Gram negative organisms are largely insensitive to
benzyl penicillin because:
A. They produce large quantities of penicillinase
B. They do not utilise D-alanine whose incorporation in the cell wall is inhibited by benzylpenicillin
C. Benzyl penicillin is not able to penetrate
deeper into the lipoprotein-peptidoglycan
multilayer cell wall of gram negative bacteria
D. Both ‘A’ and ‘B’ are correct
benzyl penicillin because:
A. They produce large quantities of penicillinase
B. They do not utilise D-alanine whose incorporation in the cell wall is inhibited by benzylpenicillin
C. Benzyl penicillin is not able to penetrate
deeper into the lipoprotein-peptidoglycan
multilayer cell wall of gram negative bacteria
D. Both ‘A’ and ‘B’ are correct