Description : G-proteins have a nucleotide binding site for (A) ADP/ATP (B) GDP/GTP (C) CDP/CTP (D) UDP/UTP
Last Answer : Answer : B
Description : In the reaction below, Nu TP stands for NuTP + glucose → Glucose 6–Phosphate + NuDP. (A) ATP (B) CTP (C) GTP (D) UTP
Last Answer : Answer : A
Description : All of the following statements about thioredoxin reductase are true except: (A) It requires NADH as a coenzyme (B) Its substrates are ADP, GDP, CDP and UDP (C) It is activated by ATP (D) It is inhibited by dADP
Description : The reaction succinyl COA to succinate requires (A) CDP (B) ADP (C) GDP (D) NADP+
Last Answer : B
Description : In the synthesis of glycogen from glucose the reversible step is (A) Glucose → glucose 6-phosphate (B) Glucose 6-phosphate → glucose 1-phosphate (C) Glucose 1-phosphate → UDP glucose (D) UDP glucose → glycogen
Description : UDP Glucuronic acid is required for the biosynthesis of (A) Chondroitin sulphates (B) Glycogen (C) Lactose (D) Starch
Last Answer : A
Description : Hexokinase (Glucose + ATP → Glucose-6– P + ADP) belongs to the category: (A) Transferases (B) Lysases (C) Oxidoreductases (D) Isomerases
Last Answer : Answer : C
Description : Given that the standard free energy change (∆G°) for the hydrolysis of ATP is -7.3 K cal/mol and that for the hydrolysis of Glucose 6-phosphate is -3.3 Kcal/mol, the ∆G° for the phosphorylation of glucose is Glucose + ATP → ... -10.6 Kcal/mol (B) -7.3 Kcal/mol (C) -4.0 Kcal/mol (D) +4.0 Kcal/mol
Description : One of the following statement is correct: (A) Glycogen synthase ‘a’ is the phosphorylated (B) cAMP converts glycogen synthase b to ‘a’ (C) Insulin converts glycogen synthase b to a (D) UDP glucose molecules interact and grow into a Glycogen tree
Last Answer : C
Description : The enzyme aspartate transcarbamoylase of pyrimidine biosynthesis is inhibited by (A) ATP (B) ADP (C) AMP (D) CTP
Last Answer : Answer : D
Description : In purine biosynthesis ring closure in the molecule formyl glycinamide ribosyl-5- phosphate requires the cofactors: (A) ADP (B) NAD (C) FAD (D) ATP and Mg++
Description : UDP and UTP are formed by phosphorylation from (A) AMP (B) ADP (C) ATP (D) GTP
Description : UDPG is oxidized to UDP glucuronic acid by UDP dehydrogenase in presence of (A) FAD+ (B) NAD+ (C) NADP+ (D) ADP+
Description : An enzyme of pyrimidine nucleotide biosynthesis sensitive to allosteric regulation is (A) Aspartate transcarbamoylase (B) Dihydroorotase (C) Dihydroorotate dehydrogenase (D) Orotidylic acid decarboxylase
Description : A substrate for enzymes of pyrimidine nucleotide biosynthesis is (A) Allopurinol (B) Tetracylin (C) Chloramphenicol (D) Puromycin
Description : The major determinant of the overall rate of denovo purine nucleotide biosynthesis is the concentration of (A) 5-phosphoribosyl 1-pyrophosphate (B) 5-phospho β-D-ribosylamine (C) Glycinamide ribosyl-5-phosphate (D) Formylglycinamide ribosyl-5-phosphate
Description : In the biosynthesis of cholesterol, the step which controls the rate and locus of metabolic regulation is (A) Geranyl pyrophosphate farnesyl pyrophosphate (B) Squalene → lanosterol (C) HMG CoA → mevalonate (D) Lanosterol → 1, 4-desmethyl lanosterol
Description : An allosteric inhibitor of IMP dehydrogenase is (A) AMP (B) ADP (C) GMP (D) GDP
Description : An allosteric inhibitor of adenylosuccinate synthetase is (A) AMP (B) ADP (C) GMP (D) GDP
Description : The cofactors required for synthesis of adenylosuccinate are (A) ATP, Mg++ (B) ADP (C) GTP, Mg++ (D) GDP
Description : Coenzyme for phosphoenolpyruvate carboxykinase is (A) ATP (B) ADP (C) GTP (D) GDP
Description : Allsoteric activator of glutamate dehydrogenase is (A) ATP (B) GTP (C) ADP and GDP (D) AMP and GMP
Description : The mechanism of synthesis of DNA and RNA are similar in all the following ways except (A) They involve release of pyrophosphate from each nucleotide added (B) They require activated nucleotide precursor and Mg2+ (C) The direction of synthesis is 5’ → 3’ (D) They require a primer
Description : In the pathway leading to biosynthesis of acetoacetate from acetyl-CoA in liver, the immediate precursor of aceotacetate is (A) Acetoacetyl-CoA (B) 3-Hydroxybutyryl-CoA (C) 3-Hydroxy-3-methyl-glutaryl-CoA (D) 3-Hydroxybutyrate
Description : The first pyrimidine nucleotide to be formed in de novo synthesis pathway is (A) UMP (B) CMP (C) CTP (D) TMP
Description : Galactose 1-phosphate is converted to uridine diphosphate galactose, the reaction is catalysed by the enzyme: (A) Glactokinase (B) Galactose 1-phosphate uridyl transferase (C) Uridine diphospho galactose 4-epimerase (D) UDP glucose pyrophosphorylase
Description : UDP glucose is converted to UDP glucurronate, a reaction catalysed by UDP glucose dehydrogenase requires (A) NAD+ (B) FAD (C) NADP (D) FMN
Description : Which of the following reaction gives lactose? (A) UDP galactose and glucose (B) UDP glucose and galactose (C) Glucose and Galactose (D) Glucose, Galactose and UTP
Description : Nucleotide found free in the cells is: (a) CAMP (b) AMP (c) ADP (d) ATP
Last Answer : Ans. ((d))
Description : The pumping of Na+ depends on a. ADP b. ATP c. GDP d. All
Last Answer : ATP
Description : Removal of BSP dye by the liver involves conjugation with (A) Thiosulphate (B) Glutamine (C) Cystein component of glutathione (D) UDP glucuronate
Description : Which one of the following would be expected in pyruvate kinase deficiency? (A) Increased levels of lactate in the R.B.C (B) Hemolytic anemia (C) Decreased ratio of ADP to ATP in R.B.C (D) Increased phosphorylation of Glucose to Glucose-6-phosphate
Description : A substance that is not an intermediate in the formation of D-glucuronic acid from glucose is (A) Glucoss-1-p (B) 6-Phosphogluconate (C) Glucose-6-p (D) UDP-Glucose
Description : UDP-Glucose is converted to UDPGlucuronic acid by (A) ATP (B) GTP (C) NADP+ (D) NAD+
Description : For glycogenesis, Glucose should be converted to (A) Glucuronic acid (B) Pyruvic acid (C) UDP glucose (D) Sorbitol
Description : Which of the following depicts the correct pathway of transport of sperms? (a) Rete testis → Efferent ductules → Epididymis → Vas deferens (b) Rete testis → Epididymis → Efferent ductules → Vas ... → Efferent ductules → Epididymis (d) Efferent ductules → Rete testis → Vas deferens → Epididymis
Last Answer : (a) Rete testis → Efferent ductules → Epididymis → Vas deferens
Description : The cardiac muscarinic receptors: A. Are of the M1 subtype B. Are of the M2 subtype C. Are selectively blocked by pirenzepine D. Function through the PIP2 → IP3/DAG pathway
Last Answer : B. Are of the M2 subtype
Description : Translocation of the newly formed peptidyl tRNA at the A site into the empty P site involves (A) EF-II, GTP (B) EF-I, GTP (C) EF-I, GDP (D) Peptidyl transferase, GTP
Description : An essential agent for converting glucose to glycogen in liver is (A) Latic acid (B) GTP (C) UTP (D) Pyruvic acid
Description : Glucose-1-phosphate liberated from glycogen cannot be converted into free glucose in (A) Liver (B) Kidneys (C) Muscles (D) Brain
Description : Glycogen phosphorylase liberates the following from glycogen (A) Glucose (B) Glucose-6-phosphate (C) Glucose-1-phosphate (D) Maltose
Description : Pompe ’s d isease is caused due to deficiency of (A) Lysosomal α-1→4 and 1→6-glucosidase (B) Glucose-6-phosphatase (C) Glycogen synthase (D) Phosphofructokinase
Description : Action of glycogen synthase is inhibited by (A) Insulin (B) Glucose (C) Mg2+ (D) Cyclic AMP
Description : Allosteric activator of glycogen synthase is (A) Glucose (B) Glucose-6-Phosphate (C) UTP (D) Glucose-1-phosphate
Description : The process of breakdown of glycogen to glucose in the liver and pyruvate and lacate in the muscle is known as (A) Glyogenesis (B) Glycogenolysis (C) Gluconeogenesis (D) Cellular degradation
Description : Renal glycosuria occurs due to (A) Increased filtration of glucose in glomeruli (B) Increased secretion of glucose by renal tubular cells (C) Decreased reabsorption of glucose by renal tubular cells (D) Increased conversion of glycogen into glucose in tubular cells
Description : The carbohydrate reserved in human body is (A) Starch (B) Glucose (C) Glycogen (D) Inulin
Description : Starch and glycogen are polymers of (A) Fructose (B) Mannose (C) α−D-Glucose (D) Galactose
Description : An essential for converting Glucose to Glycogen in Liver is (A) Lactic acid (B) GTP (C) CTP (D) UTP CARBOHYDRATES AND CARBOHYDRATE METABOLISM 19
Last Answer : D