Description : Methylmalonyl CoA is a metabolite of (A) Valine (B) Leucine (C) Isoleucine (D) All of these
Last Answer : Answer : A
Description : A hydrocarbon formed in cholesterol synthesis is (A) Mevalonate (B) HMG CoA (C) Squalene (D) Zymosterol
Last Answer : Answer : C
Description : Which amino acid is a lipotropic factor? (A) Lysine (B) Lecuine (C) Tryptophan (D) Methionine
Last Answer : Answer : D
Description : Propionyl CoA is formed on oxidation of (A) Monounsaturated fatty acids (B) Polyunsaturated fatty acids (C) Fatty acids with odd number of carbon atoms (D) None of these FATS AND FATTY ACID METABOLISM 83
Description : Cholesterol by a feed back mechanism inhibits the activity of (A) HMG-CoA synthetase (B) HMG-CoA reductase (C) Thilase (D) Mevalonate kinase
Last Answer : Answer : B
Description : In the biosynthesis of cholesterol, the rate limiting enzyme is (A) Mevalonate kinase (B) HMG-CoA synthetase (C) HMG-CoA reductase (D) Cis-prenyl transferase
Description : In the biosynthesis of cholesterol, the step which controls the rate and locus of metabolic regulation is (A) Geranyl pyrophosphate farnesyl pyrophosphate (B) Squalene → lanosterol (C) HMG CoA → mevalonate (D) Lanosterol → 1, 4-desmethyl lanosterol
Description : The rage limiting step cholesterol biosynthesis is (A) Squalene synthetase (B) Mevalonate kinase (C) HMG CoA synthetase (D) HMG CoA reductase
Description : The ‘Committed step’ in the biosynthesis of cholesterol from acetyl CoA is (A) Formation of acetoacetyl CoA from acetyl CoA (B) Formation of mevalonate from HMG CoA (C) Formation of HMG CoA from acetyl CoA and acetoacetyl CoA (D) Formation of squalene by squalene synthetase
Description : An enzyme required for the synthesis of ketone bodies as well as cholesterol is (A) Acetyl CoA carboxylase (B) HMG CoA synthetase (C) HMG CoA reductase (D) HMG CoA lyase
Description : All statements regarding 3-OH-3 methyl glutaryl CoA are true except (A) It is formed in the cytoplasm (B) Required in ketogenesis (C) Involved in synthesis of Fatty acid (D) An intermediate in cholesterol biosynthesis
Description : Select the first line hypolipidemic drug/drugs for treating hypertriglyceridemia in a subject with normal cholesterol level: A. Fibrates B. HMG-CoA reductase inhibitors C. Nicotinic acid D. Both 'A' and 'C' are correc
Last Answer : D. Both 'A' and 'C' are correct
Description : Select the most appropriate hypolipidemic drug for a patient with raised LDL-cholesterol level but normal triglyceride level: A. A HMG-CoA reductase inhibitor B. A fibric acid derivative C. Gugulipid D. Nicotinic acid
Last Answer : A. A HMG-CoA reductase inhibitor
Description : Electrostatic bonds can be formed between the side chains of (A) Alanine and leucine (B) Leucine and valine (C) Asparate and glutamate (D) Lysine and aspartate
Description : Modern bread is formed with amino acid (a) Histidine (b) Lysine (c) Leucine (d) All
Last Answer : (d) All
Description : The acetyl CoA formed on β-oxidation of all long chain fatty acids is metabolized under normal circumstances to (A) CO2 and water (B) Cholesterol (C) Fatty acids (D) Ketone bodies
Description : Acetyl CoA formed from pyruvate can be used for the synthesis of all the following except (A) Glucose (B) Fatty acids (C) Cholesterol (D) Steroid hormones
Description : During each cycle of on going fatty acid oxidation, all the following compounds are generated except (A) H2O (B) Acetyl CoA (C) Fatty acyl CoA (D) NADH FATS AND FATTY ACID METABOLISM 103
Description : Which of the following metabolite integrates glucose and fatty acid metabolism? (A) Acetyl CoA (B) Pyruvate (C) Citrate (D) Lactate
Last Answer : A
Description : In the synthesis of Angiotensin I, rennin acts on Angiotensinogen and cleaves the (A) Leucine – leucine at 10 and 11 position (B) Valine – tyrosine at 3 and 4 position (C) Isoleucine – histidine at 5 and 6 position (D) Proline – histidine at 7 and 8 position
Description : Coenzyme A is required for catabolism of (A) Leucine (B) Isoleucine (C) Valine (D) All of these
Description : An important feature of maple syrup urine disease is (A) Patient can not be treated by dietary regulation (B) Without treatment death, of patient may occur by the end of second year of life (C) Blood levels of leucine, isoleucine and serine are increased (D) Excessive brain damage
Description : Carboxy peptidase B in the small intestine hydrolyzes peptides containing (A) Leucine (B) Isoleucine (C) Arginine (D) Cysteine
Description : All followings are ketogenic aminoacids except (A) Leucine (B) Isoleucine (C) Phenyl alanine (D) Glycine
Description : Branched chain amino acids are (A) Cysteine and cystine (B) Tyrosine and Tryptophan (C) Glycine and Serine (D) Valine, Leucine and Isoleucine
Description : All the following are branched chain amino acids except (A) Isoleucine (B) Alanine (C) Leucine (D) Valine
Description : Features of atorvastatin include the following: A. Dose to dose most potent HMG-CoA reductase inhibitor B. Higher ceiling of LDL-cholesterol lowering action than lovastatin C. Antioxidant property D. All of the above
Last Answer : D. All of the above
Description : Which amino acid is a lipotropic factor? (A) Lysine (B) Leucine (C) Tryptophan (D) Methionine
Description : Neutral amino acid is (A) Leucine (B) Lysine (C) Aspartic acid (D) Histidine
Description : One of the given example is an amino acid: (A) Oh-Lysine (B) Protein (C) Leucine (D) Serine
Description : The neutral amino acid is (A) Lysine (B) Proline (C) Leucine (D) Histidine
Description : The limiting amino acid in pulses is (A) Leucine (B) Lysine (C) Tryptophan (D) Methionine
Description : The limiting amino acid in wheat is (A) Leucine (B) Lysine (C) Cysteine (D) Methionine
Description : The activity of HMG-CoA reductase is inhibited by (A) A fungal inhibitor mevastatin (B) Probucol (C) Nicotinic acid (D) Clofibrate
Description : Acetyl CoA is not used for the synthesis of (A) Fatty acid (B) Cholesterol (C) Pyruvic acid (D) Citric acid
Last Answer : C
Description : The major source of cholesterol in arterial smooth muscle cells is from (A) IDL (B) LDL (C) HDL (D) Chylomicrons FATS AND FATTY ACID METABOLISM 101
Description : Cholesterol is excreted as such into ________. (A) Urine (B) Faeces (C) Bile (D) Tears FATS AND FATTY ACID METABOLISM 99
Description : Palmitic, oleic or stearic acid ester of cholesterol used in manufacture of cosmetic creams is (A) Elaidic oil (B) Lanoline (C) Spermaceti (D) Chaulmoogric oil FATS AND FATTY ACID METABOLISM 75
Description : Link between glycolysis, Krebs’ cycle and β-oxidation of fatty acid or carbohydrate and fat metabolism is (a) oxaloacetic acid (b) succinic acid (c) citric acid (d) acetyl CoA.
Last Answer : (d) acetyl CoA.
Description : Two amino groups are present in (A) Leucine (B) Glutamate (C) Lysine (D) Threonine
Description : Insulin decreases the activity of (A) cAMP dependent protein kinase (B) HMG CoA-reductas (C) Phosphodiesterase (D) Acetyl CoA-carboxylase
Description : HMG-CoA reductase activity is increased by administration of the hormone: (A) Insulin (B) Glucagon (C) Epinephrine (D) Glucocorticoids
Description : For reduction enzyme HMG-CoA reductase requires cofactor: (A) NADPH (B) NADP (C) NAD (D) FAD
Description : HMG-CoA is converted to mevalonate by reduction catalysed by (A) HMG-CoA synthetase (B) HMG-CoA reductase (C) Mevalonate kinase (D) Thiolase
Description : NAD is required as a coenzyme for (A) Malate dehydrogenase (B) Succinate dehydrogenase (C) Glucose-6-phosphate dehydrogenase (D) HMG CoA reductae
Description : Lovastatin is a (A) Competitive inhibitor of acetyl CoA carboxylase (B) Competitive inhibitor of HMG CoA synthetase (C) Non-competitive inhibitor of HMG CoA reductase (D) Competitive inhibitor of HMG CoA reductase
Description : What is HMG CoA synthase?
Last Answer : It is the rate-limiting-enzyme in ketogenesis pathway.
Description : Rice grain is deficient in (A) Lysine (B) Alanine (C) Glycine (D) Isoleucine
Last Answer : (A) Lysine
Description : The major fibrous proteins are: a) peptone and edestin b) glutelin and leucine c) valine and lysine d) myosin and actin
Last Answer : ANSWER: D -- Myosin and Actin