The division of the nucleus is called karyokinesis. And the division of cytoplasm is called cytokinesis. Stage five of karyokinesis. Step one of cytokinesis. Karyokinesis is completed slowly , cytokinesis is completed rapidly. Karyokinesis occurs before cell division and cytokinesis occurs later. In the case of karyokinesis, it occurs step by step without direct division of the nucleus. On the other hand, cytokinesis occurs directly in the cytoplasm.