Normal anatomyThe gastrointestinal tract starts at the mouth, which leads to the esophagus, stomach, small intestine, colon, and finally, the rectum and anus. The GI tract is a long, hollow, muscular tube through which food passes and nutrients are absorbed.IndicationBleeding from the GI tract is a common medical problem. Patients usually notice either dark red blood or bright red blood in their stool.Ulcers of the stomach and duodenum are common causes of bleeding from the upper GI tract. Bleeding can also occur in the lower GI tract (colon). Diverticular bleeding is a common cause of lower GI bleeding.Procedure, part 1The first step in the treatment of GI bleeding is to locate the source of the bleeding. Patients who have lost significant amounts of blood are transfused with blood.Next, an endoscopy is used to locate the source of the bleeding. Upper endoscopy is generally performed first, and if no bleeding source is located, then lower endoscopy is performed. During an endoscopy, the patient is usually sedated but awake.Procedure, part 2In many cases, GI bleeding will stop on its own, with no treatment. In other cases, treatment can be provided with the endoscope, most often in the form of cautery (electrocoagulation) of the site of bleeding.Procedure, part 3If the bleeding cannot be stopped using the endoscope, surgery may be required. The bleeding segment of intestine or stomach is removed. However, most cases of GI bleeding are managed succesfully with endsocopy.Reviewed ByReview Date: 01/31/2011David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and George F. Longstreth, MD, Department of Gastroenterology, Kaiser Permanente Medical Care Program San Diego, California. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.