The regulatory enzyme in HMP shunt is (A) Glucose-6-phosphate dehydrogenase (B) 6-Phosphogluconate dehydrogenase (C) Both (A) and (B) (D) None of these

The regulatory enzyme in HMP shunt is (A) Glucose-6-phosphate dehydrogenase (B) 6-Phosphogluconate dehydrogenase (C) Both (A) and (B) (D) None of these
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Which of the following enzyme is not involved in HMP shunt? (A) Glyceraldehyde-3-p dehydrogenase (B) Glucose-6-p-dehydrogenase (C) Transketolase (D) Phosphogluconate dehydrogenase

Description : Which of the following enzyme is not involved in HMP shunt? (A) Glyceraldehyde-3-p dehydrogenase (B) Glucose-6-p-dehydrogenase (C) Transketolase (D) Phosphogluconate dehydrogenase

Last Answer : A

The decarboxylation reaction in HMP shunt is catalysed by (A) Gluconolactone hydrolase (B) 6-Phosphogluconate dehydrogenase (C) 6-Phosphogluconate decarboxylase (D) Transaldolase

Description : The decarboxylation reaction in HMP shunt is catalysed by (A) Gluconolactone hydrolase (B) 6-Phosphogluconate dehydrogenase (C) 6-Phosphogluconate decarboxylase (D) Transaldolase

Last Answer : Answer : C

Acute hemolytic episode after administration of antimalarial, primaquin, is due to deficiency of the enzyme: (A) 6-Phosphogluconate dehydrogenase (B) Glucose-6-phosphate dehydrogenase (C) Epimerase (D) Transketolase

Description : Acute hemolytic episode after administration of antimalarial, primaquin, is due to deficiency of the enzyme: (A) 6-Phosphogluconate dehydrogenase (B) Glucose-6-phosphate dehydrogenase (C) Epimerase (D) Transketolase

Last Answer : Answer : B

The following enzyme is required for the hexose monophosphate shunt pathway: (A) Glucose-6-phosphatase (B) Phosphorylase (C) Aldolase (D) Glucose-6-phosphate dehydrogenase

Description : The following enzyme is required for the hexose monophosphate shunt pathway: (A) Glucose-6-phosphatase (B) Phosphorylase (C) Aldolase (D) Glucose-6-phosphate dehydrogenase

Last Answer : D

Hemolytic anemia is caused by the deficiency of certain enzymes of the pentose phosphate pathway, the principal enzyme involved is (A) Glucose-6-phosphate dehydrogenase (B) Aldolase (C) Fructose 1, 6-bisphosphatase (D) Phosphohexose isomerase

Description : Hemolytic anemia is caused by the deficiency of certain enzymes of the pentose phosphate pathway, the principal enzyme involved is (A) Glucose-6-phosphate dehydrogenase (B) Aldolase (C) Fructose 1, 6-bisphosphatase (D) Phosphohexose isomerase

Last Answer : Answer : A

The hexose monophosphate pathway includes the enzyme: (A) Maltase dehydrogenase (B) Hexokinase (C) α-Ketoglutarate dehydrogenase (D) Glucose-6-phosphate dehydrogenase

Description : The hexose monophosphate pathway includes the enzyme: (A) Maltase dehydrogenase (B) Hexokinase (C) α-Ketoglutarate dehydrogenase (D) Glucose-6-phosphate dehydrogenase

Last Answer : Answer : D

Which one of the following statements concerning glucose-6-phosphate dehydrogenase deficiency is correct? (A) Young R.B.Cs, particularly reticulocytes, contain the highest enzyme activity cells show less enzyme activity (B) Glucose-6-P Dehydroglucose deficiency leads to disfuction of many tissues (C) G-6-p Dehydroglucose deficiency is due to a single deletion of a large sequence of DNA in the G-6-PD gene (D) G-6-PD deficiency is precipitated by ingestion of drugs such as aspirin

Description : Which one of the following statements concerning glucose-6-phosphate dehydrogenase deficiency is correct? (A) Young R.B.Cs, particularly reticulocytes, contain the highest enzyme activity cells show less enzyme ... PD gene (D) G-6-PD deficiency is precipitated by ingestion of drugs such as aspirin

Last Answer : Answer : A

One molecule of glucose gives ______ molecules of CO2 in one round of HMP shunt. (A) 6 (B) 1 (C) 2 (D) 3

Description : One molecule of glucose gives ______ molecules of CO2 in one round of HMP shunt. (A) 6 (B) 1 (C) 2 (D) 3

Last Answer : B

The first pentose formed in HMP shunt is (A) Ribose-5-phosphate (B) Ribulose-5-phosphate (C) Xylose-5-phosphate (D)Xylulose-5-phosphate

Description : The first pentose formed in HMP shunt is (A) Ribose-5-phosphate (B) Ribulose-5-phosphate (C) Xylose-5-phosphate (D)Xylulose-5-phosphate

Last Answer : Answer : B

The four membered aldose sugar phosphate formed in HMP shunt pathway is (A) Xylulose P (B) Erythrulose P (C) Erythrose P (D) Ribulose P

Description : The four membered aldose sugar phosphate formed in HMP shunt pathway is (A) Xylulose P (B) Erythrulose P (C) Erythrose P (D) Ribulose P

Last Answer : C

Which one of the following statements is incorrect? (A) Insulin increases glucose phosphorylation (B) Insulin increases glycolysis (C) Insulin augments HMP shunt (D) Insulin promotes gluconeogenesis

Description : Which one of the following statements is incorrect? (A) Insulin increases glucose phosphorylation (B) Insulin increases glycolysis (C) Insulin augments HMP shunt (D) Insulin promotes gluconeogenesis

Last Answer : Answer : D

Excessive secretion of glucocorticoids raises blood glucose by (A) Decreasing glycogenesis (B) Increasing glycogenolysis (C) Increasing gluconeogenesis (D) Inhibiting HMP shunt

Description : Excessive secretion of glucocorticoids raises blood glucose by (A) Decreasing glycogenesis (B) Increasing glycogenolysis (C) Increasing gluconeogenesis (D) Inhibiting HMP shunt

Last Answer : Answer : C

HMP shunt pathway use how much glucose?

Description : HMP shunt pathway use how much glucose?

Last Answer : About 10% of glucose molecules per day are entering in this pathway. 

An example of competitive inhibition of an enzyme is the inhibition of a. Succinic dehydrogenase by malonic acid b. Cytochrome oxidase by cyanide c. Hexokinase by glucose-6-phosphate d. Carbonic anhydrase by carbon dioxide

Description : An example of competitive inhibition of an enzyme is the inhibition of a. Succinic dehydrogenase by malonic acid b. Cytochrome oxidase by cyanide c. Hexokinase by glucose-6-phosphate d. Carbonic anhydrase by carbon dioxide

Last Answer : Ans: A

A specific BRCA1 cancer-predisposing gene mutation seems to occur more frequently among women of which descent? a) Ashkanazi Jewish Expression of the BRCA1 gene is an example of inheritance in the development of breast cancer. b) Mediterranean Glucose-6-phosphate dehydrogenase deficiency (G6PD) is a common enzyme abnormality that affects millions of people throughout the world, especially those of Mediterranean, South East Asian, African, Middle Eastern, and Near Eastern origin.

Description : A specific BRCA1 cancer-predisposing gene mutation seems to occur more frequently among women of which descent? a) Ashkanazi Jewish Expression of the BRCA1 gene is an example of ... of treatment for tuberculosis) are at significantly increased risk for developing isoniazid-induced hepatitis.

Last Answer : a) Ashkanazi Jewish Expression of the BRCA1 gene is an example of inheritance in the development of breast cancer.

A substance that is not an intermediate in the formation of D-glucuronic acid from glucose is (A) Glucoss-1-p (B) 6-Phosphogluconate (C) Glucose-6-p (D) UDP-Glucose

Description : A substance that is not an intermediate in the formation of D-glucuronic acid from glucose is (A) Glucoss-1-p (B) 6-Phosphogluconate (C) Glucose-6-p (D) UDP-Glucose

Last Answer : B

Which one of the following enzymes requires a coenzyme derived from the vitamin whose structure is shown below? (A) Enoyl CoA hydratase (B) Phosphofructokinase (C) Glucose-6-phosphatase (D) Glucose-6-phosphate dehydrogenase

Description : Which one of the following enzymes requires a coenzyme derived from the vitamin whose structure is shown below? (A) Enoyl CoA hydratase (B) Phosphofructokinase (C) Glucose-6-phosphatase (D) Glucose-6-phosphate dehydrogenase

Last Answer : Answer : D

Glucose-6-phosphate dehydrogenase is induced by (A) 6-Phosphogluconolactone (B) Glucose-6-phosphate (C) Ribose-5-phosphate (D) Insulin

Description : Glucose-6-phosphate dehydrogenase is induced by (A) 6-Phosphogluconolactone (B) Glucose-6-phosphate (C) Ribose-5-phosphate (D) Insulin

Last Answer : Answer : D

NAD is required as a coenzyme for (A) Malate dehydrogenase (B) Succinate dehydrogenase (C) Glucose-6-phosphate dehydrogenase (D) HMG CoA reductae

Description : NAD is required as a coenzyme for (A) Malate dehydrogenase (B) Succinate dehydrogenase (C) Glucose-6-phosphate dehydrogenase (D) HMG CoA reductae

Last Answer : Answer : A

Conversion of glucose to glucose-6- phosphate in human liver is by (A) Hexokinase only (B) Glucokinase only (C) Hexokinase and glucokinase (D) Glucose-6-phosphate dehydrogenase

Description : Conversion of glucose to glucose-6- phosphate in human liver is by (A) Hexokinase only (B) Glucokinase only (C) Hexokinase and glucokinase (D) Glucose-6-phosphate dehydrogenase

Last Answer : C

What is the manifestation of glucose-6-phosphate dehydrogenase deficiency?

Description : What is the manifestation of glucose-6-phosphate dehydrogenase deficiency?

Last Answer : Drug induced hemolysis and met-hemoglobinemia.

NAD is required as a conenzyme in (A) Citric acid cycle (B) HMP shunt (C) β-Oxidation of fatty acids (D) Both (A) and (C)

Description : NAD is required as a conenzyme in (A) Citric acid cycle (B) HMP shunt (C) β-Oxidation of fatty acids (D) Both (A) and (C)

Last Answer : Answer : D

The “Primaquin sensitivity types of haemolytic anaemia has been found to relate to reduced R.B.C activity of which enzyme? (A) Pyruvate kinase deficiency (B) Glucose-6-phosphatase deficiency (C) Glucose-6-p dehydrogenase deficiency (D) Hexokinase deficiency

Description : The “Primaquin sensitivity types of haemolytic anaemia has been found to relate to reduced R.B.C activity of which enzyme? (A) Pyruvate kinase deficiency (B) Glucose-6-phosphatase deficiency (C) Glucose-6-p dehydrogenase deficiency (D) Hexokinase deficiency

Last Answer : C

An enzyme of pyrimidine nucleotides biosynthesis regulated at the genetic level by apparently coordinate repression and derepression is (A) Carbamoyl phosphate synthetase (B) Dihydroorotate dehydrogenase (C) Thymidine kinase (D) Deoxycytidine kinase

Description : An enzyme of pyrimidine nucleotides biosynthesis regulated at the genetic level by apparently coordinate repression and derepression is (A) Carbamoyl phosphate synthetase (B) Dihydroorotate dehydrogenase (C) Thymidine kinase (D) Deoxycytidine kinase

Last Answer : Answer : A

In glycolytic pathway, iodacetate inhibits the activity of the enzyme: (A) Phosphotriose isomerase (B) Glyceraldehyde-3-phosphate dehydrogenase (C) Pyruvate kinase (D) Phosphofructokinase

Description : In glycolytic pathway, iodacetate inhibits the activity of the enzyme: (A) Phosphotriose isomerase (B) Glyceraldehyde-3-phosphate dehydrogenase (C) Pyruvate kinase (D) Phosphofructokinase

Last Answer : Answer : B

The rate of HMP shunt reactions is (A) Increased by Insulin (B) Increased in diabetes mellitus (C) Increased by glucagons (D) Increased in starvation

Description : The rate of HMP shunt reactions is (A) Increased by Insulin (B) Increased in diabetes mellitus (C) Increased by glucagons (D) Increased in starvation

Last Answer : Answer : A

HMP shunt is present in (A) Erythrocytes (B) Liver (C) Testes (D) All of these

Description : HMP shunt is present in (A) Erythrocytes (B) Liver (C) Testes (D) All of these

Last Answer : Answer : D

NADP is required as a coenzyme in (A) Glycolysis (B) Citric acid cycle (C) HMP shunt (D) Gluconeogenesis

Description : NADP is required as a coenzyme in (A) Glycolysis (B) Citric acid cycle (C) HMP shunt (D) Gluconeogenesis

Last Answer : Answer : C

The most important source of reducing equivalents for FA synthesis on the liver is (A) Glycolysis (B) HMP-Shunt (C) TCA cycle (D) Uronic acid pathway

Description : The most important source of reducing equivalents for FA synthesis on the liver is (A) Glycolysis (B) HMP-Shunt (C) TCA cycle (D) Uronic acid pathway

Last Answer : Answer : B

Dehydrogenases involved in HMP shunt are specific for (A) NADP+ (B) NAD+ (C) FAD (D) FMN

Description : Dehydrogenases involved in HMP shunt are specific for (A) NADP+ (B) NAD+ (C) FAD (D) FMN

Last Answer : A

Our body can get pentoses from (A) Glycolytic pathway (B) Uromic acid pathway (C) TCA cycle (D) HMP shunt

Description : Our body can get pentoses from (A) Glycolytic pathway (B) Uromic acid pathway (C) TCA cycle (D) HMP shunt

Last Answer : D

Pentose production is increased in (A) HMP shunt (B) Uromic acid pathway (C) EM pathway (D) TCA cycle

Description : Pentose production is increased in (A) HMP shunt (B) Uromic acid pathway (C) EM pathway (D) TCA cycle

Last Answer : A

Two important byproducts of HMP shunt are (A) NADH and pentose sugars (B) NADPH and pentose sugars (C) Pentose sugars and 4 membered sugars (D) Pentose sugars and sedoheptulose

Description : Two important byproducts of HMP shunt are (A) NADH and pentose sugars (B) NADPH and pentose sugars (C) Pentose sugars and 4 membered sugars (D) Pentose sugars and sedoheptulose

Last Answer : B

The heptose ketose sugar formed as a result of chemical reaction in HMP shunt: (A) Sedoheptulose (B) Galactoheptose (C) Glucoheptose (D) Mannoheptose

Description : The heptose ketose sugar formed as a result of chemical reaction in HMP shunt: (A) Sedoheptulose (B) Galactoheptose (C) Glucoheptose (D) Mannoheptose

Last Answer : A

An amphibolic pathway among the following is (A) HMP shunt (B) Glycolysis (C) Citirc acid cycle (D) Gluconeogenesis

Description : An amphibolic pathway among the following is (A) HMP shunt (B) Glycolysis (C) Citirc acid cycle (D) Gluconeogenesis

Last Answer : C

Mature erythrocytes do not contain (A) Glycolytic enzymes(B) HMP shunt enzymes (C) Pyridine nucleotide(D) ATP

Description : Mature erythrocytes do not contain (A) Glycolytic enzymes(B) HMP shunt enzymes (C) Pyridine nucleotide(D) ATP

Last Answer : C

What is the purpose of HMP shunt pathway?

Description : What is the purpose of HMP shunt pathway?

Last Answer : It generates NADPH.

What is the hormonal control over HMP shunt pathway?

Description : What is the hormonal control over HMP shunt pathway? 

Last Answer : Insulin stimulates the pathway by activating the key enzyme.

What are the tissues in which HMP shunt pathway is significant?

Description : What are the tissues in which HMP shunt pathway is significant?

Last Answer : Liver, adipose tissue, RBC, adrenal cortex, ovary, testis, mammary gland, lens.

Glucose-6-phosphate dehydrogenase deficiency?

Description : Glucose-6-phosphate dehydrogenase deficiency?

Last Answer : DefinitionGlucose-6-phosphate dehydrogenase (G-6-PD) deficiency is a hereditary condition in which red blood cells break down when the body is exposed to certain drugs or the stress of infection. ... usually brief, because the body continues to produce new red blood cells, which have normal activ

Glucose-6-phosphate dehydrogenase?

Description : Glucose-6-phosphate dehydrogenase?

Last Answer : DefinitionGlucose-6-phosphate dehydrogenase (G6PD) is a type of protein, called an enzyme, that helps red blood cells work properly. The G6PD test looks at the amount (activity) of this substance in a ... attached to the needle. The elastic band is removed from your arm. Once the blood has been c

Of the following hemolytic anemias, which is categorized as inherited? a) Sickle cell anemia Glucose 6-phosphate dehydrogenase deficiency is an inherited abnormality resulting in hemolytic anemia. b) Autoimmune hemolytic anemia Autoimmune hemolytic anemia is an acquired anemia. c) Cold agglutinin disease Cold agglutinin disease is an acquired anemia. d) Hypersplenism Hypersplenism results in an acquired hemolytic anemia.

Description : Of the following hemolytic anemias, which is categorized as inherited? a) Sickle cell anemia Glucose 6-phosphate dehydrogenase deficiency is an inherited abnormality resulting in hemolytic anemia. b ... is an acquired anemia. d) Hypersplenism Hypersplenism results in an acquired hemolytic anemia.

Last Answer : a) Sickle cell anemia Glucose 6-phosphate dehydrogenase deficiency is an inherited abnormality resulting in hemolytic anemia.

The enzyme that converts glucose to glucose-6-phosphate is (A) Phosphatase (B) Hexokinase (C) Phosphorylase (D) Glucose synthetase

Description : The enzyme that converts glucose to glucose-6-phosphate is (A) Phosphatase (B) Hexokinase (C) Phosphorylase (D) Glucose synthetase

Last Answer : Answer : B

A substrate for the enzyme aldolase is (A) galactose-6-phosphate (B) isocitric acid (C) Glucose-1-phosphate (D) Fructose 1, 6 diphosphate

Description : A substrate for the enzyme aldolase is (A) galactose-6-phosphate (B) isocitric acid (C) Glucose-1-phosphate (D) Fructose 1, 6 diphosphate

Last Answer : Answer : D

The enzyme glucose-6-phosphatase which catalyses the conversion of glucose 6-phosphate to glucose is not found in (A) Liver (B) Muscle (C) Intestine (D) Kidney

Description : The enzyme glucose-6-phosphatase which catalyses the conversion of glucose 6-phosphate to glucose is not found in (A) Liver (B) Muscle (C) Intestine (D) Kidney

Last Answer : Answer : B

Glucose 6-phosphate is converted to glucose 1-phosphate in a reaction catalysed by the enzyme phosphoglucomutase, which is (A) Phosphorylated (B) Dephosphorylated (C) Phosphorylated-dephosphorylated (D) Phosphorylated-dephosphorylatedrephosphorylated

Description : Glucose 6-phosphate is converted to glucose 1-phosphate in a reaction catalysed by the enzyme phosphoglucomutase, which is (A) Phosphorylated (B) Dephosphorylated (C) Phosphorylated-dephosphorylated (D) Phosphorylated-dephosphorylatedrephosphorylated

Last Answer : Answer : D

Galactose 1-phosphate is converted to uridine diphosphate galactose, the reaction is catalysed by the enzyme: (A) Glactokinase (B) Galactose 1-phosphate uridyl transferase (C) Uridine diphospho galactose 4-epimerase (D) UDP glucose pyrophosphorylase

Description : Galactose 1-phosphate is converted to uridine diphosphate galactose, the reaction is catalysed by the enzyme: (A) Glactokinase (B) Galactose 1-phosphate uridyl transferase (C) Uridine diphospho galactose 4-epimerase (D) UDP glucose pyrophosphorylase

Last Answer : Answer : B

Glycogen is converted to glucose-1- phosphate by (A) UDPG transferase (B) Branching enzyme (C) Phosphorylase (D) Phosphatase

Description : Glycogen is converted to glucose-1- phosphate by (A) UDPG transferase (B) Branching enzyme (C) Phosphorylase (D) Phosphatase

Last Answer : C

Dehydrogenase enzymes of the hexose monophosphate shunt are (A) NAD+ specific (B) NADP+ specific (C) FAD specific (D) FMN specific

Description : Dehydrogenase enzymes of the hexose monophosphate shunt are (A) NAD+ specific (B) NADP+ specific (C) FAD specific (D) FMN specific

Last Answer : B

The regulatory enzyme for haem synthesis is (A) ALA synthetase (B) haem synthetase (C) Both (A) and (B) (D) None of these

Description : The regulatory enzyme for haem synthesis is (A) ALA synthetase (B) haem synthetase (C) Both (A) and (B) (D) None of these

Last Answer : Answer : A