Which of the following in auto-mobile exhaust can cause cancer? (1) Oxides of nitrogen (2) Carbon monoxide (3) Lead (4) Polyclinic hydrocarbons

1 Answer

Answer :

(2) Carbon monoxide Explanation: Polycyclic aromatic hydrocarbons (PAHs) are formed during incomplete combustion. Domestic wood burning and road traffic are the major sources of PAHs. Exposure to PAH-containing substances increases the risk of cancer in humans. The carcinogenicity of PAHs is associated with the complexity of the molecule, i.e., increasing number of benzenoid 'rings, and with metabolic activation to reactive diol epoxide intermediates and their subsequent covalent binding to critical targets in DNA.

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