DefinitionCholestasis is any condition in which the flow of bile from the liver is blocked.Alternative NamesIntrahepatic cholestasis; Extrahepatic cholestasisCauses, incidence, and risk factorsThere are many causes of cholestasis.Extrahepatic cholestasis occurs outside the liver. It can be caused by:Bile duct tumorsCystsNarrowing of the bile duct (strictures)Stones in the common bile ductPancreatitisPancreatic tumor or pseudocystPressure on an organ due to a nearby mass or tumorPrimary sclerosing cholangitisIntrahepatic cholestasis occurs inside the liver. It can be caused by:Alcoholic liver diseaseAmyloidosisBacterial abscess in the liverBeing fed through a vein (IV)LymphomaPregnancyPrimary biliary cirrhosisPrimary sclerosing cholangitisSarcoidosisSerious infections that have spread throu