Description : Lack of Glucocorticoids and mineral corticoids might be consequence of which of the following defects in the adrenal cortex? (A) Androstenadione deficiency (B) Estrone deficiency (C) 17 α-OH progesterone deficiency (D) C- α-Hydroxylase deficiency
Last Answer : Answer : D
Description : In adrenogenital syndrome due to total absence of 21-hydroxylase in adrenal cortex, there is (A) Deficient secretion of glucocorticoids (B) Deficient secretion of mineralcorticoids (C) Excessive secretion of androgens (D) All of these
Description : Zona glomerulosa of adrenal cortex synthesises (A) Glucocorticoids (B) Mineralocorticoids (C) Androgens (D) Estrogen and progesterone HORMONE METABOLISM 223
Last Answer : Answer : A
Description : In the biosynthesis of testosterone the rate limiting step is conversion of (A) Cholesterol to pregnenolone (B) Pregnenolone to progesterone (C) Progesterone to 17 α-hydroxy progesterone (D) 17 α-Hydroxy progesterone to androstenedione
Description : What is the cascade of events that follows a stress or trauma to produce adrenal reaction? A) hypothalamus (ACTH-releasing hormone)-anterior pituitary (ACTH)-adrenal cortex mineralocorticoids and ... ) E) adrenal cortex (hormones)-hypothalamus (ACTH-releasing hormone)-anterior pituitary (ACTH)
Last Answer : A) hypothalamus (ACTH-releasing hormone)-anterior pituitary (ACTH)-adrenal cortex mineralocorticoids and glucocorticoids (regulate metabolism and sugar level)
Description : 3-β-Hydroxysteroid dehydrogenase and ∆5,4 isomerase catalyse the conversion of the weak androgen DHEA to (A) Androstenedione (B) Testosterone (C) Progesterone (D) Estrone
Description : Injury to adrenal cortex is not likely to affect the secretion of which one of the following? (a) Aldosterone (b) Both androstenedione and dehydroepiandrosterone (c) Adrenaline (d) Cortisol
Last Answer : (c) Adrenaline
Description : The hormone which regulates the basal metabolism in our body is secreted from (a) adrenal cortex (b) pancreas (c) pituitary (d) thyroid.
Last Answer : d) thyroid.
Description : During late pregnancy, the major source of progesterone is (A) Adrenal cortex (B) Placenta (C) Corpus luteum (D) Graafian follicles
Last Answer : Answer : B
Description : Sertoli cells are found in (a) ovaries and secrete progesterone (b) adrenal cortex and secrete adrenaline (c) seminiferous tubules and provide nutrition to germ cells (d) pancreas and secrete cholecystokinin.
Last Answer : (c) seminiferous tubules and provide nutrition to germ cells
Description : Progesterone is transported in blood by (A) Transcortin (B) Sex hormone binding globulin (C) Albumin (D) Testosterone estrogen binding globulin
Description : Cyclic AMP is formed from ATP by the enzyme adenylate cyclase which is activated by the hormone: (A) Insulin (B) Epinephrine (C) Testosterone (D) Progesterone
Last Answer : B
Description : An androgen which is more powerful than testosterone is (A) Androstenedione (B) Dihydrotestosterone (C) Androsterone (D) Epiandrosterone
Description : The enzyme catalyzing conversion of androstenedione to testosterone is a (A) Oxygenase (B) Dehydrogenase (C) Isomerase (D) Decarboxylase
Description : An inborn error, maple syrup urine disease is due to deficiency of the enzyme: (A) Isovaleryl-CoAhydrogenase (B) Phenylalnine hydroxylase (C) Adenosyl transferase (D) α-Ketoacid decarboxylase
Description : All the following statements about ACTH are true except (A) It is a tropic hormone (B) Its target cells are located in adrenal cortex (C) Its receptors are located in the cell membrane (D) Its second messenger is inositol triphosphate
Description : Mineralcorticoids regulate the metabolism of all of the following except (A) Sodium (B) Potassium (C) Calcium (D) Chloride
Last Answer : Answer : C
Description : Conversion of testosterone to estradiol requires the enzyme: (A) Aromatase (B) Dehydrogenase (C) Lyase (D) Isomerase HORMONE METABOLISM 215
Description : Placenta secretes all of the following except (A) FSH (B) Progesterone (C) Estrogen (D) Chorionic gonadotropin HORMONE METABOLISM 225
Description : The hormone used as an oral contraceptive is – (1) Cortisone (2) Progesterone (3) Testosterone (4) Aldesterone
Last Answer : (2) Progesterone Explanation: It was discovered relatively long ago (1930's) that injections of progesterone were effective as a contraceptive in preventing pregnancies. Progesterone is used as a ... for creating a hostile environment for fertilization and not allowing sperm to enter the egg.
Description : The hormone used as an oral contraceptive is : (1) Cortisone (2) Progesterone (3) Testosterone (4) Aldesterone
Last Answer : Progesterone
Description : All the following statements about transcortin are true except (A) It is synthesised in liver (B) It transports glucocorticoids (C) It transports aldosterone (D) It transports progesterone
Description : Name the hormone secreted by the adrenal cortex. Mention its function.
Last Answer : One of the important hormones secreted by adrenal cortex is cortisone. It regulates the rate of metabolism and the concentration of salts in the blood.
Description : Which disease results when the adrenal cortex produces too much hormone? A) diabetes insipidus B) diabetes mellitus C) Cushing's syndrome D) Addison's disease E) myxedema
Last Answer : C) Cushing's syndrome
Description : Tyrosinosis is due to defect in the enzyme: (A) Fumarylacetoacetate hydrolase (B) p-Hydroxyphenylpyruvate hydroxylase (C) Tyrosine transaminase (D) Tyrosine hydroxylase
Description : Richner-Hanhart syndrome is due to defect in (A) Tyrosinase (B) Phenylalanine hydroxylase (C) Hepatic tyrosine transaminase (D) Fumarylacetoacetate hydrolase
Description : 17-OH progesterone?
Last Answer : Definition17-OH progesterone is a blood test that measures the amount of 17-OH progesterone, a hormone produced by the adrenal glands and gonads.Alternative Names17-hydroxyprogesterone; Progesterone - 17-OHHow ... the blood has been collected, the needle is removed, and the puncture site is covered
Description : A common intermediate in the synthesis of cortisol and aldosterone is (A) Progesterone (B) Testosterone (C) Estradiol (D) None of these
Description : The principal rate limiting step in the biosynthesis of bile acids is at the (A) 7-Hydroxylase reaction (B) 12 α-Hydroxylase reaction (C) Conjugation reaction (D) Deconjugation reaction
Description : Select the progestin preparation for coadministration with estrogen for hormone replacement therapy that does not counteract the beneficial effect of the latter on lipid profile due to lack of ... oral progesterone B. Norethindrone C. Lynestrenol D. Medroxyprogesterone acetate (p. 281-282)
Last Answer : Select the indication for which a progestin is used alone without combining with an estrogen: A. Threatened abortion B. Dysfunctional uterine bleeding C. Hormone replacement therapy D. Premenstrual tension
Description : Which of the following is noted in cushing’s syndrome, a tumor associated disease of the adrenal cortex? (A) Decreased production of epinephrine (B) Excessive production of epinephrine (C) Excessive production of vasopressin (D) Excessive production of cortisol
Description : Steroid hormones are synthesised in all of the following except (A) Testes (B) Ovaries (C) Adrenal medulla (D) Adrenal cortex
Description : Pheochromocytomas are tumours of (A) Adrenal cortex (B) Adrenal medulla (C) Pancreas (D) Bone
Description : Catecholamine hormones are synthesized in the (A) Chromaffin cells of adrenal medulla (B) Zona glomerulosa of adrenal cortex (C) Zona fasciculate of adrenal cortex (D) Zona reticularis of adrenal cortex
Description : In Cushing’s syndrome-a tumour associated disease of adrenal cortex, there is (A) Decreased epinephrine production (B) Excessive cortisol production (C) Excessive epinephrine production (D) Decreased cortsoil production
Description : In human body highest concentration of ascorbic acid is found in (A) Liver (B) Adrenal cortex (C) Adrenal medulla (D) Spleen
Description : Calcitonin is synthesised in (A) Parathyroid glands (B) Thyroid gland (C) Pars intermedia of pituitary (D) Adrenal cortex
Description : Keratan sulphate is found in abundance in (A) Heart muscle (B) Liver (C) Adrenal cortex (D) Cornea
Last Answer : D
Description : The part of the brain controlling the anterior pituitary gland secretions is the A) medulla. B) thalamus. C) cerebral cortex. D) hypothalamus. E) cerebellum. Answer: D ... B) antidiuretic hormone C) gonadotropic hormones D) thyroid-stimulating hormone E) adrenocorticotropic hormone
Last Answer : B) thalamus.
Description : It is unique that the following single antidiabetogenic hormone effectively counter acts the several diabetogenic hormones: (A) Glucagon (B) Glucocorticoids (C) Insulin (D) Growth hormone
Description : ACTH stimulates the secretion of (A) Glucocorticoids (B) Epinephrine (C) Thyroxine (D) Luteinizing hormone
Description : HMG-CoA reductase activity is increased by administration of the hormone: (A) Insulin (B) Glucagon (C) Epinephrine (D) Glucocorticoids
Description : Maple syrup urine disease results from absence or serve deficiency of (A) Homogentisate oxidase (B) Phenylalanine hydroxylase (C) Branched chain amino acid transaminase (D) None of these
Description : A deficiency of copper effects the formation of normal collagen by reducing the activity of which of the following enzyme? (A) Prolyl hydroxylase (B) Lysyl oxidase (C) Lysyl hydroxylase (D) Glucosyl transferase
Description : The deficiency of copper decreases the activity of the enzyme: (A) Lysine oxidase (B) Lysine hydroxylase (C) Tyrosine oxidase (D) Proline hydroxylase
Description : Neonatal tyrosinemia is due to deficiency of the enzyme: (A) p-Hydroxyphenylpyruvate hydroxylase (B) Fumarylacetoacetate hydrolase (C) Phenylalanine hydroxylase (D) Tyrosine dehydrogenase
Description : Albinism is due to deficiency of the enzyme: (A) Phenylalanine hydroxylase (B) Tyrosinase (C) p-Hydroxyphenylpyruvic acid oxidase (D) Tyrosine dehydrogenase
Description : Alkaptonuria occurs due to deficiency of the enzyme: (A) Maleylacetoacetate isomerase (B) Homogentisate oxidase (C) p-Hydroxyphenylpyruvate hydroxylase (D) Fumarylacetoacetate hydrolase
Description : All the following are true about phenylketonuria except (A) Deficiency of phenylalanine hydroxylase (B) Mental retardation (C) Increased urinary excretion of p-hydroxyphenyl pyruvic acid (D) Decrease serotonin formation
Description : Ehlers-Danlos syndrome characterized by hypermobile joints and skin abnormalities is due to (A) Abnormality in gene for procollagen (B) Deficiency of lysyl oxidase (C) Deficiency of prolyl hydroxylase (D) Deficiency of lysyl hydroxylase