What is the other term for suicide inhibition?

What is the other term for suicide inhibition?
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Mechanism based inactivation.
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Related questions

Give examples for suicide inhibition.

Description : Give examples for suicide inhibition.

Last Answer : Ornithine decarboxylase (ODC) is inhibited by difluro methyl ornithine (DFMO). Another example is Allopurinol which is oxidised by xanthine oxidase to alloxanthine that is a strong inhibitor of xanthine oxidase. 

What is suicide inhibition?

Description : What is suicide inhibition?

Last Answer : In suicide inhibition, the structural analogue is converted to a more effective inhibitor with the help of the enzyme to be inhibited. The inhibitor makes use of the enzymeís own reaction mechanism to inactivate it.

Suicide Hackers are those _________ a) who break a system for some specific purpose with or without keeping in mind that they may suffer long term imprisonment due to their malicious activity b) individuals with no knowledge of codes but an expert in using hacking tools c) who know the consequences of their hacking activities and hence try to prevent them by erasing their digital footprints d) who are employed in an organization to do malicious activities on other firms

Description : Suicide Hackers are those _________ a) who break a system for some specific purpose with or without keeping in mind that they may suffer long term imprisonment due to their malicious activity ... digital footprints d) who are employed in an organization to do malicious activities on other firms

Last Answer : a) who break a system for some specific purpose with or without keeping in mind that they may suffer long term imprisonment due to their malicious activity

One of the important functions of prostacyclins is (A) Inhibition of platelet aggregation (B) Contraction of uterus (C) Decrease of gastric secretion (D) Relieving osthma

Description : One of the important functions of prostacyclins is (A) Inhibition of platelet aggregation (B) Contraction of uterus (C) Decrease of gastric secretion (D) Relieving osthma

Last Answer : Answer : A

The blood sugar raising action of the hormone of suprarenal cortex is due to (A) Glyconeogenesis (B) Glycogenolysis (C) Glucagon like activity (D) due to inhibition of glomerular filtration of glucose

Description : The blood sugar raising action of the hormone of suprarenal cortex is due to (A) Glyconeogenesis (B) Glycogenolysis (C) Glucagon like activity (D) due to inhibition of glomerular filtration of glucose

Last Answer : Answer : A

Regulation of ACTH secretion occurs through (A) Corticotropin releasing hormone (CRH) and corticotropin release inhibiting hormone (CRIH) of hypothalamus (B) Feedback inhibition by cortisol (C) CRH and feedback inhibition by cortisol (D) CRIH and feedback inhibition by cortisol

Description : Regulation of ACTH secretion occurs through (A) Corticotropin releasing hormone (CRH) and corticotropin release inhibiting hormone (CRIH) of hypothalamus (B) Feedback inhibition by cortisol (C) CRH and feedback inhibition by cortisol (D) CRIH and feedback inhibition by cortisol

Last Answer : Answer : C

Secretion of prolactin is regulated by (A) Feedback inhibition (B) Prolactin releasing hormone (C) Prolactin release inhibiting hormone (D) All of these

Description : Secretion of prolactin is regulated by (A) Feedback inhibition (B) Prolactin releasing hormone (C) Prolactin release inhibiting hormone (D) All of these

Last Answer : Answer : C

Secretion of growth hormone is inhibited by (A) Somatomedin C (B) Somatostatin (C) Feedback inhibition(D) All of these

Description : Secretion of growth hormone is inhibited by (A) Somatomedin C (B) Somatostatin (C) Feedback inhibition(D) All of these

Last Answer : Answer : B

Down regulation is (A) Increased destruction of a hormone (B) Feed back inhibition of hormone secretion (C) Decreased concentration of a hormone in blood (D) Decrease in number of receptors for a hormone

Description : Down regulation is (A) Increased destruction of a hormone (B) Feed back inhibition of hormone secretion (C) Decreased concentration of a hormone in blood (D) Decrease in number of receptors for a hormone

Last Answer : Answer : D

Allosteric inhibition (A) Makes active site unifit for substrate (B) Controls excess formation and end product (C) Both (A) and (B) (D) None of these

Description : Allosteric inhibition (A) Makes active site unifit for substrate (B) Controls excess formation and end product (C) Both (A) and (B) (D) None of these

Last Answer : Answer : C

An example of feedback inhibition is (A) Allosteric inhibition of hexokinase by glucose6-phosphate (B) Cyanide action on cytochrome (C) Sulpha drug on folic acid synthesizer bacteria (D) Reaction between succinic dehydrogenase and succinic acid

Description : An example of feedback inhibition is (A) Allosteric inhibition of hexokinase by glucose6-phosphate (B) Cyanide action on cytochrome (C) Sulpha drug on folic acid synthesizer bacteria (D) Reaction between succinic dehydrogenase and succinic acid

Last Answer : Answer : A

Feedback inhibition of enzyme is influenced by (A) Enzyme (B) External factors (C) End product (D) Substrate

Description : Feedback inhibition of enzyme is influenced by (A) Enzyme (B) External factors (C) End product (D) Substrate

Last Answer : Answer : C

Enzyme inhibition caused by a substance resembling substrate molecule is (A) Competitive inhibition (B) Non-competitive inhibition (C) Feedback inhibition (D) Allosteric inhibition

Description : Enzyme inhibition caused by a substance resembling substrate molecule is (A) Competitive inhibition (B) Non-competitive inhibition (C) Feedback inhibition (D) Allosteric inhibition

Last Answer : Answer : A

Feedback inhibition of enzyme action is affected by (A) Enzyme (B) Substrate (C) End products (D) None of these

Description : Feedback inhibition of enzyme action is affected by (A) Enzyme (B) Substrate (C) End products (D) None of these

Last Answer : Answer : C

Which one of the following regulatory actions involves a reversible covalent modification of the enzyme? (A) Phosphorylation of ser-OH on the enzyme (B) Allosteric modulation (C) Competitive inhibition (D) Non-competitive inhibition

Description : Which one of the following regulatory actions involves a reversible covalent modification of the enzyme? (A) Phosphorylation of ser-OH on the enzyme (B) Allosteric modulation (C) Competitive inhibition (D) Non-competitive inhibition

Last Answer : Answer : A

In competitive inhibition which of the following kinetic effect is true ? (A) Decreases both Km and Vmax (B) Increases both Km and Vmax (C) Decreases Km without affecting Vmax (D) Increases Km without affecting Vmax

Description : In competitive inhibition which of the following kinetic effect is true ? (A) Decreases both Km and Vmax (B) Increases both Km and Vmax (C) Decreases Km without affecting Vmax (D) Increases Km without affecting Vmax

Last Answer : Answer : D

In competitive inhibition of enzyme action (A) The apparent Km is decreased (B) The apparent Km is increased (C) Vmax is decreased (D) Apparent concentration of enzyme molecules decreased

Description : In competitive inhibition of enzyme action (A) The apparent Km is decreased (B) The apparent Km is increased (C) Vmax is decreased (D) Apparent concentration of enzyme molecules decreased

Last Answer : Answer : B

Which of the following regulatory reactions involves a reversible covalent modification of an enzyme? (A) Phosphorylation of serine OH on the enzyme (B) Allosteric modulation (C) Competitive inhibition (D) Non-competitive inhibition

Description : Which of the following regulatory reactions involves a reversible covalent modification of an enzyme? (A) Phosphorylation of serine OH on the enzyme (B) Allosteric modulation (C) Competitive inhibition (D) Non-competitive inhibition

Last Answer : Answer : A

The inhibition of succinate dehydrogenase by malonate by (A) Competitive inhibition (B) Non-competitive inhibition (C) Uncompetitive inhibition (D) Feedback inhibition

Description : The inhibition of succinate dehydrogenase by malonate by (A) Competitive inhibition (B) Non-competitive inhibition (C) Uncompetitive inhibition (D) Feedback inhibition

Last Answer : Answer : A

Allosteric enzymes regulate the formation of products by (A) Feedback inhibition (B) Non-competitive inhibition (C) Competitive inhibition (D) Repression-derepression

Description : Allosteric enzymes regulate the formation of products by (A) Feedback inhibition (B) Non-competitive inhibition (C) Competitive inhibition (D) Repression-derepression

Last Answer : Answer : A

Competitive inhibition can be relieved by raising the (A) Enzyme concentration (B) Substrate concentration (C) Inhibitor concentration (D) None of these

Description : Competitive inhibition can be relieved by raising the (A) Enzyme concentration (B) Substrate concentration (C) Inhibitor concentration (D) None of these

Last Answer : Answer : B

In competitive inhibition, the inhibitor (A) Competes with the enzyme (B) Irreversibly binds with the enzyme (C) Binds with the substrate (D) Competes with the substrate

Description : In competitive inhibition, the inhibitor (A) Competes with the enzyme (B) Irreversibly binds with the enzyme (C) Binds with the substrate (D) Competes with the substrate

Last Answer : Answer : D

Allosteric inhibition is also known as (A) Competitive inhibition (B) Non-competitive inhibition (C) Feedback inhibition (D) None of these

Description : Allosteric inhibition is also known as (A) Competitive inhibition (B) Non-competitive inhibition (C) Feedback inhibition (D) None of these

Last Answer : Answer : C

An example of enzyme inhibition: (A) Reversible inhibition (B) Irreversible inhibition (C) Allosteric inhibition (D) All of these ENZYMES 151

Description : An example of enzyme inhibition: (A) Reversible inhibition (B) Irreversible inhibition (C) Allosteric inhibition (D) All of these ENZYMES 151

Last Answer : Answer : D

In non competitive enzyme activity inhibition, inhibitor (A) Increases Km (B) Decreases Km (C) Does not effect Km (D) Increases Km

Description : In non competitive enzyme activity inhibition, inhibitor (A) Increases Km (B) Decreases Km (C) Does not effect Km (D) Increases Km

Last Answer : Answer : C

In competitive enzyme activity inhibition (A) Apparent Km is decreased (B) Apparent Km is increased (C) Vmax is increased (D) Vmax is decreased

Description : In competitive enzyme activity inhibition (A) Apparent Km is decreased (B) Apparent Km is increased (C) Vmax is increased (D) Vmax is decreased

Last Answer : Answer : B

In competitive enzyme activity inhibition (A) The structure of inhibitor generally resembles that of the substrate (B) Inhibitor decreases apparent Km (C) Km remains unaffective (E) Inhibitor decreases Vmax without affecting Km

Description : In competitive enzyme activity inhibition (A) The structure of inhibitor generally resembles that of the substrate (B) Inhibitor decreases apparent Km (C) Km remains unaffective (E) Inhibitor decreases Vmax without affecting Km

Last Answer : Answer : A

In reversible non-competitive enzyme activity inhibition (A) Inhibitor bears structural resemblance to substrate (B) Inhibitor lowers the maximum velocity attainable with a given amount of enzyme (C) Km is increased (D) Km is decreased

Description : In reversible non-competitive enzyme activity inhibition (A) Inhibitor bears structural resemblance to substrate (B) Inhibitor lowers the maximum velocity attainable with a given amount of enzyme (C) Km is increased (D) Km is decreased

Last Answer : Answer : B

In reversible non-competitive enzyme activity inhibition (A) Vmax is increased (B) Km is increased (C) Km is decreased (D) Concentration of active enzyme is reduced

Description : In reversible non-competitive enzyme activity inhibition (A) Vmax is increased (B) Km is increased (C) Km is decreased (D) Concentration of active enzyme is reduced

Last Answer : Answer : D

If curve X in the graph (below) represents no inhibition for the reaction of the enzyme with its substrates, the curve representing the competitive inhibition, of the same reaction is (A) A (B) B (C) C (D) D

Description : If curve X in the graph (below) represents no inhibition for the reaction of the enzyme with its substrates, the curve representing the competitive inhibition, of the same reaction is (A) A (B) B (C) C (D) D

Last Answer : Answer : A

A sigmoidal plot of substrate concentration ([S]) verses reaction velocity (V) may indicate (A) Michaelis-Menten kinetics (B) Co-operative binding (C) Competitive inhibition (D) Non-competitive inhibition

Description : A sigmoidal plot of substrate concentration ([S]) verses reaction velocity (V) may indicate (A) Michaelis-Menten kinetics (B) Co-operative binding (C) Competitive inhibition (D) Non-competitive inhibition

Last Answer : Answer : B

The phenomenon of inhibition of glycolysis by O2 is termed as (A) Red drop (B) Pasteur effect (C) Michaelis effect (D) Fischer’s effect

Description : The phenomenon of inhibition of glycolysis by O2 is termed as (A) Red drop (B) Pasteur effect (C) Michaelis effect (D) Fischer’s effect

Last Answer : Answer : B

Secretin causes all of the following except (A) Secretion of pancreatic juice (B) Secretion of bile (C) Inhibition of gastric secretion (D) Stimulation of intestinal motility

Description : Secretin causes all of the following except (A) Secretion of pancreatic juice (B) Secretion of bile (C) Inhibition of gastric secretion (D) Stimulation of intestinal motility

Last Answer : Answer : D

The primary biochemical lesion in homozygote with familial hypercholesterolemia (type IIa) is (A) Loss of feed back inhibition of HMG reductase (B) Loss of apolipoprotein B (C) Increased production of LDL from VLDL (D) Functional deficiency of plasma membrane receptors for LDL

Description : The primary biochemical lesion in homozygote with familial hypercholesterolemia (type IIa) is (A) Loss of feed back inhibition of HMG reductase (B) Loss of apolipoprotein B (C) Increased production of LDL from VLDL (D) Functional deficiency of plasma membrane receptors for LDL

Last Answer : Answer : D

Pasteur effect is (A) Inhibition of glycolysis (B) Oxygen is involved (C) Inhibition of enzyme phosphofructokinase (D) All of these

Description : Pasteur effect is (A) Inhibition of glycolysis (B) Oxygen is involved (C) Inhibition of enzyme phosphofructokinase (D) All of these

Last Answer : D

The blood sugar raising action of the hormones of suprarenal cortex is due to (A) Gluconeogenesis (B) Glycogenolysis (C) Glucagon-like activity (D) Due to inhibition of glomerular filtration

Description : The blood sugar raising action of the hormones of suprarenal cortex is due to (A) Gluconeogenesis (B) Glycogenolysis (C) Glucagon-like activity (D) Due to inhibition of glomerular filtration

Last Answer : A

What is the importance of the above inhibition?

Description : What is the importance of the above inhibition?

Last Answer : Fluoride is used to prevent glycolysis, as preservative for blood before glucose estimation.

Give examples for allosteric inhibition.

Description :  Give examples for allosteric inhibition.

Last Answer : ALA synthase, aspartyl trans-carbamoylase, HMG CoA reductase

What are the salient features of allosteric inhibition?

Description : What are the salient features of allosteric inhibition?

Last Answer : (1) The inhibitor is not a substrate analogue. (2) It is partially reversible when excess substrate is added. (3) Km is usually increased. (4) Vmax is reduced. (5) Most allosteric enzymes possess quaternary structure. They are made up of subunits.

What is allosteric inhibition?

Description : What is allosteric inhibition?

Last Answer : Allosteric enzyme has one catalytic site where the substrate binds and another separate allosteric site where the modifier binds.

Give examples of non-competitive inhibition.

Description : Give examples of non-competitive inhibition.

Last Answer : Di-isopropyl fluoro phosphate inhibits trypsin, fluoride inhibits and enolase.

What are the salient features of non-competitive inhibition?

Description : What are the salient features of non-competitive inhibition? 

Last Answer : Non-competitive inhibitor has no structural similarity with the substrate. 2. It is generally not reversible 3. Km is not changed. 4. Vmax is reduced.

Give examples of clinical application of competitive inhibition.

Description : Give examples of clinical application of competitive inhibition. 

Last Answer : Sulfonamide inhibits PABA incorporation in bacteria, and so acts as an antibacterial agent. Methotrexate inhibits folate reductase system, dicoumarol inhibits vitamin K.

Give examples of competitive inhibition.

Description : Give examples of competitive inhibition.

Last Answer : Malonate inhibits succinate dehydrogenase.

What are salient features of competitive inhibition?

Description : What are salient features of competitive inhibition?

Last Answer : Competitive inhibitor is a structural analogue. 2. It is reversible. 3. Km is increased. 4. Vmax is not changed.

What is true of nimesulide: A. It exerts antiinflammatory action by several mechanisms in addition to cyclooxygenase inhibition B. It is preferred for long-term use in rheumatoid arthritis C. It is contraindicated in aspirin intolerant asthma patients D. All of the above

Description : What is true of nimesulide: A. It exerts antiinflammatory action by several mechanisms in addition to cyclooxygenase inhibition B. It is preferred for long-term use in rheumatoid arthritis C. It is contraindicated in aspirin intolerant asthma patients D. All of the above

Last Answer : A. It exerts antiinflammatory action by several mechanisms in addition to cyclooxygenase inhibition

A ’suicide enzyme’ is (A) Cycloxygenase (B) Lipooxygenase (C) Phospholipase A1 (D) Phospholipase A2

Description : A ’suicide enzyme’ is (A) Cycloxygenase (B) Lipooxygenase (C) Phospholipase A1 (D) Phospholipase A2

Last Answer : Answer : A

The cellular organelles called “suicide bags” are (A) Lysosomes (B) Ribosomes (C) Nucleolus (D) Golgi’s bodies

Description : The cellular organelles called “suicide bags” are (A) Lysosomes (B) Ribosomes (C) Nucleolus (D) Golgi’s bodies

Last Answer : A

Omeprazole exerts practically no other action except inhibition of gastric acid secretion because: A. It transforms into the active cationic forms only in the acidic pH of the gastric juice B. Its active forms have selective affinity for the H+K+ATPase located in the apical canaliculi of gastric parietal cells C. Its cationic forms are unable to diffuse out from the gastric parietal cell canaliculi D. All of the above

Description : Omeprazole exerts practically no other action except inhibition of gastric acid secretion because: A. It transforms into the active cationic forms only in the acidic pH of the gastric juice B. Its ... forms are unable to diffuse out from the gastric parietal cell canaliculi D. All of the above

Last Answer : D. All of the above

By emotional maturity is meant a Options: A) Low degree of sensitivity coupled with a high level of intellectual growth B) Extreme patience or sympathy towards problems involving other people C) Lack of patience or sympathy towards problem involving other people D) Lack of control or inhibition of the emotions appropriate to one's age-group

Description : By emotional maturity is meant a Options: A) Low degree of sensitivity coupled with a high level of intellectual growth B) Extreme patience or sympathy towards problems involving other people C) Lack of ... other people D) Lack of control or inhibition of the emotions appropriate to one's age-group

Last Answer : D) Lack of control or inhibition of the emotions appropriate to one's age-group