Description : Which of the following contributes nitrogen atoms to both purine and pyrimidine rings? (A) Aspartate (B) Carbamoyl phosphate (C) CO2 (D) Glutamine
Last Answer : Answer : A
Description : The four nitrogen atoms of purines are derived from (A) Urea and NH3 (B) NH3, Glycine and Glutamate (C) NH3, Asparate and Glutamate (D) Aspartate, Glutamine and Glycine
Last Answer : Answer : D
Description : Pyrimidine biosynthesis begins with the formation from glutamine, ATP and CO2, of (A) Carbamoyl aspartate (B) Orotate (C) Carbamoyl phosphate (D) Dihydroorotate
Last Answer : Answer : C
Description : The carbon atom at position 2 of pyrimidine nucleus is contributed by (A) CO2 (B) Glycine (C) Aspartate (D) Glutamine
Description : Two nitrogen of the pyrimidines ring are obtained from (A) Glutamine and Carbamoyl-p (B) Asparate and Carbamoyl-p (C) Glutamate and NH3 (D) Glutamine and NH3
Last Answer : Answer : B
Description : Nitrogen at position 3 of pyrimidine nucleus comes from (A) Glutamine (B) Glutamate (C) Glycine (D) Aspartate
Description : Nitrogen at position 1 of pyrimidine nucleus comes from (A) Glutamine (B) Glutamate (C) Glycine (D) Aspartate
Description : The 2 nitrogen atoms in urea are contributed by (A) Ammonia and glutamate (B) Glutamine and glutamate (C) Ammonia and aspartate (D) Ammonia and alanine
Description : The carbon atoms of pyrimidine nucleus are provided by (A) Glycine and aspartate (B) CO2 and aspartate (C) CO2 and glutamate (D) CO2 and glutamine
Description : Cytosolic carbamoyl phosphate synthetase is activated by (A) Glutamine (B) PRPP (C) ATP (D) Aspartate
Description : In the purine nucleus, carbon 6 is contributed by (A) Glycine (B) CO2 (C) Aspartate (D) Glutamine
Description : De novo synthesis of pyrimidine nucleotides is regulated by (A) Carbamoyl phosphate synthetase (B) Aspartate transcarbamoylase (C) Both (A) and (B) (D) None of these
Description : All the enzymes required for de novo synthesis of pyrimidine nucleotides are cytosolic except (A) Carbamoyl phosphate synthetase (B) Aspartate transcarbamoylase (C) Dihydro-orotase (D) Dihydro-orotate dehydrogenase
Description : An enzyme common to de novo synthesis of pyrimidine nucleotides and urea is (A) Urease (B) Carbamoyl phosphate synthetase (C) Aspartate transcarbamoylase (D) Argininosuccinase
Description : The nitrogen atoms of pyrimidine nucleus are provided by (A) Glutamate (B) Glutamate and aspartate (C) Glutamine (D) Glutamine and aspartate
Description : The nitrogen atoms for de novo synthesis of purine nucleotides are provided by (A) Aspartate and glutamate (B) Aspartate and glycine (C) Aspartate, glutamine and glycine (D) Aspartate, glutamate and glycine
Description : Which one of the following contributes nitrogen atoms to both purine and pyrimidine rings? (A) Aspartate (B) Carbanoyl phosphate (C) Carbondioxide (D) Tetrahydrofolate
Description : Carbamoyl phosphate synthetase structure is marked by change in the presence of (A) N-Acetyl glutamate (B) N-Acetyl Aspartate (C) Neuraminic acid (D) Oxalate
Description : A key substance in the committed step of pyrimidines biosynthesis is (A) Ribose-5-phosphate (B) Carbamoyl phosphate (C) ATP (D) Glutamine
Description : In purine biosynthesis carbon atoms at 4 and 5 position and N at 7 position are contributed by (A) Glycine (B) Glutamine (C) Alanine (D) Threonine
Description : An enzyme of pyrimidine nucleotides biosynthesis regulated at the genetic level by apparently coordinate repression and derepression is (A) Carbamoyl phosphate synthetase (B) Dihydroorotate dehydrogenase (C) Thymidine kinase (D) Deoxycytidine kinase
Description : In brain, the major metabolism for removal of ammonia is the formation of (A) Glutamate (B) Aspartate (C) Asparagine (D) Glutamine
Description : During de novo synthesis of pyrimidine nucleotides, the first ring compound to be formed is (A) Carbamoyl aspartic acid (B) Dihydro-orotic acid (C) Orotic acid (D) Orotidine monophosphate
Description : Electrostatic bonds can be formed between the side chains of (A) Alanine and leucine (B) Leucine and valine (C) Asparate and glutamate (D) Lysine and aspartate
Description : Cytosolic and mitochondrial carbamoyl phosphate synthetase have the following similarity: (A) Both use ammonia as a substance (B) Both provide carbamoyl phosphate for urea synthesis (C) Both require N-acetylglutamate as an activator (D) Both are allosteric enzymes
Description : In purine nucleus nitrogen atom at 1 position is derived from (A) Aspartate (B) Glutamate (C) Glycine (D) Alanine
Description : All of the following are required for synthesis of glutamine except (A) Glutamate (B) Ammonia (C) Pyridoxal phosphate (D) ATP
Description : The amino acid that undergoes oxidative deamination at significant rate is (A) Alanine (B) Aspartate (C) Glutamate (D) Glutamine
Description : Aspartate contributes the following carbon atoms of the pyrimidine nucelus: (A) C2 and C4 (B) C5 and C6 (C) C2, C4 and C6 (D) C4, C5 and C6
Description : The enzyme aspartate transcarbamoylase of pyrimidine biosynthesis is inhibited by (A) ATP (B) ADP (C) AMP (D) CTP
Description : An enzyme of pyrimidine nucleotide biosynthesis sensitive to allosteric regulation is (A) Aspartate transcarbamoylase (B) Dihydroorotase (C) Dihydroorotate dehydrogenase (D) Orotidylic acid decarboxylase
Description : Carnitine is synthesized from (A) Lysine and methionine (B) Glycine and arginine (C) Aspartate and glutamate (D) Proline and hydroxyproline
Description : Along with CO2, NH3 and ATP, the amino acid that is needed in urea cycle is (A) Alanine (B) Isoleucine (C) Aspartate (D) Glycine
Description : The primary structure of fibroin, the principal protein of silk worm fibres consists almost entirely of (A) Glycine (B) Aspartate (C) Keratin (D) Tryptophan
Description : The major source of NH3 produced by the kidney is (A) Leucine (B) Glycine (C) Alanine (D) Glutamine
Description : The amino acid which is not optically active is (A) Alanine (B) Glycine (C) Glutamine (D) Lysine
Description : Pyrimidine and purine nucleoside biosynthesis share a common precursor: (A) PRPP (B) Glycine (C) Fumarate (D) Alanine
Description : Hyperammonaemia type I results from congenital absence of (A) Glutamate dehydrogenase (B) Carbamoyl phosphate synthetase (C) Ornithine transcarbamoylase (D) None of these
Description : Cytosolic carbamoyl phosphate synthetase is inhibited by (A) UTP (B) CTP (C) PRPP (D) TMP
Description : Orotic aciduria type I reflects the deficiency of enzymes: (A) Orotate phosphoribosyl transferase and orotidylate decarboxylase (B) Dihydroorotate dehydrogenase (C) Dihydroorotase (D) Carbamoyl phosphate synthetase
Description : The highest energy level is present amongst the following in (A) 1, 3-Biphosphoglycerate (B) Creatine phosphate (C) Carbamoyl phosphate (D) Phosphoenol pyruvate
Description : An important finding in Hyperammonemia type II is (A) Increased serum gluatmine level (B) Enlarged liver (C) Mental retardation (D) Increased carbamoyl phosphate synthetase level
Description : The metabolite which sustains urea cycle is (A) Ornithine (B) Citrulline (C) Carbamoyl phosphate (D) n-acetyl glutamate
Description : ATP is required in following reactions of urea cycle: (A) Synthesis of carbamoyl phosphate and citrulline (B) Synthesis of citrulline and argininosuccinate (C) Synthesis of argininosuccinate and arginine (D) Synthesis of carbamoyl phosphate and argininosuccinate
Description : Carbamoyl phosphate required for urea synthesis is formed in (A) Cytosol (B) Mitochondria (C) Both (A) and (B) (D) None of these
Description : Transfer of the carbamoyl moiety of carbamoyl phosphate to ornithine is catalysed by a liver mitochondrial enzyme: (A) Carbamoyl phosphate synthetase (B) Ornithine transcarbamoylase (C) N-acetyl glutamate synthetase (D) N-acetyl glutamate hydrolase
Description : Control of urea cycle involves the enzyme: (A) Carbamoyl phosphate synthetase (B) Ornithine transcarbamoylase (C) Argininosuccinase (D) Arginase
Description : The enzyme carbamoyl phosphate synthetase requires (A) Mg++ (B) Ca++ (C) Na+ (D) K+
Description : A nucleotide is formed of (a) purine, pyrimidine and phosphate (b) purine, sugar and phosphate (c) nitrogen base, sugar and phosphate (d) pyrimidine, sugar and phosphate
Last Answer : (c) nitrogen base, sugar and phosphate
Description : Small amount of urinary oxalates is contributed by the amino acid: (A) Glycine (B) Tyrosine (C) Alanine (D) Serine