Description : The 4 rate limiting enzymes of gluconeogenesis are (A) Glucokinase, Pyruvate carboxylae phosphoenol pyruvate carboxykinase and glucose-6-phosphatase (B) Pyruvate carboxylase, phosphoenol ... fructokinase, pyruvate carboxylase, phosphoenol pyruvate carboxykinase and fructose 1, 6 diphosphatase
Last Answer : B
Description : Glucose-6-phosphate is an allosteric inhibitor of (A) Glucokinase (B) Hexokinase (C) Phosphohexose isomerase (D) None of these
Last Answer : Answer : B
Description : During fasting, glucose is phosphorylated mainly by (A) Hexokinase (B) Glucokinase (C) Both (A) and (B) (D) None of these
Last Answer : Answer : A
Description : At low blood glucose concentration, brain but not liver will take up glucose. It is due to the (A) Low Km of hexokinase (B) Low Km of glucokinase (C) Specificity of glucokinase (D) Blood brain barrier
Description : The enzymes involved in Phosphorylation of glucose to glucose 6- phosphate are (A) Hexokinase (B) Glucokinase (C) Phosphofructokinase (D) Both (A) and (B)
Last Answer : D
Description : Conversion of glucose to glucose-6- phosphate in human liver is by (A) Hexokinase only (B) Glucokinase only (C) Hexokinase and glucokinase (D) Glucose-6-phosphate dehydrogenase
Last Answer : C
Description : Fructose 2, 3 bi phosphate is a powerful allosteric activator of (A) Fructose 1, 6 diphosphatase (B) Phosphofructokinase (C) Hexokinase (D) Fructokinase
Description : Conversion of fructose to sorbitol is catalysed by the enzyme: (A) Sorbitol dehydrogenase (B) Aldose reductase (C) Fructokinase (D) Hexokinase
Description : Insulin decreases the synthesis of (A) Hexokinase (B) Glucokinase (C) PEP carboxykinase (D) Glycogen synthetase
Last Answer : Answer : C
Description : ATP is a co-substrate as well as an allosteric inhibitor of (A) Phosphofructokinase (B) Hexokinase (C) Glucokinase (D) None of these
Description : A specific fructokinase present in liver has a very high affinity for its substrate because (A) Km for fructose is very high (B) Km for fructose is very low (C) Activity is affected by fasting (D) Activity is affected by insulin
Description : Glucokinase (A) Is widely distributed and occurs in most mammalian tissues (B) Has a high km for glucose and hence is important in the phosphorylation of glucose primarily after ingestion of a carbohydrate rich meal (C) Is widely distributed in Prokaryotes (D) None of these
Description : Glycogen synthetase activity is depressed by (A) Glucose (B) Insulin (C) Cyclic AMP (D) Fructokinase
Description : Glucocorticoids increase the synthesis of all of the following except (A) Glucokinase (B) Glucose-6-phosphatase (C) Fructose-1, 6-biphosphatase (D) Pyruvate carboxylase
Description : Hexokinase (Glucose + ATP → Glucose-6– P + ADP) belongs to the category: (A) Transferases (B) Lysases (C) Oxidoreductases (D) Isomerases
Description : The enzyme that converts glucose to glucose-6-phosphate is (A) Phosphatase (B) Hexokinase (C) Phosphorylase (D) Glucose synthetase
Description : The hexose monophosphate pathway includes the enzyme: (A) Maltase dehydrogenase (B) Hexokinase (C) α-Ketoglutarate dehydrogenase (D) Glucose-6-phosphate dehydrogenase
Last Answer : Answer : D
Description : Hexokinase is inhibited in an allosteric manner by (A) Glucose-6-Phosphate (B) Glucose-1-Phosphate (C) Fructose-6-phosphate (D) Fructose-1, 6-biphosphate
Description : The “Primaquin sensitivity types of haemolytic anaemia has been found to relate to reduced R.B.C activity of which enzyme? (A) Pyruvate kinase deficiency (B) Glucose-6-phosphatase deficiency (C) Glucose-6-p dehydrogenase deficiency (D) Hexokinase deficiency
Description : Which of the following is not an enzyme involved in glycolysis? (A) Euolase (B) Aldolose (C) Hexokinase (D) Glucose oxidase
Description : The best known cause of galactosemia is the deficiency of (A) Galactose 1-phosphate and uridyl transferase (B) Phosphoglucomutase (C) Galactokinase (D) Lactose synthase
Description : Galactose is phosphorylated by galactokinase to form (A) Galactose-6-phosphate (B) Galactose-1, 6 diphosphate (C) Galactose-1-phosphate (D) All of these
Description : An example of competitive inhibition of an enzyme is the inhibition of a. Succinic dehydrogenase by malonic acid b. Cytochrome oxidase by cyanide c. Hexokinase by glucose-6-phosphate d. Carbonic anhydrase by carbon dioxide
Last Answer : Ans: A
Description : Conversion of glucose to glucose-6-phosphate, the first irreversible reaction of glycolysis, is catalysed by (a) phosphofructokinase (b) aldolase (c) hexokinase (d) enolase.
Last Answer : (c) hexokinase
Description : Essential fructosuria is characterized by the lack of the hepatic enzyme: (A) Phosphohexose isomerase (B) Aldalose A (C) Aldolase B (D) Fructokinase
Description : Hereditary fructose intolerance involves the absence of the enzyme: (A) Aldalose B (B) Fructokinase (C) Triokinase (D) Phosphotriose isomerase
Description : Insulin has no effect on the activity of the enzyme: (A) Glycogen synthetase (B) Fructokinase (C) Pyruvate kinase (D) Pyruvate dehydrogenase
Description : During glycolysis, Fructose 1, 6 diphosphate is decomposed by the enzyme: (A) Enolase a (B) Fructokinase (C) Aldolase (D) Diphosphofructophosphatose
Description : Fructokinase catalyses which reaction?
Last Answer : Fructose to fructose-1-phosphate.
Description : What is the importance of phospho fructokinase?
Last Answer : It is the key enzyme (rate limiting enzyme) of the pathway. It is an irreversible reaction.
Description : A gluconeogenic enzyme among the following is (A) Phosphofructokinase (B) Pyruvate kinase (C) Phosphoenol pyruvate carboxykinase (D) Glucokinase
Description : Glucokinase is found in (A) Muscles (B) Brain (C) Liver (D) All of these
Description : One of the causes of hemolytic jaundice is (A) G-6 phosphatase deficiency (B) Increased conjugated bilirubin (C) Glucokinase deficiency (D) Phosphoglucomutase deficiency
Description : Synthesis of the following enzymes is increased during starvation. (A) Digestive enzymes (B) Gluconeogenic enzymes (C) Urea cycle enzymes (D) Glucokinase
Description : What is glucokinase?
Last Answer : The reaction is similar to hexokinase. But glucokinase is present only in liver, acts specifically on glucose, and is active when glucose level in blood is increased after a food.
Description : The enzymes present in the membrane of mitochondria are (A) Flavoproteins and cytochromes (B) Fumarase and lipase (C) Enolase and catalase (D) Hexokinase and zymase
Description : An example of feedback inhibition is (A) Allosteric inhibition of hexokinase by glucose6-phosphate (B) Cyanide action on cytochrome (C) Sulpha drug on folic acid synthesizer bacteria (D) Reaction between succinic dehydrogenase and succinic acid
Description : The enzyme hexokinase is a (A) Hydrolase (B) Oxidoreductase (C) Transferase (D) Ligase
Description : Which of the following is a substratespecific enzyme? (A) Hexokinase (B) Thiokinase (C) Lactase (D) Aminopeptidase
Description : An enzyme involved in gluconeogenesis is (A) Pyruvate kinase (B) Pyruvate carboxylase (C) Hexokinase (D) Phosphohexose isomerase
Description : The enzyme of the glycolic pathway, sensitive to inhibiton by fluoride ions is (A) Hexokinase (B) Aldolase (C) Enolase (D) Pyruvate kinase
Description : Example of an extracellular enzyme is (A) Lactate dehydrogenase (B) Cytochrome oxidase (C) Pancreatic lipase (D) Hexokinase
Description : The glycolysis is regulated by (A) Hexokinase (B) Phosphofructokinase (C) Pyruvate kinase (D) All of these
Description : Which one of the following is a rate limiting enzyme of gluconeogenesis? (A) Hexokinase (B) Phsophofructokinase (C) Pyruvate carboxylase (D) Pyruvate kinase
Description : What is hexokinase?
Last Answer : Hexokinase is the first step in the glycolysis pathway. It phosphorylates glucose to glucose-6-phosphate.
Description : Albinism is a congenital disorder resulting from the lack of which enzyme? (a) Tyrosinase (b) Xanthine oxidase (c) Catalase (d) Fructokinase
Last Answer : (a) Tyrosinase
Description : 2, 3-Biphosphoglycerate in high concentrations, combines with hemoglobin, causes (A) Displacement of the oxyhemoglobin dissociation curve to the left (B) Displacement of the oxyhemoglobin dissociation curve ... (C) No change in oxy hemoglobin dissociation curve (D) Increased affinity for oxygen
Description : The technique for purification of proteins that can be made specific for a given protein is (A) Gel filtration chromotography (B) Ion exchange chromatography (C) Electrophoresis (D) Affinity chromatography
Description : Give an example of affinity chromatography.
Last Answer : Separation and quantitation of glycated hemoglobin.
Description : Give the principle of affinity chromatography.
Last Answer : The technique is based on the high affinity of specific proteins for specific chemical groups.