Description : The characteristic urinary finding in acute intermittent porphyria is (A) Increased quantity of uroporphyrin (B) Increased quantity of coproporphyrin I (C) Increased quantity of coproporphyrin III (D) Massive quantities of porphobilinogen
Last Answer : Answer : D
Description : The probable cause of porphyria cutanea tarda is deficiency of (A) Uroporphyrinogen oxidase (B) Coproporphyrinogen oxidase (C) Protoporphyrinogen oxidase (D) Uroporphyrinogen I synthase MINERAL METABOLISM 185
Last Answer : Answer : A
Description : Which of the following is a characteristic feature of acute intermittent porphyria? 1) autosomal recessive inheritance 2) excessive faecal protoporphyrin excretion 3) excessive urinary porphobilinigoen between acute attacks 4) hypernatraemia during attacks 5) photosensitivity
Last Answer : Answers-3 Features of acute intermittent porphyria include urinary porphobilinogen excretion raised between attacks, hyponatraemia during an acute attack and autosomal dominant inheritance.
Description : The porphyrin present in haem is (A) Uroporphyrin (B) Protoporphyrin I (C) Coproporphyrin (D) Protoporphyrin II
Description : In the biosynthesis of the iron protoporphyrin, the product of the condensation between succinyl-CoA and glycine is (A) α-Amino β-ketoadipic acid (B) δ-Aminolevulinate (C) Hydroxymethylbilane (D) Uroporphyrinogen I
Description : The enzyme involved in variegate porphyria is (A) Protoporphyrinogen oxidase (B) Coproporphyrinogen oxidase (C) Uroporphyrinogen decarboxylase (D) ALA decarboxylase
Description : Acute intermittent porphyria (paraoxymal porphyria) is caused due to deficiency of (A) Uroporphyrinogen I synthase (B) ALA synthase (C) Coproporphyrinogen oxidase (D) Uroporphyrinogen decarboxylase
Description : Goitrogenic substance present in cabbage is (A) 5-vinyl-2 thio oxalzolidone (B) Pyridine-3-carboxylic acid (C) 3-Hydroxy-4, 5-dihydroxymethyl1–2-methyl pyridine (D) δ-ALA dehydratase
Description : The condensation of 2 molecules of δ-aminolevulinate dehydratase contains (A) ALA synthase (B) ALA hydratase (C) Uroporphyrinogen synthase I (D) Uroporphyrinogen synthase III
Last Answer : Answer : B
Description : The number of molecules of porphobilinogen required for the formation of a tetrapyrrole i.e., a porphyrin is (A) 1 (B) 2 (C) 3 (D) 4
Description : An important finding in Histidinemia is (A) Impairment of conversion of α-Glutamate to α-ketoglutarate (B) Speech defect (C) Decreased urinary histidine level (D) Patients can not be treated by diet
Description : A characteristic of pheochromocytoma is elevated urinary excretion of (A) Dopamine (B) Tyrosine (C) Vinylmandelic acid (D) Phenylalanine
Last Answer : Answer : C
Description : Haem synthetase is congenitally deficient in (A) Congenital erythropoietic porphyria (B) Protoporphyria (C) Hereditary coproporphyria (D) Variegate porphyria
Description : Main symptoms of congenital erythropoietic porphyria is (A) Yellowish teeth (B) Photosensitivity (C) Abdominal pain (D) Brownish urine
Description : The enzyme involved in congenial erythropoietic porphyria is (A) Uroporphyrinogen I synthase (B) Uroporphyrinogen III cosynthase (C) Protoporphyrinogen oxidase (D) Ferrochelatase
Description : The major symptom of acute intermittent porphyria includes (A) Abdominal pain (B) Photosensitivity (C) No neuropsychiatric signs (D) Dermatitis
Description : Hypervitaminosis K in neonates may cause (A) Porphyria (B) Jaundice (C) Pellagra (D) Prolonged bleeding
Description : Urinary water loss is increased in (A) Diabetes mellitus (B) Diabetes insipidus (C) Chronic glomerulonephritis (D) All of these
Description : Increased urinary excretion of orotic acid can occur in deficiency of (A) Orotate phosphoribosyl transferase (B) OMP decarboxylase (C) Mitochondrial ornithine transcarbamoylase (D) Any of the above
Description : Urinary excretion of vanillyl madelic acid is increased in (A) Phaeochromocytoma (B) Cushing’s syndrome (C) Carcinoid syndrome (D) Aldosteronism
Description : In Vitamin D poisoning (hyper-vitaminosis) (A) Both serum and urinary “Ca” (B) The serum Ca is low and urinary calcium high (C) The serum “Ca” is increased and urinary “Ca” is normal (D) Both serum and urinary “Ca” are low
Description : Pentosuria is a rare hereditary disease is characterized by increased urinary excretion of (A) L-xylulose (B) Xylitol (C) Xylulose 5-phosphate (D) Ribose 5-phosphate
Description : Folic acid deficiency can be diagnosed by increased urinary excretion of (A) Methylmalonate (B) Figlu (C) Cystathionine (D) Creatinine
Description : In obstructive jaundice, urinary bilirubin is (A) Absent (B) Increased (C) Present (D) Present in small amount
Description : Increased urinary indole acetic acid is diagnostic of (A) Maple syrup urine disease (B) Hartnup disease (C) Homocystinuia (D) Phenylketonuria
Description : All the following are true about phenylketonuria except (A) Deficiency of phenylalanine hydroxylase (B) Mental retardation (C) Increased urinary excretion of p-hydroxyphenyl pyruvic acid (D) Decrease serotonin formation
Description : All the following statements about phenylketonuria are correct except (A) Phenylalanine cannot be converted into tyrosine (B) Urinary excretion of phenylpyruvate and phenyllactate is increased (C) It ... diet (D) It leads to decreased synthesis of thyroid hormones, catecholamines and melanin
Description : Which of the following is true concerning a 68 year old male with type 2 diabetes diagnosed with type IV renal tubal acidosis? 1) Aminoaciduria would be expected. 2) Fludrocortisone treatment is effective ... 4) Increased urinary bicarbonate would be expected. 5) Normal renal handling of K+ and H+
Last Answer : Answers-2 H+ secretion, sodium reabsorption and ammonia production diminishes. RTA 4 is in effect hyporeninaemic hypoaldosteronism or failure of aldosterone action and thus helped treated with ... particularly. Aminoaciduria and increased urine bicarbonate are features of RTA types 1 and 2.
Description : Tricorrhexis nodosa is a characteristic finding of (A) Argininosuccinic aciduria (B) Citrullinemia (C) Phenylketonuria (D) Hyperargininemia
Description : Figure shows human urinary system with structures labelled A to D. Select option which correctly identifies them and gives their characteristic and/ or functions. (a) C - Medulla - inner zone of ... B - Pelvis - broad funnel shaped space inner to hilum, directly connected to loops of Henle
Last Answer : (c) A - Adrenal gland - located at the anterior part of kidney. Secrete catecholamines which stimulate glycogen breakdown.
Description : Does anyone else on here have or know about Acute Intermittent Porphyria?
Last Answer : answer:Pee in a covered glass, leave it outside on a sunny day – all day. If it turns purple, you’ve got it. Seriously. Not foolproof, but you know… you could always GO TO YOUR DOCTOR IF YOU SUSPECT A SERIOUS CONDITION. What makes you think you have it?
Description : Porphyria?
Last Answer : DefinitionPorphyrias are a group of rare disorders passed down through families, in which an important part of hemoglobin, called heme, is not made properly. Heme is also found in myoglobin, a ... are many different forms of porphyria. The most common type is porphyria cutanea tarda (PCT).Dru
Description : Which of the following terms refers to enlarged, red, and tender lymph nodes? a) Lymphadenitis Acute lymphadenitis is demonstrated by enlarged, red and tender lymph nodes. b) Lymphangitis ... refers to a condition in which chronic swelling of the extremity recedes only slightly with elevation.
Last Answer : a) Lymphadenitis Acute lymphadenitis is demonstrated by enlarged, red and tender lymph nodes.
Description : Synthesis of RNA molecule is terminated by a signal which is recognised by (A) α-factor (B) β-factor (C) δ-factor (D) ρ
Description : The mammalian DNA polymerase involved in error correction is (A) DNA polymerase α (B) DNA polymerase β (C) DNA polymerase γ (D) DNA polymerase δ
Description : Primase activity is present in (A) DNA polymerase II (B) DNA polymerase α (C) DNA polymerase β (D) DNA polymerase δ
Description : After termination of the synthesis of RNA molecule, the core enzymes separate from the DNA template. The core enzymes then recognize a promoter at which the synthesis of a new RNA molecule commences, with the assistance of (A) Rho (ρ) factor (B) δ factor (C) β factor (D) σ factor
Description : Termination of the synthesis of the RNA molecule is signaled by a sequence in the template strand of the DNA molecule, a signal that is recognized by a termination protein, the (A) Rho (ρ) factor (B) σ factor (C) δ factor (D) ε factor
Description : Insulin receptor is made up of (A) One α-and one β-subunit (B) Two α-and two β-subunit (C) Two, α two β-and two γ-subunit (D) One α, one β-one γ-and one δ-subunit
Description : In the insulin receptor, tyrosine kinase domain is present in (A) α-Subunits (B) β-Subunits (C) γ-Subunits (D) δ-Subunits
Description : Daily secretion of insulin is about δ– (A) 10–20 mg (B) 40–50 mg (C) 10–20 units (D) 40–50 units
Description : The nucleotide binding site of G-proteins is present on their (A) α-Subunit (B) β-Subunit α- and β- (C) γ-Subunit (D) δ-Subunit
Description : δ-Cells of islet of langerhans of pancreas produce (A) Pancreatic polypeptide (B) Pancreatic lipase (C) Somatostatin (D) Steapsin
Description : Type δ H chain is present in (A) Ig G (B) Ig A (C) Ig M (D) Ig D
Description : The enzyme δ-aminolevulinate dehydratase contains (A) Zinc (B) Manganese (C) Magnesium (D) Calcium
Description : During synthesis of porphyrins, synthesis of δ-amino levulinic acid occurs in (A) Mitochondria (B) Cytosol (C) Both in mitochondria and cytosol (D) Ribosomes
Description : One of the main functions of Vitamin K is cofactor for (A) Carboxylate for the formation of γ carboxyglutamate (B) Methylation of δ-adenosyl methionine (C) Carboxylation of biotin (D) One carbon transfer by tetrahydrofolate
Description : Neogenesis of methyl group is (A) The availability of methyl group form δ adenosyl methionine (B) The availability of methyl group from betaine (C) Interaction between N5 N10 methylene tetra hydrofolate with a NAD+ dependent reductase (D) Availability of methyl group from methyl B12
Description : The only known physiological methylating agents in the animal organism are (A) Choline and betaine (B) Choline and δ-adenosyl methionine (C) Betaine and δ-adenyosyl methionine (D) Dimehtyl glycine and betaine
Description : All of the following statements about pancreatic somatostain are true except (A) It is secreted by δ cells of islets of Langerhans (B) It stimulates the secretion of gastrin (C) It inhibits the secretion of secretin (D) It inhibits the secretion of cholecystokininpancreozymin