Description : Whcih of the following hormone does not activate adenylate cyclase? (A) Epinephrine (B) Glucagon (C) Parathyroid hormone (D) Insulin
Last Answer : Answer : D
Description : The best understood intracellular messenger is cyclic AMP (cAMP). Which of the following statement(s) concerning this intracellular messenger is/are correct? a. Intracellular cyclic AMP is constantly ... of adenylate cyclase d. cAMP is the only cyclic nucleotide active as an intracellular messenger
Last Answer : Answer: a, b The prototypic intracellular messenger is cAMP. To function as a mediator, the concentration of cAMP must change rapidly. In resting cells, cAMP is continuously being degraded by ... produce cGMP. Intracellular calcium ions also serve as second messengers in a large number of cells
Description : Adenylate cyclase is activated by (A) Insulin (B) Glucagon (C) Prostaglandin E1 (D) Ca2+ ions
Last Answer : Answer : B
Description : Adenylate cyclase is activated by (A) GDP-bearing α-Subunit of G-protein (B) GTP-bearing α-Subunit of G-protein (C) GDP-bearing γ-Subunit of G-protein (D) GTP-bearing γ-Subunit of G-protein
Description : Which of the following is activated by Cholera toxin? 1) Adenylate cyclase 2) Guanlyate cyclase 3) Peroxisome proliferator receptor (PPAR) gamma 4) Sodium/potassium ATPase 5) The glucose-sodium transporter
Last Answer : Answers-1 Cholera toxin activates adenylate cyclase with generation of cAMP.
Description : Binding of insulin to its receptor activates (A) Adenylate cyclase (B) Guanylate cyclase (C) Phospholipase C (D) Tyrosine kinase
Description : Which of the following statement(s) is/are true concerning cell membrane receptors? a. The largest family of cell surface receptors are the G-protein-linked receptors b. Activities of the ... through the use adenylate cyclase d. Tyrosine kinase receptors are considered G-protein-linked receptors
Last Answer : Answer: a, c All water-soluble regulatory molecules bind to the cell surface receptor proteins. Binding of the appropriate ligand evokes an intracellular signal which usually regulates ... are adenylate cyclase, which converts ATP to cAMP, and the polyphosphoinositide-specific phospholipase C
Description : The second messenger for many hormones is (A) ATP (B) cyclic AMP (C) cGMP (D) UTP HORMONE METABOLISM 227
Description : Which pair of hormones has opposite, antagonistic effects? A) insulin--glucagon B) insulin--progesterone C) estrogen--thyroxin D) thyroxin--parathyroid hormone E) epinephrine--norepinephrine
Last Answer : A) insulin--glucagon
Description : Cyclic AMP can be formed from (A) AMP (B) ADP (C) ATP (D) All of these
Last Answer : Answer : C
Description : cAMD is destroyed by (A) Adenylate cyclase (B) Phosphodiesterase (C) Synthetase phosphatase (D) Synthetase kinase
Description : Binding of thyroxine to its receptors (A) Activates Adenylate cyclase (B) Activates guanylate cyclase (C) Activates a stimulatory G-protein (D) Increases transcription
Description : Rod cells possess a trans-membrane protein which is (A) Adenylate cyclase (B) Transducin (C) Rhodopsin (D) B as well as C
Description : The receptor transduction mechanism with the fastest time-course of response effectuation is: A. Adenylyl cyclase-cyclic AMP pathway B. Phospholipase C-IP3: DAG pathway C. Intrinsic ion channel operation D. Protein synthesis modulation
Last Answer : C. Intrinsic ion channel operation
Description : 6.4 Several actions of growth hormone are exerted through the elaboration of: A. Cyclic AMP B. Cyclic GMP C. Somatostatin D. Insulin like growth factor-1
Last Answer : D. Insulin like growth factor-1
Description : Protein kinase C is activated by (A) Cyclic AMP (B) Cyclic GMP (C) Diacyl glycerol (D) Inositol triphosphate
Description : Progesterone is transported in blood by (A) Transcortin (B) Sex hormone binding globulin (C) Albumin (D) Testosterone estrogen binding globulin
Last Answer : Answer : A
Description : The defect in adrenal cortex responsible for lack of glucocorticoids and mineralcorticoids is (A) Androstenedione deficiency (B) 17 α -OH progesterone deficiency (C) C-21 hydroxylase deficiency (D) Testosterone deficiency HORMONE METABOLISM 209
Description : All following are naturally occurring nucleotides except (A) Cyclic AMP (B) ATP (C) DNA (D) Inosine monophosphate
Description : Action of glycogen synthase is inhibited by (A) Insulin (B) Glucose (C) Mg2+ (D) Cyclic AMP
Description : Glycogen synthetase activity is depressed by (A) Glucose (B) Insulin (C) Cyclic AMP (D) Fructokinase
Last Answer : C
Description : All the following statements about TSH are true except (A) It is a tropic hormone (B) It acts on para-follicular cells of thyroid glands (C) Its receptors are membrane-bound (D) Its second messenger is cyclic AMP
Description : The hormone used as an oral contraceptive is – (1) Cortisone (2) Progesterone (3) Testosterone (4) Aldesterone
Last Answer : (2) Progesterone Explanation: It was discovered relatively long ago (1930's) that injections of progesterone were effective as a contraceptive in preventing pregnancies. Progesterone is used as a ... for creating a hostile environment for fertilization and not allowing sperm to enter the egg.
Description : The hormone used as an oral contraceptive is : (1) Cortisone (2) Progesterone (3) Testosterone (4) Aldesterone
Last Answer : Progesterone
Description : This hormone has disulphide group: (A) Glucagon (B) Insulin (C) T4 (D) Epinephrine
Description : HMG-CoA reductase activity is increased by administration of the hormone: (A) Insulin (B) Glucagon (C) Epinephrine (D) Glucocorticoids
Description : The output of free fatty acids from adipose tissue is reduced by (A) Insulin (B) Glucagon (C) Growth hormone (D) Epinephrine
Description : The hormone activating the glycogen synthase activity is (A) Insulin (B) Glucagon (C) Epinephrine (D) ACTH
Description : Release of free fatty acids from adipose tissue is increased by all of the following except (A) Glucagon (B) Epinephrine (C) Growth hormone (D) Insulin
Description : Conversion of testosterone to estradiol requires the enzyme: (A) Aromatase (B) Dehydrogenase (C) Lyase (D) Isomerase HORMONE METABOLISM 215
Description : Insulin increases the permeability of glucose across the plasma membrane of muscle cells by (A) Acting on adenylate cycle (B) By loosening the integrity of the membrane (C) Through Ca2 ... membrane cruting the hexose carries of intracellular organelles and making them fuse with the plasma membrane
Description : The enzyme aspartate transcarbamoylase of pyrimidine biosynthesis is inhibited by (A) ATP (B) ADP (C) AMP (D) CTP
Description : The enzyme phosphoenolpyruvate carboxykinase catalyses the conversion of oxaloacetate to phosphoenolpyruvate requires (A) ATP (B) ADP (C) AMP (D) GTP
Description : Phosphofructokinase key enzyme in glycolysis is inhibited by (A) Citrate and ATP (B) AMP (C) ADP (D) TMP
Description : The enzyme acyl-CoA synthase catalyses the conversion of a fatty acid of an active fatty acid in the presence of (A) AMP (B) ADP (C) ATP (D) GTP
Description : Drugs that block the a receptor on effector cells at adrenergic nerve endings (a) Antagonize the effects of isoproterenol on the heart rate (b) Antagonize some of the effects of epinephrine on ... the effects of epinephrine on adenylyl cyclase (d) Cause mydriasis (e) Decreases blood glucose levels
Last Answer : Ans: B
Description : Protein anabolism is stimulated by (A) ACTH (B) Testosterone (C) Glucagon (D) Epinephrine
Description : The following are true about parathyroid hormone a. it is an 84 amino acid peptide hormone b. it increases calcium absorption from the gastrointestinal tract c. it acts on a cell surface receptor that increases intracellular cyclic AMP d. all above
Last Answer : all above
Description : Identify A, B and C in the diagramatic representation of the mechanism of hormone action. B A Response 1 C Physiological Responses Select the correct option from the following. (a) A-Steroid Hormone; B- ... ; C - Second Messenger (d) A-Protein Hormone; B-Cyclic AMP; C-Hormone-receptor Complex
Last Answer : (b) A-Protein Hormone; B-Receptor; C-Cyclic AMP
Description : How does steroid hormone influence the cellular activities? (a) Using aquaporin channels ‘as second messenger’ (b) Changing the permeability of the cell membrane (c) Binding to DNA and forming a gene-hormone complex (d) Activating cyclic AMP located on the cell membrane
Last Answer : (c) Binding to DNA and forming a gene-hormone complex
Description : Which does NOT occur in a cell stimulated by a steroid hormone? A) The steroid hormone enters the cell by crossing the plasma membrane. B) The hormone binds to a receptor molecule in the ... activates certain genes. E) DNA is transcribed, mRNA is translated, and the result is protein synthesis.
Last Answer : C) The second messenger cyclic AMP is stimulated by the hormone-receptor complex. D) The hormone-receptor complex binds the chromatin and activates certain genes.
Description : Which is associated with a steroid hormone? A) cyclic AMP B) the second messenger system C) production of new proteins D) activation of proteins present in an inactive form E) binding of a protein to a surface receptor on the plasma membrane
Last Answer : C) production of new proteins
Description : A common intermediate in the synthesis of cortisol and aldosterone is (A) Progesterone (B) Testosterone (C) Estradiol (D) None of these
Description : In the biosynthesis of testosterone the rate limiting step is conversion of (A) Cholesterol to pregnenolone (B) Pregnenolone to progesterone (C) Progesterone to 17 α-hydroxy progesterone (D) 17 α-Hydroxy progesterone to androstenedione
Description : 3-β-Hydroxysteroid dehydrogenase and ∆5,4 isomerase catalyse the conversion of the weak androgen DHEA to (A) Androstenedione (B) Testosterone (C) Progesterone (D) Estrone
Description : Which statement is NOT true about non-steroid (peptide) hormones? A) They are derived from peptides, proteins, polypeptides, and derivatives of amino acids. B) They bind to receptors on the cell surface. ... They create an enzyme cascade effect. E) They enter the cell in order to have an effect.
Last Answer : E) They enter the cell in order to have an effect.
Description : The first human hormone produced by recombinant DNA technology is (a) insulin (b) estrogen (c) thyroxin (d) progesterone
Last Answer : (a) insulin
Description : UDP and UTP are formed by phosphorylation from (A) AMP (B) ADP (C) ATP (D) GTP
Description : Cyclic GMP acts as the second messenger for (A) Nerve growth factor (B) Atrial natriuretic factor (C) Epinephrine (D) Norepinephrine