Description : The formation of citrate from oxalo acetate and acetyl CoA is (A) Oxidation (B) Reduction (C) Condensation (D) Hydrolysis CARBOHYDRATES AND CARBOHYDRATE METABOLISM 17
Last Answer : C
Description : The α-ketoacid is decarboxylated by H2O2 forming a carboxylic acid with one carbon atom less in the absence of the enzyme: (A) Catalase (B) Decarboxylase (C) Deaminase (D) Phosphatase
Last Answer : Answer : A
Description : An inborn error, maple syrup urine disease is due to deficiency of the enzyme: (A) Isovaleryl-CoAhydrogenase (B) Phenylalnine hydroxylase (C) Adenosyl transferase (D) α-Ketoacid decarboxylase
Last Answer : Answer : D
Description : Thiamin diphosphate is required for oxidative decarboxylation of (A) α-Keto acids (B) α-Amino acids (C) Fatty acids (D) All of these
Description : Fluoroacetate inhibits the reaction of citric acid cycle: (A) Isocitrate α-Ketoglutarate (B) Fumarate α-Malate (C) Citrate α-cis-aconitate (D) Succinate α-fumarate
Last Answer : Answer : C
Description : The example of generation of a high energy phosphate at the substrate level in the citric acid cycle is the reaction: (A) Isocitrate α-Ketoglutarate (B) Succinate α-fumarate (C) Malate α-oxaloacetate (D) Succinyl CoA α-Succinate
Description : Heme is synthesized from (A) Succinyl-CoA and glycine (B) Active acetate and glycine (C) Active succinate and alanine (D) Active acetate and alanine
Description : Pyruvic acid can be obtained by transamination of alanine with (A) α- keto glutaric acid (B) Acetoacetic acid (C) β−OH butyric acid (D) Phosphoenol Pyruvic acid
Description : Thiamine is essential for (A) Pyruvate dehydrogenase (B) Isocitrate dehydrogenase (C) Succinate dehydrogenase (D) Acetyl CoA synthetase ENZYMES 165
Last Answer : Answer : B
Description : In gluconeogensis, an allosteric activator required in the synthesis of oxaloacetate from bicarbonate and pyruvate, which is catalysed by the enzyme pyruvate carboxylase is (A) Acetyl CoA (B) Succinate (C) Isocitrate (D) Citrate
Description : NADPH is produced when this enzyme acts (A) Pyruvate dehydrogenase (B) Malic enzyme (C) Succinate dehydrogenase (D) Malate dehydrogenase
Description : An aneplerotic reaction which sustains the availability of oxaloacetate is the carboxylation of (A) Glutamate (B) Pyruvate (C) Citrate (D) Succinate
Last Answer : B
Description : Malonate is an inhibitor of (A) Malate dehydrogenase (B) α-Ketoglutarate dehydrogenase (C) Succinate dehydrogenase (D) Isocitrate dehydrogenase
Description : The reaction of Kreb’s cycle which does not require cofactor of vitamin B group is (A) Citrate isocitrate (B) α -Ketoglutarate succinate (C) Malate oxaloacetate (D) Succinate fumarate
Description : Dietary deficiency of thiamin inhibits the activity of the enzyme: (A) Pyruvate kinase (B) Pyruvate dehydrogenase (C) Phosphofructokinase (D) Enolase
Description : The initial step of the citric acid cycle is (A) Conversion of pyruvate to acetyl-CoA (B) Condensation of acetyl-CoA with oxaloacetate (C) Conversion of citrate to isocitrate (D) Formation of α -ketoglutarate catalysed by isocitrate dehydrogenase
Description : Lipoic acid is a conenzyme for (A) Pyruvate dehydrogenase (B) α-Ketoglutarate dehydrogenae (C) Both (A) and (B) (D) None of these
Description : Pyruvate dehydrogenase complex and α-ketoglutarate dehydrogenase complex require the following for their oxidative decarboxylation: (A) COASH and Lipoic acid (B) NAD+ and FAD (C) COASH and TPP (D) COASH, TPP,NAD+,FAD, Lipoate
Last Answer : D
Description : Aspartate amino transferase uses the following for transamination: (A) Glutamic acid and pyruvic acid (B) Glutamic acid and oxaloacetic acid (C) Aspartic acid and pyruvic acid (D) aspartic acid and keto adipic acid
Description : Acetyl CoA required for de novo synthesis of fatty acids is obtained from (A) Breakdown of existing fatty acids (B) Ketone bodies (C) Acetate (D) Pyruvate
Description : Decarboxylation of α-keto acids requires (A) Thiamine pyrophosphate, FAD, NAD+ (B) Flavin mononucleotide (C) NADP+ (D) NAD+ only
Description : α-D-glucose and β -D-glucose are (A) Stereoisomers (B) Epimers (C) Anomers (D) Keto-aldo pairs
Description : All of the following statements about aspartate are true except (A) It is non-essential amino acid (B) It is a dicarboxylic amino acid (C) It can be synthesized from pyruvate and glutamate (D) It can be converted into asparagine
Description : With the exception of glycine all amino acids found in protein are (A) Isocitrate dehydrogenase (B) Fumarase (C) Succinate thiokinase (D) ATPase
Description : Along with CO2, NH3 and ATP, the amino acid that is needed in urea cycle is (A) Alanine (B) Isoleucine (C) Aspartate (D) Glycine
Description : The first product of photosynthesis in C 3 plant is— (A) Pyruvic acid (B) Phospho-glyceric acid (C) Oxalo-acetic acid (D) Succinic acid
Last Answer : (B) Phospho-glyceric acid
Description : The immediate precursor for glumatic acid production by Corynebacterium glutamicumis A.lysine B.oxoacetate C.citrate D.2-oxo-glutarate
Last Answer : D.2-oxo-glutarate
Last Answer : .2-oxo-glutarate
Description : Which of the following enzyme defects is associated with a characteristic body odour? 1) Phenylalanine aminotransferase 2) Galactose0-phosphate-uridyltransferase 3) Ornithine transcarbamylase deficiency 4) Fumaryl acetoacetase 5) Branched chain ketoacid decarboxylase
Last Answer : Answers-5 The following inborn errors of amino acid metabolism are associated with abnormal odours: Glutaric acidaemia type II (sweaty feet), hawkinsinuria (swimming pool), isovaleric acidaemia (sweaty feet), ... The general rule is that if a child smells peculiar he requires a metabolic work-up.
Description : All of the following are required for synthesis of alanine except (A) Pyruvate (B) α-ketoglutarate (C) Glutamate (D) Pyridoxal phosphate
Description : Alanine can be synthesized from (A) Glutamate and α-ketoglutarate (B) Pyruvate and glutamate (C) Pyruvate and α-ketoglutarate (D) Asparate and α-ketoglutarate
Description : The amino acids abstracted from the liver are not utilized for repair or special synthesis but are broken down to (A) Keto acids (B) Sulphur dioxide (C) Water (D) Ammonia
Description : Claisen condensation gives__________ a) Hydroxyl compound b) β- keto ester c) Γ- diketone d) Α-diketone
Last Answer : b) β- keto ester
Description : Number of amino acids present in the dietary proteins: (A) 22 (B) 23 (C) 20 (D) 19
Description : The nucleophilic attack on the esterified carboxyl group of the peptidyl-tRNA occupying the P site and the α-amino group of the new amino acyl tRNA, the number of ATP required by the amino acid on the charged tRNA is (A) Zero (B) One (C) Two (D) Four
Description : In the biosynthesis of the iron protoporphyrin, the product of the condensation between succinyl-CoA and glycine is (A) α-Amino β-ketoadipic acid (B) δ-Aminolevulinate (C) Hydroxymethylbilane (D) Uroporphyrinogen I
Description : All of the following intermediates of citric acid cycle can be formed from amino acids except (A) α-Ketoglutarate (B) Fumarate (C) Malate (D) Oxaloacetate
Description : All α-amino acids have one asymmetric carbon atom except (A) Arginine (B) Glycine (C) Aspartic acid (D) Histidine
Description : An amino acid that does not take part in α helix formation is (A) Histidine (B) Tyrosine (C) Proline (D) Tryptophan
Description : Along the α-helix each amino acid residue advances in nm by (A) 0.15 (B) 0.10 (C) 0.12 (D) 0.20
Description : Each turn of α-helix contains the amino acid residues (number): (A) 3.6 (B) 3.0 (C) 4.2 (D) 4.5
Description : An example of α-amino acid not present in proteins but essential in mammalian metabolism is (A) 3-Amino 3-hydroxypropanoic acid (B) 2-Amino 3-hydroxybutanoic acid (C) 2-Amino 4-mercaptobutanoic acid (D) 2-Amino 3-mercaptopropanoic acid
Description : The group of micro-organisms involved in production of methane from acetic acid (or acetate) in anaerobic wastewater treatment process is : (a) Methodnotrix and Methanobacterium (b) Methanobacterium and Methanosarcina (c) Methanosarcina and Methanospirillum (d) Methanothrix and Methanosarcina
Last Answer : (d) Methanothrix and Methanosarcina
Description : An enzyme involved in gluconeogenesis is (A) Pyruvate kinase (B) Pyruvate carboxylase (C) Hexokinase (D) Phosphohexose isomerase
Description : The coenzyme not involved in the formation of acetyl-CoA from pyruvate is (A) TPP (B) Biotin (C) NAD (D) FAD
Description : In citric acid cycle, GDP is phosphorylated by (A) Succinate dehydrogenase (B) Aconitase (C) Succinate thiokinase (D) Fumarse
Description : Among citric acid cycle enzymes, a flavoprotein is (A) Malate (B) Fumarase (C) Succinate dehrogenase (D) Isocitrate dehrogenase
Description : For extramitochondrial fatty acid synthesis, acetyl CoA may be obtained from (A) Citrate (B) Isocitrate (C) Oxaloacetate (D) Succinate
Description : A compound serving a link between citric acid cycle and urea cycle is (A) Malate (B) Citrate (C) Succinate (D) Fumarate
Description : The carrier of the citric acid cycle is (A) Succinate (B) Fumarate (C) Malate (D) Oxaloacetate