Which of the following is known as bone forming enzyme? (A) Alkaline phosphatase (B) Acid phosphatase (C) Leucine aminopeptidase (D) γ-glutamyl transpeptidase

Which of the following is known as bone forming enzyme? (A) Alkaline phosphatase (B) Acid phosphatase (C) Leucine aminopeptidase (D) γ-glutamyl transpeptidase
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The liver enzyme which is sensitive indicator of liver cell injury and is most helpful in recognizing acute hepatocellular diseases is Options: 1) Alkaline Phosphatase 2) Aspartate aminotransferase 3) Gamma glutamyl Transpeptidase 4) Creatine Phosphokinase

Description : The liver enzyme which is sensitive indicator of liver cell injury and is most helpful in recognizing acute hepatocellular diseases is Options: 1) Alkaline Phosphatase 2) Aspartate aminotransferase 3) Gamma glutamyl Transpeptidase 4) Creatine Phosphokinase

Last Answer : Correct Answer: 2) Aspartate aminotransferase

Serum gamma glutamyl transpeptidase is raised in (A) Haemolytic jaundice (B) Myocardial infarction (C) Alcoholic hepatitis (D) Acute cholecystitis

Description : Serum gamma glutamyl transpeptidase is raised in (A) Haemolytic jaundice (B) Myocardial infarction (C) Alcoholic hepatitis (D) Acute cholecystitis

Last Answer : Answer : C

Which of the following enzyme typically elevated in alcoholism? (A) Serum ALP (B) Serum GOT (C) Serum γ-GT (D) Serum acid phosphatase

Description : Which of the following enzyme typically elevated in alcoholism? (A) Serum ALP (B) Serum GOT (C) Serum γ-GT (D) Serum acid phosphatase

Last Answer : Answer : C

The α-ketoacid is decarboxylated by H2O2 forming a carboxylic acid with one carbon atom less in the absence of the enzyme: (A) Catalase (B) Decarboxylase (C) Deaminase (D) Phosphatase

Description : The α-ketoacid is decarboxylated by H2O2 forming a carboxylic acid with one carbon atom less in the absence of the enzyme: (A) Catalase (B) Decarboxylase (C) Deaminase (D) Phosphatase

Last Answer : Answer : A

The first enzyme found to have isoenzymes was (A) Alkaline Phosphatase (B) Lactate dehydrogenase (C) Acid Phosphatase (D) Creatine kinase

Description : The first enzyme found to have isoenzymes was (A) Alkaline Phosphatase (B) Lactate dehydrogenase (C) Acid Phosphatase (D) Creatine kinase

Last Answer : Answer : B

Leucine aminopeptidase - blood?

Description : Leucine aminopeptidase - blood?

Last Answer : DefinitionLeucine aminopeptidase is a protein, called an enzyme, that is normally found in liver cells.Serum leucine aminopeptidase is a test that measures how much of this protein is in your blood.Your ... blood collects into an airtight vial or tube attached to the needle. The elastic band is r

All the following statements about obstructive jaundice are true except (A) Prothrombin time may be prolonged due to impaired absorption of vitamin K (B) Serum alkaline phosphatase may be raised due to increased release of the enzyme from liver cells (C) Bile salts may enter systemic circulation due to biliary obstruction (D) There is no defect in conjugation of bilirubin

Description : All the following statements about obstructive jaundice are true except (A) Prothrombin time may be prolonged due to impaired absorption of vitamin K (B) Serum alkaline phosphatase may be raised ... systemic circulation due to biliary obstruction (D) There is no defect in conjugation of bilirubin

Last Answer : Answer : B

Which enzyme estimation will be helpful in differentiating the elevated serum ALP found in obstructive jaundice as well as bone disorders? (A) Serum AST (B) Serum ALT (C) Serum LDH (D) Serum γ-GT

Description : Which enzyme estimation will be helpful in differentiating the elevated serum ALP found in obstructive jaundice as well as bone disorders? (A) Serum AST (B) Serum ALT (C) Serum LDH (D) Serum γ-GT

Last Answer : Answer : D

Zinc is a cofactor for (A) Acid phosphatase (B) Alkaline phosphatase (C) Amylase (D) Lipase

Description : Zinc is a cofactor for (A) Acid phosphatase (B) Alkaline phosphatase (C) Amylase (D) Lipase

Last Answer : Answer : B

All of the following are zinc-containing enzymes except (A) Acid Phosphatase (B) Alkaline Phosphatase (C) Carbonic anhydrase (D) RNA polymerase

Description : All of the following are zinc-containing enzymes except (A) Acid Phosphatase (B) Alkaline Phosphatase (C) Carbonic anhydrase (D) RNA polymerase

Last Answer : Answer : A

Which of the following is a substratespecific enzyme? (A) Hexokinase (B) Thiokinase (C) Lactase (D) Aminopeptidase

Description : Which of the following is a substratespecific enzyme? (A) Hexokinase (B) Thiokinase (C) Lactase (D) Aminopeptidase

Last Answer : Answer : C

PRPP glutamyl amidotransferase, the first enzyme uniquely committed to purine synthesis is feed back inhibited by (A) AMP (B) IMP (C) XMP (D) CMP

Description : PRPP glutamyl amidotransferase, the first enzyme uniquely committed to purine synthesis is feed back inhibited by (A) AMP (B) IMP (C) XMP (D) CMP

Last Answer : Answer : A

An enzyme which acts as allosteric regulator and sensitive to both phosphate concentration and to the purine nucleotides is (A) PRPP synthetase (B) PRPP glutamyl midotransferase (C) HGPR Tase (D) Formyl transferase

Description : An enzyme which acts as allosteric regulator and sensitive to both phosphate concentration and to the purine nucleotides is (A) PRPP synthetase (B) PRPP glutamyl midotransferase (C) HGPR Tase (D) Formyl transferase

Last Answer : Answer : A

Calcitriol facilitates calcium absorption by increasing the synthesis of the following in intestinal mucosa: (A) Calcium Binding Protein (B) Alkaline Phosphatase (C) Calcium-dependent ATPase (D) All of these

Description : Calcitriol facilitates calcium absorption by increasing the synthesis of the following in intestinal mucosa: (A) Calcium Binding Protein (B) Alkaline Phosphatase (C) Calcium-dependent ATPase (D) All of these

Last Answer : Answer : D

Serum alkaline phosphatase is greatly increased in (A) Haemolytic jaundice (B) Hepatic jaundice (C) Obstructive jaundice (D) None of these

Description : Serum alkaline phosphatase is greatly increased in (A) Haemolytic jaundice (B) Hepatic jaundice (C) Obstructive jaundice (D) None of these

Last Answer : Answer : C

An inherited or acquired renal tubular defect in the reabsorption of phosphate (Vit D resistant ricket) is characterized with (A) Normal serum Phosphate (B) High serum phosphate (C) A low blood phosphorous with elevated alkaline Phosphate (D) A high blood phosphorous with decreased alkaline phosphatase

Description : An inherited or acquired renal tubular defect in the reabsorption of phosphate (Vit D resistant ricket) is characterized with (A) Normal serum Phosphate (B) High serum phosphate (C ... blood phosphorous with elevated alkaline Phosphate (D) A high blood phosphorous with decreased alkaline phosphatase

Last Answer : Answer : C

Alkaline phosphatase is present in (A) Liver (B) Bones (C) Intestinal mucosa (D) All of these

Description : Alkaline phosphatase is present in (A) Liver (B) Bones (C) Intestinal mucosa (D) All of these

Last Answer : Answer : D

Alkaline phosphatase is present in (A) Liver (B) Bones (C) Placenta (D) All of these

Description : Alkaline phosphatase is present in (A) Liver (B) Bones (C) Placenta (D) All of these

Last Answer : Answer : D

The normal serum alkaline phosphatase activity ranges from (A) 1.0–5.0 KA units/100 ml (B) 5.0–13.0 KA units/100 ml (C) 0.8–2.3 KA units/100 ml (D) 13.0–21.0 KA units/100 ml

Description : The normal serum alkaline phosphatase activity ranges from (A) 1.0–5.0 KA units/100 ml (B) 5.0–13.0 KA units/100 ml (C) 0.8–2.3 KA units/100 ml (D) 13.0–21.0 KA units/100 ml

Last Answer : Answer : B

All the following statements about obstructive jaundice are true except (A) Conjugated bilirubin in serum is normal (B) Total bilirubin in serum is raised (C) Bile salts are present in urine (D) Serum alkaline phosphatase is raised

Description : All the following statements about obstructive jaundice are true except (A) Conjugated bilirubin in serum is normal (B) Total bilirubin in serum is raised (C) Bile salts are present in urine (D) Serum alkaline phosphatase is raised

Last Answer : Answer : A

Hepatocellular jaundice as compared to pure obstructive type of jaundice is characterized by (A) Increased serum alkaline phosphate, LDH and ALT (B) Decreased serum alkaline phosphatase, LDH and ALT (C) Increased serum alkaline phosphatase and decreased levels of LDH and ALT (D) Decreased serum alkaline phosphatase and increased serum LDH and ALT

Description : Hepatocellular jaundice as compared to pure obstructive type of jaundice is characterized by (A) Increased serum alkaline phosphate, LDH and ALT (B) Decreased serum alkaline phosphatase, LDH and ALT (C ... levels of LDH and ALT (D) Decreased serum alkaline phosphatase and increased serum LDH and ALT

Last Answer : Answer : D

A jaundice in which serum alanine transaminase and alkaline phosphatase are normal is (A) Hepatic jaundice (B) Hemolytic jaundice (C) Parenchymatous jaundice (D) Obstructive Jaundice

Description : A jaundice in which serum alanine transaminase and alkaline phosphatase are normal is (A) Hepatic jaundice (B) Hemolytic jaundice (C) Parenchymatous jaundice (D) Obstructive Jaundice

Last Answer : Answer : B

A 19 year-old female is referred following a visit to the dentist where marked erosion of her teeth was noted. She was entirely asymptomatic and her only medication was the oral contraceptive pill. On examination her blood pressure was 110/70 mmHg and her body mass index was 21.5 kg/m2 (18 - 25). Investigations sodium 135 mmol/l potassium 2.1 mmol/l bicarbonate 42 mmol/l urea 2.6 mol/L corrected calcium 2.08 mmol/ alkaline phosphatase 201 iu/l (50-110) What is the most likely diagnosis? 1) Bulimia nervosa 2) Conn's syndrome 3) Laxative abuse 4) Pregnancy 5) Primary hypoparathyroidism

Description : A 19 year-old female is referred following a visit to the dentist where marked erosion of her teeth was noted. She was entirely asymptomatic and her only medication was the oral contraceptive pill ... ) Bulimia nervosa 2) Conn's syndrome 3) Laxative abuse 4) Pregnancy 5) Primary hypoparathyroidism

Last Answer : Answers-5 This patient has tooth erosion associated with hypokalaemic metabolic alkalosis and hypocalcaemia. This suggests a diagnosis of hypoparathyroidism. Conn's is unlikely in this age group, is ... raised alkaline phosphatase would not be expected. Early pregnancy would not fit this picture.

Serum biochemistry of a 60 year old man revealed calcium of 1.98 mmol/l and phosphate of 0.55 mmol/l with an alkaline phosphatase of 450 IU/l.Which among the following mosts suits with the above serum biochemistry? 1) Osteoporosis 2) Osteomalacia 3) Pagets Disease 4) Secondary Hyperparathyroidism 5) Renal failure

Description : Serum biochemistry of a 60 year old man revealed calcium of 1.98 mmol/l and phosphate of 0.55 mmol/l with an alkaline phosphatase of 450 IU/l.Which among the following mosts suits ... biochemistry? 1) Osteoporosis 2) Osteomalacia 3) Pagets Disease 4) Secondary Hyperparathyroidism 5) Renal failure

Last Answer : Answers-2 Osteomalacia is associated with low calcium and phosphate with raised alkaline phosphatase. Serum biochemistry is normal in osteoporosis. Pagets disease is associated with normal ... renal failure when tertiary hyperparathyroidism sets in there is low calcium with raised phosphate.

It is said that nucleotide phosphatase (NTP) is a better index of obstructive liver disease than alkaline phosphatase (ALP), why?

Description : It is said that nucleotide phosphatase (NTP) is a better index of obstructive liver disease than alkaline phosphatase (ALP), why?

Last Answer : ALP level is increased in both liver and bone diseases, but NTP is only in liver diseases. 

For alkaline phosphatase, how many iso-enzymes are present?

Description : For alkaline phosphatase, how many iso-enzymes are present?

Last Answer : Six.

Alkaline phosphatase level in serum is elevated in which conditions?

Description : Alkaline phosphatase level in serum is elevated in which conditions?

Last Answer : Moderate increase is seen in hepatic diseases (infective hepatitis, alcoholic hepatitis). High levels may be noticed in obstructive jaundice or cholestasis. Very high levels are seen in bone diseases such as Pagetís disease, rickets, osteomalacia, osteoblastoma, metastatic carcinoma of bone.

Amylopectinosis is caused due to absence of (A) Debranching enzyme (B) Branching enzyme (C) Acid maltase (D) Glucose-6-phosphatase

Description : Amylopectinosis is caused due to absence of (A) Debranching enzyme (B) Branching enzyme (C) Acid maltase (D) Glucose-6-phosphatase

Last Answer : Answer : B

Under physiological conditions the rate limiting enzyme in the generation of angiotensin II is: A. Renin B. Angiotensin converting enzyme C. Aminopeptidase D. Angiotensinase

Description : Under physiological conditions the rate limiting enzyme in the generation of angiotensin II is: A. Renin B. Angiotensin converting enzyme C. Aminopeptidase D. Angiotensinase

Last Answer : A. Renin

Cobalt may act as cofactor for the enzyme: (A) Glycl-glycine dipeptidase (B) Elastase (C) Polynucleotidases (D) Phosphatase

Description : Cobalt may act as cofactor for the enzyme: (A) Glycl-glycine dipeptidase (B) Elastase (C) Polynucleotidases (D) Phosphatase

Last Answer : Answer : A

The enzyme that converts glucose to glucose-6-phosphate is (A) Phosphatase (B) Hexokinase (C) Phosphorylase (D) Glucose synthetase

Description : The enzyme that converts glucose to glucose-6-phosphate is (A) Phosphatase (B) Hexokinase (C) Phosphorylase (D) Glucose synthetase

Last Answer : Answer : B

The enzyme glucose 6-phosphatase is present in (A) Liver (B) Muscle (C) Adipose tissue (D) Brain

Description : The enzyme glucose 6-phosphatase is present in (A) Liver (B) Muscle (C) Adipose tissue (D) Brain

Last Answer : Answer : A

The enzyme glucose-6-phosphatase which catalyses the conversion of glucose 6-phosphate to glucose is not found in (A) Liver (B) Muscle (C) Intestine (D) Kidney

Description : The enzyme glucose-6-phosphatase which catalyses the conversion of glucose 6-phosphate to glucose is not found in (A) Liver (B) Muscle (C) Intestine (D) Kidney

Last Answer : Answer : B

The “Primaquin sensitivity types of haemolytic anaemia has been found to relate to reduced R.B.C activity of which enzyme? (A) Pyruvate kinase deficiency (B) Glucose-6-phosphatase deficiency (C) Glucose-6-p dehydrogenase deficiency (D) Hexokinase deficiency

Description : The “Primaquin sensitivity types of haemolytic anaemia has been found to relate to reduced R.B.C activity of which enzyme? (A) Pyruvate kinase deficiency (B) Glucose-6-phosphatase deficiency (C) Glucose-6-p dehydrogenase deficiency (D) Hexokinase deficiency

Last Answer : C

Glycogen is converted to glucose-1- phosphate by (A) UDPG transferase (B) Branching enzyme (C) Phosphorylase (D) Phosphatase

Description : Glycogen is converted to glucose-1- phosphate by (A) UDPG transferase (B) Branching enzyme (C) Phosphorylase (D) Phosphatase

Last Answer : C

The following enzyme is required for the hexose monophosphate shunt pathway: (A) Glucose-6-phosphatase (B) Phosphorylase (C) Aldolase (D) Glucose-6-phosphate dehydrogenase

Description : The following enzyme is required for the hexose monophosphate shunt pathway: (A) Glucose-6-phosphatase (B) Phosphorylase (C) Aldolase (D) Glucose-6-phosphate dehydrogenase

Last Answer : D

The following is an enzyme required for glycolysis: (A) Pyruvate kinase (B) Pyruvate carboxylase (C) Glucose-6-phosphatase (D) Glycerokinase

Description : The following is an enzyme required for glycolysis: (A) Pyruvate kinase (B) Pyruvate carboxylase (C) Glucose-6-phosphatase (D) Glycerokinase

Last Answer : A

Has anyone had a low alkaline phosphatase reading before on a liver blood test?

Description : Has anyone had a low alkaline phosphatase reading before on a liver blood test?

Last Answer : No worries

ELISA is used to detect viruses where the key reagent is (a) alkaline phosphatase (b) catalase (c) DNA probe (d) RNase.

Description : ELISA is used to detect viruses where the key reagent is (a) alkaline phosphatase (b) catalase (c) DNA probe (d) RNase.

Last Answer : (a) alkaline phosphatase

In sugarcane plant 14CO2 is fixed to malic acid, in which the enzyme that fixes CO2 is (a) ribulose biphosphate carboxylase (b) phosphoenol pyruvic acid carboxylase (c) ribulose phosphate kinase (d) fructose phosphatase.

Description : In sugarcane plant 14CO2 is fixed to malic acid, in which the enzyme that fixes CO2 is (a) ribulose biphosphate carboxylase (b) phosphoenol pyruvic acid carboxylase (c) ribulose phosphate kinase (d) fructose phosphatase.

Last Answer : (b) phosphoenol pyruvic acid carboxylase

From the pentapeptide, phe-ala-leu-lysarg, phenylalanine residue is split off by (A) Trypsin (B) Chymotrypsin (C) Aminopeptidase (D) Carboxypeptidase

Description : From the pentapeptide, phe-ala-leu-lysarg, phenylalanine residue is split off by (A) Trypsin (B) Chymotrypsin (C) Aminopeptidase (D) Carboxypeptidase

Last Answer : Answer : C

Whcih of the following is a proenzyme? (A) Carboxypeptidase (B) Aminopeptidase (C) Chymotrypsin (D) Pepsinogen ENZYMES 159

Description : Whcih of the following is a proenzyme? (A) Carboxypeptidase (B) Aminopeptidase (C) Chymotrypsin (D) Pepsinogen ENZYMES 159

Last Answer : Answer : D

Pancreatic juice contains the precursors of all of the following except (A) Trypsin (B) Chymotrypsin (C) Carboxypeptidase (D) Aminopeptidase

Description : Pancreatic juice contains the precursors of all of the following except (A) Trypsin (B) Chymotrypsin (C) Carboxypeptidase (D) Aminopeptidase

Last Answer : Answer : D

A common substrate of HGPRTase, APRTase and PRPP glutamyl amidotransferase is (A) Ribose 5 phosphate (B) Phosphoribosyl pyrophosphate (C) Hypoxanthine (D) Adenosine

Description : A common substrate of HGPRTase, APRTase and PRPP glutamyl amidotransferase is (A) Ribose 5 phosphate (B) Phosphoribosyl pyrophosphate (C) Hypoxanthine (D) Adenosine

Last Answer : Answer : B

The first reaction unique to purine nucleotide synthesis is catalysed by (A) PRPP synthetase (B) PRPP glutamyl amido transferase (C) Phosphoribosyl glycinamide synthetase (D) Formyl transferase

Description : The first reaction unique to purine nucleotide synthesis is catalysed by (A) PRPP synthetase (B) PRPP glutamyl amido transferase (C) Phosphoribosyl glycinamide synthetase (D) Formyl transferase

Last Answer : Answer : B

GMP is an allosteric inhibitor of all the following except (A) PRPP synthetase (B) PRPP glutamyl amido synthetase (C) IMP dehydrogenase (D) Adenylosuccinate synthetase

Description : GMP is an allosteric inhibitor of all the following except (A) PRPP synthetase (B) PRPP glutamyl amido synthetase (C) IMP dehydrogenase (D) Adenylosuccinate synthetase

Last Answer : Answer : D

An allosteric inhibitor of PRPP glutamyl amido transferase is (A) AMP (B) ADP (C) GMP (D) All of these

Description : An allosteric inhibitor of PRPP glutamyl amido transferase is (A) AMP (B) ADP (C) GMP (D) All of these

Last Answer : Answer : C

All of the following enzymes are unique to purine nucleotide synthesis except (A) PRPP synthetase (B) PRPP glutamyl amido transferase (C) Adenylosuccinate synthetase (D) IMP dehydrogenase

Description : All of the following enzymes are unique to purine nucleotide synthesis except (A) PRPP synthetase (B) PRPP glutamyl amido transferase (C) Adenylosuccinate synthetase (D) IMP dehydrogenase

Last Answer : Answer : A

In the pathway of de novo synthesis of purine nucleotides, all the following are allosteric enzymes except (A) PRPP glutamyl amido transferase (B) Adenylosuccinate synthetase (C) IMP dehydrogenase (D) Adenylosuccinase

Description : In the pathway of de novo synthesis of purine nucleotides, all the following are allosteric enzymes except (A) PRPP glutamyl amido transferase (B) Adenylosuccinate synthetase (C) IMP dehydrogenase (D) Adenylosuccinase

Last Answer : Answer : D

Estimation of gamma glutamyl transferase is useful to detect which condition?

Description : Estimation of gamma glutamyl transferase is useful to detect which condition?

Last Answer : Alcohol abuse.