The function of fibroblasts is to

The function of fibroblasts is to
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Answer :

secrete and maintain fibres.
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Which of the following statements regarding fibroblasts and their function in wound healing are true? a. IL-1 has both inhibitory and promotional effects on fibroblast growth b. TNFa stimulates fibroblast collagen synthesis c. IL-1 and TNFa have opposite effects on the healing of bone d. In human clinical trials, EGF (epithelial growth factor) has been demonstrated to accelerate epidermal regeneration in cutaneous wounds

Description : Which of the following statements regarding fibroblasts and their function in wound healing are true? a. IL-1 has both inhibitory and promotional effects on fibroblast growth b. TNFa ... EGF (epithelial growth factor) has been demonstrated to accelerate epidermal regeneration in cutaneous wounds

Last Answer : Answer: a, d IL-1 appears to be important in the process of normal wound repair. IL-1 has been shown to stimulate skin fibroblast and keratinocyte growth, as well as ... that recombinant EGF enhances keratinocyte migration. EGF is also a potent chemoattractant for granulation tissue fibroblasts

Which of the following statement(s) describe the effects of aging on wound healing? a. A finer, more cosmetic scar might be expected b. In vitro studies demonstrate decreased proliferative potential of fibroblasts and epithelial cells c. Skin sutures should be left in for a longer period of time d. Wound infection occurs more frequently in elderly patients due to diminished ability to fight infection

Description : Which of the following statement(s) describe the effects of aging on wound healing? a. A finer, more cosmetic scar might be expected b. In vitro studies demonstrate decreased proliferative ... . Wound infection occurs more frequently in elderly patients due to diminished ability to fight infection

Last Answer : Answer: a, b, c There are important age-dependent aspects of wound healing. The elderly heal more slowly and with less scarring. There is a gradual attenuation of the inflammatory ... the sutures. There is no evidence to suggest that wound infections occur more commonly in elderly patients

Which of the following statement(s) is/are true concerning wound contraction? a. Wound contraction accounts for similar rates of reduction of wound size regardless of their location b. The fibroblast, at the cellular level, is the primary force driving wound contraction c. Excessive wound contraction, when occurring over a joint, may lead to disability d. Actin microfillaments are found in fibroblasts and may play a role in wound contracture

Description : Which of the following statement(s) is/are true concerning wound contraction? a. Wound contraction accounts for similar rates of reduction of wound size regardless of their location b. The fibroblast ... d. Actin microfillaments are found in fibroblasts and may play a role in wound contracture

Last Answer : Answer: b, c, d Wound contraction is an important event which contrasts healing open wounds and closed incisions. When open wounds contract, the surrounding skin is pulled over the open wound ... number in contracting wounds and are felt to play an active role in the process of wound contraction

Which of the following is/are true concerning wound fibroblasts? A. Fibroblasts synthesize and secrete collagen molecules. B. Wound fibroblasts are derived from blood-borne precursor cells. C. Fibroblasts migrate to a wound along fibrin strands, which are used as a scaffold. D. Large amounts of fibrin or blood clot can act as a physical barrier to fibroblast penetration, which delays normal wound healing.

Description : Which of the following is/are true concerning wound fibroblasts? A. Fibroblasts synthesize and secrete collagen molecules. B. Wound fibroblasts are derived from blood-borne precursor cells. C. ... clot can act as a physical barrier to fibroblast penetration, which delays normal wound healing.

Last Answer : Answer: ACD DISCUSSION: Fibroblasts appear in the wound on about the third day of healing and begin to synthesize and secrete collagen molecules. Wound fibroblasts arrive from cells surrounding ... enzymes, and large amounts of fibrin and blood clot prevent fibroblasts from entering the wound

Which of the following is/are true of the actions of transforming growth factor beta (TGF-b) during wound repair? A. Increased matrix and proteoglycan synthesis. B. Inhibition of proteases. C. Stimulation of plasminogen inhibitor. D. Chemotaxis for fibroblasts and macrophages. E. Autoinduction of TGF-b.

Description : Which of the following is/are true of the actions of transforming growth factor beta (TGF-b) during wound repair? A. Increased matrix and proteoglycan synthesis. B. Inhibition of proteases. ... of plasminogen inhibitor. D. Chemotaxis for fibroblasts and macrophages. E. Autoinduction of TGF-b.

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Leukotrienes: 1) Are formed from the cyclooxygenase pathway 2) Are synthesized by fibroblasts 3) Decrease vascular permeability 4) Leukotriene D4 has been identified as SRS-A which causes bronchial wall smooth muscle relaxation 5) Stimulate mucus secretion

Description : Leukotrienes: 1) Are formed from the cyclooxygenase pathway 2) Are synthesized by fibroblasts 3) Decrease vascular permeability 4) Leukotriene D4 has been identified as SRS-A which causes bronchial wall smooth muscle relaxation 5) Stimulate mucus secretion

Last Answer : Answers-5 Leukotrienes are synthesized by leucocytes.They are mediators of allergic reaction. They increase vascular permeability and attract neutrophils and eosinophils to inflammatory sites. ... stimulate mucus production, an important consideration in the pathophysiology of bronchial asthma.

A granuloma is C A. a small nodule of granulation tissue B. a tumour composed of granulocytes C. composed primarily of epithelioid cell, fibroblasts and lymphocytes D. None of these

Description : A granuloma is C A. a small nodule of granulation tissue B. a tumour composed of granulocytes C. composed primarily of epithelioid cell, fibroblasts and lymphocytes D. None of these

Last Answer : composed primarily of epithelioid cell, fibroblasts and lymphocytes

Tissue macrophages are derived from which one of the following? A. Resident activated fibroblasts B. Activated B lymphocytes C. Circulating monocytes D. Platelets

Description : Tissue macrophages are derived from which one of the following? A. Resident activated fibroblasts B. Activated B lymphocytes C. Circulating monocytes D. Platelets

Last Answer : Platelets

Early granulation tissue is BEST characterized by the presence of: C A. Plasma cells and macrophages B. T lymphocytes and eosinophils C. Capillary buds and fibroblasts D. None of these

Description : Early granulation tissue is BEST characterized by the presence of: C A. Plasma cells and macrophages B. T lymphocytes and eosinophils C. Capillary buds and fibroblasts D. None of these

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Which one of the following are cardinal features of granulation tissue? C A. Abundant collagen B. Proliferating macrophages and lymphocytes C. Proliferating capillaries and fibroblasts D. None of these

Description : Which one of the following are cardinal features of granulation tissue? C A. Abundant collagen B. Proliferating macrophages and lymphocytes C. Proliferating capillaries and fibroblasts D. None of these

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A metastatic cancerous tumour is termed ‘sarcoma’ if the disorder is in (a) fibroblasts (b) circulatory system (c) immune system (d) epithelial cells.

Description : A metastatic cancerous tumour is termed ‘sarcoma’ if the disorder is in (a) fibroblasts (b) circulatory system (c) immune system (d) epithelial cells.

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Cortisol: a. increases the circulating lymphocytes b. increases the circulating eosinophils c. decreases the production of prostaglandins d. inhibits the production of fibroblasts

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With regard to interferons: a. they are produced by B lymphocytes b. IFN-gamma is produced by cells infected with virus c. IFN-gamma increases MCH class I and II expression in antigen presenting cell d. IFN-gamma is produced by fibroblasts

Description : With regard to interferons: a. they are produced by B lymphocytes b. IFN-gamma is produced by cells infected with virus c. IFN-gamma increases MCH class I and II expression in antigen presenting cell d. IFN-gamma is produced by fibroblasts

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Microfilaments may assist a. in the movement of fibroblasts in heart b. growth of axons c. contraction of all muscle d. all

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In mammals, histamine is secreted by (a) lymphocytes (b) mast cells (c) fibroblasts (d) histiocytes.

Description : In mammals, histamine is secreted by (a) lymphocytes (b) mast cells (c) fibroblasts (d) histiocytes.

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