Creatine kinase (CK) level in serum is increased in which conditions?

Creatine kinase (CK) level in serum is increased in which conditions? 
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1 Answer

Answer :

Myocardial infarction, muscular dystrophies.
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From the following myocardial infarction, the earliest serum enzyme to rise is (A) Creatine Kinase (B) GOT (C) GPT (D) LDH

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Which of the following serum enzyme rises in myocardial infarction: (A) Creatine kinase (B) GOT (C) LDH (D) All of these

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Creatine kinase is present in all of the following except (A) Liver (B) Myocardium (C) Muscles (D) Brain

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The first enzyme found to have isoenzymes was (A) Alkaline Phosphatase (B) Lactate dehydrogenase (C) Acid Phosphatase (D) Creatine kinase

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On the third day following onset of acute myocardial infarction, which enzyme estimation will have the best predictive value? (A) Serum AST (B) Serum CK (C) Serum ALT (D) Serum LDH

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On the third day of onset of acute myocardial infarction the enzyme elevated is (A) Serum AST (B) Serum CK (C) Serum LDH (D) Serum ALT

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The isozyme CK-MB is specifically increased in the blood of patients who had (A) Skeletal muscle disease (B) Recent myocardial infarction (C) Infective hepatitis (D) Myxoedema

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Gout is characterized by increased plasma levels of (A) Urea (B) Uric acid (C) Creatine (D) Creatinine

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An important finding in Hyperammonemia type II is (A) Increased serum gluatmine level (B) Enlarged liver (C) Mental retardation (D) Increased carbamoyl phosphate synthetase level

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An important finding in glycinuria is (A) Excess excretion of oxalate in the urine (B) Deficiency of enzyme glycinase (C) Significantly increased serum glycine level (D) Defect in renal tubular reabsorption of glycine

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Serum acid phosphatase level is increased in which condition?

Description : Serum acid phosphatase level is increased in which condition?

Last Answer : Prostate carcinoma.

Alkaline phosphatase level in serum is elevated in which conditions?

Description : Alkaline phosphatase level in serum is elevated in which conditions?

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Which one of the following would be expected in pyruvate kinase deficiency? (A) Increased levels of lactate in the R.B.C (B) Hemolytic anemia (C) Decreased ratio of ADP to ATP in R.B.C (D) Increased phosphorylation of Glucose to Glucose-6-phosphate

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The highest energy level is present amongst the following in (A) 1, 3-Biphosphoglycerate (B) Creatine phosphate (C) Carbamoyl phosphate (D) Phosphoenol pyruvate

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Cardiac muscle contains which of the following CK osoenzyme? (A) BB only (B) MM and BB only (C) MM, BB and MB (D) MM and MB only ENZYMES 169

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The CK isoenzymes present in cardiac muscle is (A) BB and MB (B) MM and MB (C) BB only (D) MB only

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When do you estimate total CK and the iso-enzyme?

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What are the origins of the CK iso-enzymes?

Description : What are the origins of the CK iso-enzymes?

Last Answer : Eighty percent of molecules in circulation are MM (CK3) variety of skeletal origin, five percent in circulation are MB (CK2) from heart, one percent from brain (BB or CK1) and fifteen percent CKmt from mitochondria.

What are the iso-enzymes of CK?

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Last Answer : CK is a dimer, the subunits are called B for brain and M for muscle. Therefore, three iso-enzymes are possible.

What is the advantage of CK estimation over LDH estimation to identify myocardial infarction?

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Last Answer : The CK level starts to rise within three hours of infarction. Therefore, CK estimation is very useful to detect early cases, where ECG changes may be ambiguous. The CK level is not increased in hemolysis or in congestive cardiac failure; and therefore CK has an advantage over LDH.

An enzyme of pyrimidine nucleotides biosynthesis regulated at the genetic level by apparently coordinate repression and derepression is (A) Carbamoyl phosphate synthetase (B) Dihydroorotate dehydrogenase (C) Thymidine kinase (D) Deoxycytidine kinase

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Last Answer : Myocardial infarction, hemolytic anemias, muscular dystrophy, carcinomas, leukemias, and any condition which causes necrosis of body cells.

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Last Answer : Answer : B

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The amino acids required for creatine formation: (A) Glycine (B) Arginine (C) Methionine (D) All of these

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