DefinitionGigantism is abnormally large growth due to an excess of growth hormoneduring childhood, before the bone growth plates have closed.Alternative NamesGiantismCauses, incidence, and risk factorsThe most common cause of too much growth hormone release is a noncancerous (benign) tumor of the pituitary gland. Other causes include:Carney complexMcCune-Albright syndrome (MAS)Multiple endocrine neoplasia type 1 (MEN-1)NeurofibromatosisIf excess growth hormone occurs after normal bone growth has stopped, the condition is known as acromegaly.Gigantism is very rare.SymptomsThe child will grow in height, as well as in the muscles and organs. This excessive growth makes the child extremely large for his or her age.Other symptoms include:Delayed pubertyDouble vision or difficulty with side (per