answer:This is how I would do it: A) Review your HR handbook to see what you can take in terms of paid vacation, benefits etc. to see what you can leave with. B) Write up a classy letter of resignation, detailing how great this company has been to work for and how it has primed you to move forward with your education. Give one to your boss, and one copy for HR. Always leave on a high note. C) Start detailing your job duties so it's easy to train your replacement. Make it obvious that you have been thoughtful and highly detailed about the transition. D) Give as much time as possible. Two weeks is standard, of course, but three weeks makes you look incredibly gracious. Offer to take calls early in the transition. E) Don't criticize anyone or anything. Just leave keeping the whole tone of the resignation positive. F) Train the heck out of your replacement. Do everything you can to ensure they've got a good shot at succeeding. It's only fair to them. Even if we want to believe that the organization will fall down around itself if we leave, really, that's not the case ; ) If you cover at least all of these bases, you should be able to leave conflict-free.