A copper containing oxidase is (A) Cytochrome oxidase (B) Flavin mononucleotide (C) Flavin adenine dinucleotide (D) Xanthine oxidase

A copper containing oxidase is (A) Cytochrome oxidase (B) Flavin mononucleotide (C) Flavin adenine dinucleotide (D) Xanthine oxidase
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A molybdenum containing oxidase is (A) Cytochrome oxidase (B) Xanthine oxidase (C) Glucose oxidase (D) L-Amino acid oxidase

Description : A molybdenum containing oxidase is (A) Cytochrome oxidase (B) Xanthine oxidase (C) Glucose oxidase (D) L-Amino acid oxidase

Last Answer : Answer : B

Decarboxylation of α-keto acids requires (A) Thiamine pyrophosphate, FAD, NAD+ (B) Flavin mononucleotide (C) NADP+ (D) NAD+ only

Description : Decarboxylation of α-keto acids requires (A) Thiamine pyrophosphate, FAD, NAD+ (B) Flavin mononucleotide (C) NADP+ (D) NAD+ only

Last Answer : Answer : A

Lesch-Nyhan syndrome, the sex linked recessive disorder is due to the lack of the enzyme: (A) Hypoxanthine-guanine phosphoribosyl transferse (B) Xanthine oxidase (C) Adenine phosphoribosyl transferase (D) Adenosine deaminase

Description : Lesch-Nyhan syndrome, the sex linked recessive disorder is due to the lack of the enzyme: (A) Hypoxanthine-guanine phosphoribosyl transferse (B) Xanthine oxidase (C) Adenine phosphoribosyl transferase (D) Adenosine deaminase

Last Answer : Answer : A

All of the following are iron-containing enzymes except (A) Carbonic anhydrase (B) Catalase (C) Peroxidase (D) Cytochrome oxidase

Description : All of the following are iron-containing enzymes except (A) Carbonic anhydrase (B) Catalase (C) Peroxidase (D) Cytochrome oxidase

Last Answer : Answer : A

Niacin or nicotinic acid is a monocarboxylic acid derivative of (A) Pyridine (B) Pyrimidine (C) Flavin (D) Adenine

Description : Niacin or nicotinic acid is a monocarboxylic acid derivative of (A) Pyridine (B) Pyrimidine (C) Flavin (D) Adenine

Last Answer : Answer : A

Niacin or nicotinic acid is a monocarboxylic acid derivative of (A) Pyridine (B) Pyrimidine (C) Flavin (D) Adenine

Description : Niacin or nicotinic acid is a monocarboxylic acid derivative of (A) Pyridine (B) Pyrimidine (C) Flavin (D) Adenine

Last Answer : (A) Pyridine

Cytochrome C oxidase complex contains cyto-a & `a_(3)` and two copper centres.

Description : Cytochrome C oxidase complex contains cyto-a & `a_(3)` and two copper centres.

Last Answer : Cytochrome C oxidase complex contains cyto-a & `a_(3)` and two copper centres.

Cytochrome C oxidase complex contains cyto-a & `a_(3)` and two copper centres.

Description : Cytochrome C oxidase complex contains cyto-a & `a_(3)` and two copper centres.

Last Answer : Cytochrome C oxidase complex contains cyto-a & `a_(3)` and two copper centres.

Copper is associated with _____ mitochondria' enzymes. (1) Cytochrome oxidase (2) Succinic dehydrogenase (3) Catalase (4) Acid phosphatase

Description : Copper is associated with _____ mitochondria' enzymes. (1) Cytochrome oxidase (2) Succinic dehydrogenase (3) Catalase (4) Acid phosphatase

Last Answer : (1) Cytochrome oxidase Explanation: Copper is involved in normalized function of many enzymes, such as cytochrome oxidase, which is complex IV in mitochondrial electron ... transportation, antioxidant and free radical scavenging and neutralization, and neurotransmitter synthesis, respectively.

Copper is associated with ____ mitochondrial enzymes. (1) Cytochrome oxidase (2) Succinic dehydrogenase (3) Catalase (4) Acid phosphatase

Description : Copper is associated with ____ mitochondrial enzymes. (1) Cytochrome oxidase (2) Succinic dehydrogenase (3) Catalase (4) Acid phosphatase

Last Answer : Cytochrome oxidase

A drug which prevents uric acid synthesis by inhibiting the enzyme Xanthine oxidase is (A) Aspirin (B) Allopurinal (C) Colchicine (D) Phenyl benzoate

Description : A drug which prevents uric acid synthesis by inhibiting the enzyme Xanthine oxidase is (A) Aspirin (B) Allopurinal (C) Colchicine (D) Phenyl benzoate

Last Answer : Answer : B

Hypouricaemia can occur in (A) Xanthine oxidase deficiency (B) Psoriasis (C) Leukaemia (D) None of these

Description : Hypouricaemia can occur in (A) Xanthine oxidase deficiency (B) Psoriasis (C) Leukaemia (D) None of these

Last Answer : Answer : A

Mammals other than higher primates do not suffer from gout because they (A) Lack xanthine oxidase (B) Lack adenosine deaminase (C) Lack purine nucleoside phosphorylase (D) Possess uricase

Description : Mammals other than higher primates do not suffer from gout because they (A) Lack xanthine oxidase (B) Lack adenosine deaminase (C) Lack purine nucleoside phosphorylase (D) Possess uricase

Last Answer : Answer : D

All of the following statements about allopurinol are true except (A) It is a structural analogue of uric acid (B) It can prevent uric acid stones in the kidneys (C) It increases the urinary excretion of xanthine and hypoxanthine (D) It is a competitive inhibitor of xanthine oxidase

Description : All of the following statements about allopurinol are true except (A) It is a structural analogue of uric acid (B) It can prevent uric acid stones in the kidneys (C) It increases the urinary excretion of xanthine and hypoxanthine (D) It is a competitive inhibitor of xanthine oxidase

Last Answer : Answer : A

Enzymic deficiency in β-aminoisobutyric aciduria is (A) Adenosine deaminase (B) Xanthine oxidase (C) Orotidylate decarboxylase (D) Transaminase

Description : Enzymic deficiency in β-aminoisobutyric aciduria is (A) Adenosine deaminase (B) Xanthine oxidase (C) Orotidylate decarboxylase (D) Transaminase

Last Answer : Answer : D

An autosomal recessive disorder, xanthinuria is due to deficiency of the enzymes: (A) Adenosine deaminase (B) Xanthine oxidase (C) HGPRTase (D) Transaminase

Description : An autosomal recessive disorder, xanthinuria is due to deficiency of the enzymes: (A) Adenosine deaminase (B) Xanthine oxidase (C) HGPRTase (D) Transaminase

Last Answer : Answer : B

In humans purine are catabolised to uric acid due to lack of the enzyme: (A) Urease (B) Uricase (C) Xanthine oxidase (D) Guanase

Description : In humans purine are catabolised to uric acid due to lack of the enzyme: (A) Urease (B) Uricase (C) Xanthine oxidase (D) Guanase

Last Answer : Answer : B

Molybdenum is a cofactor for (A) Xanthine oxidase (B) Aldehyde oxidase (C) Sulphite oxidase (D) All of these

Description : Molybdenum is a cofactor for (A) Xanthine oxidase (B) Aldehyde oxidase (C) Sulphite oxidase (D) All of these

Last Answer : Answer : D

Iron is present in all the following except (A) Peroxidase (B) Xanthine oxidase (C) Aconitase (D) Fumarase

Description : Iron is present in all the following except (A) Peroxidase (B) Xanthine oxidase (C) Aconitase (D) Fumarase

Last Answer : Answer : D

Schardinger’s enzyme is (A) Lactate dehydrogenase (B) Xanthine dehydrogenase (C) Uric oxidase (D) L amino acid dehydrogenase

Description : Schardinger’s enzyme is (A) Lactate dehydrogenase (B) Xanthine dehydrogenase (C) Uric oxidase (D) L amino acid dehydrogenase

Last Answer : Answer : B

Physostigmine is a competitive inhibitor of (A) Xanthine oxidase (B) Cholinesterase (C) Carbonic anhydrase (D) Monoamine oxidase

Description : Physostigmine is a competitive inhibitor of (A) Xanthine oxidase (B) Cholinesterase (C) Carbonic anhydrase (D) Monoamine oxidase

Last Answer : Answer : B

An enzyme which uses hydrogen acceptor as substrate is (A) Xanthine oxidase (B) Aldehyde oxidase (C) Catalase (D) Tryptophan oxygenase

Description : An enzyme which uses hydrogen acceptor as substrate is (A) Xanthine oxidase (B) Aldehyde oxidase (C) Catalase (D) Tryptophan oxygenase

Last Answer : Answer : C

Insulin degradation of disulfide bond formation is effected by (A) Pyruvate dehydrogenase (B) Xylitol reductase (C) Gutathione reductase (D) Xanthine oxidase

Description : Insulin degradation of disulfide bond formation is effected by (A) Pyruvate dehydrogenase (B) Xylitol reductase (C) Gutathione reductase (D) Xanthine oxidase

Last Answer : Answer : C

A drug which prevents uric acid synthesis by inhibiting the enzyme xanthine oxidase is (A) Aspirin (B) Allopurinol (C) Colchicine (D) Probenecid

Description : A drug which prevents uric acid synthesis by inhibiting the enzyme xanthine oxidase is (A) Aspirin (B) Allopurinol (C) Colchicine (D) Probenecid

Last Answer : B

Nitrosamine can deaminate (A) Cytosine to form uracil (B) Adenine to form xanthine (C) Guanine to form hypoxanthine (D) All of these

Description : Nitrosamine can deaminate (A) Cytosine to form uracil (B) Adenine to form xanthine (C) Guanine to form hypoxanthine (D) All of these

Last Answer : Answer : A

An alternate substrate for orotate phosphoribosyl transferase is (A) Allopurinol (B) Xanthine (C) Hypoxanthine (D) Adenine

Description : An alternate substrate for orotate phosphoribosyl transferase is (A) Allopurinol (B) Xanthine (C) Hypoxanthine (D) Adenine

Last Answer : Answer : D

Conversion of inosine monophosphate to xanthine monophosphate is catalysed by (A) IMP dehydrogenase (B) Formyl transferase (C) Xanthine-guanine phosphoribosyl transferase (D) Adenine phosphoribosyl transferase

Description : Conversion of inosine monophosphate to xanthine monophosphate is catalysed by (A) IMP dehydrogenase (B) Formyl transferase (C) Xanthine-guanine phosphoribosyl transferase (D) Adenine phosphoribosyl transferase

Last Answer : Answer : A

A copper containing cytochrome is (A) Cytochrome a (B) Cytochrome P-450 (C) Cytochrome a3 (D) None of these

Description : A copper containing cytochrome is (A) Cytochrome a (B) Cytochrome P-450 (C) Cytochrome a3 (D) None of these

Last Answer : Answer : C

All the following statements about ceruloplasmin are correct except (A) It is a copper-containing protein (B) It possesses oxidase activity (C) It is synthesised in intestinal mucosa (D) Its plasma level is decreased inWilson’s disease

Description : All the following statements about ceruloplasmin are correct except (A) It is a copper-containing protein (B) It possesses oxidase activity (C) It is synthesised in intestinal mucosa (D) Its plasma level is decreased inWilson’s disease

Last Answer : Answer : C

Activity of cytochrome oxidase is inhibited by (A) Sulphite (B) Sulphate (C) Arsenite (D) Cyanide

Description : Activity of cytochrome oxidase is inhibited by (A) Sulphite (B) Sulphate (C) Arsenite (D) Cyanide

Last Answer : Answer : D

Cytochrome oxidase contains (A) Cu2+ and Zn2+ (B) Cu2+ and Fe2+ (C) Cu2+ and Mn2+ (D) Cu2+

Description : Cytochrome oxidase contains (A) Cu2+ and Zn2+ (B) Cu2+ and Fe2+ (C) Cu2+ and Mn2+ (D) Cu2+

Last Answer : Answer : B

The pentose phosphate pathway protects erythrocytes against hemolysis by assisting the enzyme: (A) Superoxide dismutase (B) Catalase (C) Glutathionic peroxidase (D) Cytochrome oxidase ENZYMES 149

Description : The pentose phosphate pathway protects erythrocytes against hemolysis by assisting the enzyme: (A) Superoxide dismutase (B) Catalase (C) Glutathionic peroxidase (D) Cytochrome oxidase ENZYMES 149

Last Answer : Answer : C

The enzyme using some other substance, not oxygen as hydrogen acceptor is (A) Tyrosinase (B) Succinate dehydrogenase (C) Uricase (D) Cytochrome oxidase

Description : The enzyme using some other substance, not oxygen as hydrogen acceptor is (A) Tyrosinase (B) Succinate dehydrogenase (C) Uricase (D) Cytochrome oxidase

Last Answer : Answer : B

An enzyme catalyzing oxidoreduction, using oxygen as hydrogen acceptor is (A) Cytochrome oxidase (B) Lactate dehydrogenase (C) Malate dehydrogenase (D) Succinate dehydrogenase

Description : An enzyme catalyzing oxidoreduction, using oxygen as hydrogen acceptor is (A) Cytochrome oxidase (B) Lactate dehydrogenase (C) Malate dehydrogenase (D) Succinate dehydrogenase

Last Answer : Answer : A

Example of an extracellular enzyme is (A) Lactate dehydrogenase (B) Cytochrome oxidase (C) Pancreatic lipase (D) Hexokinase

Description : Example of an extracellular enzyme is (A) Lactate dehydrogenase (B) Cytochrome oxidase (C) Pancreatic lipase (D) Hexokinase

Last Answer : Answer : C

Which of the following is located in the mitochondria? (A) Cytochrome oxidase (B) Succinate dehydrogenase (C) Dihydrolipoyl dehydrogenase (C) All of these

Description : Which of the following is located in the mitochondria? (A) Cytochrome oxidase (B) Succinate dehydrogenase (C) Dihydrolipoyl dehydrogenase (C) All of these

Last Answer : D

Which of the following statements are true of oxidants? A. In addition to their pathophysiologic roles in inflammation, injury, and infection, oxidants also have physiologic roles. B. Oxidants may be generated from activated neutrophils and during reperfusion following a period of ischemia. C. The deleterious effects of oxidants include lipid peroxidation and cell membrane damage, oxidative damage to DNA, and inhibition of adenosine triphosphate (ATP) synthesis. D. The mechanism of ischemia-reperfusion injury involved the catalytic production of superoxide anion (O 2•) by the enzyme xanthine oxidase.

Description : Which of the following statements are true of oxidants? A. In addition to their pathophysiologic roles in inflammation, injury, and infection, oxidants also have physiologic roles. B. Oxidants may ... involved the catalytic production of superoxide anion (O 2 ) by the enzyme xanthine oxidase.

Last Answer : Answer: ABCD DISCUSSION: Oxidants are reactive oxygen metabolites that have both physiologic and pathophysiologic roles. As potent oxidizing agents, oxidants are involved in cytochrome P ... leukocyte infiltration and activation, causing further tissue damage by the release of cytotoxic proteases

Which of the following enzymes is ultimately responsible for the production of prostaglandins associated with inflammatory reactions? (a) Phospholipase (b) Lipoxygenase (c) Cyclooxygenase-I (d) Cyclooxygenase II (e) Xanthine oxidase

Description : Which of the following enzymes is ultimately responsible for the production of prostaglandins associated with inflammatory reactions? (a) Phospholipase (b) Lipoxygenase (c) Cyclooxygenase-I (d) Cyclooxygenase II (e) Xanthine oxidase

Last Answer : Ans: D

Albinism is a congenital disorder resulting from the lack of which enzyme? (a) Tyrosinase (b) Xanthine oxidase (c) Catalase (d) Fructokinase

Description : Albinism is a congenital disorder resulting from the lack of which enzyme? (a) Tyrosinase (b) Xanthine oxidase (c) Catalase (d) Fructokinase

Last Answer : (a) Tyrosinase

Thioguanine differs from mercaptopurine in that: A. It is not metabolized by xanthine oxidase B. It does not cause hyperuricemia C. Its dose need not be reduced when allopurinol is given concurrently D. Both ‘A’ and ‘C’ are correc

Description : Thioguanine differs from mercaptopurine in that: A. It is not metabolized by xanthine oxidase B. It does not cause hyperuricemia C. Its dose need not be reduced when allopurinol is given concurrently D. Both ‘A’ and ‘C’ are correc

Last Answer : D. Both ‘A’ and ‘C’ are correct

Choose the correct statement about allopurinol: A. It is a purine antimetabolite with antineoplastic activity B. It is a competitive inhibitor of xanthine oxidase C. It is inactive itself, but its metabolite alloxanthine is a competitive inhibitor of xanthine oxidase D. Both allopurinol as well as its metabolite alloxanthine are noncompetitive inhibitors of xanthine oxidase

Description : Choose the correct statement about allopurinol: A. It is a purine antimetabolite with antineoplastic activity B. It is a competitive inhibitor of xanthine oxidase C. It is inactive itself ... D. Both allopurinol as well as its metabolite alloxanthine are noncompetitive inhibitors of xanthine oxidase

Last Answer : B. It is a competitive inhibitor of xanthine oxidase

A drug which prevents uric acid synthesis by inhibiting the enzyme xanthine oxidase is (A) Aspirin (B) Allopurinol (C) Colchicine (D) Probenecid

Description : A drug which prevents uric acid synthesis by inhibiting the enzyme xanthine oxidase is (A) Aspirin (B) Allopurinol (C) Colchicine (D) Probenecid

Last Answer : (B) Allopurinol

An example of competitive inhibition of an enzyme is the inhibition of a. Succinic dehydrogenase by malonic acid b. Cytochrome oxidase by cyanide c. Hexokinase by glucose-6-phosphate d. Carbonic anhydrase by carbon dioxide

Description : An example of competitive inhibition of an enzyme is the inhibition of a. Succinic dehydrogenase by malonic acid b. Cytochrome oxidase by cyanide c. Hexokinase by glucose-6-phosphate d. Carbonic anhydrase by carbon dioxide

Last Answer : Ans: A

Which of the following is located in the mitochondria? (A) Cytochrome oxidase (B) Succinate dehydrogenase (C) Dihydrolipoyl dehydrogenase (D) All of these

Description : Which of the following is located in the mitochondria? (A) Cytochrome oxidase (B) Succinate dehydrogenase (C) Dihydrolipoyl dehydrogenase (D) All of these

Last Answer : (D) All of these

This compound has a double helical structure. (A) Deoxyribonucleic acid (B) RNA (C) Flavine-adevine dinucleotide (D) Nicotinamide adamine dinucleotide

Description : This compound has a double helical structure. (A) Deoxyribonucleic acid (B) RNA (C) Flavine-adevine dinucleotide (D) Nicotinamide adamine dinucleotide

Last Answer : Answer : A

Vitamins that function as dinucleotide derivatives include all the following except (A) Thiamine (B) Niacin (C) Nicotinate (D) Vitamin B2

Description : Vitamins that function as dinucleotide derivatives include all the following except (A) Thiamine (B) Niacin (C) Nicotinate (D) Vitamin B2

Last Answer : Answer : A

The iron containing nonporphyrin is (A) Hemosiderin (B) Catalase (C) Cytochrome C (D) Peroxidase

Description : The iron containing nonporphyrin is (A) Hemosiderin (B) Catalase (C) Cytochrome C (D) Peroxidase

Last Answer : Answer : A

Hybridoma cells are selected by culturing them in a medium containing (A) Adenine, guanine, cytosine and thymine (B) Adenine, guanine, cytosine and uracil (C) Hypoxanthine, aminopterin and thymine (D) Hypoxanthine, aminopterin and thymidine

Description : Hybridoma cells are selected by culturing them in a medium containing (A) Adenine, guanine, cytosine and thymine (B) Adenine, guanine, cytosine and uracil (C) Hypoxanthine, aminopterin and thymine (D) Hypoxanthine, aminopterin and thymidine

Last Answer : Answer : D

A deficiency of copper effects the formation of normal collagen by reducing the activity of which of the following enzyme? (A) Prolyl hydroxylase (B) Lysyl oxidase (C) Lysyl hydroxylase (D) Glucosyl transferase

Description : A deficiency of copper effects the formation of normal collagen by reducing the activity of which of the following enzyme? (A) Prolyl hydroxylase (B) Lysyl oxidase (C) Lysyl hydroxylase (D) Glucosyl transferase

Last Answer : Answer : B

The deficiency of copper decreases the activity of the enzyme: (A) Lysine oxidase (B) Lysine hydroxylase (C) Tyrosine oxidase (D) Proline hydroxylase

Description : The deficiency of copper decreases the activity of the enzyme: (A) Lysine oxidase (B) Lysine hydroxylase (C) Tyrosine oxidase (D) Proline hydroxylase

Last Answer : Answer : A