The following statement about lithium is not correct: A. It has a sedative action in normal individuals B. It controls mania, but takes 1–2 weeks to produce the effect C. It has prophylactic effect in recurrent unipolar depression D. It can be combined with tricyclic antidepressants for refractory cases of major depression

The following statement about lithium is not correct:
A. It has a sedative action in normal individuals
B. It controls mania, but takes 1–2 weeks to
produce the effect
C. It has prophylactic effect in recurrent
unipolar depression
D. It can be combined with tricyclic antidepressants for refractory cases of major depression
by

1 Answer

Answer :

A. It has a sedative action in normal individuals
by

Related questions

The distinctive features of fluoxetine compared to the typical tricyclic antidepressants include the following except: A. It is less likely to produce cardiac arrhythmias in overdose B. It infrequently produces sedative and anticholinergic side effects C. It can elevate mood of apparently nondepressed patients suffering from chronic somatic illness D. It does not block neuronal uptake of biogenic amines

Description : The distinctive features of fluoxetine compared to the typical tricyclic antidepressants include the following except: A. It is less likely to produce cardiac arrhythmias in overdose B. It infrequently ... suffering from chronic somatic illness D. It does not block neuronal uptake of biogenic amines

Last Answer : D. It does not block neuronal uptake of biogenic amines

Indications of tricyclic antidepressants include the following except: A. Attention deficit-hyperactive disorder in children B. Mania C. Prophylaxis of migraine D. Panic disorder

Description : Indications of tricyclic antidepressants include the following except: A. Attention deficit-hyperactive disorder in children B. Mania C. Prophylaxis of migraine D. Panic disorder

Last Answer : B. Mania

Choose the correct statement about nonsteroidal antiinflammatory drugs (NSAIDs): A. NSAIDs attenuate hypoglycaemic action of sulfonylureas B. NSAIDs potentiate antihypertensive action of ACE inhibitors C. Serum lithium levels are lowered by concurrent administration of NSAIDs D. Combined therapy with prednisolone and NSAIDs carries higher risk of gastric bleeding

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Last Answer : D. Combined therapy with prednisolone and NSAIDs carries higher risk of gastric bleeding

The following drug can be used as an alternative to lithium in mania and bipolar illness: A. Carbamazepine B. Carisoprodol C. Clomipramine D. Diethyl carbamazine

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The principal action common to all class I antiarrhythmic drugs is: A. Na+ channel blockade B. K+ channel opening C. Depression of impulse conduction D. Prolongation of effective refractory period

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Last Answer : A. Na+ channel blockade

Select the drug which is a causal prophylactic for both falciparum and vivax malaria but is not used as prophylactic on mass scale due to risk of severe reaction in some individuals: A. Mefloquine B. Amodiaquine C. Primaquine D. Pyrimethamine

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The following drug/drugs does/do not produce any overt CNS effect in normal individuals but exert(s) clear cut therapeutic effect at the same dose in the presence of a specific neurological/psychiatric disorder: A. Chlorpromazine B. Levodopa C. Imipramine D. All of the above

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Last Answer : B. Levodopa

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Choose the correct statement about amiloride: A. It antagonises the action of aldosterone B. It can be used to treat lithium induced diabetes insipidus C. It increases calcium loss in urine D. It is dose to dose less potent than triamterene

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Tolerance is generally not acquired to: A. Antisecretory action of atropine B. Sedative action of chlorpromazine C. Emetic action of levodopa D. Vasodilator action of nitrates

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Choose the correct statement about iron therapy: A. Haemoglobin response to intramuscular iron is faster than with oral iron therapy B. Iron must be given orally except in pernicious anaemia C. Prophylactic iron therapy must be given during pregnancy D. Infants on breastfeeding do not require medicinal iron

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A patient of endogenous depression was put on imipramine therapy. After what interval the therapeutic effect is likely to manifest: A. Three days B. One week C. Three weeks D. Three months

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Methysergide has lost popularity as a prophylactic drug for migraine because of its: A. Poor efficacy B. Potential to cause visceral fibrosis C. Oxytocic action D. Potential to aggravate ischaemic heart disease

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The progestin used in combined oral contraceptive pill is a 19-nortestosterone derivative because: A. They have potent antiovulatory action of their own B. They do not produce any metabolic effects C. They produce fewer side effects D. They are longer acting

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Select the correct statement about combining antihypertensive drugs: A. Antihypertensive combinations should always be preferred over single drugs B. Combinations of antihypertensives with similar pattern of haemodynamic action are superior to those with dissimilar pattern C. Antihypertensives which act on different regulatory systems maintaining blood pressure should be combined D. A diuretic must be included whenever antihypertensives are combined

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Fluphenazine differs from chlorpromazine in the following respects except: A. It has higher antipsychotic efficacy B. It is less sedative C. It is less likely to precipitate seizures in epileptics D. It causes more prominent extrapyramidal side effect

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The following statement is not true of carbamazepine: A. It generates an active metabolite B. Its plasma half life decreases to nearly half of the original value after chronic use C. It is being used in mania D. It is not effective in complex partial seizures

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The following is true of selegiline: A. It does not exert antiparkinsonian action unless combined with levodopa B. It overcomes the ‘on-off ’ effect in levodopa treated advanced parkinsonian patients C. It retards the progression of Parkinson's disease D. At doses used in parkinsonism it does not interfere with peripheral metabolism of dietary amines

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Quinidine has the following action on electrophysiological properties of the heart except: A. Decreases automaticity of Purkinje fibres B. Abolishes after depolarizations C. Prolongs refractory period of atrial fibres D. Decreases membrane responsiveness of atrial and ventricular fibres

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The tricyclic antidepressants are also effective in the following psychiatric disorders except: A. Schizophrenia B. Obsessive-compulsive disorder C. Bulimia D. Phobic states

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Venlafaxine differs from standard tricyclic antidepressants in that it: A. Does not inhibit 5-HT reuptake B. Does not inhibit noradrenaline reuptake C. Does not have anticholinergic or antiadrenergic property D. Has lower antidepressant efficacy

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Limitations of typical tricyclic antidepressants include the following except: A. Narrow safety margin B. Low oral bioavailability C. Frequent side effects D. Long latent period for response

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The following drug/drugs should not be used to treat tricyclic antidepressant drug poisoning: A. Quinidine B. Digoxin C. Atropine D. All of the above

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The mechanisms involved in the causation of dangerous cardiac arrhythmias due to overdose of tricyclic antidepressants include the following except: A. Intraventricular conduction block B. Potentiation of noradrenaline C. Antagonism of acetylcholine D. Increased vagal tone

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The major constraint in the long term use of benzodiazepines for treatment of generalized anxiety disorder is: A. Development of tolerance to antianxiety action of the benzodiazepines B. Possibility of drug dependence C. Cardiovascular depression D. Likelyhood of overdose toxicit

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Combined tablets of thiazide or high ceiling diuretics with potassium chloride are not recommended because: A. Potassium absorbed while diuresis is occurring is largely excreted out B. Potassium administered concurrently diminishes the diuretic action C. Potassium chloride in tablet formulation is likely to cause gut ulceration D. Both ‘A’ and ‘C’ are correct

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Last Answer : D. Both ‘A’ and ‘C’ are correct

The following action of digoxin is responsible for beneficial effect in auricular fibrillation: A. Increased myocardial contractility B. Suppression of SA node C. Depression of A-V conduction D. Enhanced Purkinje fibre automaticity

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Last Answer : C. Depression of A-V conduction

What is true of acyclovir treatment of genital herpes simplex: A. Topical treatment affords symptomatic relief in primary as well as recurrent disease B. Oral therapy for 10 days affords symptomatic relief as well as prevents recurrences C. Oral therapy for 10 days affords symptomatic relief but does not prevent recurrences D. Continuous long-term topical therapy is recommended to prevent recurrences

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The following drug should be used only as clinical curative but not as prophylactic in malaria: A. Pyrimethamine + sulfadoxine B. Proguanil C. Primaquine D. Mefloquine

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A 30-year-old woman suffering from endogenous depression improved after one month of treatment with amitriptyline. How long the drug should be continued: A. 1-2 weeks B. 6-12 months C. 2-3 years D. Life long

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Last Answer : B. 6-12 months

Though bromocriptine acts directly on dopamine receptors, it is used in parkinsonism only as a supplement to levodopa because: A. It has low efficacy B. It produces marked dyskinesias C. Used alone, its effective doses produce intolerable side effects D. Its therapeutic effect takes long time to develop

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Last Answer : C. Used alone, its effective doses produce intolerable side effect

What is true of tolerance occurring in regular opium abusers: A. Tolerance develops to all actions of morphine B. No tolerance occurs to euphoric and sedative actions of morphine C. No tolerance occurs to constipating and miotic actions of morphine D. Lethal dose of morphine is not significantly increased

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The selective serotonin reuptake inhibitors have overcome the following limitation(s) of typical tricyclic antidepressants: A. Frequent anticholinergic, sedative and hypotensive side effects B. High risk of cardiac arrhythmias and seizures in overdose C. Delayed response

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Last Answer : D. It does not block neuronal uptake of biogenic amines

Of the following, choose the antidepressant having both high sedative and high anticholinergic activity: A. Imipramine B. Amitriptyline C. Fluoxetine D. Trazodone

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Of the following, choose the antidepressant having both high sedative and high anticholinergic activity: A. Imipramine B. Amitriptyline C. Fluoxetine D. Trazodone

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Last Answer : B. Amitriptyline

Which of the following is a high potency antipsychotic drug having minimal sedative and autonomic effects and no propensity to cause weight gain: A. Chlorpromazine B. Triflupromazine C. Haloperidol D. Olanzapine

Description : Which of the following is a high potency antipsychotic drug having minimal sedative and autonomic effects and no propensity to cause weight gain: A. Chlorpromazine B. Triflupromazine C. Haloperidol D. Olanzapine

Last Answer : C. Haloperido

The barbiturate having higher anticonvulsant: sedative activity ratio is: A. Pentobarbitone B. Phenobarbitone C. Butabarbitone D. Thiopentone

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Last Answer : B. Phenobarbitone

Select the correct statement about flumazenil: A. It is a CNS stimulant used as an antidote for benzodiazepine poisoning B. It is a CNS depressant but blocks the action of diazepam C. It has no CNS effect of its own but blocks the depressant effects of benzodiazepines as well as barbiturates D. It has no CNS effect of its own but blocks the depressant effect of diazepam as well as stimulant effect of beta carbolines

Description : Select the correct statement about flumazenil: A. It is a CNS stimulant used as an antidote for benzodiazepine poisoning B. It is a CNS depressant but blocks the action of diazepam C. It has ... of its own but blocks the depressant effect of diazepam as well as stimulant effect of beta carbolines

Last Answer : D. It has no CNS effect of its own but blocks the depressant effect of diazepam as well as stimulant effect of beta carbolines

What is true of docetaxel: A. It is used as a reserve drug for refractory breast and ovarian cancer B. It is a selective estrogen receptor modulator used for breast cancer C. It is effective only in estrogen receptor positive breast cancer D. Both 'B' and 'C' are correct

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Last Answer : A. It is used as a reserve drug for refractory breast and ovarian cancer

For therapeutic effect in manic depressive illness, steady-state serum lithium concentration should be maintained between: A. 0.2–0.4 mEq/L B. 0.5–0.8 mEq/L C. 1.0–1.3 mEq/L D. 1.5–2.5 mEq/L

Description : For therapeutic effect in manic depressive illness, steady-state serum lithium concentration should be maintained between: A. 0.2–0.4 mEq/L B. 0.5–0.8 mEq/L C. 1.0–1.3 mEq/L D. 1.5–2.5 mEq/L

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Pyrimethamine + sulfadoxine should be used as a: A. Clinical curative in areas with chloroquine resistant malaria B. Clinical curative in areas without chloroquine resistance among P. falciparum C. Prophylactic in areas with or without chloroquine resistance D. All of the above

Description : Pyrimethamine + sulfadoxine should be used as a: A. Clinical curative in areas with chloroquine resistant malaria B. Clinical curative in areas without chloroquine resistance among P. falciparum C. Prophylactic in areas with or without chloroquine resistance D. All of the above

Last Answer : A. Clinical curative in areas with chloroquine resistant malaria

elect the drug/combination that you will prescribe as a prophylactic to a resident of non-endemic area who got posted for 6 months to an endemic area with low degree chloroquine resistance among P. falciparum: A. Quinine B. Proguanil + Chloroquine C. Pyrimethamine + Sulfadoxine D. Artemisinin

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Last Answer : B. Proguanil + Chloroquine

If a drug is active against the preerythrocytic stage of the malarial parasite it will be useful as a: A. Suppressive prophylactic B. Causal prophylactic C. Clinical curative D. Radical curative

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Last Answer : B. Causal prophylactic

The following drug is a causal prophylactic for falciparum malaria and suppressive prophylactic for vivax malaria: A. Chloroquine B. Mepacrine C. Quinine D. Proguanil

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Last Answer : D. Proguanil

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