DefinitionMononeuritis multiplex is a brain/nervous system (neurological) disorder that involves damage to at least two separate nerve areas.Alternative NamesMononeuropathy multiplex; Multifocal neuropathyCauses, incidence, and risk factorsMononeuritis multiplex is a form of damage to nerves outside the brain and spinal cord (peripheral neuropathy). It is a group of symptoms, not a disease. A part of the nerve cell called the axon is destroyed, which interferes with nerve signaling.The cause of mononeuritis multiplex affects nerves in many areas. As the disorder gets worse, the damage may become more widespread and affect more nerves. Common causes include:A lack of oxygen from decreased blood flowSwelling and irritation (inflammation) of blood vesselsNo cause is found in about a third of