Description : ATP is required in following reactions of urea cycle: (A) Synthesis of carbamoyl phosphate and citrulline (B) Synthesis of citrulline and argininosuccinate (C) Synthesis of argininosuccinate and arginine (D) Synthesis of carbamoyl phosphate and argininosuccinate
Last Answer : Answer : C
Description : Cytosolic and mitochondrial carbamoyl phosphate synthetase have the following similarity: (A) Both use ammonia as a substance (B) Both provide carbamoyl phosphate for urea synthesis (C) Both require N-acetylglutamate as an activator (D) Both are allosteric enzymes
Description : An enzyme common to de novo synthesis of pyrimidine nucleotides and urea is (A) Urease (B) Carbamoyl phosphate synthetase (C) Aspartate transcarbamoylase (D) Argininosuccinase
Last Answer : Answer : B
Description : The enzymes of urea synthesis are found in (A) Mitochondria only (B) Cytosol only (C) Both mitochondria and cytosol (D) Nucleus
Description : De novo synthesis and oxidation of fatty acids differ in the following respect: (A) Synthesis occurs in cytosol and oxidation in mitochondria (B) Synthesis is decreased and oxidation increased by ... synthesis and FAD in oxidation (D) Malonyl CoA is formed during oxidation but not during synthesis
Last Answer : Answer : A
Description : All the enzymes required for de novo synthesis of pyrimidine nucleotides are cytosolic except (A) Carbamoyl phosphate synthetase (B) Aspartate transcarbamoylase (C) Dihydro-orotase (D) Dihydro-orotate dehydrogenase
Last Answer : Answer : D
Description : The metabolite which sustains urea cycle is (A) Ornithine (B) Citrulline (C) Carbamoyl phosphate (D) n-acetyl glutamate
Description : Control of urea cycle involves the enzyme: (A) Carbamoyl phosphate synthetase (B) Ornithine transcarbamoylase (C) Argininosuccinase (D) Arginase
Description : De novo synthesis of pyrimidine nucleotides is regulated by (A) Carbamoyl phosphate synthetase (B) Aspartate transcarbamoylase (C) Both (A) and (B) (D) None of these
Description : The biosynthesis of urea occurs mainly in the liver: (A) Cytosol (B) Mitochondria (C) Microsomes (D) Nuclei
Description : The biosynthesis of Urea occurs mainly in the Liver: (A) Cytosol (B) Microsomes (C) Nucleus (D) Mitochondria
Description : During synthesis of porphyrins, synthesis of δ-amino levulinic acid occurs in (A) Mitochondria (B) Cytosol (C) Both in mitochondria and cytosol (D) Ribosomes
Description : The synthesis of 3-hydroxy-3-methylglutaryl-CoA can occur (A) Only in mitochondria of all mammalian tissues (B) Only in the cytosol of all mammalian tissue (C) In both cytosol and mitochondria (D) In lysosomes
Description : The enzymes of the pentose phosphate pathway are found in the (A) Cytosol (B) Mitochondria (C) Nucleus (D) Endoplasmic reticulum
Description : De novo synthesis of pyrimidine nucleotides occurs in (A) Mitochondria (B) Cytosol (C) Microsomes (D) Ribosomes
Description : De novo synthesis of purine nucleotide occurs in (A) Mitochondria (B) Cytosol (C) Microsmes (D) Ribosomes
Description : All the enzymes involved in the synthesis of cholesterol are found in (A) Mitochondria (B) Golgi apparatus (C) Nucleus (D) Endoplasmic reticulum and cytosol
Description : The main pathway for denovo synthesis of fatty acids occur in (A) Cytosol (B) Mitochondria (C) Microsomes (D) Nucleus
Description : De hovo synthesis of fatty acids occurs in (A) Cytosol (B) Mitochondria (C) Microsomes (D) All of these
Description : During de novo synthesis of pyrimidine nucleotides, the first ring compound to be formed is (A) Carbamoyl aspartic acid (B) Dihydro-orotic acid (C) Orotic acid (D) Orotidine monophosphate
Description : Protein synthesis in an animal cell occurs (a) only on the ribosomes present in cytosol (b) only on ribosome attached to the nuclear envelope and endoplasmic reticulum (c) on ribosome present in the ... as well as in cytoplasm (d) on ribosomes present in cytoplasm as well as in mitochondria.
Last Answer : (d) on ribosomes present in cytoplasm as well as in mitochondria.
Description : .Protein synthesis in an animal cell occurs (a) only on the ribosomes present in cytosol (b) only on ribosome attached to the nuclear envelope and endoplasmic reticulum (c) on ribosome present in the ... as well as in cytoplasm (d) on ribosomes present in cytoplasm as well as in mitochondria.
Description : Which of the following ribosomes are engaged in protein synthesis in animal cell? (a) Ribosomes which occur on nuclear membrane and ER (b) Ribosomes of only cytosol (c) Ribosomes of only nucleolus and cytosol (d) Ribosomes of only mitochondria and cytosol
Last Answer : (a) poleward movement
Description : Which of the following contributes nitrogen atoms to both purine and pyrimidine rings? (A) Aspartate (B) Carbamoyl phosphate (C) CO2 (D) Glutamine
Description : In adipose tissue, glycerol-3-phosphate required for the synthesis of triglycerides comes mainly from (A) Hydrolysis of pre-existing triglycerides (B) Hydrolysis of phospholipids (C) Dihydroxyacetone phosphate formed in glycolysis (D) Free glycerol
Description : A key substance in the committed step of pyrimidines biosynthesis is (A) Ribose-5-phosphate (B) Carbamoyl phosphate (C) ATP (D) Glutamine
Description : Hyperammonaemia type I results from congenital absence of (A) Glutamate dehydrogenase (B) Carbamoyl phosphate synthetase (C) Ornithine transcarbamoylase (D) None of these
Description : Cytosolic carbamoyl phosphate synthetase is activated by (A) Glutamine (B) PRPP (C) ATP (D) Aspartate
Description : Cytosolic carbamoyl phosphate synthetase is inhibited by (A) UTP (B) CTP (C) PRPP (D) TMP
Description : Orotic aciduria type I reflects the deficiency of enzymes: (A) Orotate phosphoribosyl transferase and orotidylate decarboxylase (B) Dihydroorotate dehydrogenase (C) Dihydroorotase (D) Carbamoyl phosphate synthetase
Description : An enzyme of pyrimidine nucleotides biosynthesis regulated at the genetic level by apparently coordinate repression and derepression is (A) Carbamoyl phosphate synthetase (B) Dihydroorotate dehydrogenase (C) Thymidine kinase (D) Deoxycytidine kinase
Description : The two nitrogen of the pyrimidine ring are contributed by (A) Ammonia and glycine (B) Asparate and carbamoyl phosphate (C) Glutamine and ammonia (D) Aspartate and ammonia
Description : Pyrimidine biosynthesis begins with the formation from glutamine, ATP and CO2, of (A) Carbamoyl aspartate (B) Orotate (C) Carbamoyl phosphate (D) Dihydroorotate
Description : The highest energy level is present amongst the following in (A) 1, 3-Biphosphoglycerate (B) Creatine phosphate (C) Carbamoyl phosphate (D) Phosphoenol pyruvate
Description : An important finding in Hyperammonemia type II is (A) Increased serum gluatmine level (B) Enlarged liver (C) Mental retardation (D) Increased carbamoyl phosphate synthetase level
Description : Carbamoyl phosphate synthetase structure is marked by change in the presence of (A) N-Acetyl glutamate (B) N-Acetyl Aspartate (C) Neuraminic acid (D) Oxalate
Description : Transfer of the carbamoyl moiety of carbamoyl phosphate to ornithine is catalysed by a liver mitochondrial enzyme: (A) Carbamoyl phosphate synthetase (B) Ornithine transcarbamoylase (C) N-acetyl glutamate synthetase (D) N-acetyl glutamate hydrolase
Description : The enzyme carbamoyl phosphate synthetase requires (A) Mg++ (B) Ca++ (C) Na+ (D) K+
Description : Mammalian DNA polymerase γ is located in (A) Nucleus (B) Nucleolus (C) Mitochondria (D) Cytosol
Description : Porphyrins are synthesized in (A) Cytosol (B) Mitochondria (C) Cytosol and mitochondria (D) Rough endoplasmic reticulum
Description : The major site for elongation of medium chain fatty acids is (A) Mitochondria (B) Cytosol (C) Microsomes (D) All of these
Description : Glycolytic pathway is located in (A) Mitochondria (B) Cytosol (C) Microsomes (D) Nucleus
Description : Pyruvate dehydrogenase complex is located in (A) Cytosol (B) Lysosomes (C) Mitochondria (D) Endoplasmic reticulum
Description : Lactate dehydrogenase is located in (A) Lysosomes (B) Mitochondria (C) Cytosol (D) Microsomes
Description : The amino alcohol sphingosine is synthesized in (A) Mitochondria (B) Cytosol (C) Nucleus (D) Endoplasmic reticulum
Description : Acetyl-CoA is the principal building block of fatty acids. It is produced within the mitochondria and does not diffuse readily into cytosol. The availability of acetyl CoA involves (A) Carnitine acyl transferase (B) Pyruvate dehydrogenase (C) Citrate lyase (D) Thiolase
Description : The enzyme pyruvate carboxylase is present in (A) Cytosol (B) Mitochondria (C) Nucleus (D) Golgi bodies
Description : What is the sub cellular site for the βoxidation of fatty acids? (A) Nucleus (B) Mitochondria (C) Lysosome (D) Cytosol
Description : While citrate is converted to isocitrate in the mitochondria, it is converted to _______ in the cytosol. (A) Acetyl CoA + oxaloacetate (B) Acetyl CoA + malonyl CoA (C) Acetyl CoA + Pyruvate (D) Acetyl CoA + acetoacetyl CoA
Description : Oxidation of fatty acids occurs (A) In the cytosol (B) In the matrix of mitochondria (C) On inner mitochondrial membrane (D) On the microsomes