Description : The regulatory enzyme in HMP shunt is (A) Glucose-6-phosphate dehydrogenase (B) 6-Phosphogluconate dehydrogenase (C) Both (A) and (B) (D) None of these
Last Answer : Answer : C
Description : Which of the following enzyme is not involved in HMP shunt? (A) Glyceraldehyde-3-p dehydrogenase (B) Glucose-6-p-dehydrogenase (C) Transketolase (D) Phosphogluconate dehydrogenase
Last Answer : A
Description : Acute hemolytic episode after administration of antimalarial, primaquin, is due to deficiency of the enzyme: (A) 6-Phosphogluconate dehydrogenase (B) Glucose-6-phosphate dehydrogenase (C) Epimerase (D) Transketolase
Last Answer : Answer : B
Description : Transfer of the carbamoyl moiety of carbamoyl phosphate to ornithine is catalysed by a liver mitochondrial enzyme: (A) Carbamoyl phosphate synthetase (B) Ornithine transcarbamoylase (C) N-acetyl glutamate synthetase (D) N-acetyl glutamate hydrolase
Description : The heptose ketose sugar formed as a result of chemical reaction in HMP shunt: (A) Sedoheptulose (B) Galactoheptose (C) Glucoheptose (D) Mannoheptose
Description : Conversion of deoxyuridine monophosphate to thymidine monophosphate is catalysed by the enzyme: (A) Ribonucleotide reductase (B) Thymidylate synthetase (C) CTP synthetase (D) Orotidylic acid decarboxylase
Description : The rate limiting step in catecholamine synthesis is catalysed by (A) Phenylalanine hydroxylase (B) Tyrosine hydroxylase (C) Dopa decarboxylase (D) Phenylethanolamine N-methyl transferase
Description : Conversion of uroporphyrinogen III to coprophyrinogen III is catalysed by the enzyme.: (A) Uroporphyrinogen decarboxylase (B) Coproporphyrinogen oxidase (C) Protoporphyrinogen oxidase (D) Ferrochelatase
Last Answer : Answer : A
Description : UDP glucose is converted to UDP glucurronate, a reaction catalysed by UDP glucose dehydrogenase requires (A) NAD+ (B) FAD (C) NADP (D) FMN
Description : The reaction catalysed by α-ketoglutarate dehydrogenase in the citric acid cycle requires (A) NAD (B) NADP (C) ADP (D) ATP
Description : Riboflavin is a coenzyme in the reaction catalysed by the enzyme (A) Acyl CoA synthetase (B) Acyl CoA dehydrogenase (C) β-Hydroxy acyl CoA (D) Enoyl CoA dehydrogenase
Description : Which enzyme is concerned with transfer of electrons? (A) Desmolase (B) Hydrolase (C) Dehydrogenase (D) Transaminase
Description : Neonatal tyrosinemia is due to deficiency of the enzyme: (A) p-Hydroxyphenylpyruvate hydroxylase (B) Fumarylacetoacetate hydrolase (C) Phenylalanine hydroxylase (D) Tyrosine dehydrogenase
Description : Pancreatic lipose is an enzyme which hydrolyzes facts. It acts as a/an (A) peptidase (B) hydrolase (C) carbohydrates (D) dehydrogenase
Description : One molecule of glucose gives ______ molecules of CO2 in one round of HMP shunt. (A) 6 (B) 1 (C) 2 (D) 3
Last Answer : B
Description : Orotic aciduria type II reflects the deficiency of the enzyme: (A) Orotate phosphoribosyl transferase (B) Orotidylate decarboxylase (C) Dihydroorotase (D) Dihydroorotate dehydrogenase
Description : Orotic aciduria type I reflects the deficiency of enzymes: (A) Orotate phosphoribosyl transferase and orotidylate decarboxylase (B) Dihydroorotate dehydrogenase (C) Dihydroorotase (D) Carbamoyl phosphate synthetase
Description : An enzyme of pyrimidine nucleotide biosynthesis sensitive to allosteric regulation is (A) Aspartate transcarbamoylase (B) Dihydroorotase (C) Dihydroorotate dehydrogenase (D) Orotidylic acid decarboxylase
Description : The enzyme catalyzing conversion of androstenedione to testosterone is a (A) Oxygenase (B) Dehydrogenase (C) Isomerase (D) Decarboxylase
Description : Which one of the following statements is incorrect? (A) Insulin increases glucose phosphorylation (B) Insulin increases glycolysis (C) Insulin augments HMP shunt (D) Insulin promotes gluconeogenesis
Last Answer : Answer : D
Description : Excessive secretion of glucocorticoids raises blood glucose by (A) Decreasing glycogenesis (B) Increasing glycogenolysis (C) Increasing gluconeogenesis (D) Inhibiting HMP shunt
Description : The rate of HMP shunt reactions is (A) Increased by Insulin (B) Increased in diabetes mellitus (C) Increased by glucagons (D) Increased in starvation
Description : The first pentose formed in HMP shunt is (A) Ribose-5-phosphate (B) Ribulose-5-phosphate (C) Xylose-5-phosphate (D)Xylulose-5-phosphate
Description : HMP shunt is present in (A) Erythrocytes (B) Liver (C) Testes (D) All of these
Description : NAD is required as a conenzyme in (A) Citric acid cycle (B) HMP shunt (C) β-Oxidation of fatty acids (D) Both (A) and (C)
Description : NADP is required as a coenzyme in (A) Glycolysis (B) Citric acid cycle (C) HMP shunt (D) Gluconeogenesis
Description : The most important source of reducing equivalents for FA synthesis on the liver is (A) Glycolysis (B) HMP-Shunt (C) TCA cycle (D) Uronic acid pathway
Description : Dehydrogenases involved in HMP shunt are specific for (A) NADP+ (B) NAD+ (C) FAD (D) FMN
Description : Our body can get pentoses from (A) Glycolytic pathway (B) Uromic acid pathway (C) TCA cycle (D) HMP shunt
Last Answer : D
Description : Pentose production is increased in (A) HMP shunt (B) Uromic acid pathway (C) EM pathway (D) TCA cycle
Description : The four membered aldose sugar phosphate formed in HMP shunt pathway is (A) Xylulose P (B) Erythrulose P (C) Erythrose P (D) Ribulose P
Last Answer : C
Description : Two important byproducts of HMP shunt are (A) NADH and pentose sugars (B) NADPH and pentose sugars (C) Pentose sugars and 4 membered sugars (D) Pentose sugars and sedoheptulose
Description : An amphibolic pathway among the following is (A) HMP shunt (B) Glycolysis (C) Citirc acid cycle (D) Gluconeogenesis
Description : Mature erythrocytes do not contain (A) Glycolytic enzymes(B) HMP shunt enzymes (C) Pyridine nucleotide(D) ATP
Description : What is the purpose of HMP shunt pathway?
Last Answer : It generates NADPH.
Description : What is the hormonal control over HMP shunt pathway?
Last Answer : Insulin stimulates the pathway by activating the key enzyme.
Description : What are the tissues in which HMP shunt pathway is significant?
Last Answer : Liver, adipose tissue, RBC, adrenal cortex, ovary, testis, mammary gland, lens.
Description : HMP shunt pathway use how much glucose?
Last Answer : About 10% of glucose molecules per day are entering in this pathway.
Description : Pyruvate dehydrogenase complex and α-ketoglutarate dehydrogenase complex require the following for their oxidative decarboxylation: (A) COASH and Lipoic acid (B) NAD+ and FAD (C) COASH and TPP (D) COASH, TPP,NAD+,FAD, Lipoate
Description : A cofactor in the conversion of dihydroorotate to orotic acid, catalysed by the enzyme dihydroorotate dehydrogenase is (A) FAD (B) FMN (C) NAD (D) NADP
Description : Conversion of inosine monophosphate to xanthine monophosphate is catalysed by (A) IMP dehydrogenase (B) Formyl transferase (C) Xanthine-guanine phosphoribosyl transferase (D) Adenine phosphoribosyl transferase
Description : Conversion of pyruvate into acetyl CoA is catalysed by (A) Pyruvate dehydrogenase (B) Didrolipoyl acetyl transferase (C) Dihydrolipoyl dehydrogenase (D) All the 3 acting in concert
Description : Conversion of fructose to sorbitol is catalysed by the enzyme: (A) Sorbitol dehydrogenase (B) Aldose reductase (C) Fructokinase (D) Hexokinase
Description : The initial step of the citric acid cycle is (A) Conversion of pyruvate to acetyl-CoA (B) Condensation of acetyl-CoA with oxaloacetate (C) Conversion of citrate to isocitrate (D) Formation of α -ketoglutarate catalysed by isocitrate dehydrogenase
Description : The carbon chain of fatty acids is shortened by 2 carbon atoms at a time. This involves successive reactions catalysed by 4-enzymes. These act the following order: (A) Acetyl CoA dehydrogenase, ... CoA dehydrogenase (D) Enoyl hydrase, β-OH acyl CoA dehydrogenase, acyl CoA dehydrogenase, thiolose,
Description : NADPH required for fatty acid synthesis can come from (A) Hexose monophosphate shunt (B) Oxidative decarboxylation of malate (C) Extramitochondrial oxidation of isocitrate (D) All of these
Description : The following enzyme is required for the hexose monophosphate shunt pathway: (A) Glucose-6-phosphatase (B) Phosphorylase (C) Aldolase (D) Glucose-6-phosphate dehydrogenase
Description : A substance that is not an intermediate in the formation of D-glucuronic acid from glucose is (A) Glucoss-1-p (B) 6-Phosphogluconate (C) Glucose-6-p (D) UDP-Glucose
Description : Dehydrogenase enzymes of the hexose monophosphate shunt are (A) NAD+ specific (B) NADP+ specific (C) FAD specific (D) FMN specific
Description : Glucose 6-phosphate is converted to glucose 1-phosphate in a reaction catalysed by the enzyme phosphoglucomutase, which is (A) Phosphorylated (B) Dephosphorylated (C) Phosphorylated-dephosphorylated (D) Phosphorylated-dephosphorylatedrephosphorylated