The best key to visit in The Florida Keys for a family vacation would definitely be Key West. Hands down, it offers the most variety as far as activities for families, which is essential for a family vacation. There are countless sightseeing tours including glass bottom boat rides and coral reef Scuba diving. Or, a more low-key and inexpensive activity such as fishing. They key also offers some of the best places to eat including the 7 Days Bakery & Deli and the Abbey Road Snack Shack. If you and your family are first-time visitors to the keys, definitely visit Key West. The countless activities and variety is sure to please you for the duration of your visit.