbonate/carbonic acid (B) Disodium hydrogen phosphate/sodium dihydrogen phosphate (C) Plasma proteins (D) Organic Phosphate

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Answer :  A

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Description : An acid having basicity one is - (1) Sodium dihydrogen phosphate (2) Disodium hydrogen phosphate (3) Sodium phosphate (4) Phosphoric acid

Last Answer : (2) Disodium hydrogen phosphate Explanation: The basicity of an acid is the number of hydrogen ions (H+) which can be produced by the ionization of one molecule of the acid in aqueous solution. ... Similarly, the basicity of Disodium phosphate (Na2HPO4) is one since it has one H+ displaceable ion.

Description : An acid having basicity one is (1) Sodium dihydrogen phosphate (2) Disodium hydrogen phosphate (3) Sodium phosphate (4) Phosphoric acid

Last Answer : Disodium hydrogen phosphate

Description : Quantitatively, the most significant buffer system in plasma is (A) Phosphate buffer system (B) Carbonic acid-bicarbonate buffer system (C) Lactic acid-lactate buffer system (D) Protein buffer system

Last Answer : Answer : B

Description : In a solution containing phosphate buffer, the pH will be 7.4, if the ratio of monohydrogen phosphate : dihydrogen phosphate is (A) 4 : 1 (B) 5 : 1 (C) 10 : 1 (D) 20 : 1

Last Answer : Answer : A

Description : Concentration of the following is higher in intracellular fluid than in extracellular fluid: (A) Sodium (B) Potassium (C) Chloride (D) Bicarbonate

Last Answer : Answer : B

Description : Chloride shift is (A) H ions leaving the RBC in exchange of Cl- (B) Cl– leaving the RBC in exchange of bicarbonate (C) Bicarbonate ion returns to plasma and exchanged with chloride which shifts into the cell (D) Carbonic acid to the plasma

Last Answer : Answer : C

Description : The carbon dioxide is transported via blood to lungs mostly (a) in combination with haemoglobin only (b) dissolved in blood plasma (c) in the form of bicarbonate ions (d) as carbamino-haemoglobin and as carbonic acid.

Last Answer : (c) in the form of bicarbonate ions

Description : The main physiological buffer in the blood is (A) Haemoglobin buffer (B) Acetate (C) Phosphate (D) Bicarbonate

Last Answer : Answer : D

Description : Which of the following statement(s) is/are true concerning the cell plasma membrane? a. The plasma membrane is composed of amphipathic molecules b. The hydrophobic core of the lipid bilayer of the ... contribute to the cell coat d. The membrane proteins of nerve cells are highly voltage-dependent

Last Answer : Answer: a, b, d The plasma membrane defines the boundary of the cell and serves to contain and concentrate enzymes and other macromolecule constituents. The plasma membrane is ... and bear carbohydrate moieties primarily as oligosaccharide chains that contribute to the cell coat or glycocalyx

Description : True statements about the pH of the extracellular fluid: a. in healthy people it is maintained between 7.4 and 7.5 b. is increased in hypovolaemic shock c. decreases following a cardiac arrest d. influences the binding of drugs to plasma proteins

Last Answer : . influences the binding of drugs to plasma proteins

Description : A striking feature of living cells is a marked difference between the composition of the cytosol and the extracellular milieu. Which of the following statement(s) concerning the mechanisms of maintenance ... d. The selectivity of cell membranes relates only to ions and not organic compounds

Last Answer : Answer: a The survival of the cell requires that cytosolic composition be maintained within narrow limits, despite the constant influx of nutrients and the simultaneous outflow of waste. A ... be altered drastically as a result of regulatory or signaling processes that occur within the cell

Description : The acid which fails to liberate carbon dioxide from sodium bicarbonate is : (1) Acetic acid (2) Formic acid (3) Carbonic acid (4) Sulphuric acid

Last Answer : (4) Sulphuric acid Explanation: Sodium bicarbonate and organic acid (Formic acid, Acetic acid, Carbonic acid, etc) react vigorously to liberate carbon dioxide. For example, Sodium bicarbonate (NaHCO3) when treated with acetic acid reacts vigorously to liberate carbon dioxide.

Description : The acid which fails to liberate carbon dioxide from sodium bicarbonate is : (1) Acetic acid (2) Formic acid (3) Carbonic acid (4) Sulphuric acid

Last Answer : Sulphuric acid

Description : With regard to the transport of carbon dioxide in blood: a. 25% of carbon dioxide is dissolved in blood b. carbonic anhydrase is found in plasma c. 50% of carbon dioxide is carried as bicarbonate d. deoxygenated haemoglobin facilitates the transport of carbon dioxide

Last Answer : deoxygenated haemoglobin facilitates the transport of carbon dioxide

Description : At the pH of blood 7.4, the ratio between the carbonic acid and bicarbonate fractions is (A) 1 : 10 (B) 1 : 20 (C) 1 : 30 (D) 1 : 40

Last Answer : Answer : B

Description : Respiratory alkalosis is caused by (A) An increase in carbonic acid fraction (B) A decrease in bicarbonic fraction (C) A decrease in the carbonic acid fraction (D) An increase in bicarbonate fraction

Last Answer : Answer : C

Description : Respiratory acidosis is caused by (A) Increase in carbonic acid relative to bicarbonate (B) Decrease in bicarbonate fraction (C) Increase in bicarbonate fraction (E) Decrease in the carbonic acid fraction

Last Answer : Answer : A

Description : The saliva pH is approximately 6.8. It is thus a slightly acid pH. Saliva lubricates the food bolus and initiates the enzymatic extracellular digestion of food. It also works as a buffer for the ... 's milk and in the mucosae of the intestine and airways) that protect the organism against pathogens.

Last Answer : What is the salivary digestive enzyme? Which type of food does it digest and into which smaller molecules does it transform the food?

Description : pKa of dihydrogen phosphate is (A) 5.8 (B) 6.1 (C) 6.8 (D) 7.1

Last Answer : Answer : C

Description : The principal cation in extracellular fluid is (A) Sodium (B) Potassium (C) Calcium (D) Magnesium

Last Answer : Answer : A

Description : Sodium tri poly phosphate (STPP) is manufactured by reaction of phosphoric acid with sodium (A) Carbonate (B) Phosphate (C) Bicarbonate (D) Silicate

Last Answer : (A) Carbonat

Description : Anion gap is the difference in the plasma concentrations of (A) (Chloride) – (Bicarbonate) (B) (Sodium) – (Chloride) (C) (Sodium + Potassium) – (Chloride + Bicarbonate) (D) (Sum of cations) – (Sum of anions)

Last Answer : Answer : C

Description : All the following statements about renal tubular acidosis are correct except (A) Renal tubules may be unable to reabsorb bicarbonate (B) Renal tubules may be unable to secrete hydrogen ions (C) Plasma chloride is elevated (D) Anion gap is decreased

Last Answer : Answer : D

Description : Which of the following statements about respiratory acidosis are true? A. Compensation occurs by a shift of chloride out of the red blood cells. B. Renal compensation occurs rapidly. C. Retention of ... of respiratory acidosis. E. The ratio of bicarbonate to carbonic acid is less than 20:1.

Last Answer : Answer: CE DISCUSSION: Renal compensation for acute hypoventilation is relatively slow. Depression of the respiratory center by morphine can lead to respiratory acidosis. Renal retention of bicarbonate, ... into red cells combine to increase the ratio of bicarbonate to carbonic acid to 20:1

Description : Which of the following statements about extracellular fluid are true? A. The total extracellular fluid volume represents 40% of the body weight. B. The plasma volume constitutes one fourth ... the interstitial fluid. E. The interstitial fluid equilibrates slowly with the other body compartments.

Last Answer : Answer: B DISCUSSION: The total extracellular fluid volume represents 20% of body weight. The plasma volume is approximately 5% of body weight. Sodium is the principal cation. The ... fluid and cerebrospinal fluid, the majority of the interstitial fluid exists as a rapidly equilibrating component

Description : There are two properties of the cell necessary to maintain nonequilibrium cellular composition; the first is selectivity and the second is energy conversion. Which of the following statement(s ... transported via secondary active transport include hydrogen ions, calcium, amino acids and glucose

Last Answer : Answer: c, d The selectivity of the plasma membrane, although impressive, cannot account for the nonequilibrium composition of living cells. A cell can be maintained in a nonequilibrium state only by ... to drive the transport of a second species such as protons, calcium, amino acids, or glucose

Description : During compensation of respiratory alkalosis, all the following changes occur except (A) Decreased secretion of hydrogen ions by renal tubules (B) Increased excretion of sodium in urine (C) Increased excretion of bicarbonate in urine (D) Increased excretion of ammonia in urine

Last Answer : Answer : D

Description : Which of the following electrolytes is a major cation in body fluid? a) Potassium Potassium is a major cation that affects cardiac muscle functioning. b) Chloride Chloride is an anion. c) Bicarbonate Bicarbonate is an anion. d) Phosphate Phosphate is an anion.

Last Answer : a) Potassium Potassium is a major cation that affects cardiac muscle functioning.

Description : Human urine is usually acidic because (a) potassium and sodium exchange generates acidity (b) hydrogen ions are actively secreted into the filtrate (c) the sodium transporter exchanges one hydrogen ion for each sodium ion, in peritubular capillaries (d) excreted plasma proteins are acidic.

Last Answer : (b) hydrogen ions are actively secreted into the filtrate

Description : Which of the following statement(s) is/are true concerning the microvascular and cellular response to shock? a. Osmodically induced mobilization of intracellular fluid is the initial ... d. Abnormal intracellular calcium homeostasis may contribute to the cellular dysfunction of shock

Last Answer : Answer: c, d Moderate hypovolemia results in a relatively rapid spontaneous restitution of intravascular volume through expansion of the plasma space. This plasma expansion by ... potassium pump. Cellular dysfunction also appears to be related to abnormal intracellular calcium homeostasis

Description : Which of the following electrolytes is a major anion in body fluid? a) Chloride Chloride is a major anion found in extracellular fluid. b) Potassium Potassium is a cation. c) Sodium Sodium is a cation. d) Calcium Calcium is a cation.

Last Answer : a) Chloride Chloride is a major anion found in extracellular fluid.

Description : Compared with intracellular fluid, extracellular fluid has, a. a greater osmolarity b. a higher protein concentration c. a lower chloride ion concentration d. a lower hydrogen ion concentration

Last Answer : a lower hydrogen ion concentration

Description : An example of competitive inhibition of an enzyme is the inhibition of a. Succinic dehydrogenase by malonic acid b. Cytochrome oxidase by cyanide c. Hexokinase by glucose-6-phosphate d. Carbonic anhydrase by carbon dioxide

Last Answer : Ans: A

Description : You are required to draw blood from a patient and to keep it in a test tube for analysis of blood corpuscles and plasma. You are also provided with the following four types of test tubes ... bicarbonate (b) Chilled test tube (c) Test tube containing heparin (d) Test tube containing sodium oxalate

Last Answer : (a) Test tube containing calcium bicarbonate

Description : The highest concentration of proteins is present in (A) Plasma (B) Interstitial fluid (C) Interstitial fluid (D) Transcellular fluid

Last Answer : Answer : C

Description : Oncotic pressure of plasma is due to (A) Proteins (B) Chloride (C) Sodium (D) All of these

Last Answer : Answer : A

Description : Osmotically active substances in plasma are (A) Sodium (B) Chloride (C) Proteins (D) All of these

Last Answer : Answer : D

Description : The percentage of calcium present in extracellular fluid is (A) 1 (B) 5 (C) 10 (D) 50

Last Answer : Answer : A

Description : In primary dehydration (A) Intracellular fluid volume is reduced (B) Intracellular fluid volume remains normal (C) Extracellular fluid volume is much reduced (D) Extracellular fluid volume is much increased

Last Answer : Answer : A

Description : The % of ‘K’ in Extracellular fluid is about (A) 1% (B) 2 to 3% (C) 10% (D) 15%

Last Answer : Answer : A

Description : An extracellular fluid having a higher concentration of chloride than serum is (A) Bile (B) Sweat (C) CSF (D) Pancreatic juice

Last Answer : Answer : C

Description : Which of the following statement is correct about membrane cholesterol? (A) The hydroxyl group is located near the centre of the lipid layer (B) Most of the cholesterol is in the form ... forms a rigid, planar structure (D) The hydrocarbon chain of cholesterol projects into the extracellular fluid

Last Answer : C

Description : Dolichol phosphate is A- a complex lipid involved in docking vesicles with the plasma membrane B- the anchor on which sugars assemble before transfer to proteins C- a chaperone used in protein folding D- a product of phospholipase C activation

Last Answer : the anchor on which sugars assemble before transfer to proteins

Description : Thiazide diuretics inhibit (A) Carbonic anhydrase (B) Aldosterone secretion (C) ADH secretion (D) Sodium reabsorption in distal tubules

Last Answer : Answer : D

Description : The normal ratio between the alkaline phosphate and acid phosphate in plasma is (A) 2 : 1 (B) 1 : 4 (C) 20 : 1 (D) 4 : 1

Last Answer : Answer : D

Description : Anion gap of plasma can be due to the presence of all the following except (A) Bicarbonate (B) Lactate (C) Pyruvate (D) Citrate

Last Answer : Answer : A

Description : The primary event in respiratory alkalosis is (A) Rise in pH (B) Decrease in pCO2 (C) Increase in plasma bicarbonate (D) Decrease in plasma chloride

Last Answer : Answer : B

Description : The initial event in respiratory acidosis is (A) Decrease in pH (B) Increase in pCO2 (C) Increase in plasma bicarbonate (D) Decrease in plasma bicarbonate

Last Answer : Answer : B

Description : Plasma bicarbonate is increased in (A) Respiratory alkalosis (B) Metabolic alkalosis (C) Respiratory acidosis (D) Metabolic acidosis

Last Answer : Answer : B

Description : Plasma bicarbonate is decreased in (A) Respiratory alkalosis (B) Respiratory acidosis (C) Metabolic alkalosis (D) Metabolic acidosis

Last Answer : Answer : D