answer:Some major hills on 77 at the NC/Virginia line. Serious hills. Beautiful drive, but with a trailer, not much fun. The other thing is that 77 in WV is also quite hilly. Great scenery, good road, but lots of hills. And a couple of tunnels. 77 has fewer hotels in NC and WV; just not as busy a route. I’d do the 75 option. There are some hills, of course, but not as bad as on 77. Don’t get to Columbus around rush hour – 675 is a bear at that point.