Description : Answer: b, c, d Eosinophils constitute 1% to 3% of the leukocyte population of the bloodstream. They also reside in tissues and they exhibit phagocytic capabilities. They are less ... the cycle of events that result in recruitment and activation of inflammatory cells at sites of inflammation
Last Answer : Cellular injury from oxidants may be manifest by which of the following? a. Cell membrane lipid peroxidation b. DNA strand breaks c. Cytoskeletal disassembly d. ATP depletion
Description : Which type of white blood cells are concerned with the release of histamine and the natural anticoagulant heparin ?
Last Answer : Which type of white blood cells are concerned with the release of histamine and the natural ... Eosinophils B. Monocytes C. Neutrophils D. Basophils
Description : Which type of white blood cells are concerned with the release of histamine and the natural anticoagulant heparin? (a) Eosinophils (b) Monocytes (c) Neutrophils (d) Basophils
Last Answer : d) Basophils
Description : Hashimoto disease and Graves‘ disease are similar in that both a. Affect the thyroid gland. b. Affect the red blood cells. c. Are forms of cellular hypersensitivity? d. Are accompanied by histamine release.
Last Answer : b. Affect the red blood cells.
Description : Cytotoxic T cells release which 2 toxic proteins as they fight target cells? a. histamine and heparin b. perforin and granzymes c. interleukin and interferon d. lysozymes and cytokines
Last Answer : b. perforin and granzymes
Description : The drug that can directly release histamine from mast cells without involving antigen-antibody reaction is: A. Aspirin B. Procaine C. Morphine D. Sulfadiazine
Last Answer : C. Morphine
Description : Assertion : Histamine is related with allergic and inflamatory reactions Reason : Histamine is a vasodilator
Last Answer : Assertion : Histamine is related with allergic and inflamatory reactions Reason : Histamine is a ... If both the assertion and reason are false
Description : The most important preformed mediator of allergic reactions is/are a. Prostaglandin b. Interleukin c. Histamine d. Leukotrienes
Last Answer : c. Histamine
Description : Assertion . Mast cells in human body release excessive amount of inflammatory chemicals which cause allergic reactions. Reason . Allergens in the envi
Last Answer : Assertion . Mast cells in human body release excessive amount of inflammatory chemicals which cause ... If both the assertion and reason are false
Description : Increasing evidence has implicated gram-negative bacterial lipopolysaccharide (LPS endotoxin) as the portion of the gram-negative bacterial cell membrane responsible for many, if not all the ... host, exerting deleterious effects on the host when excessive amounts reach the systemic circulation
Last Answer : Answer: a, b, d The LPS molecule exerts diverse effects on the mammalian host. Immunologic responses to LPS include nonspecific polyclonal B-cell proliferation, macrophage activation and ... deleterious effects on the host only after large amounts are secreted and reach the systemic circulation
Description : Which of the following statement(s) is/are true concerning the neuroendocrine responses to shock? a. Sympathetic nerve endings release epinephrine which is responsible for greater than 80% ... injury and sepsis d. The renin-angiotensin axis further augments the sympathetic-mediated vasoconstriction
Last Answer : Answer: c, d The neuroendocrine response to shock attempts to achieve restoration of effective blood volume, mobilization of metabolic substrates, and maintenance of central ... . Angiotensin II is an extremely effective vasoconstrictor that further augments sympathetic-mediated vasoconstriction
Description : Eicosanoids mediate inflammation in a variety of ways. Of the following statements, which are true with regard to this? a. Eicosanoids are stored in cytoplasmic granules ... include vasodilatation, vasoconstriction, increased vascular permeability and both chemotaxis and chemoattractant inhibition
Last Answer : Answer: b, d The eicosanoids are derived from arachidonic acid (eicosatetraenoic acid) and consist of prostaglandins, thromboxanes, leukotrienes and lipoxins. The eicosanoids are not ... nervous system d. Mononuclear phagocytes release a variety of proinflammatory cytokines and growth factors
Description : What are the rarest of WBCs that release histamine and exaggerate the inflammatory response?
Last Answer : Need answer
Description : Zinc is involved in storage and release of (A) Histamine (B) Acetylcholine (C) Epinephrine (D) Insulin
Last Answer : Answer : D
Description : Edema associated with decreased plasma oncotic pressure may be caused by C A. Sodium depletion B. Histamine release C. Liver disease D. None of these
Last Answer : Liver disease
Description : Match the following columns and select the correct option. Column-I Column - II (A) Eosinophils (i) Immune response (B) Basophils (ii) Phagocytosis (C) Neutrophils (iii) Release histaminase, destructive enzymes (D) Lymphocytes (iv) ... (iii) (c) (i) (ii) (iv) (iii) (d) (ii) (i) (iii) (iv)
Last Answer : (a) (iii) (iv) (ii) (i)
Description : By which of the following mechanism reduces Aspirin pain: A. It is anti inflammatory by the release of histamine B. It blocks the cyclo-oxygenase pathway.
Last Answer : B. It blocks the cyclo-oxygenase pathway.
Description : Opioid analgesics reduce pain by the release of which naturally appearing product:CHECK A. Serotonin B. Histamine C. Enkephalins/endomorphins/endorphins/dynorphines
Last Answer : C. Enkephalins/endomorphins/endorphins/dynorphines
Description : Morphine induced fall in blood pressure involves the following factors except: A. Direct cardiac depression B. Direct reduction of vascular tone C. Vasomotor centre depression D. Histamine release
Last Answer : A. Direct cardiac depression
Description : The following factor is not involved in the causation of hypotension due to spinal anaesthesia: A. Histamine release B. Reduced sympathetic vasoconstrictor tone C. Decreased venous return from the lower limbs D. Bradycardia
Last Answer : A. Histamine release
Description : Neostigmine reverses the following actions of d-tubocurarine except: A. Motor weakness B. Ganglionic blockade C. Histamine release D. Respiratory paralysis
Last Answer : C. Histamine release
Description : Which of the following is applicable to mivacurium: A. It undergoes Hoffmann elimination B. It is the shortest acting nondepolarizing neuromuscular blocker C. It is excreted unchanged by kidney D. It does not cause histamine release
Last Answer : B. It is the shortest acting nondepolarizing neuromuscular blocker
Description : Succinylcholine is the preferred muscle relaxant for tracheal intubation because: A. It produces rapid and complete paralysis of respiratory muscles with quick recovery B. It does not alter heart rate or ... C. It does not cause histamine release D. It does not produce postoperative muscle soreness
Last Answer : A. It produces rapid and complete paralysis of respiratory muscles with quick recovery
Description : Pancuronium differs from tubocurarine in that: A. It is a depolarizing blocker B. Its action is not reversed by neostigmine C. It can cause rise in BP on rapid I.V. injection D. It causes marked histamine release
Last Answer : C. It can cause rise in BP on rapid I.V. injection
Description : Select the skeletal muscle relaxant that is commonly used for endotracheal intubation despite causing histamine release, K+ efflux from muscles and cardiovascular changes: A. Pipecuroniun B. Succinylcholine C. Pancuronium D. Cisatracurium
Last Answer : B. Succinylcholine
Description : The fall in blood pressure caused by d-tubocurarine is due to: A. Reduced venous return B. Ganglionic blockade C. Histamine release D. All of the above
Last Answer : D. All of the above
Description : The action of histamine that is not mediated through H1 receptors is: A. Release of EDRF from vascular endothelium resulting in vasodilatation B. Direct action on vascular smooth muscle causing vasodilatation C. Bronchoconstriction D. Release of catecholamines from adrenal medulla
Last Answer : B. Direct action on vascular smooth muscle causing vasodilatation
Description : During the course of a cellular hypersensitivity a. Antibodies react with antigens in tissues. b. Serotonin and histamine are released by cells. c. Immune complexes form on blood vessel surfaces. d. A skin thickening called an induration may form.
Last Answer : b. Serotonin and histamine are released by cells.
Description : Muscarinic cholinergic receptors (a) Are located only on parasympathetically innervated effector cells (b) Mediate responses by opening an instrinsic Na+ ion channel (c) Are present on vascular endothelium which has no cholinergic nerve supply (d) Predominate in the autonomic ganglia
Last Answer : Ans: C
Description : Second messengers a. are substances that interact with first messengers inside cells b. are substances that bind to first messengers in the cell membrane c. are hormones secreted by cells ... the intracellular responses to many different hormonesand neurotransmitters e. are not formed in the brain
Last Answer : mediate the intracellular responses to many different hormonesand neurotransmitters
Description : Which of the following responses identifies a role of T lymphocytes? a) Transplant rejection Transplant rejection and graft-versus-host disease are cellular response roles of T cells. ... ) Bacterial phagocytosis and lysis Bacterial phagocytosis and lysis are humoral response roles of Blymphocytes.
Last Answer : a) Transplant rejection Transplant rejection and graft-versus-host disease are cellular response roles of T cells.
Description : Muscarinic cholinergic receptors: A. Are located only on parasympathetically innervated effector cells B. Mediate responses by opening an intrinsic Na+ ion channel C. Are present on vascular endothelium which has no cholinergic nerve supply D. Predominate in the autonomic ganglia
Last Answer : C. Are present on vascular endothelium which has no cholinergic nerve supply
Description : Histamine is synthesised in (A) Brain (B) Mast cells (C) Basophils (D) All of these
Description : Histamine (a) May be released from mast cells by a number of therapeutic agents (b) Causes sedation (c) Decreases the force of contraction of ventricular muscle (d) Can cause strong contractions of the gravid human uterus
Last Answer : Ans: D
Description : A mast cell (or mastocyte) is a resident cells of several types of tissues and contains many granules rich in_______. a) Acetylcholine b) Nicotine c) Epinephrine d) Histamine e) Histadine
Description : Polymorphonuclear neutrophil granulocytes A A. are important cells in bacterial infections B. play a role in inflammation by releasing histamine C. are important cells in neoplastic conditions D. play an important role in viral infections
Last Answer : are important cells in bacterial infections
Description : Histamine secreting cells are found in (a) connective tissues (b) lungs (c) muscular tissue (d) nervous tissue
Last Answer : (a) connective tissues
Description : In mammals, histamine is secreted by (a) lymphocytes (b) mast cells (c) fibroblasts (d) histiocytes.
Last Answer : b) mast cells
Description : Mast cells of connective tissue contain (a) vasopressin and relaxin (b) heparin and histamine (c) heparin and calcitonin (d) serotonin and melanin.
Last Answer : (b) heparin and histamine
Description : Mast cells secrete (a) haemoglobin (b) hippurin (c) myoglobin (d) histamine
Last Answer : (d) histamine.
Description : Acquired immunity consists of humoral immunity maintained by _____ and _____, and cell-mediated immunity controlled by _____ a. T cells, complement, B cells b. T cells, Interleukin, B cells c. B cells, antibodies, T cells d. B cells, histamine, T cells
Last Answer : c. B cells, antibodies, T cells
Description : ________ bind to_________ on microbial invaders. a. Toll-like receptors; PAM Ps b. Mast cells; histamine c. Toll-like receptors; complement d. Macrophages; defensins
Last Answer : a. Toll-like receptors; PAM Ps
Description : Which of the following body substances causes increased gastric secretion, dilation of capillaries, and constriction of the bronchial smooth muscle? a) Histamine When cells are damaged, ... Prostaglandin Prostaglandins are unsaturated fatty acids that have a wide assortment of biologic activity.
Last Answer : a) Histamine When cells are damaged, histamine is released.
Description : Which of the following medications represents the category proton (gastric acid) pump inhibitors? a) Omeprazole (Prilosec) Omeprazole decreases gastric acid by slowing the hydrogenpotassium-adenosine ... antagonist. d) Metronidazole (Flagyl) Metronidazole is an antibiotic, specifically an amebicide.
Last Answer : a) Omeprazole (Prilosec) Omeprazole decreases gastric acid by slowing the hydrogenpotassium-adenosine-triphosphatase pump on the surface of the parietal cells.
Description : Which one of the following statements is false ? Allergic asthma is characterized by: a) Response to cyclosporin therapy in severe disease. b) Is characterised by reversible airways obstruction. c) T2 ... fluid. d) Affects 5% of the population. e) Is diagnosed routinely by use of ELISA
Last Answer : Ans: E
Description : In higher vertebrates, the immune system can distinguish self-cells and non-self. If this property is lost due to genetic abnormality and it attacks self- cells, then it leads to (a) autoimmune disease (b) active immunity (c) allergic response (d) graft rejection.
Last Answer : (a) autoimmune disease
Description : Asthma may be attributed to (a) inflammation of the trachea (b) accumulation of fluid in the lungs (c) bacterial infection of the lungs (d) allergic reaction of the mast cells in the lungs.
Last Answer : (d) allergic reaction of the mast cells in the lungs.