The first enzyme found to have isoenzymes was (A) Alkaline Phosphatase (B) Lactate dehydrogenase (C) Acid Phosphatase (D) Creatine kinase

The first enzyme found to have isoenzymes was (A) Alkaline Phosphatase (B) Lactate dehydrogenase (C) Acid Phosphatase (D) Creatine kinase
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The “Primaquin sensitivity types of haemolytic anaemia has been found to relate to reduced R.B.C activity of which enzyme? (A) Pyruvate kinase deficiency (B) Glucose-6-phosphatase deficiency (C) Glucose-6-p dehydrogenase deficiency (D) Hexokinase deficiency

Description : The “Primaquin sensitivity types of haemolytic anaemia has been found to relate to reduced R.B.C activity of which enzyme? (A) Pyruvate kinase deficiency (B) Glucose-6-phosphatase deficiency (C) Glucose-6-p dehydrogenase deficiency (D) Hexokinase deficiency

Last Answer : C

Isoenzymes of lactate dehydrogenase are useful for the diagnosis of (A) Heart disease (B) Kidney disease (C) Liver disease (D) Both (A) and (C)

Description : Isoenzymes of lactate dehydrogenase are useful for the diagnosis of (A) Heart disease (B) Kidney disease (C) Liver disease (D) Both (A) and (C)

Last Answer : Answer : D

The liver enzyme which is sensitive indicator of liver cell injury and is most helpful in recognizing acute hepatocellular diseases is Options: 1) Alkaline Phosphatase 2) Aspartate aminotransferase 3) Gamma glutamyl Transpeptidase 4) Creatine Phosphokinase

Description : The liver enzyme which is sensitive indicator of liver cell injury and is most helpful in recognizing acute hepatocellular diseases is Options: 1) Alkaline Phosphatase 2) Aspartate aminotransferase 3) Gamma glutamyl Transpeptidase 4) Creatine Phosphokinase

Last Answer : Correct Answer: 2) Aspartate aminotransferase

Schardinger’s enzyme is (A) Lactate dehydrogenase (B) Xanthine dehydrogenase (C) Uric oxidase (D) L amino acid dehydrogenase

Description : Schardinger’s enzyme is (A) Lactate dehydrogenase (B) Xanthine dehydrogenase (C) Uric oxidase (D) L amino acid dehydrogenase

Last Answer : Answer : B

From the following myocardial infarction, the earliest serum enzyme to rise is (A) Creatine Kinase (B) GOT (C) GPT (D) LDH

Description : From the following myocardial infarction, the earliest serum enzyme to rise is (A) Creatine Kinase (B) GOT (C) GPT (D) LDH

Last Answer : Answer : A

Which of the following serum enzyme rises in myocardial infarction: (A) Creatine kinase (B) GOT (C) LDH (D) All of these

Description : Which of the following serum enzyme rises in myocardial infarction: (A) Creatine kinase (B) GOT (C) LDH (D) All of these

Last Answer : Answer : D

Which of the following is known as bone forming enzyme? (A) Alkaline phosphatase (B) Acid phosphatase (C) Leucine aminopeptidase (D) γ-glutamyl transpeptidase

Description : Which of the following is known as bone forming enzyme? (A) Alkaline phosphatase (B) Acid phosphatase (C) Leucine aminopeptidase (D) γ-glutamyl transpeptidase

Last Answer : Answer : A

The following is an enzyme required for glycolysis: (A) Pyruvate kinase (B) Pyruvate carboxylase (C) Glucose-6-phosphatase (D) Glycerokinase

Description : The following is an enzyme required for glycolysis: (A) Pyruvate kinase (B) Pyruvate carboxylase (C) Glucose-6-phosphatase (D) Glycerokinase

Last Answer : A

In sugarcane plant 14CO2 is fixed to malic acid, in which the enzyme that fixes CO2 is (a) ribulose biphosphate carboxylase (b) phosphoenol pyruvic acid carboxylase (c) ribulose phosphate kinase (d) fructose phosphatase.

Description : In sugarcane plant 14CO2 is fixed to malic acid, in which the enzyme that fixes CO2 is (a) ribulose biphosphate carboxylase (b) phosphoenol pyruvic acid carboxylase (c) ribulose phosphate kinase (d) fructose phosphatase.

Last Answer : (b) phosphoenol pyruvic acid carboxylase

Zn is present as prosthetic group in this enzyme: (A) Carbonic anhydrase (B) Carboxy peptidase (C) Lactate dehydrogenase (D) All of these

Description : Zn is present as prosthetic group in this enzyme: (A) Carbonic anhydrase (B) Carboxy peptidase (C) Lactate dehydrogenase (D) All of these

Last Answer : Answer : D

Which of the following is an allosteric enzyme? (A) Phosphohexose isomerase (B) Phosphotriose isomerase (C) Lactate dehydrogenase (D) Phosphofructokinase

Description : Which of the following is an allosteric enzyme? (A) Phosphohexose isomerase (B) Phosphotriose isomerase (C) Lactate dehydrogenase (D) Phosphofructokinase

Last Answer : Answer : D

An example of functional plasma enzyme is (A) Lipoprotein lipase (B) Amylase (C) Aminotransferase (D) Lactate dehydrogenase

Description : An example of functional plasma enzyme is (A) Lipoprotein lipase (B) Amylase (C) Aminotransferase (D) Lactate dehydrogenase

Last Answer : Answer : A

An enzyme catalyzing oxidoreduction, using oxygen as hydrogen acceptor is (A) Cytochrome oxidase (B) Lactate dehydrogenase (C) Malate dehydrogenase (D) Succinate dehydrogenase

Description : An enzyme catalyzing oxidoreduction, using oxygen as hydrogen acceptor is (A) Cytochrome oxidase (B) Lactate dehydrogenase (C) Malate dehydrogenase (D) Succinate dehydrogenase

Last Answer : Answer : A

Example of an extracellular enzyme is (A) Lactate dehydrogenase (B) Cytochrome oxidase (C) Pancreatic lipase (D) Hexokinase

Description : Example of an extracellular enzyme is (A) Lactate dehydrogenase (B) Cytochrome oxidase (C) Pancreatic lipase (D) Hexokinase

Last Answer : Answer : C

The following enzyme is required for the hexose monophosphate shunt pathway: (A) Glucose-6-phosphatase (B) Phosphorylase (C) Aldolase (D) Glucose-6-phosphate dehydrogenase

Description : The following enzyme is required for the hexose monophosphate shunt pathway: (A) Glucose-6-phosphatase (B) Phosphorylase (C) Aldolase (D) Glucose-6-phosphate dehydrogenase

Last Answer : D

An enzyme of pyrimidine nucleotides biosynthesis regulated at the genetic level by apparently coordinate repression and derepression is (A) Carbamoyl phosphate synthetase (B) Dihydroorotate dehydrogenase (C) Thymidine kinase (D) Deoxycytidine kinase

Description : An enzyme of pyrimidine nucleotides biosynthesis regulated at the genetic level by apparently coordinate repression and derepression is (A) Carbamoyl phosphate synthetase (B) Dihydroorotate dehydrogenase (C) Thymidine kinase (D) Deoxycytidine kinase

Last Answer : Answer : A

Insulin has no effect on the activity of the enzyme: (A) Glycogen synthetase (B) Fructokinase (C) Pyruvate kinase (D) Pyruvate dehydrogenase

Description : Insulin has no effect on the activity of the enzyme: (A) Glycogen synthetase (B) Fructokinase (C) Pyruvate kinase (D) Pyruvate dehydrogenase

Last Answer : Answer : B

Dietary deficiency of thiamin inhibits the activity of the enzyme: (A) Pyruvate kinase (B) Pyruvate dehydrogenase (C) Phosphofructokinase (D) Enolase

Description : Dietary deficiency of thiamin inhibits the activity of the enzyme: (A) Pyruvate kinase (B) Pyruvate dehydrogenase (C) Phosphofructokinase (D) Enolase

Last Answer : Answer : B

In glycolytic pathway, iodacetate inhibits the activity of the enzyme: (A) Phosphotriose isomerase (B) Glyceraldehyde-3-phosphate dehydrogenase (C) Pyruvate kinase (D) Phosphofructokinase

Description : In glycolytic pathway, iodacetate inhibits the activity of the enzyme: (A) Phosphotriose isomerase (B) Glyceraldehyde-3-phosphate dehydrogenase (C) Pyruvate kinase (D) Phosphofructokinase

Last Answer : Answer : B

All the following statements about obstructive jaundice are true except (A) Prothrombin time may be prolonged due to impaired absorption of vitamin K (B) Serum alkaline phosphatase may be raised due to increased release of the enzyme from liver cells (C) Bile salts may enter systemic circulation due to biliary obstruction (D) There is no defect in conjugation of bilirubin

Description : All the following statements about obstructive jaundice are true except (A) Prothrombin time may be prolonged due to impaired absorption of vitamin K (B) Serum alkaline phosphatase may be raised ... systemic circulation due to biliary obstruction (D) There is no defect in conjugation of bilirubin

Last Answer : Answer : B

In conversion of lactic acid to glucose, three reactions of glycolytic pathway are circumvented, which of the following enzymes do not participate? (A) Pyruvate carboxylase (B) Phosphoenol pyruvate carboxy kinase (C) Pyruvate kinase (D) Glucose-6-phosphatase

Description : In conversion of lactic acid to glucose, three reactions of glycolytic pathway are circumvented, which of the following enzymes do not participate? (A) Pyruvate carboxylase (B) Phosphoenol pyruvate carboxy kinase (C) Pyruvate kinase (D) Glucose-6-phosphatase

Last Answer : Answer : B

In conversion of Lactic acid to Glucose, three reactions of Glycolytic pathway are circumvented, which of the following enzymes do not participate? (A) Pyruvate Carboxylase (B) Phosphoenol pyruvate carboxy kinase (C) Pyruvate kinase (D) Glucose-6-phosphatase

Description : In conversion of Lactic acid to Glucose, three reactions of Glycolytic pathway are circumvented, which of the following enzymes do not participate? (A) Pyruvate Carboxylase (B) Phosphoenol pyruvate carboxy kinase (C) Pyruvate kinase (D) Glucose-6-phosphatase

Last Answer : C

All enzymes of TCA cycle are located in the mitochondrial matrix except one which is located in inner mitochondrial membranes in eukaryotes and in cytosol in prokaryotes. This enzyme is (a) isocitrate dehydrogenase (b) malate dehydrogenase (c) succinate dehydrogenase (d) lactate dehydrogenase.

Description : All enzymes of TCA cycle are located in the mitochondrial matrix except one which is located in inner mitochondrial membranes in eukaryotes and in cytosol in prokaryotes. This enzyme is (a) isocitrate dehydrogenase (b) malate dehydrogenase (c) succinate dehydrogenase (d) lactate dehydrogenase.

Last Answer : (c) succinate dehydrogenase

Ethanol decreases gluconeogenesis by (A) Inhibiting glucose-6-phosphatase (B) Inhibiting PEP carboxykinase (C) Converting NAD+ into NADH and decreasing the availability of pyruvate (D) Converting NAD+ into NADH and decreasing the availability of lactate

Description : Ethanol decreases gluconeogenesis by (A) Inhibiting glucose-6-phosphatase (B) Inhibiting PEP carboxykinase (C) Converting NAD+ into NADH and decreasing the availability of pyruvate (D) Converting NAD+ into NADH and decreasing the availability of lactate

Last Answer : C

Creatine kinase is present in all of the following except (A) Liver (B) Myocardium (C) Muscles (D) Brain

Description : Creatine kinase is present in all of the following except (A) Liver (B) Myocardium (C) Muscles (D) Brain

Last Answer : Answer : A

Creatine kinase (CK) level in serum is increased in which conditions?

Description : Creatine kinase (CK) level in serum is increased in which conditions? 

Last Answer : Myocardial infarction, muscular dystrophies.

Which one of the following statements concerning glucose metabolism is correct? (A) The conversion of Glucose to lactate occurs only in the R.B.C (B) Glucose enters most cells by a mechanism in which Na+ and glucose are co-transported (C) Pyruvate kinase catalyses an irreversible reaction (D) An elevated level of insulin leads to a decreased level of fructose 2, 6-bisphosphate in hepatocyte

Description : Which one of the following statements concerning glucose metabolism is correct? (A) The conversion of Glucose to lactate occurs only in the R.B.C (B) Glucose enters most cells by a mechanism in ... ) An elevated level of insulin leads to a decreased level of fructose 2, 6-bisphosphate in hepatocyte

Last Answer : C

Which one of the following would be expected in pyruvate kinase deficiency? (A) Increased levels of lactate in the R.B.C (B) Hemolytic anemia (C) Decreased ratio of ADP to ATP in R.B.C (D) Increased phosphorylation of Glucose to Glucose-6-phosphate

Description : Which one of the following would be expected in pyruvate kinase deficiency? (A) Increased levels of lactate in the R.B.C (B) Hemolytic anemia (C) Decreased ratio of ADP to ATP in R.B.C (D) Increased phosphorylation of Glucose to Glucose-6-phosphate

Last Answer : B

This catalyzes formation of CoA derivatives from fatty acid, CoA and ATP: (A) Acyl CoA dehydrogenase (B) Enoyl hydrase (C) β-OH acyl CoA dehydrogenase (D) Thio kinase

Description : This catalyzes formation of CoA derivatives from fatty acid, CoA and ATP: (A) Acyl CoA dehydrogenase (B) Enoyl hydrase (C) β-OH acyl CoA dehydrogenase (D) Thio kinase

Last Answer : Answer : D

Zinc is a cofactor for (A) Acid phosphatase (B) Alkaline phosphatase (C) Amylase (D) Lipase

Description : Zinc is a cofactor for (A) Acid phosphatase (B) Alkaline phosphatase (C) Amylase (D) Lipase

Last Answer : Answer : B

All of the following are zinc-containing enzymes except (A) Acid Phosphatase (B) Alkaline Phosphatase (C) Carbonic anhydrase (D) RNA polymerase

Description : All of the following are zinc-containing enzymes except (A) Acid Phosphatase (B) Alkaline Phosphatase (C) Carbonic anhydrase (D) RNA polymerase

Last Answer : Answer : A

cAMD is destroyed by (A) Adenylate cyclase (B) Phosphodiesterase (C) Synthetase phosphatase (D) Synthetase kinase

Description : cAMD is destroyed by (A) Adenylate cyclase (B) Phosphodiesterase (C) Synthetase phosphatase (D) Synthetase kinase

Last Answer : Answer : B

Glucose-6-phosphatase and PEP carboxy kinase are regulated by (A) Covalent modification (B) Allosteric regulation (C) Induction and repression (D) All of these

Description : Glucose-6-phosphatase and PEP carboxy kinase are regulated by (A) Covalent modification (B) Allosteric regulation (C) Induction and repression (D) All of these

Last Answer : Answer : C

Different isoenzymes of an enzyme have the same (A) Amino acid sequence (B) Michaelis constant (C) Catalytic activity (D) All of these

Description : Different isoenzymes of an enzyme have the same (A) Amino acid sequence (B) Michaelis constant (C) Catalytic activity (D) All of these

Last Answer : Answer : C

Which of the following is not having an apoenzyme and coenzyme? (A) Lactate dehydrogenase (B) Succinate dehydrogenase (C) Malate dehydrogenase (D) Pepsin

Description : Which of the following is not having an apoenzyme and coenzyme? (A) Lactate dehydrogenase (B) Succinate dehydrogenase (C) Malate dehydrogenase (D) Pepsin

Last Answer : Answer : D

Coenzymes derived from the vitamin shown below are required by which of the following enzymes? (A) Lactate dehydrogenase (B) Glutamate dehydrogenase (C) Pyruvate dehydrogenase (D) Malate dehydrogenase

Description : Coenzymes derived from the vitamin shown below are required by which of the following enzymes? (A) Lactate dehydrogenase (B) Glutamate dehydrogenase (C) Pyruvate dehydrogenase (D) Malate dehydrogenase

Last Answer : Answer : C

Lactate dehydrogenase is a (A) Monomer (B) Dimer (C) Tetramer (D) Hexamer

Description : Lactate dehydrogenase is a (A) Monomer (B) Dimer (C) Tetramer (D) Hexamer

Last Answer : Answer : C

Lactate dehydrogenase is located in (A) Lysosomes (B) Mitochondria (C) Cytosol (D) Microsomes

Description : Lactate dehydrogenase is located in (A) Lysosomes (B) Mitochondria (C) Cytosol (D) Microsomes

Last Answer : Answer : C

Which of the following isoenzyme of lactate dehydrogenase is raised in serum in myocardial infarction: (A) LD1 (B) LD2 (C) LD1 and LD2 (D) LD5

Description : Which of the following isoenzyme of lactate dehydrogenase is raised in serum in myocardial infarction: (A) LD1 (B) LD2 (C) LD1 and LD2 (D) LD5

Last Answer : Answer : C

Serum lactate dehydrogenase rises in (A) Viral hepatitis (B) Myocardial infarction (C) Carcinomatosis (D) All of these

Description : Serum lactate dehydrogenase rises in (A) Viral hepatitis (B) Myocardial infarction (C) Carcinomatosis (D) All of these

Last Answer : Answer : D

Pyruvate dehydrogenase a multienzyme complex is required for the production of (A) Acetyl-CoA (B) Lactate (C) Phosphoenolpyruvate (D) Enolpyruvate

Description : Pyruvate dehydrogenase a multienzyme complex is required for the production of (A) Acetyl-CoA (B) Lactate (C) Phosphoenolpyruvate (D) Enolpyruvate

Last Answer : Answer : A

Lactate dehydrogenase has how many iso-enzymes?

Description : Lactate dehydrogenase has how many iso-enzymes?

Last Answer : H4, H3M, H2M2, M3H and M4 varieties, forming five iso-enzymes. All these five forms are seen in all persons.

Lactate dehydrogenase has how many polypeptide subunits?

Description : Lactate dehydrogenase has how many polypeptide subunits? 

Last Answer : Four. It is a tetramer.

Which one of the following enzymes requires a coenzyme derived from the vitamin whose structure is shown below? (A) Enoyl CoA hydratase (B) Phosphofructokinase (C) Glucose-6-phosphatase (D) Glucose-6-phosphate dehydrogenase

Description : Which one of the following enzymes requires a coenzyme derived from the vitamin whose structure is shown below? (A) Enoyl CoA hydratase (B) Phosphofructokinase (C) Glucose-6-phosphatase (D) Glucose-6-phosphate dehydrogenase

Last Answer : Answer : D

Copper is associated with _____ mitochondria' enzymes. (1) Cytochrome oxidase (2) Succinic dehydrogenase (3) Catalase (4) Acid phosphatase

Description : Copper is associated with _____ mitochondria' enzymes. (1) Cytochrome oxidase (2) Succinic dehydrogenase (3) Catalase (4) Acid phosphatase

Last Answer : (1) Cytochrome oxidase Explanation: Copper is involved in normalized function of many enzymes, such as cytochrome oxidase, which is complex IV in mitochondrial electron ... transportation, antioxidant and free radical scavenging and neutralization, and neurotransmitter synthesis, respectively.

Copper is associated with ____ mitochondrial enzymes. (1) Cytochrome oxidase (2) Succinic dehydrogenase (3) Catalase (4) Acid phosphatase

Description : Copper is associated with ____ mitochondrial enzymes. (1) Cytochrome oxidase (2) Succinic dehydrogenase (3) Catalase (4) Acid phosphatase

Last Answer : Cytochrome oxidase

An 11 year old girl presents with the following complaints (1) Difficulty in climbing upstairs and combing her hair (2) Maculopapular rash over MCP joints (3) Gower's sign Positive. The most appropriate investigation to be advised is Options: 1) ESR 2) Creatine Kinase 3) RA Factor 4) ANA antibodies test

Description : An 11 year old girl presents with the following complaints (1) Difficulty in climbing upstairs and combing her hair (2) Maculopapular rash over MCP joints (3) Gower's sign Positive. The most appropriate ... advised is Options: 1) ESR 2) Creatine Kinase 3) RA Factor 4) ANA antibodies test

Last Answer : Correct Answer: 2) Creatine Kinase

Which of the following enzymes incorporates inorganic phosphate into the substrate? (A) Phosphoglycerate kinase (B) Glyceraldehyde-3-phosphate dehydrogenase (C) Pyruvate kinase (D) Enolase

Description : Which of the following enzymes incorporates inorganic phosphate into the substrate? (A) Phosphoglycerate kinase (B) Glyceraldehyde-3-phosphate dehydrogenase (C) Pyruvate kinase (D) Enolase

Last Answer : Answer : A

Enzymes leading to the high energy phosphorylation of substrates during glycolysis include which of the following? (A) Phosphoglycerate kinase (B) Enolase (C) Pyruvate Kinase (D) Glyceraldehyde-3-phosphate dehydrogenase

Description : Enzymes leading to the high energy phosphorylation of substrates during glycolysis include which of the following? (A) Phosphoglycerate kinase (B) Enolase (C) Pyruvate Kinase (D) Glyceraldehyde-3-phosphate dehydrogenase

Last Answer : Answer : D