Description : The regulatory enzyme in HMP shunt is (A) Glucose-6-phosphate dehydrogenase (B) 6-Phosphogluconate dehydrogenase (C) Both (A) and (B) (D) None of these
Last Answer : Answer : C
Description : Acute hemolytic episode after administration of antimalarial, primaquin, is due to deficiency of the enzyme: (A) 6-Phosphogluconate dehydrogenase (B) Glucose-6-phosphate dehydrogenase (C) Epimerase (D) Transketolase
Last Answer : Answer : B
Description : The decarboxylation reaction in HMP shunt is catalysed by (A) Gluconolactone hydrolase (B) 6-Phosphogluconate dehydrogenase (C) 6-Phosphogluconate decarboxylase (D) Transaldolase
Description : Acute hemolytic anemia in person’s sensitive to the Fava beans is due to the deficiency of the enzyme: (A) Pyruvate dehydrogenase (B) G-6-PD (C) Aconitase (D) Transketolase
Description : The following enzyme is required for the hexose monophosphate shunt pathway: (A) Glucose-6-phosphatase (B) Phosphorylase (C) Aldolase (D) Glucose-6-phosphate dehydrogenase
Last Answer : D
Description : In glycolytic pathway, iodacetate inhibits the activity of the enzyme: (A) Phosphotriose isomerase (B) Glyceraldehyde-3-phosphate dehydrogenase (C) Pyruvate kinase (D) Phosphofructokinase
Description : One molecule of glucose gives ______ molecules of CO2 in one round of HMP shunt. (A) 6 (B) 1 (C) 2 (D) 3
Last Answer : B
Description : A substance that is not an intermediate in the formation of D-glucuronic acid from glucose is (A) Glucoss-1-p (B) 6-Phosphogluconate (C) Glucose-6-p (D) UDP-Glucose
Description : Hemolytic anemia is caused by the deficiency of certain enzymes of the pentose phosphate pathway, the principal enzyme involved is (A) Glucose-6-phosphate dehydrogenase (B) Aldolase (C) Fructose 1, 6-bisphosphatase (D) Phosphohexose isomerase
Last Answer : Answer : A
Description : Which of the following enzymes in Glycolytic pathway is inhibited by fluoride? (A) Glyceraldehyde-3-p dehydrogenase (B) Phosphoglycerate kinase (C) Pyruvate kinase (D) Enolase
Description : Which one of the following statements is incorrect? (A) Insulin increases glucose phosphorylation (B) Insulin increases glycolysis (C) Insulin augments HMP shunt (D) Insulin promotes gluconeogenesis
Last Answer : Answer : D
Description : Excessive secretion of glucocorticoids raises blood glucose by (A) Decreasing glycogenesis (B) Increasing glycogenolysis (C) Increasing gluconeogenesis (D) Inhibiting HMP shunt
Description : HMP shunt pathway use how much glucose?
Last Answer : About 10% of glucose molecules per day are entering in this pathway.
Description : Dehydrogenases involved in HMP shunt are specific for (A) NADP+ (B) NAD+ (C) FAD (D) FMN
Last Answer : A
Description : Which one of the following statements concerning glucose-6-phosphate dehydrogenase deficiency is correct? (A) Young R.B.Cs, particularly reticulocytes, contain the highest enzyme activity cells show less enzyme ... PD gene (D) G-6-PD deficiency is precipitated by ingestion of drugs such as aspirin
Description : The “Primaquin sensitivity types of haemolytic anaemia has been found to relate to reduced R.B.C activity of which enzyme? (A) Pyruvate kinase deficiency (B) Glucose-6-phosphatase deficiency (C) Glucose-6-p dehydrogenase deficiency (D) Hexokinase deficiency
Last Answer : C
Description : Which of the following is a substrate for aldolase activity in Glycolytic pathway? (A) Glyceraldehyde-3-p (B) Glucose-6-p (C) Fructose-6-p (D) Fructose1, 6-bisphosphate
Description : The four membered aldose sugar phosphate formed in HMP shunt pathway is (A) Xylulose P (B) Erythrulose P (C) Erythrose P (D) Ribulose P
Description : Which of the following enzymes incorporates inorganic phosphate into the substrate? (A) Phosphoglycerate kinase (B) Glyceraldehyde-3-phosphate dehydrogenase (C) Pyruvate kinase (D) Enolase
Description : One of the enzymes regulating glycolysis is (A) Phosphofructokinase (B) Glyceraldehyde-3-phosphate dehydrogenase (C) Phosphotriose isomerase (D) Phosphohexose isomerase
Description : Enzymes leading to the high energy phosphorylation of substrates during glycolysis include which of the following? (A) Phosphoglycerate kinase (B) Enolase (C) Pyruvate Kinase (D) Glyceraldehyde-3-phosphate dehydrogenase
Description : Fluoride inhibits ______ and arrests glycolysis. (A) Glyceraldehyde-3-phosphate dehydrogenase (B) Aconitase (C) Enolose (D) Succinate dehydrogenase
Description : The hexose monophosphate pathway includes the enzyme: (A) Maltase dehydrogenase (B) Hexokinase (C) α-Ketoglutarate dehydrogenase (D) Glucose-6-phosphate dehydrogenase
Description : Pentose phosphate pathway is of significance because it generates (A) NADPH for reductive synthesis (B) Regenerates glucose 6-phosphate (C) Generates fructose 6-phosphate (D) Forms glyceraldehyde 3-phosphate
Description : The rate of HMP shunt reactions is (A) Increased by Insulin (B) Increased in diabetes mellitus (C) Increased by glucagons (D) Increased in starvation
Description : The first pentose formed in HMP shunt is (A) Ribose-5-phosphate (B) Ribulose-5-phosphate (C) Xylose-5-phosphate (D)Xylulose-5-phosphate
Description : HMP shunt is present in (A) Erythrocytes (B) Liver (C) Testes (D) All of these
Description : NAD is required as a conenzyme in (A) Citric acid cycle (B) HMP shunt (C) β-Oxidation of fatty acids (D) Both (A) and (C)
Description : NADP is required as a coenzyme in (A) Glycolysis (B) Citric acid cycle (C) HMP shunt (D) Gluconeogenesis
Description : The most important source of reducing equivalents for FA synthesis on the liver is (A) Glycolysis (B) HMP-Shunt (C) TCA cycle (D) Uronic acid pathway
Description : Our body can get pentoses from (A) Glycolytic pathway (B) Uromic acid pathway (C) TCA cycle (D) HMP shunt
Description : Pentose production is increased in (A) HMP shunt (B) Uromic acid pathway (C) EM pathway (D) TCA cycle
Description : Two important byproducts of HMP shunt are (A) NADH and pentose sugars (B) NADPH and pentose sugars (C) Pentose sugars and 4 membered sugars (D) Pentose sugars and sedoheptulose
Description : The heptose ketose sugar formed as a result of chemical reaction in HMP shunt: (A) Sedoheptulose (B) Galactoheptose (C) Glucoheptose (D) Mannoheptose
Description : An amphibolic pathway among the following is (A) HMP shunt (B) Glycolysis (C) Citirc acid cycle (D) Gluconeogenesis
Description : Mature erythrocytes do not contain (A) Glycolytic enzymes(B) HMP shunt enzymes (C) Pyridine nucleotide(D) ATP
Description : What is the purpose of HMP shunt pathway?
Last Answer : It generates NADPH.
Description : What is the hormonal control over HMP shunt pathway?
Last Answer : Insulin stimulates the pathway by activating the key enzyme.
Description : What are the tissues in which HMP shunt pathway is significant?
Last Answer : Liver, adipose tissue, RBC, adrenal cortex, ovary, testis, mammary gland, lens.
Description : The transketolase enzyme in the pentose phosphate pathway requires the B vitamin. (A) Pantothenic acid (B) Thiamin (C) Riboflavin (D) Nicotinic acid
Description : What is the clinical significance of transketolase enzyme?
Last Answer : The transketolase reaction is measured in RBCs as an index of the thiamine status of an individual.
Description : An example of competitive inhibition of an enzyme is the inhibition of a. Succinic dehydrogenase by malonic acid b. Cytochrome oxidase by cyanide c. Hexokinase by glucose-6-phosphate d. Carbonic anhydrase by carbon dioxide
Last Answer : Ans: A
Description : A specific BRCA1 cancer-predisposing gene mutation seems to occur more frequently among women of which descent? a) Ashkanazi Jewish Expression of the BRCA1 gene is an example of ... of treatment for tuberculosis) are at significantly increased risk for developing isoniazid-induced hepatitis.
Last Answer : a) Ashkanazi Jewish Expression of the BRCA1 gene is an example of inheritance in the development of breast cancer.
Description : Neonatal tyrosinemia is due to deficiency of the enzyme: (A) p-Hydroxyphenylpyruvate hydroxylase (B) Fumarylacetoacetate hydrolase (C) Phenylalanine hydroxylase (D) Tyrosine dehydrogenase
Description : Albinism is due to deficiency of the enzyme: (A) Phenylalanine hydroxylase (B) Tyrosinase (C) p-Hydroxyphenylpyruvic acid oxidase (D) Tyrosine dehydrogenase
Description : Dehydrogenase enzymes of the hexose monophosphate shunt are (A) NAD+ specific (B) NADP+ specific (C) FAD specific (D) FMN specific
Description : Which one of the following enzymes requires a coenzyme derived from the vitamin whose structure is shown below? (A) Enoyl CoA hydratase (B) Phosphofructokinase (C) Glucose-6-phosphatase (D) Glucose-6-phosphate dehydrogenase
Description : Glucose-6-phosphate dehydrogenase is induced by (A) 6-Phosphogluconolactone (B) Glucose-6-phosphate (C) Ribose-5-phosphate (D) Insulin
Description : NAD is required as a coenzyme for (A) Malate dehydrogenase (B) Succinate dehydrogenase (C) Glucose-6-phosphate dehydrogenase (D) HMG CoA reductae
Description : Conversion of glucose to glucose-6- phosphate in human liver is by (A) Hexokinase only (B) Glucokinase only (C) Hexokinase and glucokinase (D) Glucose-6-phosphate dehydrogenase