Description : Which of the following reaction is called Augmented adverse drug reactions? a) Genetically determined effects. b) Idiosyncracy. c) Rebound effect on discontinuation d) Allergic reactions & anaphylaxis.
Last Answer : c) Rebound effect on discontinuation
Description : Which of the following patients are at the highest risk of suffering from an adverse drug reaction? a) An 8 month year old infant receiving a prescription for an antibiotic. b) A 22 year old patient ... ACE Inhibitor. d) A 68 year old patient who has oedema receiving a prescription for a diuretic.
Last Answer : d) A 68 year old patient who has oedema receiving a prescription for a diuretic.
Description : A 75-year-old man had been receiving gentamicin (an aminoglycoside antibiotic) to treat an urinary tract infection. After three months of therapy patient's serum creatinine levels were 10 mg/ ... Type II allergic reaction b)Type III allergic reaction c) Pseudo allergic reaction d) Overdose toxicity
Last Answer : d) Overdose toxicity
Description : What is informed consent in a clinical trial? a) The subjects do not know which study treatment they receive b) Patients injected with placebo and active doses c) Fake treatment d) Signed document of the recruited patient for the clinical trial procedures
Last Answer : d) Signed document of the recruited patient for the clinical trial procedures
Description : Which of the following adverse drug reactions would you report to the Medicines and Healthcare Products regulatory Agency (MHRA) via the yellow card system for reporting? a) A patient ... started taking ramipril. d) A patient complains they have experienced diarrhoea since taking azilsartan.
Last Answer : d) A patient complains they have experienced diarrhoea since taking azilsartan.
Description : ___________ is an example of latent adverse drug reactions. a) Antibiotic-associated diarrhea b) Tardive dyskinesia c) Serum sickness d) Severe bronchoconstriction
Last Answer : D
Description : Which one of these is a genetically determined adverse drug reactions? a) Addication. b) Teratogenecity. c) Carcinogenicity. d) Idiosyncracy.
Last Answer : b) Teratogenecity.
Description : Idiosyncrasy is_______________. a) Type A ADRs b) Type B ADRs c) Type C ADRs d) Type D ADRs
Last Answer : b) Type B ADRs
Description : According to Rawlins–Thompson classification Type D ADR includes___________ a) Carcinogenesis b) Bradycardia associated with beta blockers c) Anaphylaxis associated with penicillin d) Opiate withdrawal syndrome
Last Answer : a) Carcinogenesis
Description : Which of the following is a type B (unpredictable) adverse drug reaction: A. Side effect B. Toxic effect C. Idiosyncrasy D. Physical dependence
Last Answer : A. Side effect
Last Answer : C. Idiosyncrasy
Description : In an anaesthetized dog, repeated intravenous injection of ephedrine shows the phenomenon of: A. Anaphylaxis B. Tachyphylaxis C. Idiosyncrasy D. Drug resistance
Last Answer : B. Tachyphylaxis
Description : Science of collecting, monitoring, researching, assessing and evaluating information from healthcare providers and patients on the adverse effects of medications is known as a) Pharmacovigilance. b) Clinical Trails. c) Observational study. d) Qualitative study.
Last Answer : a) Pharmacovigilance.
Description : Which of the following statements best describes a lead compound? a) A compound that contains the element lead b) A compound from the research laboratory that is chosen to go forward for preclinical and ... of a drug. d) The first compound of a structural class of compounds to reach the market.
Last Answer : c) A molecule that shows some activity or property of interest and serves as the starting point for the development of a drug.
Description : Pharmacovigilance is done for monitoring of a) Drug price b) Unethical practises c) Drug safety d) Pharmacy students
Last Answer : c) Drug safety
Description : Patient counselling helps to a) Know chemical structure of drug b) Develop business relations with pharmacist c) Motivate the patient to take medicine for improvement of his/her health status. d) Pass time at old age
Last Answer : c) Motivate the patient to take medicine for improvement of his/her health status.
Description : Which of the following drug is not needed to be TDM? a) Carbamazepine. b) Penicillin. c) Digoxin. d) Gentamicin.
Last Answer : b) Penicillin.
Description : The purpose of preclinical testing is: a. To verify that a drug is sufficiently safe and effective to be tested in humans. b. To undergo preliminary testing in healthy humans to monitor the ... for the larger scale future tests on a widespread population. d. To develop method of drug analysis
Last Answer : a. To verify that a drug is sufficiently safe and effective to be tested in humans.
Description : Case control studies is called as A. Drug-oriented systems. B. Dose-oriented systems. C. Disease-oriented systems. D. Complication-oriented systems.
Last Answer : B. Dose-oriented systems.
Description : Which of the following drug can result in result in cyanide poisoning? A. Amyl nitrite B. Hydroxycobalamine C. Sodium nitroprusside D. Sodium thiosulphate
Last Answer : C. Sodium nitroprusside
Description : Which of the following drug is implicated in the causation of osteomalacia of the bone? A. Steroid B. Estrogen C. Heparin D. Phenytoin
Last Answer : D. Phenytoin
Description : The highest serum drug concentration following a single dose or at a steady state within a dosing interval is called ………. A. Lead B. Peak C. Poison D. Mechanisms
Last Answer : B. Peak
Description : _________ drug is avoided in children’s under 4 years with diarrhea. a) bisacodyl b) loperamide c) Bismuth subsalicylate d) Ciprofloxacin
Last Answer : d) Ciprofloxacin
Description : ___________ drug is usually avoided with breastfeeding. a) Ibuprofen b) propranalol c) Methotrexate d) Naproxe
Last Answer : c) Methotrexate
Description : ___________ antidiabetic drug is preferred for elderly patient a) Gliclazide b) Glibencamide c) Metformin d) Pioglitazone
Last Answer : a) Gliclazide
Description : Which of the following drug does not require therapeutic drug monitoring? a) Digitoxin. b) Gentamycin. c) Phenytoin. d) Paracetamol
Last Answer : d) Paracetamol
Description : ________________ causes pharmacodynamic drug interaction. a) Gastric motility changes. b) Stimulation of metabolism. c) Alteration of pH of GIT. d)Interactions at receptor site.
Last Answer : d)Interactions at receptor site.
Description : The most specific & sensitive method for assessment of compliance can be used to detect potent therapeutic agent in body fluids is a) Drug analysis. b) Interrogation. c) Urine marker. d) Residual Tablet counting.
Last Answer : a) Drug analysis.
Description : Which of the following responsibility of community pharmacist is in dispensing area? a) Reviews all doses missed, reschedule the doses as necessary & signs all drugs not given notices. b ... of each patient's drug administration forms periodically to ensure all doses have been administered.
Last Answer : b) Supervision of drug administration.
Description : Which of the following responsibility of the clinical pharmacist is in direct patient care area? a) Supervision of drug administration techniques. b) Providing drug information to physicians and ... of each patient's drug administration forms periodically to ensure all doses have been administered.
Last Answer : d) Reviewing of each patient’s drug administration forms periodically to ensure all doses have been administered.
Description : ___________ drug can cause lactic acidosis. a) Metformin b) Pioglitazone c) Repaglinide d) Glibenclamide
Last Answer : a) Metformin
Description : An undesirable effect of a drug that occurs at therapeutic doses and can be predicted from its pharmacological actions is called: A. Side effect B. Toxic effect C. Allergic reaction D. Idiosyncrasy
Description : Why should care be taken when prescribing warfarin and amiodarone in combination? A. Amiodarone and warfarin both have an anticoagulant effect. B. Amiodarone may reverse the anticoagulant ... anticoagulant effect of warfarin. D. Warfarin may reverse the antiarrhythmic effect of amiodarone.
Last Answer : C. Amiodarone may increase the anticoagulant effect of warfarin.
Description : __________ is the common and dose related side effect of salbutamol. a) Decrease in blood pressure b) Muscle tremor c) Central nervous system stimulation d) Hyperglycaemia
Last Answer : c) Central nervous system stimulation
Description : __________ side effect is seen during the treatment with Levodopa a) Dyskinesias b) Bone marrow depression c) Thombocytopenia d) Impotence
Last Answer : a) Dyskinesias
Description : Which of the following is true of ‘placebos’: A. Placebo is a dummy medication B. Placebo is the inert material added to the drug for making tablets C. Placebos do not produce any effect D. All patients respond to placebos
Last Answer : A. Placebo is a dummy medication
Description : Choose the correct statement about topical NSAID preparations: A. They produce high drug levels in the blood by avoiding hepatic first pass metabolism B. They produce high drug levels in ... a strong placebo effect D. Interindividual variability in clinical response to these preparations is minimal
Last Answer : C. They elicit symptomatic relief in soft tissue rheumatism mainly by a strong placebo effect
Description : An immunologically mediated reaction to a drug producing stereotyped symptoms unrelated to its pharmacodynamic actions is: A. Hypersensitivity B. Supersensitivity C. Intolerance D. Idiosyncrasy
Last Answer : A. Hypersensitivity
Description : You are asked to compare the cost of four different antibacterial medicines. Which of the following treatment courses is the lowest cost? a) Medicine A costs £17.00 for 28 tablets. The adult dose is one ... 14 tablets. The adult dose is one tablet each day and the usual treatment duration is 5 days.
Last Answer : c) Medicine C costs £20.00 for 25 tablets. The adult dose is one tablet twice a day and the usual treatment duration is 5 days.
Description : GCP are seen in all of the following except a) Phase I trial b) Phase II trial c) Preclinical trials d) Phase IV trial
Last Answer : c) Preclinical trials
Description : Which of the following is Type B ADRS? a) Hypoglycaemia caused by Insulin b) Dryness of mouth caused by Atropine c) Anaemia in patient with G6PD deficiency caused by Primaquine d) Hyperglycaemia caused by thiazide diuretics
Last Answer : c) Anaemia in patient with G6PD deficiency caused by Primaquine
Description : Which of the following would you classify as a pharmacodynamics interaction? a) ACE inhibitors with potassium-sparing diuretics cause life-threatening hyperkalaemia b) Antacids reduce the absorption ... Increased bleeding due to cimetidine and warfarin d) Probenecid increases half-life of penicillin
Last Answer : a) ACE inhibitors with potassium-sparing diuretics cause life-threatening hyperkalaemia
Description : When tetracycline is given with antacids the absorption of tetracycline ----------------. a) Increases b) Decreases c) Minimally altered d) Not altered at all
Last Answer : b) Decreases
Description : Absorption of Griseofulvin increases with --------------diet. a) Carbohydrate b) Fatty c) protein d) vitamin
Last Answer : b) Fatty
Description : Gary baby syndrome occur in new born with a) Tetracycline b) Chloramphenicol c) Penicillin d) Erythromycin
Last Answer : b) Chloramphenicol
Description : Which of the following is a technique pharmacists can use to humanize themselves to their patients? a) Using the patient's preferred name in conversation b) Delegating as many tasks as possible to an ... the text of a medication bottle verbatim to a patient d) Providing business cards at the desk
Last Answer : c) Reading the text of a medication bottle verbatim to a patient