Inflammation of the respiratory tract caused by the infection of Streptococcus microbe , rash infectious fever , inflammation of the tonsils or contagious rash of the middle ear are notable symptoms of rheumatism. The onset of the disease usually begins in childhood and affects many parts of the body , especially the heart. If the heart is not fully affected by this rage , the heart and the valves of the heart are often damaged. As a result, the heart is not able to pump blood properly and the amount of blood flow in the body decreases. If the rage is not caught in the beginning or if it is not treated properly then the outbreak of rage increases and then there is weight loss , anemia , fatigue , loss of appetite , pale complexion etc. and there is no way to ignore the presence of rage. Later, joint pain , swelling, and redness of the skin appear. If the disease is detected at an early stage, penicillin can be used properly to prevent the spread of the disease. Many physicians recommend regular use of penicillin in infected children until they reach adulthood.