Regulation of ACTH secretion occurs through (A) Corticotropin releasing hormone (CRH) and corticotropin release inhibiting hormone (CRIH) of hypothalamus (B) Feedback inhibition by cortisol (C) CRH and feedback inhibition by cortisol (D) CRIH and feedback inhibition by cortisol

Regulation of ACTH secretion occurs through (A) Corticotropin releasing hormone (CRH) and corticotropin release inhibiting hormone (CRIH) of hypothalamus (B) Feedback inhibition by cortisol (C) CRH and feedback inhibition by cortisol (D) CRIH and feedback inhibition by cortisol
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Which is an example of negative feedback? A) Nursing action stimulates the hypothalamus to release oxytocin that triggers mammary gland milk production. B) When the blood becomes dilute, ADH is no longer released from the hypothalamus. C) Uterine stretching sends nerve impulses to the hypothalamus that releases oxytocin that triggers uterine contraction. D) FSH and LH stimulate the gonads to produce sperm or eggs. E) TRH stimulates the anterior pituitary to release thyroid-stimulating hormone.

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Which of the following structures or regions is incorrectly paired with its functions? (a) Medulla : Controls respiration oblongata and cardiovascular reflexes (b) Limbic : Consists of fibre tracts system that interconnect different regions of brain controls movement (c) Hypothalamus : Production of releasing hormones and regulation of temperature, hunger and thirst (d) Corpus callosum : Band of fibers connecting left and right cerebral hemispheres

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Increased reabsorption of water from the kidney is the major consequence of the secretion of the hormone? (A) Cortisol (B) Insulin (C) Vasopressin (D) Aldosterone

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Gastric Secretion is regulated by the hormone: (A) Glucagon (B) Gastrin (C) Epinephrin (D) ACTH

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Secretion of androgens is increased by (A) LH (B) FSH (C) ACTH (D) Growth hormone

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ACTH stimulates the secretion of (A) Glucocorticoids (B) Epinephrine (C) Thyroxine (D) Luteinizing hormone

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Last Answer : Answer : A

Antidiuretic hormone (A) Is secreted by hypothalamus (B) Secretion is increased when osmolality of plasma decreases (C) Increases obligatory reabsorption of water (D) Acts on distal convoluted tubules and collecting ducts

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In males, secretion of luteinising hormone is inhibited by (A) Gonadotropin releasing hormone (B) FSH (C) High blood level of testosterone (D) Inhibin

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All the following statements about FSH are true except (A) It is a tropic hormone secreted by anterior pituitary (B) Its secretion is increased by gonadotropin releasing hormone (C) It acts on Sertoli cells (D) It increases the synthesis of testosterone

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Secretion of somatotrophin is promoted by (A) Somatomedin C (B) Somatostatin (C) Growth hormone releasing hormone (D) Hypoglycaemia

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Which of the following hormones is not involved in carbohydrate metabolism? (A) Cortisol (B) ACTH (C) Glucogen (D) Vasopressin

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Last Answer : D

Which of the following techniques would be most useful in the differential diagnosis between ectopic Cushing's syndrome and pituitary dependent Cushing's disease. 1) Urine free cortisol 2) High dose Dexamethasone suppression test 3) ACTH concentrations 4) Inferior petrosal sinus sampling 5) CRF test

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Gene regulation governing lactose operon of E.coli that involves the lac I gene product is (a) negative and repressible because repressor protein prevents transcription (b) feedback inhibition because excess of β-galactosidase can switch off transcription (c) positive and inducible because it can be induced by lactose (d) negative and inducible because repressor protein prevents transcription.

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True statements about aldosterone include: a. secretion is mainly under the control of adrenocorticotrophic (ACTH) hormone secretion b. increases hepatic gluconeogenesis c. its secretion is stimulated by angiotensin d. in the kidney, mainly acts on the proximal convoluted tubules

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Streptomycin prevents synthesis of polypeptide by (A) Inhibiting initiation process (B) Releasing premature polypeptide (C) Inhibiting peptidyl transferase activity (D) Inhibiting translocation

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Last Answer : Answer : A

The following are true about the antidiuretic hormone: a. it is produced by the anterior pituitary gland b. it reduces the cardiac output c. it increases the renal absorption of sodium d. it decreases the release of ACTH

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A middle aged female presented with following symptoms - Hirsutism, fragility of skin, with easy bruising, broad purplish striae and signs of proximal myopathy. The first step in confirming the diagnosis will be Options: 1) Advice 24 hours urinary free cortisol excretion 2) Exclude exogenous Glucocorticoid use 3) Advice plasma ACTH estimation 4) Advice dexamethasone overnight test

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Last Answer : Correct Answer: 2) Exclude exogenous Glucocorticoid use

The hormone somatostatin is resposible for inhibiting the motility and absobtion in the digestive tract. It also inhibits the release of insuline and

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Secretion of mineralcorticoids is increased by (A) ACTH (B) Angiotensin (C) Hypokalaemia (D) Hypernatraemia

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Last Answer : Answer : B

Excessive secretion of ACTH causes (A) Cushing’s syndrome (B) Addison’s disease (C) Myxoedema (D) Thyrotoxicosis

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Last Answer : Answer : A

CRH is a polypeptide made up of (A) 39 amino acids (B) 41 amino acids (C) 51 amino acids (D) 84 amino acids

Description : CRH is a polypeptide made up of (A) 39 amino acids (B) 41 amino acids (C) 51 amino acids (D) 84 amino acids

Last Answer : Answer : B

Excessive secretion of glucocorticoids raises blood glucose by (A) Decreasing glycogenesis (B) Increasing glycogenolysis (C) Increasing gluconeogenesis (D) Inhibiting HMP shunt

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Last Answer : Answer : C

A high plasma calcium level decreases intestinal absorption of calcium by (A) Stimulating the secretion of parathormone (B) Inhibiting the secretion of parathormone (C) Decreasing the synthesis of cholecalciferol (D) Inhibiting the secretion of thyrocalcitonin

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