After a chemical neurotransmitter has been released from the synaptic terminal, its action must be terminated in some way. Otherwise, the continued presence of the transmitter in the extracellular space would continuously activate the post synaptic cell. The action of a neurotransmitter can be terminated in either of 2 ways: 1) The transmitter molecules are removed from the extracellular space by uptake into surrounding glial cells & neurons (including the presynaptic terminal that originally released the transmitter), as the neurotransmitter diffuses away from its site of release. 2) The neurotransmitter molecules are chemically degraded into inactive substances. At the neurotransmitter junction, this mechanism is used to inactivate Acetylcholine released from the synaptic terminals of the motor neurons.