Description : Inosine monophophate is an intermediate during the de novo synthesis of (A) AMP and GMP (B) CMP and UMP (C) CMP and TMP (D) All of these
Last Answer : Answer : A
Description : The first pyrimidine nucleotide to be formed in de novo synthesis pathway is (A) UMP (B) CMP (C) CTP (D) TMP
Description : During de novo synthesis of pyrimidine nucleotides, the first ring compound to be formed is (A) Carbamoyl aspartic acid (B) Dihydro-orotic acid (C) Orotic acid (D) Orotidine monophosphate
Last Answer : Answer : B
Description : A purine nucleotide is (A) AMP (B) UMP (C) CMP (D) TMP
Description : A pyrimidine nucleotide is (A) GMP (B) AMP (C) CMP (D) IMP
Last Answer : Answer : C
Description : Tetrahydrofolate is required as a coenzyme for the synthesis of (A) UMP (B) CMP (C) TMP (D) All of these
Description : Amethopterin and aminopterin decrease the synthesis of (A) TMP (B) UMP (C) CMP (D) All of these
Description : PRPP glutamyl amidotransferase, the first enzyme uniquely committed to purine synthesis is feed back inhibited by (A) AMP (B) IMP (C) XMP (D) CMP
Description : De novo synthesis and oxidation of fatty acids differ in the following respect: (A) Synthesis occurs in cytosol and oxidation in mitochondria (B) Synthesis is decreased and oxidation increased by ... synthesis and FAD in oxidation (D) Malonyl CoA is formed during oxidation but not during synthesis
Description : In inherited deficiency of hypoxanthine guanine phosphoribosyl transferase (A) De novo synthesis of purine nucleotides is decreased (B) Salvage of purines is decreased (C) Salvage of purines is increased (D) Synthesis of uric acid is decreased
Description : All the following statements about primary gout are true except (A) Its inheritance is X-linked recessive (B) It can be due to increased activity of PRPP synthetase (C) It can be ... activity of hypoxanthine guanine phosphoribosyl transferase (D) De novo synthesis of purines is increased in it
Description : De novo synthesis of pyrimidine nucleotides is regulated by (A) Carbamoyl phosphate synthetase (B) Aspartate transcarbamoylase (C) Both (A) and (B) (D) None of these
Description : All the enzymes required for de novo synthesis of pyrimidine nucleotides are cytosolic except (A) Carbamoyl phosphate synthetase (B) Aspartate transcarbamoylase (C) Dihydro-orotase (D) Dihydro-orotate dehydrogenase
Last Answer : Answer : D
Description : An enzyme common to de novo synthesis of pyrimidine nucleotides and urea is (A) Urease (B) Carbamoyl phosphate synthetase (C) Aspartate transcarbamoylase (D) Argininosuccinase
Description : De novo synthesis of pyrimidine nucleotides occurs in (A) Mitochondria (B) Cytosol (C) Microsomes (D) Ribosomes
Description : The available PRPP is used preferentially for (A) De novo synthesis of purine nucleotides (B) De novo synthesis of pyrimidine nucleotides (C) Salvage of purine bases (D) Salvage of pyrimidine bases
Description : In the pathway of de novo synthesis of purine nucleotides, all the following are allosteric enzymes except (A) PRPP glutamyl amido transferase (B) Adenylosuccinate synthetase (C) IMP dehydrogenase (D) Adenylosuccinase
Description : For de novo synthesis of purine nucleotides, aspartate provides (A) Nitrogen 1 (B) Nitrogen 3 (C) Nitrogen 7 (D) Nitrogen 9
Description : For de novo synthesis of purine nucleotides, glycine provides (A) One nitrogen atom (B) One nitrogen and one carbon atom (C) Two carbon atoms (D) One nitrogen and two carbon atoms
Description : The nitrogen atoms for de novo synthesis of purine nucleotides are provided by (A) Aspartate and glutamate (B) Aspartate and glycine (C) Aspartate, glutamine and glycine (D) Aspartate, glutamate and glycine
Description : De novo synthesis of purine nucleotide occurs in (A) Mitochondria (B) Cytosol (C) Microsmes (D) Ribosomes
Description : Nucleotides required for the synthesis of nucleic acids can be obtained from (A) Dietary nucleic acids and nucleotides (B) De novo synthesis (C) Salvage of pre-existing bases and nucleosides (D) De novo synthesis and salvage
Description : All the following statements about acetyl CoA carboxylase are true except (A) It is required for de novo synthesis of fatty acids (B) It is required for mitochondrial elongation of fatty acids ( ... for microsomal elongation of fatty acids (D) Insulin converts its inactive form into its active form
Description : Formation of acetyl CoA from pyruvate for de novo synthesis of fatty acids requires (A) Pyruvate dehydrogenase complex (B) Citrate synthetase (C) ATP citrate lyase (D) All of these
Description : Acetyl CoA required for de novo synthesis of fatty acids is obtained from (A) Breakdown of existing fatty acids (B) Ketone bodies (C) Acetate (D) Pyruvate
Description : The maximum possible chain length of fatty acids formed in the pathway of de novo synthesis is (A) 16 Carbon atoms (B) 18 Carbon atoms (C) 20 Carbon atoms (D) 24 Carbon atoms
Description : C22 and C24, fatty acids required for the synthesis of sphingolipids in brain are formed by (A) De novo synthesis (B) Microsomal chain elongation (C) Mitochondrial chain elongation (D) All of these
Description : One functional sub-unit of multi-enzyme complex for de novo synthesis of fatty acids contains (A) One —SH group (B) Two —SH groups (C) Three —SH groups (D) Four —SH groups FATS AND FATTY ACID METABOLISM 87
Description : De novo synthesis of fatty acids is catalysed by a multi-enzyme complex which contains (A) One-SH group (B) Two-SH groups (C) Three-SH groups (D) Four-SH groups
Description : De novo synthesis of fatty acids requires all of the following except (A) Biotin (B) NADH (C) Panthothenic acid (D) ATP
Description : Acetyl CoA from mitochondria is transferred to cytoplasm for the de novo synthesis of fatty acid, by which enzyme?
Last Answer : ATP citrate lyase.
Description : What is the rate limiting enzyme of de novo synthesis of fatty acid?
Last Answer : Acetyl CoA carboxylase.
Description : Phosphofructokinase key enzyme in glycolysis is inhibited by (A) Citrate and ATP (B) AMP (C) ADP (D) TMP
Description : The pyrimidine nucleotide acting as the high energy intermediate is (A) ATP (B) UTP (C) UDPG (D) CMP
Description : All following are naturally occurring nucleotides except (A) Cyclic AMP (B) ATP (C) DNA (D) Inosine monophosphate
Description : The intermediate n hexose monophosphate shunt is (A) D-Ribulose (B) D-Arabinose (C) D-xylose (D) D-Lyxose
Last Answer : A
Description : The intermediate in hexose monophosphate shunt is (A) D-Ribolose (B) D-Arobinose (C) D-xylose (D) D-lyxose
Description : Enhanced facultative reabsorption of water by Vasopressin is mediated by (A) Cyclic AMP (B) Ca++ (C) Cyclic GMP (D) Mg++
Description : An allosteric inhibitor of IMP dehydrogenase is (A) AMP (B) ADP (C) GMP (D) GDP
Description : An allosteric inhibitor of adenylosuccinate synthetase is (A) AMP (B) ADP (C) GMP (D) GDP
Description : An allosteric inhibitor of PRPP glutamyl amido transferase is (A) AMP (B) ADP (C) GMP (D) All of these
Description : PRPP synthetase is allosterically inhibited by (A) AMP (B) ADP (C) GMP (D) All of these
Description : The catabolite repression is mediated by a catabolite gene activator protein (CAP) in conjunction with (A) AMP (B) GMP (C) cAMP (D) Cgmp
Description : Ring closure of formimidoimidazole carboxamide ribosyl-5-phosphate yields the first purine nucleotide: (A) AMP (B) IMP (C) XMP (D) GMP
Description : The second messenger for glucocorticoids is (A) Cyclic AMP (B) Cyclic GMP (C) Inositol triphosphate (D) No second messenger is required
Description : Second messenger for glucagons is (A) Cyclic AMP (B) Diacylglycerol (C) Cyclic GMP (D) Inositol triphosphate
Description : The second messenger for PTH is (A) Cyclic AMP (B) Cyclic GMP (C) Diacylglycerol (D) Inositol triphosphate
Description : Protein kinase C is activated by (A) Cyclic AMP (B) Cyclic GMP (C) Diacyl glycerol (D) Inositol triphosphate
Description : ACTH induces rise in (A) Cyclic AMP (B) Cyclic GMP (C) Calcium (D) Magnesium
Description : Allsoteric activator of glutamate dehydrogenase is (A) ATP (B) GTP (C) ADP and GDP (D) AMP and GMP