Description : Blood does not clot in the blood vessels due to the presence of (1) Thrombin (2) Fibrinogen (3) Heparin (4) Prothrombin
Last Answer : Thrombin
Description : Tests of coagulation are used to monitor anticoagulation treatment and detect intrinsic abnormalities in coagulation. Which of the following statement(s) is/are true concerning ... is used to monitor heparin levels intraoperatively during cardiovascular and peripheral vascular operations
Last Answer : Answer: a, c, d Coagulation tests include prothrombin time (PT), which measures the intrinsic and extrinsic pathways of fibrinogen production and is the most common method for ... more while for peripheral vascular applications, values of 250 seconds or greater are considered appropriate
Description : The following are true about blood coagulation: a. heparin inhibits blood coagulation through its interference with vitamin K metabolism in the liver b. addition of vitamin K to freshly drawn ... delays clotting c. thrombin converts fibrinogen to fibrin d. platelets are essential for blood clot
Last Answer : thrombin converts fibrinogen to fibrin
Description : Blood fails to clot white flowing in the blood vessel because of the presence of (1) Heparin (2) Prothrombin (3) Haemoglobin (4) Hirudin
Last Answer : Heparin
Description : Which is the anticoagulant substance in blood? (1) Fibrinogen (2) Heparin (3) Thrombin (4) Globin
Last Answer : (2) Heparin Explanation: Heparin, a highly sulfated glycosaminoglycan, is widely used as an inject able anticoagulant, and has the highest negative charge density of any known ... because blood anti-coagulation is achieved mostly by heparin sulfate proteoglyeans derived from endothelial cells.
Description : Which is the anti-coagulant substance in blood? (1) Fibrinogen (2) Heparin (3) Thrombin (4) Globin
Description : he primary mechanism by which heparin prevents coagulation of blood is: A. Direct inhibition of prothrombin to thrombin conversion B. Facilitation of antithrombin III mediated inhibition of factor Xa and ... of antithrombin III to inhibit factors IX and XI D. Inhibition of factors XIIa and XIIIa
Last Answer : B. Facilitation of antithrombin III mediated inhibition of factor Xa and thrombi
Description : Vitamin K is required for (a) change of prothrombin into thrombin (b) synthesis of prothrombin (c) change of fibrinogen to fibrin (d) formation of thromboplastin.
Last Answer : (b) synthesis of prothrombin
Description : Assertion: Heparin is an anticoagulant found in mammals. Reason: Heparin prevents the conversion of prothrombin to thrombin
Last Answer : Assertion: Heparin is an anticoagulant found in mammals. Reason: Heparin prevents the conversion of ... . If both Assertion & Reason are false.
Description : Blood fails to clot white flowing in the blood vessel because of the presence of - (1) Hepatin (2) Prothrombin (3) liaemoglobin (4) Iltrudin
Last Answer : (1) Hepatin Explanation: Heparin also known as unfractionated heparin, a highly sulfated glycosaminoglycan, is widely used as an injectable anticoagulant, and has the highest negative charge density of any known biological molecule.
Description : Hemostasis and the cessation of bleeding require which of the following processes? A. Adherence of platelets to exposed subendothelial glycoproteins and collagen with subsequent aggregation of platelets and ... conversion of fibrinogen to fibrin. D. Cross-linking of fibrin by factor XIII.
Last Answer : Answer: ABCD DISCUSSION: Hemostasis requires the interaction of platelets with the exposed subendothelial structures at the site of injury followed by aggregation of more platelets in that area. ... form a stable clot that incorporates the platelet plug and fibrin thrombus into a stable clot
Description : Sickle cell disease is inherited due to defective copies of _________gene. a. Heparin b. Haemoglobin c. Creatinine d. Fibrinogen
Last Answer : b. Haemoglobin
Description : Assertion `:-` Porthrombinase enzymes converts prothrombin into active thrombin. Reason`:` Thrmoboplastin react with plasma protein in the presece of
Last Answer : Assertion `:-` Porthrombinase enzymes converts prothrombin into active thrombin. Reason`:` Thrmoboplastin ... If both Assertion & Reason are false.
Description : Which of the following statement(s) is/are true concerning hemophilia A? a. Hemophilia A is inherited as a sex-linked recessive deficiency of factor VIII b. A positive family history for ... platelet aggregation d. Spontaneous bleeding is unusual with factor VIII levels greater than 10% of normal
Last Answer : Answer: a, d Hemophilia A is inherited as a sex-linked recessive deficiency of factor VIII although 0% of cases are secondary to spontaneous mutation. The incidence of this abnormality is ... factor levels as low as 1% have been noted and patients are at risk for spontaneous bleeding
Description : The termination of heparin activity by protamine sulfate is due to (a) A chelating action (b) The inhibition of gastrointestinal absorption of heparin (c) The displacement of heparin-plasma protein binding (d) An acid-base interaction (e) The prothrombin-like activity of protamine
Last Answer : Ans: D
Description : The prothrombin time a. assess the extrinsic pathway of the blood coagulation cascade b. is prolonged in patients with fat absorption c. is increased by warfarin d. is increased by heparin
Last Answer : assess the extrinsic pathway of the blood coagulation cascade
Description : Prothrombin , albumin and fibrinogen are synthesised by
Last Answer : Prothrombin , albumin and fibrinogen are synthesised by A. Pancreas B. Bone marrow C. Spleen D. Liver
Description : Bleeding complications are frequently associated with fibrinolytic therapy. Which of the following statement(s) concerning complications of fibrinolytic therapy is/are true? a. Careful monitoring of prothrombin time ... months ago can be treated with fibrinolytic therapy if head CT scan is normal
Last Answer : Answer: b Fibrinolytic therapy induces a hemostatic defect through a combination of factors. Hypofibrinogenemia and fibrin degradation products inhibit fibrin polymerization and, in combination ... is considered a major relative contraindication to either regional or systemic thrombolytic therapy
Description : A 67-year-old male with advanced cholangiocarcinoma develops gram-negative sepsis. Excessive bleeding is noted around vascular catheters and from needle puncture sites. The diagnosis of disseminated ... b. Decreased fibrinogen level c. Normal prothrombin time d. Elevated fibrin split products
Last Answer : Answer: a, b, d Disseminated intravascular coagulation (DIC) is the primary form of acute thrombosis. Causes of this syndrome include abruptio placenta, gram-positive and gram-negative sepsis, ... decline in the platelet count and fibrinogen level, along with an elevation of fibrin split products
Description : Following is not the clotting factor ___________ a. Fibrinogen b. Prothrombin c. Hageman factor d. Ferritin
Last Answer : d. Ferritin
Description : As thrombin generation proceeds, the body has natural anticoagulant systems opposing further thrombus formation. Natural anticoagulants include: a. Tissue plasminogen activator (TPA) b. Antithrombin III c. Activated protein C d. Heparin cofactor II
Last Answer : Answer: b, c, d Just as thrombin generation is the key to coagulation, antithrombin III is the most central anticoagulant proteins. This glycoprotein binds to thrombin, preventing its removal of ... in the body. Therefore, TPA is part of the fibrinolytic system rather than a natural anticoagulant
Description : Mini-dose heparin has been shown to be useful in the prophylaxis of postoperative venous thrombosis. Mechanism(s) by which low-dose heparin is/are thought to protect against venous ... aggregation and subsequent platelet release action d. A mild prolongation of activated partial thromboplastin time
Last Answer : Answer: a, b, c Low-dose heparin is thought to protect against venous thrombosis through three different mechanisms. First, antithrombin III activity with its inhibition of activated Factor X is ... release reaction. The standard doses of heparin administered (5000 units bid) does not affect aPTT
Description : When compared to unfractionated heparin, low molecular weight heparins have (a) Preferential binding affinity to factor Xa relative to Iia (thrombin) (b) Shorter half-lives (c) Dose – dependent renal clearance
Last Answer : Ans: A
Description : Which of the following is not a blood clot in the blood vessels ?
Last Answer : Vitamin C helps in blood clotting.
Description : Which of the following statement(s) concerning laboratory studies used in monitoring a patient with intravenous heparinization is/are correct? a. The platelet count should be followed because of the ... serum creatinine should be measured daily to allow adjustments in dose based on renal function
Last Answer : Answer: a, c In monitoring the effect of heparin, an activated partial thromboplastin time (aPTT) of 1.5 control or a thrombin clotting time (TCT) of 2 times control reflects adequate ... system. Therefore the dose of heparin need not be adjusted in cases of liver or renal dysfunction
Description : Which of the following is not true about warfarin, a. INR of 3 is enough to start any extraction. b. Affects extrinsic system and increases prothrombin time. c. Heparin can be given subcutaneously ... rapidly. d. It takes at least 12 hours for Vitamin K to reverse the effects of coumarin.
Last Answer : d. It takes at least 12 hours for Vitamin K to reverse the effects of coumarin.
Description : Which of the following is not true about warfarin, ** A. INR of 3 is enough to start any extraction B. Affects extrinsic system and decreases prothrombin time C. Heparin can be given subcutaneously and acts rapidly D. It takes up to 12 hours for Vitamin K to reverse the effects of warfarin
Last Answer : B. Affects extrinsic system and decreases prothrombin time
Description : Patient on anti-coagulant therapy requires an extraction to be performed. Which of the following is NOT true: A. Minor post operative bleedings can be reduced somehow by using tranexamic acid B. ... takes at least 8 hours for heparin to take effects D. Heparin should be administered sub-cutaneous
Last Answer : C. It takes at least 8 hours for heparin to take effects
Description : Low doses of heparin prolong: A. Bleeding time B. Activated partial thromboplastin time C. Prothrombin time D. Both ‘B’ and ‘C’
Last Answer : B. Activated partial thromboplastin time
Description : Blood does not coagulate inside the body due to the presence of (a) haemoglobin (b) heparin (c) fibrin (d) plasma
Last Answer : Ans:(b)
Description : Blood does not coagulate inside the body due to the presence of – (1) Plasma (2) Haemoglobin (3) Heparin (4) Fibrin
Last Answer : (3) Heparin Explanation: Heparin is a naturally-occurring anticoagulant produced by basophils and mast cells. Heparin acts as an anticoagulant, preventing the formation of clots and extension of existing clots ... is present in the walls of blood vessels where it doesn't allow blood to clot.
Description : Blood does not coagulate inside the body due to the presence of (1) Plasma (2) Haemoglobin (3) Heparin (4) Fibrin
Description : Assertion `:` Prothrombinase enzyme act as antiheparin Reason `:` Heparin prevent coagulation of blood in Blood vessels
Last Answer : Assertion `:` Prothrombinase enzyme act as antiheparin Reason `:` Heparin prevent coagulation of blood in ... D. If both Assertion & Reason are false.
Description : Platelets play an important role in haemostasis; which of the following describes this role? A. They convert fibrinogen to fibrin B. They agglutinate and plug small, ruptured ... thrombosis D. They supply fibrin stabilizing factors E. They supply proconvertin for thromboplastin activation
Last Answer : B. They agglutinate and plug small, ruptured vessels
Description : Blood clot is mainly due to
Last Answer : Blood clot is mainly due to A. Fibrin `+` Corpuscles B. Heparin `+` Corpuscles C. Plasma `+` Thrombocytes D. Plasma `+` RBC
Description : With regard to the choroid: a. the choroid receives 85% of blood flow to the eye b. the blood vessels in the choroid contains tight junction c. the choroid vessels are embedded in ... d. in the presence of high partial pressure of carbon dioxide the choroidal vessels increase in diameter
Last Answer : in the presence of high partial pressure of carbon dioxide the choroidal vessels increase in diameter
Description : It causes clotting of blood - (1) Thrombin (2) Haemoglobin (3) Pectin (4) All of the above
Last Answer : (1) Thrombin Explanation: There are two major facets of the clotting mechanism - the platelets, and the thrombin system. The thrombin system consists of several blood proteins that, when bleeding occurs, become ... called fibrin. Red blood cells become caught up in the web, and a "red clot" forms.
Description : A patient who has been taking quantities of aspirin might show increased post operative bleeding because aspirin inhibits:** A. Synthesis of thromboxane A2 and prevents platelet aggregation B. ... network E. Increase the absorption of vitamin K and prevents synthesis of blood clotting factors
Last Answer : A. Synthesis of thromboxane A2 and prevents platelet aggregation
Description : When a wound occurs in humans, the platelets in th blood activate a substance which starts the clotting process. The substance which starts the clotting is: a) adenosine (pron: ah-den-ah-seen) b) histamine c) lecithin (pron: less-ah-thin) d) thrombin
Last Answer : ANSWER: D -- Thrombin
Description : It causes clotting of blood (1) Thrombin (2) Haemoglobin (3) Pectin (4) All of the above
Description : The following is true of bezafibrate except: A. It activates lipoprotein lipase B. It mainly lowers serum triglyceride level with smaller effect on LDL cholesterol level C. It increases the incidence of myopathy due to statins D. It tends to lower plasma fibrinogen level
Last Answer : C. It increases the incidence of myopathy due to statins
Description : What is the function of Fibrinogen in blood? -Biology
Last Answer : answer:
Description : Which one of the following is correct? (a) Lymph = Plasma + RBC + WBC (b) Blood = Plasma + RBC + WBC + Platelets (c) Plasma = Blood – Lymphocytes (d) Serum = Blood + Fibrinogen
Last Answer : (b) Blood = Plasma + RBC + WBC + Platelets
Description : Match the items given in column I with those in column II and select the correct option given below. Column I Column II A. Fibrinogen (i) Osmotic balance B. Globulin (ii) Blood clotting C. Albumin (iii)Defence mechanism A B C (a) ( ... i) (b) (i) (ii) (iii) (c) (i) (iii) (ii) (d) (ii) (iii) (i)
Last Answer : (d) (ii) (iii) (i)
Description : Which of the following is not found in blood? a) fibrinogen b) glucose c) urea d) glycogen
Last Answer : ANSWER: D -- GLYCOGEN
Description : What does a blood clot in the arm feel like and is the only way you know here is one by swelling and redness and hot to the touch?
Last Answer : Go to the ER if you’re really worried you’ll die before you get a chance to go to the doctor.
Description : Superficial blood clot, and taking anticoagulants, surgery or not?
Last Answer : If you want a third opinion, I’d say ask a third surgeon?
Description : Which medicine does not allow blood to clot ?
Last Answer : Heparin does not allow blood to clot.
Last Answer : Anti coagnlant drug does not allow blood to clot in the body
Description : What is destruction of a blood clot in medical terms?
Last Answer : thrombolysis