Description : The characteristic urinary finding in acute intermittent porphyria is (A) Increased quantity of uroporphyrin (B) Increased quantity of coproporphyrin I (C) Increased quantity of coproporphyrin III (D) Massive quantities of porphobilinogen
Last Answer : Answer : D
Description : The characteristic urinary finding in porphyria cutanea tarda is (A) Increased quantity of porphobilinogen (B) Increased quantity of red cell protoporphyrin (C) Increased quantity of uroporphyrin (D) Increased quantity of δ-ALA
Last Answer : Answer : C
Description : During breakdown of haem, the methenyl bridge between the following two pyrrole rings is broken: (A) I and II (B) II and III (C) III and IV (D) IV and I
Last Answer : Answer : A
Description : In the biosynthesis of the iron protoporphyrin, the product of the condensation between succinyl-CoA and glycine is (A) α-Amino β-ketoadipic acid (B) δ-Aminolevulinate (C) Hydroxymethylbilane (D) Uroporphyrinogen I
Description : Which of the following is a characteristic feature of acute intermittent porphyria? 1) autosomal recessive inheritance 2) excessive faecal protoporphyrin excretion 3) excessive urinary porphobilinigoen between acute attacks 4) hypernatraemia during attacks 5) photosensitivity
Last Answer : Answers-3 Features of acute intermittent porphyria include urinary porphobilinogen excretion raised between attacks, hyponatraemia during an acute attack and autosomal dominant inheritance.
Description : Haem synthetase is congenitally deficient in (A) Congenital erythropoietic porphyria (B) Protoporphyria (C) Hereditary coproporphyria (D) Variegate porphyria
Last Answer : Answer : B
Description : Regulation of haem synthesis occurs by (A) Covalent modification (B) Repression - derepression (C) Induction (D) Allosteric regulation
Description : The regulatory enzyme for haem synthesis is (A) ALA synthetase (B) haem synthetase (C) Both (A) and (B) (D) None of these
Description : Which of the following coenzyme is required for porphyrin synthesis? (A) Coenzyme A (B) Pyridoxal phosphate (C) Both (A) and (B) (D) None of these
Description : An amino acid required for porphyrin synthesis is (A) Proline (B) Glycine (C) Serine (D) Histidine
Description : The number of molecules of porphobilinogen required for the formation of a tetrapyrrole i.e., a porphyrin is (A) 1 (B) 2 (C) 3 (D) 4
Description : In mammalian liver the rate controlling enzyme in porphyrin biosynthesis is (A) ALA synthase (B) ALA hydratase (C) Uroporphyrinogen I synthase (D) Uroporphyrinogen III cosynthase
Description : Porphyrin synthesis is inhibited in (A) Mercury poisoning (B) Lead poisoning (C) Manganese poisoning (D) Barium poisoning
Description : Assertion `:-` Haemoglobin can not get saturated with oxygen more than `97%`. Reason `:-` With a rise in `PO_(2)`, the affinity between `O_(2)` & haem
Last Answer : Assertion `:-` Haemoglobin can not get saturated with oxygen more than `97%`. Reason `:-` With a ... False. D. If both Assertion & Reason are false.
Description : Chlorophyll is porphyrin containing - (1) magnesium (2) iron (3) calcium (4) (4) tin
Last Answer : (1) magnesium Explanation: Chlorophyll are greenish pigment which contain a porphyrin ring. This is a stable ring-shaped molecule around which electrons are free to migrate. Magnesium is central atom in porphyrin structure of chlorophyll.
Description : Cytochrome is (a) metallo flavo protein (b) Fe containing porphyrin pigment (c) glycoprotein (d) lipid.
Last Answer : (b) Fe containing porphyrin pigment
Description : Which element is located at the centre of the porphyrin ring in chlorophyll? (a) Calcium (b) Magnesium (c) Potassium (d) Manganese
Last Answer : (b) Magnesium
Description : Primase activity is present in (A) DNA polymerase II (B) DNA polymerase α (C) DNA polymerase β (D) DNA polymerase δ
Description : Reverse transcriptase activity is present in the eukaryotic: (A) DNA polymerase α (B) DNA polymerase γ (C) Telomerase (D) DNA polymerase II
Description : MHC class II proteins are present on the surface of (A) All cells (B) B lymphocytes only (C) Macrophages only (D) Macrophages and B lymphocytes
Description : Apolipoprotiens C-I, C-II and C-III are present in all of the following except (A) Chylomicrons (B) VLDL (C) LDL (D) HDL
Description : Apolipoproteins C-I, C-II and C-III are present in (A) Chylomicrons (B) VLDL (C) HDL (D) All of these
Description : Apolipoproteins A-I and A-II are present in (A) LDL only (B) LDL and VLDL (C) HDL only (D) HDL and chylomicrons