Description : At low blood glucose concentration, brain but not liver will take up glucose. It is due to the (A) Low Km of hexokinase (B) Low Km of glucokinase (C) Specificity of glucokinase (D) Blood brain barrier
Last Answer : Answer : A
Description : Conversion of glucose to glucose-6- phosphate in human liver is by (A) Hexokinase only (B) Glucokinase only (C) Hexokinase and glucokinase (D) Glucose-6-phosphate dehydrogenase
Last Answer : C
Description : In the normal resting state of human most of the blood glucose burnt as fuel is consumed by (A) Liver (B) Brain (C) Adipose tissue (D) Muscles
Last Answer : Answer : B
Description : Gluconeogenesis does not occur in (A) Brain (B) Kidneys (C) Muscles (D) Liver
Last Answer : Answer : C
Description : Glucose-1-phosphate liberated from glycogen cannot be converted into free glucose in (A) Liver (B) Kidneys (C) Muscles (D) Brain
Description : Rapoport-Luebering cycle is located in (A) Liver (B) Muscles (C) Brain (D) Erythrocytes
Last Answer : Answer : D
Description : Creatine kinase is present in all of the following except (A) Liver (B) Myocardium (C) Muscles (D) Brain
Description : Ketone bodies are synthesized from fatty acid oxidation products by which of the following organs? (A) Liver (B) Skeletal muscles (C) Kidney (D) Brain
Description : α-Oxidation of fatty acids occurs mainly in (A) Liver (B) Brain (C) Muscles (D) Adipose tissue
Description : Lipid stores are mainly present in (A) Liver (B) Brain (C) Muscles (D) Adipose tissue
Description : Ketone bodies are synthesized in (A) Adipose tissue (B) Liver (C) Muscles (D) Brain
Description : The major site of urea synthesis is (A) Brain (B) Kidneys (C) Liver (D) Muscles
Description : Glucocorticoids increase the synthesis of all of the following except (A) Glucokinase (B) Glucose-6-phosphatase (C) Fructose-1, 6-biphosphatase (D) Pyruvate carboxylase
Description : Insulin decreases the synthesis of (A) Hexokinase (B) Glucokinase (C) PEP carboxykinase (D) Glycogen synthetase
Description : A gluconeogenic enzyme among the following is (A) Phosphofructokinase (B) Pyruvate kinase (C) Phosphoenol pyruvate carboxykinase (D) Glucokinase
Description : ATP is a co-substrate as well as an allosteric inhibitor of (A) Phosphofructokinase (B) Hexokinase (C) Glucokinase (D) None of these
Description : Glucose-6-phosphate is an allosteric inhibitor of (A) Glucokinase (B) Hexokinase (C) Phosphohexose isomerase (D) None of these
Description : During fasting, glucose is phosphorylated mainly by (A) Hexokinase (B) Glucokinase (C) Both (A) and (B) (D) None of these
Description : One of the causes of hemolytic jaundice is (A) G-6 phosphatase deficiency (B) Increased conjugated bilirubin (C) Glucokinase deficiency (D) Phosphoglucomutase deficiency
Description : Synthesis of the following enzymes is increased during starvation. (A) Digestive enzymes (B) Gluconeogenic enzymes (C) Urea cycle enzymes (D) Glucokinase
Description : Glucokinase (A) Is widely distributed and occurs in most mammalian tissues (B) Has a high km for glucose and hence is important in the phosphorylation of glucose primarily after ingestion of a carbohydrate rich meal (C) Is widely distributed in Prokaryotes (D) None of these
Last Answer : B
Description : The enzymes involved in Phosphorylation of glucose to glucose 6- phosphate are (A) Hexokinase (B) Glucokinase (C) Phosphofructokinase (D) Both (A) and (B)
Last Answer : D
Description : The 4 rate limiting enzymes of gluconeogenesis are (A) Glucokinase, Pyruvate carboxylae phosphoenol pyruvate carboxykinase and glucose-6-phosphatase (B) Pyruvate carboxylase, phosphoenol ... fructokinase, pyruvate carboxylase, phosphoenol pyruvate carboxykinase and fructose 1, 6 diphosphatase
Description : Hexokinase has a high affinity for glucose than (A) Fructokinase (B) Galactokinase (C) Glucokinase (D) All of the above
Description : What is glucokinase?
Last Answer : The reaction is similar to hexokinase. But glucokinase is present only in liver, acts specifically on glucose, and is active when glucose level in blood is increased after a food.
Description : Gangliosides are complex glycosphingolipids found in (A) Liver (B) Brain (C) Kidney (D) Muscle
Description : The hydrolysis of Glucose-6-phosphate is catalysed by a specific phosphatase which is found only in (A) Liver, intestines and kidneys (B) Brain, spleen and adrenals (C) Striated muscle (D) Plasma
Last Answer : A
Description : The maineffecting of glucagons is to increase (A) Glycolysis in muscles (B) Glycogenolysis in muscles (C) Glycogenolysis in liver (D) Glycogenesis in liver
Description : Esterification of cholesterol occurs mainly in (A) Adipose tissue (B) Liver (C) Muscles (D) Kidneys
Description : Ammonia is transported from muscles to liver mainly in the form of (A) Free ammonia (B) Glutamine (C) Asparagine (C) Alanine
Description : Cori’s cycle transfers (A) Glucose from muscles to liver (B) Lactate from muscles to liver (C) Lactate from liver to muscles (D) Pyruvate from liver to muscles
Description : Glucose-6-phosphatase is not present in (A) Liver and kidneys (B) Kidneys and muscles (C) Kidneys and adipose tissue (D) Muscles and adipose tissue
Description : Myelin sheaths are found: a) surrounding tendons b) covering the brain c) covering muscles d) around axons of neurons
Last Answer : ANSWER: D -- AROUND AXONS OF NEURONS
Description : Hyper insulinism can cause coma since (A) The chief nutrient for the brain is glucose (B) The chief nutrient for the heart is glucose (C) The glucostatic role of the liver is damaged (D) The kidneys are damaged
Description : In which diseases of the following organs, isoenzymes LDH-1 and LDH-2 will be released in plasma? (A) Kidney, R.B.C and Liver (B) Heart, Kidney and R.B.C (C) Heart, Kidney and Liver (D) Heart, Lungs and Brain
Description : Glycolysis is anaerobic in (A) Liver (B) Brain (C) Kidneys (D) Erythrocytes
Description : The structure which appears to be the only organ to add significant quantities of ketone bodies to the blood is (A) Brain (B) Erythrocytes (C) Liver (D) Skeletal muscle
Description : α-Oxidation i.e., the removal of one carbon at a time from the carboxyl end of the molecule has been detected in (A) Brain tissue (B) Liver (C) Adipose tissue (D) Intestine
Description : The enzyme glucose 6-phosphatase is present in (A) Liver (B) Muscle (C) Adipose tissue (D) Brain
Description : The sites for gluconeogenesis are (A) Liver and kidney (B) Skin and pancreas (C) Lung and brain (D) Intestine and lens of eye
Description : In the normal resting state of humans, most of the blood glucose burned as fuel is consumed by (A) Liver (B) Adipose tissue (C) Muscle (D) Brain
Description : LDH1 and LDH2 are elevated in (A) Myocardial infarction (B) Liver disease (C) Kidney disease (D) Brain disease
Description : Neutral fat is stored in (A) Liver (B) Pancreas (C) Adipose tissue (D) Brain
Description : Gangliosides are the glycolipids occurring in (A) Brain (B) Liver (C) Kidney (D) Muscle
Description : An organ which is extremely sensitive to ammonia toxicity is (A) Liver (B) Brain (C) Kidney (D) Heart
Description : Glycogen is present in all body tissues except (A) Liver (B) Brain (C) Kidney (D) Stomach
Description : The normal resting state of humans, most of the blood glucose burnt as “fuel” is consumed by (A) Liver (B) Brain (C) Kidneys (D) Adipose tissue
Description : The tissues with the highest total glycogen content are (A) Muscle and kidneys (B) Kidneys and liver (C) Liver and muscle (D) Brain and Liver
Description : During starvation, ketone bodies are used as a fuel by (A) Erythrocytes (B) Brain (C) Liver (D) All of these
Description : People consuming alcohol in heavy quantities generally die of – (1) liver or stomach cancer (2) weakening of heart muscles leading to cardiac arrest (3) blood cancer (4) Cirrhosis
Last Answer : (4) Cirrhosis Explanation: Cirrhosis is a condition in which the liver does not function properly due to longterm damage. This damage is characterized by the replacement of normal liver tissue by scar tissue.