DefinitionDrug-induced cholestasis is a slowing of the flow of bile from the liver that results from medication use.Alternative NamesCholestasis - drug-inducedCauses, incidence, and risk factorsBile is produced in the liver, moved via the bile duct to the gallbladder, and released into the gut through the biliary tract. It helps the body digest fats.Certain drugs can slow or stop the flow of bile from the liver to the gallbladder and gut, which may damage the liver.Many drugs can cause cholestasis, including:Ampicillin and other penicillin-based antibioticsAnabolic steroidsChlorpromazineCimetidineErythromycin estolateEstradiolGold saltsImipramineNitrofurantoinOral contraceptivesProchlorperazineSulindacTerbinafineTolbutamideSymptomsFever or rash from the drugItchingNauseaPain in the upper r