Description : The protein IRS-1 is phosphorylated by (A) Protein kinase A (B) Protein kinase C (C) Tyrosine kinase activity of insulin receptor (D) Tyrosine kinase activity of IGF-1 receptor
Last Answer : Answer : B
Description : With regard to membrane receptors for hormones: a. they are often glycoproteins b. they are important for hormones made up of steroid c. those for insulin exhibit an intrinsic protein kinase activity d. glucagon uses calcium as a second messenger
Last Answer : they are often glycoproteins
Description : Duodenum has characteristic Brunner’s gland which secrete two hormones called (a) kinase, estrogen (b) secretin, cholecystokinin (c) prolactin, parathormone (d) estradiol, progesterone
Last Answer : (b) secretin, cholecystokinin
Description : Select the correct matching of a hormone, its source and function. Hormone Source Function (a) Vasopressin Posterior Increases loss pituitary of water through urine (b) Norepine- Adrenal ... (d) Prolactin Posterior Regulates growth pituitary of mammary glands and milk formation in females
Last Answer : (b) Norepine- Adrenal Increases heart phrine medulla beat, rate of respiration and alterness
Description : Binding of insulin to its receptor activates (A) Adenylate cyclase (B) Guanylate cyclase (C) Phospholipase C (D) Tyrosine kinase
Last Answer : Answer : D
Description : In the insulin receptor, tyrosine kinase domain is present in (A) α-Subunits (B) β-Subunits (C) γ-Subunits (D) δ-Subunits
Description : Tyrosine kinase activity is present in (A) α-Adrenergic receptors (B) β-Adrenergic receptors (C) Cholinergic receptors (D) Insulin receptors
Description : Insulin decreases the activity of (A) cAMP dependent protein kinase (B) HMG CoA-reductas (C) Phosphodiesterase (D) Acetyl CoA-carboxylase
Last Answer : Answer : A
Description : Insulin increases the activity of (A) Pyruvate kinase (B) Phosphorylase (C) Triacylglycerol kinase (D) Fructose 2, 6-bisphosphatase
Description : Insulin has no effect on the activity of the enzyme: (A) Glycogen synthetase (B) Fructokinase (C) Pyruvate kinase (D) Pyruvate dehydrogenase
Description : Which one of the following statements concerning glucose metabolism is correct? (A) The conversion of Glucose to lactate occurs only in the R.B.C (B) Glucose enters most cells by a mechanism in ... ) An elevated level of insulin leads to a decreased level of fructose 2, 6-bisphosphate in hepatocyte
Last Answer : C
Description : All the following hormones promote hyperglycemia except (A) Epinephrine (B) Norepinephrine (C) Insulin (D) Glucagon
Last Answer : Answer : C
Description : Which one of the following hormones is derived most completely from tyrosine? (A) Glucagon (B) Thyroxine (C) Insulin (D) Prostaglandins
Description : Which of the following statements is correct? (A) Thyroxine inhibits utilization of glucose (B) Insulin increases utilization of glucose (C) Glucagon promotes muscle glycogenolysis (D) Insulin inhibits lipogenesis from carbohydrates
Description : It is unique that the following single antidiabetogenic hormone effectively counter acts the several diabetogenic hormones: (A) Glucagon (B) Glucocorticoids (C) Insulin (D) Growth hormone
Description : This pancreatic hormone promotes hypogenesis: (A) Insulin (B) Glucagon (C) Stomato station (D) Pancreozymine
Description : Which of the following does not have disulphide bond? (A) Oxytocin (B) Vasopressin (C) Insulin (D) Glucagon
Description : This hormone has disulphide group: (A) Glucagon (B) Insulin (C) T4 (D) Epinephrine
Description : Which of the following hormones are synthesized as prehormones (A) Vasopressin and oxytocin (B) Growth hormone and insulin (C) Insulin and parathyroid hormone (D) Insulin and Glucagon
Description : Whcih of the following hormone does not activate adenylate cyclase? (A) Epinephrine (B) Glucagon (C) Parathyroid hormone (D) Insulin
Description : This pancreatic hormone increases the blood-sugar level: (A) Insulin (B) Glucagon (C) Pancreozymin (D) Pancreatic polypeptide
Description : Secretion of Insulin-like Growth Factor-I is promoted by (A) Insulin (B) Glucagon (C) Growth hormone (D) Somatomedin C
Description : Diabetes insipidus is caused by deficient secretion of (A) Insulin (B) Glucagon (C) Vasopressin (D) Oxytocin
Description : The α-cells of pancreas islets produce (A) Insulin (B) Glucagon (C) Somatostatin (D) Pancreatic polypeptide
Description : The primary stimulus for insulin secretion is increased. (A) Blood level of epinephrine (B) Blood level of glucagon (C) Blood level of glucose (D) Water intake
Description : β-cells of islet of langerhans of the pancreas secrete (A) Insulin (B) Glucagon (C) Somatostatin (D) Pancreatic polypeptide
Description : Acromegaly results due to excessive release of (A) Thyroxine (B) Growth hormone (C) Insulin (D) Glucagon
Description : Chromium is potentiator of (A) Insulin (B) Glucagon (C) Thyroxine (D) Parathromone
Description : Adenylate cyclase is activated by (A) Insulin (B) Glucagon (C) Prostaglandin E1 (D) Ca2+ ions
Description : Hepatic glycogenoloysis is increased by (A) Insulin (B) Glucagon (C) Epinephrine (D) Glucocorticoids ENZYMES 163
Description : Glycogenoloysis is increased by (A) Glucagon (B) Insulin (C) Epinephrine (D) cAMP
Description : HMG-CoA reductase activity is increased by administration of the hormone: (A) Insulin (B) Glucagon (C) Epinephrine (D) Glucocorticoids
Description : The output of free fatty acids from adipose tissue is reduced by (A) Insulin (B) Glucagon (C) Growth hormone (D) Epinephrine
Description : The desaturation and chain elongation system of polyunsaturated fatty acid are enhanced by (A) Insulin (B) Glucagon (C) Epinephrine (D) Thyroxine
Description : The hormone activating the glycogen synthase activity is (A) Insulin (B) Glucagon (C) Epinephrine (D) ACTH
Description : The harmone acting directly on intestinal mucosa and stimulating glucose absorption is (A) Insulin (B) Glucagon (C) Thyroxine (D) Vasopressin
Description : Which of the following hormone increases the absorption of glucose from G.I.T? (A) Insulin (B) Throid hormones (C) Glucagon (D) FSH
Description : Release of free fatty acids from adipose tissue is increased by all of the following except (A) Glucagon (B) Epinephrine (C) Growth hormone (D) Insulin
Description : Hepatic liponenesis is stimulated by: (A) cAMP (B) Glucagon (C) Epinephrine (D) Insulin
Description : α Cells of Islets of Langerhans secrete (A) Insulin (B) Glucagon (C) Somatostatin (D) Cholecystokinin
Description : Reactivation of inactive liver phosphorylase is normally favoured by (A) Insulin (B) Epinephrine (C) ACTH (D) Glucagon
Last Answer : D
Description : Gluconeogenesis is decreased by (A) Glucagon (B) Epinephrine (C) Glucocorticoids (D) Insulin
Description : The best understood intracellular messenger is cyclic AMP (cAMP). Which of the following statement(s) concerning this intracellular messenger is/are correct? a. Intracellular cyclic AMP is constantly ... of adenylate cyclase d. cAMP is the only cyclic nucleotide active as an intracellular messenger
Last Answer : Answer: a, b The prototypic intracellular messenger is cAMP. To function as a mediator, the concentration of cAMP must change rapidly. In resting cells, cAMP is continuously being degraded by ... produce cGMP. Intracellular calcium ions also serve as second messengers in a large number of cells
Description : The effects of stress include: a. increased testosterone secretion b. decreased insulin secretion c. increased prolactin secretion d. increased ADH secretion
Last Answer : . increased ADH secretion
Description : Which one of the following pairs correctly matches a hormone with a disease resulting from its deficiency ? (a) Relaxin – Gigantism (b) Prolactin – Cretinism (c) Parathyroid hormone – Tetany (d) Insulin – Diabetes insipidus
Last Answer : (c) Parathyroid hormone – Tetany
Description : Which of the following regulates lipolysis in adipocytes? (A) Activation of fatty acid synthesis mediated by CAMP (B) Glycerol phosphorylation to prevent futile esterification of fatty acids (C) ... result of hormone stimulated increases in CAMP levels (D) Activation of CAMP production by Insulin
Description : During mechanism of action of insulin, protein kinase C is activated by
Last Answer : During mechanism of action of insulin, protein kinase C is activated by A. `PIP_2` B. `IP_3` C. `DG ` D. `Ca^(2+)`
Description : The insulin receptor is a: A. Ion channel regulating receptor B. Tyrosine protein kinase receptor C. G-protein coupled receptor D. None of the above
Last Answer : B. Tyrosine protein kinase receptor
Description : A 55-year-old male undergoes a total abdominal colectomy. Which of the following statement(s) is/are true concerning the hormonal response to the surgical procedure? a. Adrenocorticotropic ... in serum insulin and a fall in glucagon accelerate hepatic glucose production and maintain gluconeogenesis
Last Answer : Answer: a, c One of the earliest consequence of a surgical procedure is the rise in levels of circulating cortisol that occur in response to a sudden outpouring of ACTH ... hepatic glucose production, and, with other hormones (epinephrine and glucocorticoids), gluconeogenesis is maintained
Description : Hepatic abnormalities have been noted in adults since the beginning of hyperalimentation. Which of the following statements are true? A. Hepatic steatosis appears to be associated with an overload ... insulin-glucagon ratio are thought to be causative of hepatic steatosis in experimental animals.
Last Answer : Answer: AD DISCUSSION: The most common metabolic complication of TPN in adults is hepatic steatosis. Unlike the hepatic abnormalities in children, which may progress to cholestasis, liver damage, ... glucagon, which is elicited by certain amino acids, results in the mobilization of hepatic lipid