Description : The following is true in the treatment of epilepsy except: A. The choice of drug depends on the cause of epilepsy and not on the seizure type B. Treatment should be instituted as early as possible ... to response D. Withdrawal of drug can be attempted if no seizures have occurred for 3-5 years
Last Answer : A. The choice of drug depends on the cause of epilepsy and not on the seizure type
Description : Define armature reaction in an alternator. Explain the effect of armature reaction at various P.F. of loads of alternator.
Last Answer : Armature Reaction: The effect of armature flux on main flux is called as armature reaction. Armature Reaction at Various Power Factors: When armature is loaded, the armature flux modifies ... lagging p.f. For capacitive loads the effect of flux is partly distorting and partly strengthening.
Description : Clobazam is a benzodiazepine used as: A. Hypnotic B. Muscle relaxant C. Anxiolytic D. Antiepileptic
Last Answer : D. Antiepileptic
Description : Barbiturates with substitution at the following position possess acceptable hypnotic activity : (A) 1,3-Disubstitution (B) 5,5-Disubstitution (C) 1,5-Disubstitution (D) 3,3-Disubstitution
Last Answer : (B) 5,5-Disubstitution
Description : Which of the following anticholinergic drugs is primarily used in preanaesthetic medication and during surgery (a) Glycopyrrolate (b) Pipenzolate methyl bromide (c) Isopropamide (d) Dicyclomine
Last Answer : Ans: A
Description : Which of the following anticholinergic drugs is primarily used in preanaesthetic medication and during surgery: A. Glycopyrrolate B. Pipenzolate methyl bromide C. Isopropamide D. Dicyclomine
Last Answer : A. Glycopyrrolate
Description : The following drug is routinely used in preanaesthetic medication for prolonged operations: A. Atropine B. Morphine C. Promethazine D. Ranitidine
Last Answer : D. Ranitidine
Description : Use of glycopyrrolate in preanaesthetic medication serves the following purposes except: A. Prevents respiratory secretions during anaesthesia B. Guards against reflex vagal bradycardia during ... Produces amnesia for perioperative events D. Reduces the probability of occurrence of laryngospasm
Last Answer : C. Produces amnesia for perioperative events
Description : Use of morphine in preanaesthetic medication: A. Is routine except in the presence of contraindications B. Is restricted to patients being anaesthetised with ether C. Should be made only in combination with atropine D. Is restricted mostly to patients in pain preoperativel
Last Answer : D. Is restricted mostly to patients in pain preoperatively
Description : Pyritinol (pyrithioxine) is used as: A. Analeptic drug B. Cognition enhancing drug C. Antiepileptic drug
Last Answer : B. Cognition enhancing dru
Description : Risk of neural tube defect in the offspring can be minimised in pregnant women receiving antiepileptic drugs by supplemental therapy with: A. Folic acid B. Vitamin A C. Vitamin E D. Pyridoxine
Last Answer : B. Vitamin A
Description : Select the factor which indicates that withdrawal of the successfully used antiepileptic medication is likely to result in recurrence of seizures: A. Childhood epilepsy B. Partial seizures C. Treatment started soon after seizure onset D. Absence of EEG abnormality
Last Answer : B. Partial seizures
Description : A combination of two or more antiepileptic drugs is used: A. Routinely in all types of epilepsy B. In all cases of complex partial seizures C. In all cases of secondarily generalized seizures D. Only when monotherapy with first/second choice drugs fails
Last Answer : D. Only when monotherapy with first/second choice drugs fails
Description : The following is true of topiramate except: A. It is a broad spectrum antiepileptic drug B. It inhibits the enzyme carbonic anhydrase C. It is used as add-on therapy in refractory partial seizures D. It is not effective in generalized tonic-clonic seizures
Last Answer : D. It is not effective in generalized tonic-clonic seizures
Description : Select the antiepileptic drug that in addition is a preferred treatment for post herpetic neuralgia and pain due to diabetic neuropathy: A. Carbamazepine B. Gabapentin C. Lamotrigine D. Primidone
Last Answer : B. Gabapentin
Description : Choose the correct statement about lamotrigine: A. It is a dopaminergic agonist used in parkinsonism B. It acts by blocking NMDA-type of glutamate receptors C. It is a broad spectrum antiepileptic drug D. It suppresses tonic-clonic seizures, but worsens absence seizures
Last Answer : C. It is a broad spectrum antiepileptic drug
Description : Select the drug having a narrow spectrum antiepileptic activity restricted to absence seizures: A. Lamotrigine B. Ethosuccimide C. Sodium valproate D. Primidone
Last Answer : . Ethosuccimide
Description : he antiepileptic drug which suppresses maximal electroshock as well as kindled seizures, raises pentylenetetrazol threshold and is effective in both generalized tonic-clonic as well as absence seizures is: A. Phenytoin B. Carbamazepine C. Sodium valproate D. Ethosuximide
Last Answer : C. Sodium valproate
Description : The following antiepileptic drug raises pentylene tetrazol seizure threshold but does not modify maximal electroshock seizures: A. Ethosuximide B. Carbamazepine C. Primidone D. Phenobarbitone
Last Answer : A. Ethosuximide
Description : The following antiepileptic drug is likely to cause hyponatremia as a side effect, especially in elderly patients: A. Primidone B. Carbamazepine C. Phenytoin D. Sodium valproate
Last Answer : B. Carbamazepine
Description : Select the antiepileptic drug that is effective in manicdepressive illness as well: A. Ethosuccimide B. Primidone C. Phenobarbitone D. Carbamazepine
Last Answer : D. Carbamazepine
Description : The following antiepileptic drug is most likely to impair learning and memory, and produce behavioral abnormalities in children: A. Valproic acid B. Phenobarbitone C. Phenytoin D. Ethosuximide
Last Answer : B. Phenobarbitone
Description : The acid that can be used as a hypnotic is (a) tartaric acid (b) benzoic acid (c) barbituric acid (d) acetic acid
Last Answer : Ans:(c)
Description : The general principles in the use of hypnotics include the following except: A. A hypnotic may be used intermittently for upto 2-3 weeks in short-term insomnia due to emotional stress B ... sleep apnoea D. A hypnotic with slow elimination is preferred in patients with early morning awakening
Last Answer : B. In patients with chronic insomnia a hypnotic should be used regularl
Description : Zolpidem differs from diazepam in that: A. It is safer in overdose than diazepam B. Its hypnotic action shows little fading on repeated nightly use C. It causes more marked suppression of REM sleep D. It has more potent muscle relaxant action
Last Answer : B. Its hypnotic action shows little fading on repeated nightly use
Description : Choose the drug that has been found to be more selective for the ω1 subtype of BZD receptor, and produces hypnotic action but little antianxiety, muscle relaxant or anticonvulsant actions: A. Zopiclone B. Zolpidem C. Flumazenil D. Melatonin
Last Answer : B. Zolpidem
Description : Which of the following statements is not true of zopiclone: A. It is a nonbenzodiazepine hypnotic with efficacy and safety similar to benzodiazepines B. It does not produce rebound sleep disturbances ... act by potentiating GABA D. It is used to wean off insomniacs from regular benzodiazepine use
Last Answer : C. It does not act by potentiating GABA
Description : The following is a very potent and short acting benzodiazepine whose use as hypnotic has been noted to cause psychiatric disturbances in some cases: A. Flurazepam B. Nitrazepam C. Temazepam D. Triazolam
Last Answer : D. Triazolam
Description : At a single hypnotic dose, the pharmacokinetics of diazepam is characterised by: A. Slow elimination and little redistribution B. Slow elimination with marked redistribution C. Rapid elimination and marked redistribution D. Ultra rapid elimination
Last Answer : B. Slow elimination with marked redistribution
Description : Hypnotic dose of diazepam produces the following action: A. Tachycardia B. Constipation C. Hyperalgesia D. Decreased nocturnal gastric secretion
Last Answer : D. Decreased nocturnal gastric secretion
Description : Select the correct statement about benzodiazepines (BZDs): A. All BZDs facilitate GABA mediated Cl¯ influx into neurones B. Different BZDs exert the same degrees of hypnotic, anxiolytic and anticonvulsant ... at all neuronal sites D. The muscle relaxant action of BZDs is not blocked by flumazenil
Last Answer : A. All BZDs facilitate GABA mediated Cl¯ influx into neurones
Description : Hypnotic benzodiazepines increase the period of time spent in the following stage of sleep: A. Stage II B. Stage III C. Stage IV D. REM stage
Last Answer : A. Stage II
Description : Effect of alcohol on sleep has the following feature: A. It is a dependable hypnotic but is not prescribed because of abuse potential B. It consistently improves the quality of sleep C. It can disorganise sleep architecture D. It suppresses sleep apnoea
Last Answer : C. It can disorganise sleep architecture
Description : Sustained/controlled release oral dosage form is appropriate for the following type of drug: A. An antiarthritic with a plasma half life of 24 hr B. A sleep inducing hypnotic with a plasma half life of ... 3 hours D. An analgesic with a plasma half life of 6 hours used for relief of casual headache
Last Answer : C. An antihypertensive with a plasma half life of 3 hours
Last Answer : Microsomal enzyme induction has one of the following features: A. Takes about one week to develop B. Results in increased affinity of the enzyme for the substrate C. It is irreversible D. Can be used to treat acute drug poisonings
Description : How do barbiturates differ from heroin?
Last Answer : Barbiturates are a class of drugs derived from barbituric acidthat act as depressants to the central nervous system. They havesedative and addictive effects.Heroin is an opioid drug made from ... made from.Barbiturates are made form barbituric acid and heroin is made fromopium poppy plants.
Description : In combination with alcohol barbiturates do not have the potential for severe impairment true or false?
Last Answer : That is false. When combined the effects are MUCH greater thanthe effect of each by itself.
Description : What are barbiturates ? To which class of drugs do they belong ?
Last Answer : Ans. 5, 5-derivatives of barbituric acid are called barbiturates. They belong to the class of tranquilizers. They also act as sleep producing agents. Eg. Luminal, Veronal.
Description : .Which of the following is an opiate narcotic? (a) Amphetamines (b) LSD (c) Barbiturates (d) Morphine
Last Answer : (d) Morphine
Description : Which one of the following is the correct statement regarding the particular psychotropic drug specified? (a) Morphine leads to delusions and disturbed emotions. (b) Barbiturates cause ... thought perceptions and hallucinations. (d) Opium stimulates nervous system and causes hallucinations.
Last Answer : (c) Hashish causes after thought perceptions and hallucinations
Description : Select the correct statement from the ones given below. (a) Barbiturates, when given to criminals, make them tell the truth. (b) Morphine is often given to persons, who have undergone surgery, ... pressure and heart rate. (d) Cocaine is given to patients after surgery as it stimulates recovery.
Last Answer : (b) Morphine is often given to persons, who have undergone surgery, as a pain killer.
Description : Reflex activity decrease under the influence of a. anesthetic b. barbiturates c. catamine d. all
Last Answer : all
Description : The common structural feature amongst the three categories of anticonvulsant drugs barbiturates, succinimides and hydantoins is (A) ureide (B) imidazolidinone (C) dihydropyrimidine (D) tetrahydropyrimidine
Last Answer : (A) ureide
Description : A patient with a history of angina suffers an attack while in the dental chair. Prompt relief can be anticipated in MOST instances from: A. Oral administration of short acting ... epinephrine D. Sublingual administration of glyceryl tri-nitrate E. Putting the patient in upright position
Last Answer : D. Sublingual administration of glyceryl tri-nitrate
Description : Drugs contraindicated with Monoaminoxidase Inhibitors (MAOI):VERY IMP AND CONTROVERSIAL QUESTION A. Barbiturates B. Pethidine C. Local Anaesthesia with felypressin D. Narcotic analgetics E. Salicylic acid
Last Answer : B. Pethidine
Description : Select the correct statement about flumazenil: A. It is a CNS stimulant used as an antidote for benzodiazepine poisoning B. It is a CNS depressant but blocks the action of diazepam C. It has ... of its own but blocks the depressant effect of diazepam as well as stimulant effect of beta carbolines
Last Answer : D. It has no CNS effect of its own but blocks the depressant effect of diazepam as well as stimulant effect of beta carbolines
Description : Benzodiazepines differ from barbiturates in the following aspects except: A. They have a steeper dose response curve B. They have higher therapeutic index C. They have lower abuse liability D. They do not induce microsomal drug metabolizing enzymes
Last Answer : A. They have a steeper dose response curve
Description : The mechanism of action of barbiturates differs from that of benzodiazepines in that they: A. Do not affect the GABA-benzodiazepine receptor-chloride channel complex B. Act as inverse agonists at the ... without affecting its life time D. Have both GABA-facilitatory as well as GABA-mimetic actions
Last Answer : D. Have both GABA-facilitatory as well as GABA-mimetic actions