Description : Which one of the following effects does not occur in salicylate intoxication ? (a) Hyperventilation (b) Hypothemia (c) Metabolic acidosis (d) Respiratory alkalosis (e) Tinnitus
Last Answer : Ans: B
Description : Metabolic effects that generally attend antiinflammatory doses of aspirin include the following except: A. Increased CO2 production B. Hepatic glycogen depletion C. Metabolic acidosis D. Compensated respiratory alkalosis
Last Answer : C. Metabolic acidosis
Description : Accidental poisonings are common with both aspirin and ibuprofen, two OC drugs available in tasty chewable tablets. In cases of overdose, aspirin is more likely than ibuprofen to cause (a) ... Instability (b) Hepatic necrosis (c) Metabolic acidosis (d) Thrombocytopenia (e) Ventricular arrhythmias
Last Answer : Ans: C
Description : Potential adverse effects associated with aspirin include all of the following except (a) Gastrointestinal ulceration (b) Renal dysfunction (c) Enhanced methotrexate toxicity (d) Cardiac arrhythmias (e) Hypersensitivity asthma
Last Answer : Ans: E
Description : Respiratory acidosis is that in which the blood pH is low due to increased retention of carbon dioxide caused by the lowering of the respiratory frequency or by pulmonary diseases that impair ... caused by metabolic disturbances that increase the concentration of bases (alkalis) in the blood.
Last Answer : Where are the chemoreceptors that detect the acidity of the blood and trigger the respiratory compensation located?
Description : Salicylate poisoning can cause (A) Respiratory acidosis (B) Metabolic acidosis with normal anion gap (C) Metabolic acidosis with increased anion gap (D) Metabolic alkalosis
Last Answer : Answer : C
Description : Total CO2 is increased in (A) Respiratory acidosis (B) Metabolic alkalosis (C) Both respiratory acidosis and metabolic alkalosis (D) Respiratory alkalosis
Description : Plasma bicarbonate is increased in (A) Respiratory alkalosis (B) Metabolic alkalosis (C) Respiratory acidosis (D) Metabolic acidosis
Last Answer : Answer : B
Description : Which of the following may precipitate an asthma attack? (a) Respiratory acidosis (b) Viran and bacterial infections (c) Respiratory alkalosis (d) Cranberry jiuce (e) Chocolate or Coca Cola
Description : Hypercholremia is associated with (A) Hyponatremia (B) Hypernatremia (C) Metabolic alkalosis(D) Respiratory acidosis
Description : Salicylate poisoning in early stages causes (A) Metabolic acidosis (B) Respiratory acidosis (C) Metabolic alkalosis (D) Respiratory alkalosis
Last Answer : Answer : D
Description : Morphine poisoning causes (A) Metabolic acidosis (B) Respiratory acidosis (C) Metabolic alkalosis (D) Respiratory alkalosis
Description : Meningitis and encephalitis cause (A) Metabolic alkalosis (B) Respiratory alkalosis (C) Metabolic acidosis (D) Respiratory acidosis
Description : Plasma bicarbonate is decreased in (A) Respiratory alkalosis (B) Respiratory acidosis (C) Metabolic alkalosis (D) Metabolic acidosis
Description : Which type of patient is most likely to hypersensitive to aspirin? (a) Intrinsic asthamatic (b) Extrinsic asthamatic (c) Chronic bronchitic (d) Patient with viral injection (e) Both (c) and (d)
Last Answer : Ans: A
Description : The primary objective for designing drugs that selectively inhibit COX - 2 is to (a) Decrease the risk of nephrotoxicity (b) Improve anti-inflammatory effectiveness (c) Lower the ... of treatment of rheumatoid arthritis (e) Selectively decrease thromboxane A2 without effects on other eicosanoids
Description : A 65-year-old is interested in taking ginkgo. Which of the following statements is correct regarding ginkgo? (a) Ginkgo is contraindicated in diabetes and pregnancy (b) There is a ... drug-herb interaction between ginkgo and phenelzine (e) Ginkgo is contraindicated in patients with gallstone pain
Description : Aspirin is contraindicated in children suffering from influenza or similar viral infection because of increased risk of: A. Gastric bleeding B. Thrombocytopenia C. Fancony syndrome D. Reye’s syndrome
Last Answer : D. Reye’s syndrome
Description : Acute or chronic colchicine toxicity may be identified by which of the following signs/symptoms? (a) Alopecia (b) Blood dyscrasias (c) Severe gastrointestinal upset (d) All of the above (e) None of the above
Last Answer : Ans: D
Description : All of the following medications should not be used routinely in pregnant patients during the third trimester except (a) Acetaminophen (b) Nonsteroidal anti-inflammatory drugs (c) Warfarin (d) Lithium (e) Aspirin
Description : Which of the following medications would represent arthritis therapy that is least likely to cause gastric ulceration? (a) Aspirin (b) Acetaminophen (c) Piroxicam (d) Meclofenamate (e) Rofecoxib
Description : The action of aspirin that results in its greater efficacy as an antithrombotic (anti-platelet) drug is its ability to (a) Inhibit lipoxygenase as well as cyclooxygenase (b) Selectively inhibit ... I (c) Inhibit leukocyte migration (d) Promote uric acid excretion (e) Acetylate cyclooxygenase
Description : Which of the following compounds is most likely to lower circulating levels of leukotrienes? (a) Zileuton (b) Montelukast (c) Carprofen (d) Aspirin (e) Allopurinol
Description : A 45-year-old surgeon has developed symmetric early morning stiffness in her hands. She wishes to take a nonsteroidal anti-inflammatory drug to relieve these symptoms and wants to avoid gastrointestinal side ... appropriate? (a) Aspirin (b) Celecoxib (c) Ibuprofen (d) Indomethacin (e) Piroxicam
Description : The main advantage of ketorolac over aspirin is that ketorolac (a) Can be combined more safely with an opioid such as codeine (b) Can be obtained as an over-the-counter agent (c) Does not ... (e) Is less likely to cause acute renal failure in patients with some preexisting degree of renal impairment
Description : Which one of the following drugs is not useful in dysmenorrhea? (a) Aspirin (b) Colchicine (c) Ibuprofen (d) Rofecoxib (e) Naproxen
Description : Which of the following is a reversible inhibitor of platelet cyclooxygenase? (a) Alprostadil (b) Aspirin (c) Ibuprofen (d) LTC4 (e) Misoprostol
Description : Name the chronic respiratory disorder caused mainly by cigarette smoking. (a) Respiratory acidosis (b) Respiratory alkalosis (c) Emphysema (d) Asthma
Last Answer : (c) Emphysema
Description : Cyclooxygenase-1 and –2 are responsible for (a) The synthesis of prostaglandins from arachidonate (b) The synthesis of leukotrienes from arachidonate (c) The conversion of ATP to cAMP (d) The metabolic degradation of cAMP (e) The conversion of GTP to cGMP
Description : In the treatment of chronic inflammatory diseases, the most important limitation of aspirin is (a) Acid – base and electrolytc disturbances (b) Hypersensitivity and idiosyncratic reactions (c) Gastric mucosal damage (d) Salicylism
Description : Aspirin reduces fever by (a) Decreasing heat production in the body (b) Enhancing cutaneous blood flow (c) Inducing sweating (d) Both (b) and (c)
Description : Aspirin produces analgesia by (a) Preventing sensitization of peripheral pain receptors (b) Affecting gating of pain impulses at spinal level (c) Raising pain threshold at subcortical level (d) Both (a) and (b)
Description : An opioid analgesic is preferred over aspirin like analgesic in the following condition. (a) Acute gout (b) Burn (c) Toothache (d) Neuralgia
Description : Instead of being effective in hyperuricaemia following drug is contradictred in the treatment of gout (a) Indomethacin (b) Diclofenac (c) Piroxicam (d) Aspirin
Description : Aspirin in low doses produces longlasting inhibition (a) Platelets contain low quantity of COX (b) Platelets cannot synthesize fresh COX molecules (c) Platelets bind aspirin with high affinity (d) Platelet COX is inducible
Description : Which of the following is an irreversible inhibitor of cyclooxygenase ? (a) Aspirin (b) Phenylbutazone (c) Indomethacin (d) Piroxicam
Description : The cyclooxygenase isoenzymes COX-1 and COX-2 differ from each other in that (a) They catalyse different pathways in prostanoid biosynthesis (b) COX–1 is inhibited by aspirin but not COX–2 (c) COX–2 is inhibited by ibuprofen but not COX–1 (d) COX–1 is constitutive while COX–2 is inducible
Description : The greatest threat from morphine poisoning is (a) Renal shutdown (b) Paralysis of spinal cord (c) Respiratory depression (d) Cardiovascular collapse (e) None of the above
Description : Fentanyl transdermal patches have been used postoperatively to provide transdermal analgesia. The most dangerous adverse effect of this mode of administration is (a) Cutaneous reactions (b) Diarrhea (c) Hypertension (d) Relaxation of skeletal muscle (e) Respiratory depression
Description : Which action of morphine is incompletely reversed by naloxone ? (a) Analgesia (b) Respiratory depression (c) Sedation (d) Miosis
Description : Opioid analgesics are either contraindicated or must be used with extreme caution in several clinical situations. For morphine, such situations do not include (a) Aqueous diffusion (b) Aqueous hydrolysis (c) Lipid diffusion (d) Pinocytosis or endocytosis (e) Special carrier transport
Description : Agents that often cause vasoconstriction include all of the following except (a) Angiotensin II (b) Methysergide (c) PGF2a (d) Prostacyclin (e) Thromboxane
Description : Which of the following features are present in blood chemistry in uncompensated metabolic alkalosis except? (A) Increased pH (B) Increased bicarbonate (C) Normal chloride (D) Normal pCO2
Description : Anion gap is increased in (A) Renal tubular acidosis (B) Metabolic acidosis resulting from diarrhoea (C) Metabolic acidosis resulting from intestinal obstruction (D) Diabetic ketoacidosis
Description : The following adverse effect of corticosteroids is due to their mineralocorticoid action (a) Osteoporosis (b) Rise in blood pressure (c) Moon face (d) Increased susceptibility to infection
Description : Cervical priming with prostaglandin results in (a) Facilitation of sperm movement through cervical canal (b) Increased cervical tone (c) Softening of cervix (d) Increased cervical secretions
Description : Does anybody know what to avoid eating with peptic ulcers?
Last Answer : Do you know that ulcers are the cause of your symptoms?
Description : what are sighns of peptic ulcers?
Last Answer : I have a peptic ulcer. Can that cause cancer?
Description : What is true of acid control therapy with H2 blockers: A. It generally heals duodenal ulcers faster than gastric ulcers B. It checks bleeding in case of bleeding peptic ulcer C. It prevents gastroesophageal reflux D. Both ‘A’ and ‘B’ are correct
Last Answer : A. It generally heals duodenal ulcers faster than gastric ulcers
Description : During compensation of respiratory alkalosis, all the following changes occur except (A) Decreased secretion of hydrogen ions by renal tubules (B) Increased excretion of sodium in urine (C) Increased excretion of bicarbonate in urine (D) Increased excretion of ammonia in urine