A patient of liver cirrhosis with ascitis was treated
with hydrochlorothiazide 50 mg twice daily. He
responded initially, but over a couple of months the
diuretic action gradually diminished and ascitis again
appeared. Select the measure to reinduce diuresis:
A. Increase hydrochlorothiazide dose to 100 mg
twice daily
B. Add acetazolamide 250 mg twice daily
C. Add spironolactone 50 mg thrice daily
D. Substitute hydrochlorothiazide by spironolactone 50 mg 6 hourly
with hydrochlorothiazide 50 mg twice daily. He
responded initially, but over a couple of months the
diuretic action gradually diminished and ascitis again
appeared. Select the measure to reinduce diuresis:
A. Increase hydrochlorothiazide dose to 100 mg
twice daily
B. Add acetazolamide 250 mg twice daily
C. Add spironolactone 50 mg thrice daily
D. Substitute hydrochlorothiazide by spironolactone 50 mg 6 hourly