Description : Thiazide diuretics enhance K+ elimination in urine primarily by: A. Inhibiting proximal tubular K+ reabsorption B. Inhibiting Na+ K+-2Cl- cotransport in the ascending limb of loop of Henle C ... in the distal tubular fluid to exchange with interstitial K+ D. Potentiating the action of aldosterone
Last Answer : C. Increasing the availability of Na+ in the distal tubular fluid to exchange with interstitial K
Description : Aldosterone enhances Na+ reabsorption in renal tubules by: A. Stimulating carbonic anhydrase B. Activating Na+ K+ ATPase C. Inducing the synthesis of Na+ K+ ATPase D. Inducing renal prostaglandin synthesis
Last Answer : C. Inducing the synthesis of Na+ K+ ATPase
Description : The following are true about aldosterone: a. it is secreted by the adrenal medulla b. its secretion is stimulated by decreased blood volume c. it stimulates active reabsorption of sodium in the distal renal tubules. d. it causes increased secretion of potassium by the distal renal tubules.
Last Answer : it causes increased secretion of potassium by the distal renal tubules.
Description : Inhibition of carbonic anhydrase results in (a) Abolition of NaHCO3 reabsorption in proximal tubule (b) Enhanced of NaHCO3 reabsorption in proximal tubule (c) Enhanced NAHCO3 secretion in distal tubule (d) None of the above
Last Answer : Ans: A
Description : Which of the following would help in prevention of diuresis? (a) More water reabsorption due to undersecretion of ADH. (b) Reabsorption of Na+ and water from renal tubules due to ... Atrial natriuretic factor causes vasoconstriction. (d) Decrease in secretion of renin by JG cells. (NEE
Last Answer : (b) Reabsorption of Na+ and water from renal tubules due to aldosterone.
Description : Aldosterone increases reabsorption of sodium in (A) Proximal convoluted tubules (B) Ascending limb of loop of Henle (C) Descending limb of loop of Henle (D) Distal convoluted tubules
Last Answer : Answer : D
Description : All the following diuretics inhibit the carbonic anhydrase except (A) Acetazolamide (B) Bumetanide (C) Furosemide (D) Ethacrynic acid
Description : Antidiuretic hormone (A) Is secreted by hypothalamus (B) Secretion is increased when osmolality of plasma decreases (C) Increases obligatory reabsorption of water (D) Acts on distal convoluted tubules and collecting ducts
Description : Urine volume is increased with: a. carbonic anhydrase inhibitors b. hyperglycaemia c. increased aldosterone secretion d. damage to the posterior pituitary
Last Answer : damage to the posterior pituitary
Description : Antidiuretic hormone (ADH) - (1) inhibits the secretion of growth hormone by the pituitary (2) inhibits the rate of heart beat (3) causes the muscular walls of the arterioles to contract that simulates the reabsorption of water from the kidney tubules (4) causes an increase in the blood pressure
Last Answer : (3) causes the muscular walls of the arterioles to contract that simulates the reabsorption of water from the kidney tubules
Description : Furosemide inhibits reabsorption of sodium and chloride in (A) Proximal convoluted tubules (B) Loop of Henle (C) Distal convoluted tubules (D) Collecting ducts
Last Answer : Answer : B
Description : Nonsteroidal antiinflammatory drugs reduce the diuretic action of furosemide by: A. Preventing prostaglandin mediated intrarenal haemodynamic actions B. Blocking the action in ascending limb of loop ... C. Enhancing salt and water reabsorption in distal tubule D. Increasing aldosterone secretion
Last Answer : A. Preventing prostaglandin mediated intrarenal haemodynamic actions
Description : Which of the following causes an increase in sodium reabsorption in the distal convoluted tubule? (a) Increase in aldosterone levels (b) Increase in antidiuretic hormone levels (c) Decrease in aldosterone levels (d) Decrease in antidiuretic hormone levels
Last Answer : (a) Increase in aldosterone levels
Description : Identify one of the canbonic anhydrase inhibitor that inhibit only luminal carbonic anhydrase enzyme. (A) Methazolamide (B) Acetazolamide (C) Dichlorphenamide(D) Benzolamide
Description : Obligatory reabsorption of water (A) Is about 50% of the total tubular reabsorption of water (B) Is increased by antidiuretic hormone (C) Occurs in distal convoluted tubules (D) Is secondary to reabsorption of solutes
Description : The following occur in the proximal tubules of the nephron: a. reabsorption of all glucose b. reabsorption of most water c. secretion of bicarbonate d. active reabsorption of sodium
Last Answer : active reabsorption of sodium
Description : Diabetes insipidus results from (A) Decreased insulin secretion (B) Decreased ADH secretion (C) Decreased aldosterone secretion (D) Unresponsiveness of osmoreceptors
Description : An increase in the osmolality of extracellular compartment will (A) Inhibit ADH secretion (B) Stimulate ADH secretion (C) Cause no change in ADH secretion (D) Stimulate the volume and osmoreceptor and inhibit ADH secretion
Description : Water reabsorption in the distal parts of kidney tubules is regulated by
Last Answer : Water reabsorption in the distal parts of kidney tubules is regulated by A. STH B. TSH C. ADH D. MSH
Description : Match the source gland with its respective hormone and function and select the correct option. Source Hormone Function gland (a) Anterior Oxytocin Contraction of uterus pituitary muscles during ... (c) Corpus Estrogen Supports pregnancy luteum (d) Thyroid Thyroxine Regulates blood calcium level
Last Answer : (b) Posterior Vasopressin Stimulates pituitary reabsorption of water in the distal tubules in the nephron
Description : Assertion `:-` Angiotensin II is a powerful vasconstrictor Reason `:-` Aldosterone causes reabsorption of `Na^(+)` and water from distal parts of the
Last Answer : Assertion `:-` Angiotensin II is a powerful vasconstrictor Reason `:-` Aldosterone causes reabsorption of ... D. If both Assertion & Reason are false.
Description : The following diuretic acts on the luminal membrane of distal tubule and collecting ducts to inhibit electrogenic Na+ reabsorption so that K+ excretion is diminished and bicarbonate excretion is enhanced: A. Xipamide B. Isosorbide C. Triamterene D. Spironolactone
Last Answer : C. Triamterene
Description : Increased reabsorption of water from the kidney is the major consequence of the secretion of the hormone? (A) Cortisol (B) Insulin (C) Vasopressin (D) Aldosterone
Last Answer : Answer : C
Description : Anti-diuretic diuretic hormone (ADH) a. is synthesized by the posterior lobe of the pituitary gland b. is released by neurosecretion c. its secretion is increased by a low plasma osmolarity d. increases the permeability of the distal convoluted tubule
Last Answer : is released by neurosecretion
Description : A 55-year-old male undergoes a total abdominal colectomy. Which of the following statement(s) is/are true concerning the hormonal response to the surgical procedure? a. Adrenocorticotropic ... in serum insulin and a fall in glucagon accelerate hepatic glucose production and maintain gluconeogenesis
Last Answer : Answer: a, c One of the earliest consequence of a surgical procedure is the rise in levels of circulating cortisol that occur in response to a sudden outpouring of ACTH ... hepatic glucose production, and, with other hormones (epinephrine and glucocorticoids), gluconeogenesis is maintained
Description : ADH resposible for the reabsorption of water and reduction of urine secretion is synthesized by
Last Answer : ADH resposible for the reabsorption of water and reduction of urine secretion is synthesized by ... C. Anterior ptiuitary gland D. Hypothalamus
Description : Secretion of K+ in the late distal tubule and collecting ducts of kidney depends on: A. Intracellular K+ content B. Unabsorbed Na+ load presented to the distal segment C. Aldosterone level D. All of the above
Last Answer : D. All of the above
Description : True statements about aldosterone include: a. secretion is mainly under the control of adrenocorticotrophic (ACTH) hormone secretion b. increases hepatic gluconeogenesis c. its secretion is stimulated by angiotensin d. in the kidney, mainly acts on the proximal convoluted tubules
Last Answer : its secretion is stimulated by angiotensin
Description : The most important effect of aldosterone is to (A) Increase the rate of tubular reabsorption of sodium (B) Decrease the rate of tubular reabsorption of potassium (C) Decrease the reabsorption of chloride (D) Decrease the renal reabsorption of sodium
Last Answer : Answer : A
Description : Metabolic alkalosis can occur in (A) Severe diarrhoea (B) Renal failure (C) Recurrent vomiting (D) Excessive use of carbonic anhydrase inhibitors
Description : Zn is present as prosthetic group in this enzyme: (A) Carbonic anhydrase (B) Carboxy peptidase (C) Lactate dehydrogenase (D) All of these
Description : Zinc is a constituent of the enzyme: (A) Succinate dehydrogenase (B) Carbonic anhydrase (C) Mitochondrial superoxide dismutase (D) Aldolase
Description : Carbonic anhydrase enzyme has maximum turn over number (36 million). Minimum turn over number for an enzyme: (A) DNA polymerase (B) Lysozyme (C) Penicillase (D) Lactase dehydrogenase
Description : All of the following are iron-containing enzymes except (A) Carbonic anhydrase (B) Catalase (C) Peroxidase (D) Cytochrome oxidase
Description : All of the following are zinc-containing enzymes except (A) Acid Phosphatase (B) Alkaline Phosphatase (C) Carbonic anhydrase (D) RNA polymerase
Description : Carbonic anhydrase is competitively inhibited by (A) Allopurinol (B) Acetazolamide (C) Aminopterin (D) Neostigmine
Description : Physostigmine is a competitive inhibitor of (A) Xanthine oxidase (B) Cholinesterase (C) Carbonic anhydrase (D) Monoamine oxidase
Description : Carbonic anhydrase is an example of (A) Lipoprotein (B) Phosphoprotein (C) Metalloprotein (D) Chromoprotein
Description : Which of the following causes an increase in sodium reabsorption in the distal convoluted tubule
Last Answer : Which of the following causes an increase in sodium reabsorption in the distal convoluted tubule ... levels D. Decrease in antidiuretic hormone levels
Description : The part of nephron involved in active reabsorption of sodium is (a) distal convoluted tubule (b) proximal convoluted tubule (c) Bowman’s capsule (d) descending limb of Henle’s loop.
Last Answer : (b) proximal convoluted tubule
Description : During compensation of respiratory alkalosis, all the following changes occur except (A) Decreased secretion of hydrogen ions by renal tubules (B) Increased excretion of sodium in urine (C) Increased excretion of bicarbonate in urine (D) Increased excretion of ammonia in urine
Description : One of the potent st imu lators of aldosterone secretion is (A) Increased sodium concentration (B) Decreased potassium concentration (C) Increased potassium concentration (D) Increased ECF volume
Description : Aldosterone: a. increases mRNA synthesis b. deficiency results in hypotension c. increases sodium reabsorption from sweat d. all above
Last Answer : all above
Description : Which one of the following is lest likely to be useful in the therapy of hypercalcemia? (a) Calcitonin (b) Glucocorticoids (c) Plicamycin (d) Parenteral infusion of phosphate (e) Thiazide diuretics
Last Answer : Ans: E
Description : Which of the following categories of medications may result in seizure activity if withdrawn suddenly? a) Tranquilizers Abrupt withdrawal of tranquilizers may result in anxiety, tension, ... may cause excessive respiratory depression during anesthesia due to an associated electrolyte imbalance.
Last Answer : a) Tranquilizers Abrupt withdrawal of tranquilizers may result in anxiety, tension, and even seizures if withdrawn suddenly.
Description : Combined tablets of thiazide or high ceiling diuretics with potassium chloride are not recommended because: A. Potassium absorbed while diuresis is occurring is largely excreted out B. Potassium administered concurrently ... is likely to cause gut ulceration D. Both A' and C' are correct
Last Answer : D. Both ‘A’ and ‘C’ are correct
Description : Individual drugs of thiazide and related class of diuretics differ markedly from each other in the following respect? A. Diuretic efficacy B. Diuretic potency C. Side effects D. Propensity to cause hyperkalemia
Last Answer : B. Diuretic potency
Description : The primary site of action of thiazide diuretics is: A. Proximal tubule B. Ascending limb of loop of Henle C. Cortical diluting segment D. Collecting ducts
Last Answer : C. Cortical diluting segment
Description : Choose the correct statement about thiazide diuretics: A. They act in the proximal convoluted tubule B. They are uricosuric C. They augment corticomedullary osmotic gradient D. They induce diuresis in acidosis as well as alkalosis
Last Answer : D. They induce diuresis in acidosis as well as alkalosis