answer:Yes. For the same reason inbred humans have more problems. The theory of hybrid vigor suggests that as a group, dogs of varied ancestry will be healthier than their purebred counterparts. In purebred dogs, intentionally breeding dogs of very similar appearance over several generations produces animals that carry many of the same alleles, some of which are detrimental. If the founding population for the breed was small, then the genetic diversity of that particular breed may be small for quite some time. Wiki